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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Webinars

    • JAN 25, 2022 | 9:00 AM
      HIV-1 Genotyping Targeting Integrase - Perspectives on Surveillance of Antiretroviral Drug Resistance
      HIV-1 Genotyping Targeting Integrase - Perspectives on Surveillance...
      Date: January 25, 2022 Time: 8:00am (CET) 9:00AM (SAST) Globally, in 2020, 38 million people were living with HIV with an additional 1.5 million newly i...
      Speaker: Kim Steegen, PhD, MSc , Natasha Wood, PhD , Steve Williams, PhD
      Sponsored By: Thermo Fisher Scientific
      26
      JAN 11, 2022 | 8:00 AM
      How connected biological safety cabinets can support your lab - best practices today & future trends
      How connected biological safety cabinets can support your lab...
      Date: January 11, 2022 Time: 08:00am (PST), 11:004am (EST) Connectivity of laboratory equipment is progressing rapidly. While it started with the possibility to export data from the equipmen...
      Speaker: David Phillips
      Sponsored By: Thermo Fisher Scientific
      18 1
      DEC 15, 2021 | 11:00 AM
      Glassware Washers and Result Reliability: Wash Worry Away
      Glassware Washers and Result Reliability: Wash Worry Away
      Date: December 15, 2021 Time: 11:00am (PST), 2:00pm (EST) Glassware washers (GWW) serve two important roles in today's dynamic laboratory environment. First, by automating a routine task...
      Speaker: Jordan Henderson
      Sponsored By: Labconco
      5
      DEC 08, 2021 | 8:00 AM
      Next-generation dendritic cell-based vaccines
      Next-generation dendritic cell-based vaccines
      Date: December 08, 2021 Time: 8:00am (PDT), 11:00am (EDT) Learn how enrichment of primary dendritic cell (DC) subsets and sustainable DC manufacturing advances DC-based cell therapies. In th...
      Speaker: Cristina Conforti Andreoni , Marius Döring
      Sponsored By: Miltenyi Biotec
      7
      DEC 08, 2021 | 7:00 AM
      Troubleshooting in bioprocessing
      Troubleshooting in bioprocessing
      Date: December 08, 2021 Time: 7:00am (PDT), 10:00am (EDT) Successful bioprocessing is complex and depends on many factors. From the selection of the expression host, media composition, the p...
      Speaker: Ines Hartmann , Eric Timmermans
      Sponsored By: Eppendorf
      12
      NOV 17, 2021 | 8:00 AM
      Exosomes: From pure isolation to standardized analysis by flow cytometry
      Exosomes: From pure isolation to standardized analysis by flow...
      Date: November 17, 2021 Time: 8:00am (PDT), 11:00am (EDT) From waste disposal to promising biomarkers and therapeutic agents, exosomes and other extracellular vesicles are valuable in resear...
      Speaker: Ariadna Pascual Velazquez , Laura Müller , Stefan Wild, PhD
      Sponsored By: Miltenyi Biotec
      9
      NOV 17, 2021 | 7:00 AM
      CRISPR-based transcriptional activation tools for silent genes in filamentous fungi
      CRISPR-based transcriptional activation tools for silent genes...
      DATE: November 17, 2021 TIME: 7:00am PST, 10:00am EST, 4:00pm CET Filamentous fungi are historically known to be a rich reservoir of bioactive compounds that are applied in a myriad of field...
      Speaker: Laszlo Mozsik
      Sponsored By: GenScript
      13 2
      NOV 16, 2021 | 9:00 AM
      Newton's Cradle: Exploring rational and empirical design space with Engineering Biology
      Newton's Cradle: Exploring rational and empirical design space...
      Date: November 16, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Discovery in biological research was historically driven by empirical methods. The advent of biological engineering, propelled by te...
      Speaker: Patrick Westfall, PhD
      Sponsored By: Inscripta
      2
      NOV 16, 2021 | 8:00 AM
      How to translate a Treg cell research workflow to clinical-grade manufacturing
      How to translate a Treg cell research workflow to clinical-grade...
      Date: November 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) The unique suppressive function of regulatory T cells (Treg cells) makes them an interesting target cell population to study. In rec...
      Speaker: Niloufar Monhasery
      Sponsored By: Miltenyi Biotec
      2
      NOV 15, 2021 | 6:00 AM
      Fully automated RNA library preparation for sequencing respiratory viruses
      Fully automated RNA library preparation for sequencing respiratory...
      Date: November 15, 2021 Time: 6:00am (PDT), 9:00am (EDT) Targeted sequencing of respiratory viruses’ genomes is important to identify novel viral variants. Compared to amplicon sequenc...
      Speaker: Dr. Tomasz Zemojtel , Randy Pares
      Sponsored By: Beckman Coulter Life Sciences
      6
      NOV 09, 2021 | 11:00 AM
      Chemical cytoprotection for stress-free use of human stem cells in basic and translational research
      Chemical cytoprotection for stress-free use of human stem cells...
      Date: November 09, 2021 Time: 11:00am (PDT), 02:00pm (EDT) Clinical translation of human pluripotent stem cells (hPSCs) requires advanced strategies that ensure safe and robust long-term gro...
      Speaker: Dr. Ilyas Singeç
      Sponsored By: Namocell
      5
      NOV 04, 2021 | 8:00 AM
      Label 3Differently - how 3D-IF-validated antibodies provide clear signals from cleared tissues in large-scale 3D imaging
      Label 3Differently - how 3D-IF-validated antibodies provide clear...
      Date: November 4, 2021 Time: 8:00am (PDT), 11:00am (EDT) The promise of tissue clearing techniques in combination with 3D-immunofluorescence (IF) microscopy is revolutionary. Complex biologi...
      Speaker: Dr. Markus Habich
      Sponsored By: Miltenyi Biotec
      2
      NOV 03, 2021 | 10:00 AM
      Streamline your path from immunodiagnostic development to commercialization
      Streamline your path from immunodiagnostic development to commercialization
      Date: November 3, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Developing and commercializing immunodiagnostic assays are challenging and time-consuming. Selecting the best combination of tools an...
      Speaker: Anthony Chiulli
      Sponsored By: Thermo Fisher Scientific
      3
      NOV 03, 2021 | 7:00 AM
      Fully humanized mouse models for Immuno-Oncology preclinical drug candidate selection
      Fully humanized mouse models for Immuno-Oncology preclinical drug...
      Date: November 3, 2021 Time: 7:00am (PDT), 10:00am (EDT) The reconstitution of a fully functional human immune system in mouse after engraftment of purified hCD34+ hematopoietic cells provid...
      Speaker: Sébastien Tabruyn
      Sponsored By: Miltenyi Biotec
      5
      OCT 28, 2021 | 8:00 AM
      How to Advance Cell & Gene Therapies with an Innovative, Flexible Approach
      How to Advance Cell & Gene Therapies with an Innovative, Flexible...
      Date: October 28, 2021 Time: 8:00am (PDT), 11:00am (EDT) Today’s health industry is leveraging new, cutting-edge Cell & Gene Therapies (CGTs) to address a variety of medical illnes...
      Speaker: ​​​​​​​Chris ​Andrews , Domenico Palumberi
      Sponsored By: Dassault Systèmes
      6
      OCT 20, 2021 | 9:00 AM
      Membrane Proteins: From gene to cryo-EM structure with Thermo Fisher GeneArt and Salipro Biotech
      Membrane Proteins: From gene to cryo-EM structure with Thermo...
      Date: October 20, 2021 Time: 9:00am PDT Cryo-electron microscopy (cryo-EM) is rapidly evolving to be the primary tool for structure determination of membrane proteins. However, generation of...
      Speaker: Ieva Drulyte, PhD , Michael Liss, PhD , Jens Frauenfeld, PhD
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific
      4
      OCT 14, 2021 | 9:00 AM
      Session 3: Simple steps to publication-quality western blots
      Session 3: Simple steps to publication-quality western blots
      Date: October 14, 2021 Time: 9:00am (PDT), 12:00pm (EDT), 5:00pm GMT Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring spe...
      Speaker: Kelli Feather-Henigan
      Presented at: Webinar series: Simple steps to publication-quality western blots
      Sponsored By: Thermo Fisher Scientific
      28
      OCT 14, 2021 | 8:00 AM
      Ensure reproducibility in your B cell analysis
      Ensure reproducibility in your B cell analysis
      Date: October 14, 2021 Time: 8:00am (PDT), 11:00am (EDT) The primary role of B cells is to secrete antibodies, boosting our adaptive immune responses, making them an essential part of our im...
      Speaker: Urmi Roy, PhD , Dr. Susanne Bethke
      Sponsored By: Miltenyi Biotec
      15
      OCT 13, 2021 | 7:00 AM
      Session 2: Simple steps to publication-quality western blots
      Session 2: Simple steps to publication-quality western blots
      Date: October 13, 2021 Time: 7:00am (PDT), 10:00am (EDT) Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring specific target...
      Speaker: Caleb Shearrow
      Presented at: Webinar series: Simple steps to publication-quality western blots
      Sponsored By: Thermo Fisher Scientific
      31 1
      OCT 13, 2021 | 6:00 AM
      Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2 Human Monoclonal Antibodies
      Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2...
      We’ll discuss the rapid discovery efforts to identify human monoclonal antibody drugs that protect against COVID-19. We will review the technologies used to find antibodies, the optima...
      Speaker: James Crowe, MD
      Presented at: Coronavirus Series
      26
      OCT 12, 2021 | 5:00 PM
      Session 1: Simple steps to publication-quality western blots
      Session 1: Simple steps to publication-quality western blots
      Date: October 12, 2021 Time: 5:00pm (PDT), 8:00pm (EDT) 222 Learning Objectives 222 222 222 Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved...
      Speaker: Jordan Thompson, PhD
      Presented at: Webinar series: Simple steps to publication-quality western blots
      Sponsored By: Thermo Fisher Scientific
      39 1
      OCT 12, 2021 | 8:00 AM
      The growing concern of off-target effects: How to measure and minimize off-target effects in your genome editing experiments.
      The growing concern of off-target effects: How to measure and...
      Date: October 12, 2021 Time: 8:00am (PDT), 11:00am (EDT) CRISPR-Cas9 is a nuclease-based genome editing system which has seen exponential growth in adoption with broad applications from basi...
      Speaker: Pandhita Pochanard
      Sponsored By: Thermo Fisher Scientific/Gibco
      30
      OCT 07, 2021 | 10:00 AM
      Optimizing tumor study performance:  Evaluating the B-NDG & NSGâ„¢ models in PDX and CDX tumor studies.
      Optimizing tumor study performance: Evaluating the B-NDG & NSGâ„¢...
      Date: October 07, 2021 Time: 10:00am (PDT), 1:00pm (EDT) It's estimated than less than 10% of investigational anti-cancer drugs successfully achieve FDA approval for clinical use. This i...
      Speaker: Viktoria Hyddmark
      Sponsored By: Envigo
      3 1
      OCT 07, 2021 | 7:00 AM
      Troubleshooting Cell-based Assays - Ask the Experts to Avoid Common Pitfalls from Cell Seeding to Analysis
      Troubleshooting Cell-based Assays - Ask the Experts to Avoid Common...
      DATE: October 7, 2021 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
      Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
      Sponsored By: Eppendorf, Promega
      12
    JAN 25, 2022 | 9:00 AM
    HIV-1 Genotyping Targeting Integrase - Perspectives on Surveillance of Antiretroviral Drug Resistance
    HIV-1 Genotyping Targeting Integrase - Perspectives on Surveillance...
    Date: January 25, 2022 Time: 8:00am (CET) 9:00AM (SAST) Globally, in 2020, 38 million people were living with HIV with an additional 1.5 million newly i...
    Speaker: Kim Steegen, PhD, MSc , Natasha Wood, PhD , Steve Williams, PhD
    Sponsored By: Thermo Fisher Scientific
    26
    JAN 11, 2022 | 8:00 AM
    How connected biological safety cabinets can support your lab - best practices today & future trends
    How connected biological safety cabinets can support your lab...
    Date: January 11, 2022 Time: 08:00am (PST), 11:004am (EST) Connectivity of laboratory equipment is progressing rapidly. While it started with the possibility to export data from the equipmen...
    Speaker: David Phillips
    Sponsored By: Thermo Fisher Scientific
    18 1
    DEC 15, 2021 | 11:00 AM
    Glassware Washers and Result Reliability: Wash Worry Away
    Glassware Washers and Result Reliability: Wash Worry Away
    Date: December 15, 2021 Time: 11:00am (PST), 2:00pm (EST) Glassware washers (GWW) serve two important roles in today's dynamic laboratory environment. First, by automating a routine task...
    Speaker: Jordan Henderson
    Sponsored By: Labconco
    5
    DEC 08, 2021 | 8:00 AM
    Next-generation dendritic cell-based vaccines
    Next-generation dendritic cell-based vaccines
    Date: December 08, 2021 Time: 8:00am (PDT), 11:00am (EDT) Learn how enrichment of primary dendritic cell (DC) subsets and sustainable DC manufacturing advances DC-based cell therapies. In th...
    Speaker: Cristina Conforti Andreoni , Marius Döring
    Sponsored By: Miltenyi Biotec
    7
    DEC 08, 2021 | 7:00 AM
    Troubleshooting in bioprocessing
    Troubleshooting in bioprocessing
    Date: December 08, 2021 Time: 7:00am (PDT), 10:00am (EDT) Successful bioprocessing is complex and depends on many factors. From the selection of the expression host, media composition, the p...
    Speaker: Ines Hartmann , Eric Timmermans
    Sponsored By: Eppendorf
    12
     
     
  • NOV 17, 2021 | 8:00 AM
    Exosomes: From pure isolation to standardized analysis by flow cytometry
    Exosomes: From pure isolation to standardized analysis by flow...
    Date: November 17, 2021 Time: 8:00am (PDT), 11:00am (EDT) From waste disposal to promising biomarkers and therapeutic agents, exosomes and other extracellular vesicles are valuable in resear...
    Speaker: Ariadna Pascual Velazquez , Laura Müller , Stefan Wild, PhD
    Sponsored By: Miltenyi Biotec
    9
    NOV 17, 2021 | 7:00 AM
    CRISPR-based transcriptional activation tools for silent genes in filamentous fungi
    CRISPR-based transcriptional activation tools for silent genes...
    DATE: November 17, 2021 TIME: 7:00am PST, 10:00am EST, 4:00pm CET Filamentous fungi are historically known to be a rich reservoir of bioactive compounds that are applied in a myriad of field...
    Speaker: Laszlo Mozsik
    Sponsored By: GenScript
    13 2
    NOV 16, 2021 | 9:00 AM
    Newton's Cradle: Exploring rational and empirical design space with Engineering Biology
    Newton's Cradle: Exploring rational and empirical design space...
    Date: November 16, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Discovery in biological research was historically driven by empirical methods. The advent of biological engineering, propelled by te...
    Speaker: Patrick Westfall, PhD
    Sponsored By: Inscripta
    2
    NOV 16, 2021 | 8:00 AM
    How to translate a Treg cell research workflow to clinical-grade manufacturing
    How to translate a Treg cell research workflow to clinical-grade...
    Date: November 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) The unique suppressive function of regulatory T cells (Treg cells) makes them an interesting target cell population to study. In rec...
    Speaker: Niloufar Monhasery
    Sponsored By: Miltenyi Biotec
    2
    NOV 15, 2021 | 6:00 AM
    Fully automated RNA library preparation for sequencing respiratory viruses
    Fully automated RNA library preparation for sequencing respiratory...
    Date: November 15, 2021 Time: 6:00am (PDT), 9:00am (EDT) Targeted sequencing of respiratory viruses’ genomes is important to identify novel viral variants. Compared to amplicon sequenc...
    Speaker: Dr. Tomasz Zemojtel , Randy Pares
    Sponsored By: Beckman Coulter Life Sciences
    6
     
     
  • NOV 09, 2021 | 11:00 AM
    Chemical cytoprotection for stress-free use of human stem cells in basic and translational research
    Chemical cytoprotection for stress-free use of human stem cells...
    Date: November 09, 2021 Time: 11:00am (PDT), 02:00pm (EDT) Clinical translation of human pluripotent stem cells (hPSCs) requires advanced strategies that ensure safe and robust long-term gro...
    Speaker: Dr. Ilyas Singeç
    Sponsored By: Namocell
    5
    NOV 04, 2021 | 8:00 AM
    Label 3Differently - how 3D-IF-validated antibodies provide clear signals from cleared tissues in large-scale 3D imaging
    Label 3Differently - how 3D-IF-validated antibodies provide clear...
    Date: November 4, 2021 Time: 8:00am (PDT), 11:00am (EDT) The promise of tissue clearing techniques in combination with 3D-immunofluorescence (IF) microscopy is revolutionary. Complex biologi...
    Speaker: Dr. Markus Habich
    Sponsored By: Miltenyi Biotec
    2
    NOV 03, 2021 | 10:00 AM
    Streamline your path from immunodiagnostic development to commercialization
    Streamline your path from immunodiagnostic development to commercialization
    Date: November 3, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Developing and commercializing immunodiagnostic assays are challenging and time-consuming. Selecting the best combination of tools an...
    Speaker: Anthony Chiulli
    Sponsored By: Thermo Fisher Scientific
    3
    NOV 03, 2021 | 7:00 AM
    Fully humanized mouse models for Immuno-Oncology preclinical drug candidate selection
    Fully humanized mouse models for Immuno-Oncology preclinical drug...
    Date: November 3, 2021 Time: 7:00am (PDT), 10:00am (EDT) The reconstitution of a fully functional human immune system in mouse after engraftment of purified hCD34+ hematopoietic cells provid...
    Speaker: Sébastien Tabruyn
    Sponsored By: Miltenyi Biotec
    5
    OCT 28, 2021 | 8:00 AM
    How to Advance Cell & Gene Therapies with an Innovative, Flexible Approach
    How to Advance Cell & Gene Therapies with an Innovative, Flexible...
    Date: October 28, 2021 Time: 8:00am (PDT), 11:00am (EDT) Today’s health industry is leveraging new, cutting-edge Cell & Gene Therapies (CGTs) to address a variety of medical illnes...
    Speaker: ​​​​​​​Chris ​Andrews , Domenico Palumberi
    Sponsored By: Dassault Systèmes
    6
     
     
  • OCT 20, 2021 | 9:00 AM
    Membrane Proteins: From gene to cryo-EM structure with Thermo Fisher GeneArt and Salipro Biotech
    Membrane Proteins: From gene to cryo-EM structure with Thermo...
    Date: October 20, 2021 Time: 9:00am PDT Cryo-electron microscopy (cryo-EM) is rapidly evolving to be the primary tool for structure determination of membrane proteins. However, generation of...
    Speaker: Ieva Drulyte, PhD , Michael Liss, PhD , Jens Frauenfeld, PhD
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific
    4
    OCT 14, 2021 | 9:00 AM
    Session 3: Simple steps to publication-quality western blots
    Session 3: Simple steps to publication-quality western blots
    Date: October 14, 2021 Time: 9:00am (PDT), 12:00pm (EDT), 5:00pm GMT Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring spe...
    Speaker: Kelli Feather-Henigan
    Presented at: Webinar series: Simple steps to publication-quality western blots
    Sponsored By: Thermo Fisher Scientific
    28
    OCT 14, 2021 | 8:00 AM
    Ensure reproducibility in your B cell analysis
    Ensure reproducibility in your B cell analysis
    Date: October 14, 2021 Time: 8:00am (PDT), 11:00am (EDT) The primary role of B cells is to secrete antibodies, boosting our adaptive immune responses, making them an essential part of our im...
    Speaker: Urmi Roy, PhD , Dr. Susanne Bethke
    Sponsored By: Miltenyi Biotec
    15
    OCT 13, 2021 | 7:00 AM
    Session 2: Simple steps to publication-quality western blots
    Session 2: Simple steps to publication-quality western blots
    Date: October 13, 2021 Time: 7:00am (PDT), 10:00am (EDT) Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring specific target...
    Speaker: Caleb Shearrow
    Presented at: Webinar series: Simple steps to publication-quality western blots
    Sponsored By: Thermo Fisher Scientific
    31 1
    OCT 13, 2021 | 6:00 AM
    Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2 Human Monoclonal Antibodies
    Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2...
    We’ll discuss the rapid discovery efforts to identify human monoclonal antibody drugs that protect against COVID-19. We will review the technologies used to find antibodies, the optima...
    Speaker: James Crowe, MD
    Presented at: Coronavirus Series
    26
     
     
  • OCT 12, 2021 | 5:00 PM
    Session 1: Simple steps to publication-quality western blots
    Session 1: Simple steps to publication-quality western blots
    Date: October 12, 2021 Time: 5:00pm (PDT), 8:00pm (EDT) 222 Learning Objectives 222 222 222 Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved...
    Speaker: Jordan Thompson, PhD
    Presented at: Webinar series: Simple steps to publication-quality western blots
    Sponsored By: Thermo Fisher Scientific
    39 1
    OCT 12, 2021 | 8:00 AM
    The growing concern of off-target effects: How to measure and minimize off-target effects in your genome editing experiments.
    The growing concern of off-target effects: How to measure and...
    Date: October 12, 2021 Time: 8:00am (PDT), 11:00am (EDT) CRISPR-Cas9 is a nuclease-based genome editing system which has seen exponential growth in adoption with broad applications from basi...
    Speaker: Pandhita Pochanard
    Sponsored By: Thermo Fisher Scientific/Gibco
    30
    OCT 07, 2021 | 10:00 AM
    Optimizing tumor study performance:  Evaluating the B-NDG & NSGâ„¢ models in PDX and CDX tumor studies.
    Optimizing tumor study performance: Evaluating the B-NDG & NSGâ„¢...
    Date: October 07, 2021 Time: 10:00am (PDT), 1:00pm (EDT) It's estimated than less than 10% of investigational anti-cancer drugs successfully achieve FDA approval for clinical use. This i...
    Speaker: Viktoria Hyddmark
    Sponsored By: Envigo
    3 1
    OCT 07, 2021 | 7:00 AM
    Troubleshooting Cell-based Assays - Ask the Experts to Avoid Common Pitfalls from Cell Seeding to Analysis
    Troubleshooting Cell-based Assays - Ask the Experts to Avoid Common...
    DATE: October 7, 2021 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
    Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
    Sponsored By: Eppendorf, Promega
    12
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