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    Gene Editing

    Gene Editing: a type of genetic engineering in which DNA is inserted, deleted or replaced in the genome of a living organism using engineered nucleases, or "molecular scissors". These nucleases create site-specific double-strand breaks (DSBs) at desired locations in the genome. The induced double-strand breaks are repaired through nonhomologous end-joining (NHEJ) or homologous recombination (HR), resulting in targeted mutations.

    Webinars

    • APR 18, 2024 | 7:00 AM
      Beyond CRISPR Basics: Molecular Biology Innovations in Cell Engineering
      Beyond CRISPR Basics: Molecular Biology Innovations in Cell Engineering
      Abstract: Beginning with a brief historical overview of CRISPR, we will trace its evolution to the current state of gene engineering, highlighting its pivotal role in reshaping the landscape...
      Speaker: Travis Hardcastle
      Sponsored By: Thermo Fisher Scientific
      24
      DEC 05, 2023 | 8:00 AM
      CGX10 Cell Isolation System:
      CGX10 Cell Isolation System:
      CGX10 Cell Isolation System: Introduction, Utility, and Assessment in a GMP-grade Environment for Multiparametric Cell Sorting A future of long-term, minimally toxic immunotherapy personaliz...
      Speaker: Jerry Barnhart , Manoja Eswara
      Sponsored By: Sony Biotechnology
      13
      OCT 31, 2023 | 11:00 AM
      Optimizing Experimental Design for Gene Editing Success: tips and tricks to increase efficiency and improve outcomes
      Optimizing Experimental Design for Gene Editing Success: tips...
      With the promise of targeted gene editing and CRISPR technologies comes increasing experimental complexity and design challenges. Success in gene editing experiments may depend on many varia...
      Speaker: Fuqiang Chen, Ph.D.
      Sponsored By: MilliporeSigma
      8
      OCT 24, 2023 | 9:00 PM
      Protein Expression Webinar
      Protein Expression Webinar
      This webinar is hosted by Thermo Fisher Scientific in collaboration with the Walter and Eliza Hall Institute of Medical Research (WEHI). The webinar aims to demonstrate the benefits of the E...
      Speaker: Marija Dramicanin, PhD , Roland Leathers, PhD
      Sponsored By: Thermo Fisher Scientific
      15
      SEP 26, 2023 | 8:00 AM
      Exploring Extracellular Vesicles: Unlocking the Potential of EV Research
      Exploring Extracellular Vesicles: Unlocking the Potential of EV...
      Join us for an educational webinar that delves into the fascinating world of Extracellular Vesicles (EVs) and their impact on biomedical research and medicine. In collaboration with ExoVecto...
      Speaker: Roland Leathers, PhD , Jeroen de Vrij, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      41 1
      SEP 13, 2023 | 7:00 AM
      Developing genotyping platforms to enable discovery, quality control and genomic breeding at CoverCress Inc.
      Developing genotyping platforms to enable discovery, quality control...
      As the demand for renewal fuel feedstocks continues to grow, non-food feedstocks production must significantly increase to meet demand. Winter oilseeds grown in cooler climates provide oppor...
      Speaker: Ratan Chopra, PhD
      Sponsored By: LGC Biosearch Technologies
      17
      JUL 26, 2023 | 4:45 PM
      SLEEK: A highly efficient transgene knock-in technology in clinically relevant cell types
      SLEEK: A highly efficient transgene knock-in technology in clinically...
      Inefficient knock-in of transgene cargos limits the potential of cell-based medicines. In this study, we used a CRISPR nuclease that targets a site within an exon of an essential gene and de...
      Speaker: Dr. John Zuris
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      5
      JUL 26, 2023 | 3:10 PM
      Harnessing iNKT Cells for "Off-The-Shelf" Cancer Therapy
      Harnessing iNKT Cells for "Off-The-Shelf" Cancer Therapy
      Cell-based immunotherapy has become the new-generation cancer medicine, and “off-the-shelf” cell products that can be manufactured at large scale and distributed readily to treat...
      Speaker: Dr. Lili Yang
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      JUL 26, 2023 | 2:30 PM
      Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
      Serine-129 phosphorylation of α-synuclein is an activity-dependent...
      Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
      Speaker: Dr. Leonardo Parra-Rivas
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      JUL 26, 2023 | 11:20 AM
      CD3ζ as a novel integration site for reprogramming immune cells with Chimeric Antigen Receptors
      CD3ζ as a novel integration site for reprogramming immune cells...
      Chimeric antigen receptor (CAR)-reprogrammed immune cells offer exciting therapeutic potential for addressing oncology, autoimmune diseases, transplant medicine, and infections. However, cur...
      Speaker: Dr. Dimitrios L. Wagner
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      JUN 15, 2023 | 10:00 AM
      Expanding the frontiers of gene editing: the role of genotypic confirmation
      Expanding the frontiers of gene editing: the role of genotypic...
      Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      18
      JUN 14, 2023 | 8:00 AM
      Expanding the frontiers of gene editing: the role of genotypic confirmation
      Expanding the frontiers of gene editing: the role of genotypic...
      Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      15
      MAR 28, 2023 | 3:30 AM
      Biofluid-based biomarkers for neurological disease
      Biofluid-based biomarkers for neurological disease
      Date: March 28, 2023 Time: 3:30am (PDT), 6:30am (EDT), 12:30pm (CEST) Biofluid-based neurological biomarkers have shown promise in helping to improve diagnostic accuracy, predict disease pro...
      Speaker: Steffen Halbgebauer, PhD , Dr. Hayrettin Tumani , Yoav Noam, PhD
      Sponsored By: Bio-Techne
      20
      MAR 08, 2023 | 8:00 AM
      Considerations to Limit Off-Target Edits in your Gene Editing Experiments
      Considerations to Limit Off-Target Edits in your Gene Editing...
      Date: March 08, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Engineered nucleases like the CRISPR-Cas9 system provide researchers with powerful tools for the manipulation of the geno...
      Speaker: Kevin Pridham
      Sponsored By: Thermo Fisher Scientific
      12
      FEB 02, 2023 | 11:00 AM
      Break the Bottleneck: Automate Plasmid Maxi-prep with AmMagâ„¢ Quatro
      Break the Bottleneck: Automate Plasmid Maxi-prep with AmMagâ„¢ Quatro
      Date: December 13, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CEST) Plasmid DNA (pDNA) is an essential component of molecular biotechnology applications, such as protein expression and...
      Speaker: Rouba Najjar, MBA
      Sponsored By: GenScript
      11 1
      DEC 07, 2022 | 9:00 AM
      Gibco Cell Culture Heroes: 60th Anniversary Edition
      Gibco Cell Culture Heroes: 60th Anniversary Edition
      Date: December 07, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Join us for an exciting live panel webinar, as we celebrate the 60th anniversary of Gibco Cell Culture. The panelists...
      Speaker: Jessica Hess , Rukia Henry , Ernesto Goulart , Ameet Chimote, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      20
      NOV 16, 2022 | 7:00 PM
      Innovation in Science and Technology: Translating Cellular Therapies from Bench to Bedside
      Innovation in Science and Technology: Translating Cellular Therapies...
      Date: November 16, 2022 Time: 2:00pm (AEST) Date: November 17, 2022 7:00pm (PST), 10:00pm (EST), 4:00am (CET) The growth in FDA-approved cell and gene therapy products for the treatment of d...
      Speaker: Khalid Shah , Jean Qiu
      Sponsored By: Revvity
      26
      OCT 19, 2022 | 12:00 PM
      Keynote Presentation: Advancing Toward Recovery from Post-Acute Sequelae of SARS-CoV-2 Infection (PASC): The NIH RECOVER Initiative with Live Q&A
      Keynote Presentation: Advancing Toward Recovery from Post-Acute...
      The COVID-19 pandemic has affected the lives of most Americans. The consequences on the future health of the nation are unknown but likely profound. Well known is the condition known in the...
      Speaker: Walter Koroshetz, MD
      Presented at: Coronavirus Series
      4
      OCT 06, 2022 | 5:00 PM
      Driving genetic biomarker discovery for detecting and monitoring tumor pathogenesis
      Driving genetic biomarker discovery for detecting and monitoring...
      Genetic biomarkers have become increasingly important for disease prediction, early disease detection and progression, and options for intervention. Tumor biopsies are commonly used as sourc...
      Speaker: Dr. Archana Gupta
      Sponsored By: Thermo Fisher Scientific
      11
      OCT 05, 2022 | 9:00 PM
      Genome editing: Disease modelling to novel therapeutics
      Genome editing: Disease modelling to novel therapeutics
      Date: October 6, 2022 Time: Time: 9:30am IST, 12:00pm SGT, 1:00pm JST, KThe discovery of the CRISPR/Cas9 system has transformed research and now allows straightforward alterations in the geno...
      Speaker: Erik Willems, PhD , Jason Potter, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      23 2
      OCT 04, 2022 | 7:00 AM
      Tools & Strategies for Implementing iPSC-based Cell Models for Neurodegenerative Disease Drug Discovery
      Tools & Strategies for Implementing iPSC-based Cell Models for...
      Date: October 04, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) The ability to derive induced pluripotent stem cells (iPSCs) from differentiated cell types such as fibroblasts, has r...
      Speaker: Benjamin Schmid , Peter Reinhardt
      Sponsored By: Bioneer A/S
      13
      SEP 28, 2022 | 7:00 AM
      From Bench to Bedside: Targeted Gene Editing
      From Bench to Bedside: Targeted Gene Editing
      Date: September 28, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) CRISPR/Cas gene editing technology has rapidly evolved over the last decade. Its versatility extends from creating t...
      Speaker: Jennifer Bennett, PhD
      Sponsored By: MilliporeSigma
      20
      SEP 27, 2022 | 8:00 AM
      Efficient and Rapid Discovery of Novel Temperature Sensitive Alleles with the Onyx® Digital Genome Engineering Platform
      Efficient and Rapid Discovery of Novel Temperature Sensitive Alleles...
      Date: September 27, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Temperature sensitive (TS) alleles are mutations in essential genes that allow for growth at permissive temperatures...
      Speaker: Randy Lacey
      Sponsored By: Inscripta
      10 2
      SEP 22, 2022 | 9:00 AM
      Human proteomics: from the operating room to the lab and back
      Human proteomics: from the operating room to the lab and back
      Date: September 22, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Optimizing platforms for surgical specimen collection and deep human phenotyping was used to enhance protein biomarke...
      Speaker: Vinit Mahajan M.D., Ph.D.
      Sponsored By: SomaLogic
      17
    APR 18, 2024 | 7:00 AM
    Beyond CRISPR Basics: Molecular Biology Innovations in Cell Engineering
    Beyond CRISPR Basics: Molecular Biology Innovations in Cell Engineering
    Abstract: Beginning with a brief historical overview of CRISPR, we will trace its evolution to the current state of gene engineering, highlighting its pivotal role in reshaping the landscape...
    Speaker: Travis Hardcastle
    Sponsored By: Thermo Fisher Scientific
    24
    DEC 05, 2023 | 8:00 AM
    CGX10 Cell Isolation System:
    CGX10 Cell Isolation System:
    CGX10 Cell Isolation System: Introduction, Utility, and Assessment in a GMP-grade Environment for Multiparametric Cell Sorting A future of long-term, minimally toxic immunotherapy personaliz...
    Speaker: Jerry Barnhart , Manoja Eswara
    Sponsored By: Sony Biotechnology
    13
    OCT 31, 2023 | 11:00 AM
    Optimizing Experimental Design for Gene Editing Success: tips and tricks to increase efficiency and improve outcomes
    Optimizing Experimental Design for Gene Editing Success: tips...
    With the promise of targeted gene editing and CRISPR technologies comes increasing experimental complexity and design challenges. Success in gene editing experiments may depend on many varia...
    Speaker: Fuqiang Chen, Ph.D.
    Sponsored By: MilliporeSigma
    8
    OCT 24, 2023 | 9:00 PM
    Protein Expression Webinar
    Protein Expression Webinar
    This webinar is hosted by Thermo Fisher Scientific in collaboration with the Walter and Eliza Hall Institute of Medical Research (WEHI). The webinar aims to demonstrate the benefits of the E...
    Speaker: Marija Dramicanin, PhD , Roland Leathers, PhD
    Sponsored By: Thermo Fisher Scientific
    15
    SEP 26, 2023 | 8:00 AM
    Exploring Extracellular Vesicles: Unlocking the Potential of EV Research
    Exploring Extracellular Vesicles: Unlocking the Potential of EV...
    Join us for an educational webinar that delves into the fascinating world of Extracellular Vesicles (EVs) and their impact on biomedical research and medicine. In collaboration with ExoVecto...
    Speaker: Roland Leathers, PhD , Jeroen de Vrij, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    41 1
     
     
  • SEP 13, 2023 | 7:00 AM
    Developing genotyping platforms to enable discovery, quality control and genomic breeding at CoverCress Inc.
    Developing genotyping platforms to enable discovery, quality control...
    As the demand for renewal fuel feedstocks continues to grow, non-food feedstocks production must significantly increase to meet demand. Winter oilseeds grown in cooler climates provide oppor...
    Speaker: Ratan Chopra, PhD
    Sponsored By: LGC Biosearch Technologies
    17
    JUL 26, 2023 | 4:45 PM
    SLEEK: A highly efficient transgene knock-in technology in clinically relevant cell types
    SLEEK: A highly efficient transgene knock-in technology in clinically...
    Inefficient knock-in of transgene cargos limits the potential of cell-based medicines. In this study, we used a CRISPR nuclease that targets a site within an exon of an essential gene and de...
    Speaker: Dr. John Zuris
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    5
    JUL 26, 2023 | 3:10 PM
    Harnessing iNKT Cells for "Off-The-Shelf" Cancer Therapy
    Harnessing iNKT Cells for "Off-The-Shelf" Cancer Therapy
    Cell-based immunotherapy has become the new-generation cancer medicine, and “off-the-shelf” cell products that can be manufactured at large scale and distributed readily to treat...
    Speaker: Dr. Lili Yang
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
    JUL 26, 2023 | 2:30 PM
    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
    Serine-129 phosphorylation of α-synuclein is an activity-dependent...
    Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states,...
    Speaker: Dr. Leonardo Parra-Rivas
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
    JUL 26, 2023 | 11:20 AM
    CD3ζ as a novel integration site for reprogramming immune cells with Chimeric Antigen Receptors
    CD3ζ as a novel integration site for reprogramming immune cells...
    Chimeric antigen receptor (CAR)-reprogrammed immune cells offer exciting therapeutic potential for addressing oncology, autoimmune diseases, transplant medicine, and infections. However, cur...
    Speaker: Dr. Dimitrios L. Wagner
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
     
     
  • JUN 15, 2023 | 10:00 AM
    Expanding the frontiers of gene editing: the role of genotypic confirmation
    Expanding the frontiers of gene editing: the role of genotypic...
    Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    18
    JUN 14, 2023 | 8:00 AM
    Expanding the frontiers of gene editing: the role of genotypic confirmation
    Expanding the frontiers of gene editing: the role of genotypic...
    Insights gained from studies using genome editing tools can provide a better understanding of cellular physiology, so that we can uncover answers to complex diseases and ultimately develop t...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    15
    MAR 28, 2023 | 3:30 AM
    Biofluid-based biomarkers for neurological disease
    Biofluid-based biomarkers for neurological disease
    Date: March 28, 2023 Time: 3:30am (PDT), 6:30am (EDT), 12:30pm (CEST) Biofluid-based neurological biomarkers have shown promise in helping to improve diagnostic accuracy, predict disease pro...
    Speaker: Steffen Halbgebauer, PhD , Dr. Hayrettin Tumani , Yoav Noam, PhD
    Sponsored By: Bio-Techne
    20
    MAR 08, 2023 | 8:00 AM
    Considerations to Limit Off-Target Edits in your Gene Editing Experiments
    Considerations to Limit Off-Target Edits in your Gene Editing...
    Date: March 08, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Engineered nucleases like the CRISPR-Cas9 system provide researchers with powerful tools for the manipulation of the geno...
    Speaker: Kevin Pridham
    Sponsored By: Thermo Fisher Scientific
    12
    FEB 02, 2023 | 11:00 AM
    Break the Bottleneck: Automate Plasmid Maxi-prep with AmMagâ„¢ Quatro
    Break the Bottleneck: Automate Plasmid Maxi-prep with AmMagâ„¢ Quatro
    Date: December 13, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CEST) Plasmid DNA (pDNA) is an essential component of molecular biotechnology applications, such as protein expression and...
    Speaker: Rouba Najjar, MBA
    Sponsored By: GenScript
    11 1
     
     
  • DEC 07, 2022 | 9:00 AM
    Gibco Cell Culture Heroes: 60th Anniversary Edition
    Gibco Cell Culture Heroes: 60th Anniversary Edition
    Date: December 07, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Join us for an exciting live panel webinar, as we celebrate the 60th anniversary of Gibco Cell Culture. The panelists...
    Speaker: Jessica Hess , Rukia Henry , Ernesto Goulart , Ameet Chimote, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    20
    NOV 16, 2022 | 7:00 PM
    Innovation in Science and Technology: Translating Cellular Therapies from Bench to Bedside
    Innovation in Science and Technology: Translating Cellular Therapies...
    Date: November 16, 2022 Time: 2:00pm (AEST) Date: November 17, 2022 7:00pm (PST), 10:00pm (EST), 4:00am (CET) The growth in FDA-approved cell and gene therapy products for the treatment of d...
    Speaker: Khalid Shah , Jean Qiu
    Sponsored By: Revvity
    26
    OCT 19, 2022 | 12:00 PM
    Keynote Presentation: Advancing Toward Recovery from Post-Acute Sequelae of SARS-CoV-2 Infection (PASC): The NIH RECOVER Initiative with Live Q&A
    Keynote Presentation: Advancing Toward Recovery from Post-Acute...
    The COVID-19 pandemic has affected the lives of most Americans. The consequences on the future health of the nation are unknown but likely profound. Well known is the condition known in the...
    Speaker: Walter Koroshetz, MD
    Presented at: Coronavirus Series
    4
    OCT 06, 2022 | 5:00 PM
    Driving genetic biomarker discovery for detecting and monitoring tumor pathogenesis
    Driving genetic biomarker discovery for detecting and monitoring...
    Genetic biomarkers have become increasingly important for disease prediction, early disease detection and progression, and options for intervention. Tumor biopsies are commonly used as sourc...
    Speaker: Dr. Archana Gupta
    Sponsored By: Thermo Fisher Scientific
    11
    OCT 05, 2022 | 9:00 PM
    Genome editing: Disease modelling to novel therapeutics
    Genome editing: Disease modelling to novel therapeutics
    Date: October 6, 2022 Time: Time: 9:30am IST, 12:00pm SGT, 1:00pm JST, KThe discovery of the CRISPR/Cas9 system has transformed research and now allows straightforward alterations in the geno...
    Speaker: Erik Willems, PhD , Jason Potter, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    23 2
     
     
  • OCT 04, 2022 | 7:00 AM
    Tools & Strategies for Implementing iPSC-based Cell Models for Neurodegenerative Disease Drug Discovery
    Tools & Strategies for Implementing iPSC-based Cell Models for...
    Date: October 04, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) The ability to derive induced pluripotent stem cells (iPSCs) from differentiated cell types such as fibroblasts, has r...
    Speaker: Benjamin Schmid , Peter Reinhardt
    Sponsored By: Bioneer A/S
    13
    SEP 28, 2022 | 7:00 AM
    From Bench to Bedside: Targeted Gene Editing
    From Bench to Bedside: Targeted Gene Editing
    Date: September 28, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) CRISPR/Cas gene editing technology has rapidly evolved over the last decade. Its versatility extends from creating t...
    Speaker: Jennifer Bennett, PhD
    Sponsored By: MilliporeSigma
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    SEP 27, 2022 | 8:00 AM
    Efficient and Rapid Discovery of Novel Temperature Sensitive Alleles with the Onyx® Digital Genome Engineering Platform
    Efficient and Rapid Discovery of Novel Temperature Sensitive Alleles...
    Date: September 27, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Temperature sensitive (TS) alleles are mutations in essential genes that allow for growth at permissive temperatures...
    Speaker: Randy Lacey
    Sponsored By: Inscripta
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    SEP 22, 2022 | 9:00 AM
    Human proteomics: from the operating room to the lab and back
    Human proteomics: from the operating room to the lab and back
    Date: September 22, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Optimizing platforms for surgical specimen collection and deep human phenotyping was used to enhance protein biomarke...
    Speaker: Vinit Mahajan M.D., Ph.D.
    Sponsored By: SomaLogic
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