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    Gene Editing

    Gene Editing: a type of genetic engineering in which DNA is inserted, deleted or replaced in the genome of a living organism using engineered nucleases, or "molecular scissors". These nucleases create site-specific double-strand breaks (DSBs) at desired locations in the genome. The induced double-strand breaks are repaired through nonhomologous end-joining (NHEJ) or homologous recombination (HR), resulting in targeted mutations.

    Webinars

    • SEP 20, 2022 | 9:00 AM
      Breaking through RT-qPCR boundaries in gene expression analysis
      Breaking through RT-qPCR boundaries in gene expression analysis
      Date: September 20, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Variation in gene expression among cell types, tissues, and organisms is commonly examined by reverse transcription...
      Speaker: Jennifer Sandoval, M.S.
      Sponsored By: Thermo Fisher Scientific
      28
      SEP 14, 2022 | 8:00 AM
      Integrating spatial resolution into flow cytometric analysis
      Integrating spatial resolution into flow cytometric analysis
      Date: September 14, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) In this session, the benefits of combining in-line high speed imaging with flow cytometry will be explored. Acoustic...
      Speaker: Heaven Roberts, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      13
      JUN 22, 2022 | 8:00 AM
      Effective application of targeted sequence analysis to propel the biopharmaceutic development continuum from pre-clinical research and biomarker discovery through manufacturing
      Effective application of targeted sequence analysis to propel...
      Biopharmaceutical discovery, development and manufacturing requires the use of genetic analysis across the development continuum. Sanger sequencing and fragment analysis by capillary electro...
      Speaker: Edgar Schreiber, PhD
      Sponsored By: Thermo Fisher Scientific
      9 2
      JUN 02, 2022 | 8:00 AM
      From pathogen identification to disease prevention and cure: understanding how Sanger sequencing and fragment analysis is powering infectious disease research today
      From pathogen identification to disease prevention and cure: understanding...
      Infectious diseases present a great challenge to global health and its economy. The 2020 SARS- CoV-2 pandemic highlighted the importance of rapid identification, characterization and surveil...
      Speaker: Dr. Archana Gupta
      Sponsored By: Thermo Fisher Scientific
      16
      MAY 03, 2022 | 8:00 AM
      Unlocking the genomics of cancer using Sanger sequencing and fragment analysis
      Unlocking the genomics of cancer using Sanger sequencing and fragment...
      Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      15
      APR 05, 2022 | 8:00 AM
      Investigating antimicrobial mechanisms-of-action using automated genome-wide and gene-specific editing
      Investigating antimicrobial mechanisms-of-action using automated...
      Date: April 05, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEDT) Members of the cinnamic acid and stilbenoid chemical families are common intermediates in the production of important bi...
      Speaker: Ali Clark-ElSayed
      Sponsored By: Inscripta
      8
      FEB 23, 2022 | 3:00 PM
      Genetically Engineered Custom Cell Lines for Pre-Clinical Research and Biomanufacturing
      Genetically Engineered Custom Cell Lines for Pre-Clinical Research...
      Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
      Speaker: Stacey Ward, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2022
      Sponsored By: MilliporeSigma
      1
      FEB 01, 2022 | 8:00 AM
      Iterative Genome Engineering for Rapid Improvement of Protein Activity and Production
      Iterative Genome Engineering for Rapid Improvement of Protein...
      Date: February 01, 2021 Time: 08:00am (PST), 11:00am (EST) The Design–Generate–Test–Learn (DGTL) cycle represents an efficient approach to biological engineering, from sing...
      Speaker: Eric Abbate
      Sponsored By: Inscripta
      13 1
      DEC 09, 2021 | 8:00 AM
      Reprogramming human regulatory T cell specificity with a novel anti-HLA-A2 chimeric antigen receptor
      Reprogramming human regulatory T cell specificity with a novel...
      Date: December 9, 2021 Time: 8:00am (PDT), 11:00am (EDT) Engineering human regulatory T cells (Tregs) with a chimeric antigen receptor (CAR) targeting donorderived human leukocyte antigen (H...
      Speaker: Leonardo Ferreira
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      NOV 30, 2021 | 8:00 AM
      ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR T Cell Manufacturing with nS/MARt Vectors
      ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR...
      Date: November 30, 2021 Time: 8:00am (PDT), 11:00am (EDT) The DNA Vector Lab at the German Cancer Research Center (DKFZ) has developed Nano-S/MARt (nS/MARt), a novel DNA Vector platform that...
      Speaker: Matthias Bozza
      Sponsored By: MaxCyte®
      5
      NOV 17, 2021 | 7:00 AM
      CRISPR-based transcriptional activation tools for silent genes in filamentous fungi
      CRISPR-based transcriptional activation tools for silent genes...
      DATE: November 17, 2021 TIME: 7:00am PST, 10:00am EST, 4:00pm CET Filamentous fungi are historically known to be a rich reservoir of bioactive compounds that are applied in a myriad of field...
      Speaker: Laszlo Mozsik
      Sponsored By: GenScript
      13 2
      OCT 14, 2021 | 9:00 AM
      Session 3: Simple steps to publication-quality western blots
      Session 3: Simple steps to publication-quality western blots
      Date: October 14, 2021 Time: 9:00am (PDT), 12:00pm (EDT), 5:00pm GMT Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring spe...
      Speaker: Kelli Feather-Henigan
      Presented at: Webinar series: Simple steps to publication-quality western blots
      Sponsored By: Thermo Fisher Scientific
      28
      OCT 14, 2021 | 7:00 AM
      Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
      Heterologous Protein Engineering and characterization of native...
      Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
      Speaker: Tyson Shepherd, PhD
      Sponsored By: Inscripta
      22
      OCT 13, 2021 | 7:00 AM
      Session 2: Simple steps to publication-quality western blots
      Session 2: Simple steps to publication-quality western blots
      Date: October 13, 2021 Time: 7:00am (PDT), 10:00am (EDT) Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring specific target...
      Speaker: Caleb Shearrow
      Presented at: Webinar series: Simple steps to publication-quality western blots
      Sponsored By: Thermo Fisher Scientific
      31 1
      OCT 12, 2021 | 5:00 PM
      Session 1: Simple steps to publication-quality western blots
      Session 1: Simple steps to publication-quality western blots
      Date: October 12, 2021 Time: 5:00pm (PDT), 8:00pm (EDT) 222 Learning Objectives 222 222 222 Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved...
      Speaker: Jordan Thompson, PhD
      Presented at: Webinar series: Simple steps to publication-quality western blots
      Sponsored By: Thermo Fisher Scientific
      39 1
      OCT 12, 2021 | 8:00 AM
      The growing concern of off-target effects: How to measure and minimize off-target effects in your genome editing experiments.
      The growing concern of off-target effects: How to measure and...
      Date: October 12, 2021 Time: 8:00am (PDT), 11:00am (EDT) CRISPR-Cas9 is a nuclease-based genome editing system which has seen exponential growth in adoption with broad applications from basi...
      Speaker: Pandhita Pochanard
      Sponsored By: Thermo Fisher Scientific/Gibco
      30
      OCT 07, 2021 | 7:00 AM
      Troubleshooting Cell-based Assays - Ask the Experts to Avoid Common Pitfalls from Cell Seeding to Analysis
      Troubleshooting Cell-based Assays - Ask the Experts to Avoid Common...
      DATE: October 7, 2021 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
      Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
      Sponsored By: Eppendorf, Promega
      12
      SEP 29, 2021 | 11:59 PM
      Nanoparticle Based Delivery of Gene Editing Enzymes
      Nanoparticle Based Delivery of Gene Editing Enzymes
      Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
      Speaker: Niren Murthy, PhD
      Presented at: CRISPR Virtual Event Series 2021
      2 2
      SEP 29, 2021 | 12:00 PM
      How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
      How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
      Over the past ten years, CRISPR technology has revolutionized genome engineering, as reflected by the recently awarded Nobel Prize. Nevertheless, the process of performing and characterizing...
      Speaker: Domenica Martorana, PhD
      Presented at: CRISPR Virtual Event Series 2021
      Sponsored By: QIAGEN
      1
      SEP 29, 2021 | 9:00 AM
      Panel Presentation: Harnessing Novel CRISPR Systems for Transcriptome Engineering
      Panel Presentation: Harnessing Novel CRISPR Systems for Transcriptome...
      RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 and novel RNA targeti...
      Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
      Presented at: CRISPR Virtual Event Series 2021
      1
      SEP 22, 2021 | 7:30 AM
      Panel Presentation: Concept-to-Commercialization: Thermo Fisher's Unique Approach to Rapidly Advancing Your Antibody and Protein Therapeutics
      Panel Presentation: Concept-to-Commercialization: Thermo Fisher's...
      Date: September 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. T...
      Speaker: Jeff Hou, PhD , Steve Lewis
      Presented at: Cell Biology Virtual Event Series 2021
      Sponsored By: Thermo Fisher Scientific
      0
      SEP 17, 2021 | 12:00 PM
      Developing better techniques for 3D culture and analysis.
      Developing better techniques for 3D culture and analysis.
      Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
      Speaker: Edwin Golez, M.S. , Bhaskar Mandavilli
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 2
      SEP 16, 2021 | 8:00 AM
      Concept-to-Commercialization: Thermo Fisher's unique approach to rapidly advancing your antibody and protein therapeutics
      Concept-to-Commercialization: Thermo Fisher's unique approach...
      Date: September 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. T...
      Speaker: Jeff Hou, PhD , Steve Lewis
      Sponsored By: Thermo Fisher Scientific
      1
      SEP 14, 2021 | 7:00 AM
      What prevents you from increasing your PCR productivity?
      What prevents you from increasing your PCR productivity?
      Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
      Speaker: Arora Phang, PhD
      Sponsored By: Eppendorf
      24 1
    SEP 20, 2022 | 9:00 AM
    Breaking through RT-qPCR boundaries in gene expression analysis
    Breaking through RT-qPCR boundaries in gene expression analysis
    Date: September 20, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Variation in gene expression among cell types, tissues, and organisms is commonly examined by reverse transcription...
    Speaker: Jennifer Sandoval, M.S.
    Sponsored By: Thermo Fisher Scientific
    28
    SEP 14, 2022 | 8:00 AM
    Integrating spatial resolution into flow cytometric analysis
    Integrating spatial resolution into flow cytometric analysis
    Date: September 14, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) In this session, the benefits of combining in-line high speed imaging with flow cytometry will be explored. Acoustic...
    Speaker: Heaven Roberts, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    13
    JUN 22, 2022 | 8:00 AM
    Effective application of targeted sequence analysis to propel the biopharmaceutic development continuum from pre-clinical research and biomarker discovery through manufacturing
    Effective application of targeted sequence analysis to propel...
    Biopharmaceutical discovery, development and manufacturing requires the use of genetic analysis across the development continuum. Sanger sequencing and fragment analysis by capillary electro...
    Speaker: Edgar Schreiber, PhD
    Sponsored By: Thermo Fisher Scientific
    9 2
    JUN 02, 2022 | 8:00 AM
    From pathogen identification to disease prevention and cure: understanding how Sanger sequencing and fragment analysis is powering infectious disease research today
    From pathogen identification to disease prevention and cure: understanding...
    Infectious diseases present a great challenge to global health and its economy. The 2020 SARS- CoV-2 pandemic highlighted the importance of rapid identification, characterization and surveil...
    Speaker: Dr. Archana Gupta
    Sponsored By: Thermo Fisher Scientific
    16
    MAY 03, 2022 | 8:00 AM
    Unlocking the genomics of cancer using Sanger sequencing and fragment analysis
    Unlocking the genomics of cancer using Sanger sequencing and fragment...
    Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    15
     
     
  • APR 05, 2022 | 8:00 AM
    Investigating antimicrobial mechanisms-of-action using automated genome-wide and gene-specific editing
    Investigating antimicrobial mechanisms-of-action using automated...
    Date: April 05, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEDT) Members of the cinnamic acid and stilbenoid chemical families are common intermediates in the production of important bi...
    Speaker: Ali Clark-ElSayed
    Sponsored By: Inscripta
    8
    FEB 23, 2022 | 3:00 PM
    Genetically Engineered Custom Cell Lines for Pre-Clinical Research and Biomanufacturing
    Genetically Engineered Custom Cell Lines for Pre-Clinical Research...
    Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
    Speaker: Stacey Ward, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2022
    Sponsored By: MilliporeSigma
    1
    FEB 01, 2022 | 8:00 AM
    Iterative Genome Engineering for Rapid Improvement of Protein Activity and Production
    Iterative Genome Engineering for Rapid Improvement of Protein...
    Date: February 01, 2021 Time: 08:00am (PST), 11:00am (EST) The Design–Generate–Test–Learn (DGTL) cycle represents an efficient approach to biological engineering, from sing...
    Speaker: Eric Abbate
    Sponsored By: Inscripta
    13 1
    DEC 09, 2021 | 8:00 AM
    Reprogramming human regulatory T cell specificity with a novel anti-HLA-A2 chimeric antigen receptor
    Reprogramming human regulatory T cell specificity with a novel...
    Date: December 9, 2021 Time: 8:00am (PDT), 11:00am (EDT) Engineering human regulatory T cells (Tregs) with a chimeric antigen receptor (CAR) targeting donorderived human leukocyte antigen (H...
    Speaker: Leonardo Ferreira
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    NOV 30, 2021 | 8:00 AM
    ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR T Cell Manufacturing with nS/MARt Vectors
    ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR...
    Date: November 30, 2021 Time: 8:00am (PDT), 11:00am (EDT) The DNA Vector Lab at the German Cancer Research Center (DKFZ) has developed Nano-S/MARt (nS/MARt), a novel DNA Vector platform that...
    Speaker: Matthias Bozza
    Sponsored By: MaxCyte®
    5
     
     
  • NOV 17, 2021 | 7:00 AM
    CRISPR-based transcriptional activation tools for silent genes in filamentous fungi
    CRISPR-based transcriptional activation tools for silent genes...
    DATE: November 17, 2021 TIME: 7:00am PST, 10:00am EST, 4:00pm CET Filamentous fungi are historically known to be a rich reservoir of bioactive compounds that are applied in a myriad of field...
    Speaker: Laszlo Mozsik
    Sponsored By: GenScript
    13 2
    OCT 14, 2021 | 9:00 AM
    Session 3: Simple steps to publication-quality western blots
    Session 3: Simple steps to publication-quality western blots
    Date: October 14, 2021 Time: 9:00am (PDT), 12:00pm (EDT), 5:00pm GMT Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring spe...
    Speaker: Kelli Feather-Henigan
    Presented at: Webinar series: Simple steps to publication-quality western blots
    Sponsored By: Thermo Fisher Scientific
    28
    OCT 14, 2021 | 7:00 AM
    Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
    Heterologous Protein Engineering and characterization of native...
    Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
    Speaker: Tyson Shepherd, PhD
    Sponsored By: Inscripta
    22
    OCT 13, 2021 | 7:00 AM
    Session 2: Simple steps to publication-quality western blots
    Session 2: Simple steps to publication-quality western blots
    Date: October 13, 2021 Time: 7:00am (PDT), 10:00am (EDT) Western blot analysis is a method widely used in the lab today because of its versatility in detecting and measuring specific target...
    Speaker: Caleb Shearrow
    Presented at: Webinar series: Simple steps to publication-quality western blots
    Sponsored By: Thermo Fisher Scientific
    31 1
    OCT 12, 2021 | 5:00 PM
    Session 1: Simple steps to publication-quality western blots
    Session 1: Simple steps to publication-quality western blots
    Date: October 12, 2021 Time: 5:00pm (PDT), 8:00pm (EDT) 222 Learning Objectives 222 222 222 Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved...
    Speaker: Jordan Thompson, PhD
    Presented at: Webinar series: Simple steps to publication-quality western blots
    Sponsored By: Thermo Fisher Scientific
    39 1
     
     
  • OCT 12, 2021 | 8:00 AM
    The growing concern of off-target effects: How to measure and minimize off-target effects in your genome editing experiments.
    The growing concern of off-target effects: How to measure and...
    Date: October 12, 2021 Time: 8:00am (PDT), 11:00am (EDT) CRISPR-Cas9 is a nuclease-based genome editing system which has seen exponential growth in adoption with broad applications from basi...
    Speaker: Pandhita Pochanard
    Sponsored By: Thermo Fisher Scientific/Gibco
    30
    OCT 07, 2021 | 7:00 AM
    Troubleshooting Cell-based Assays - Ask the Experts to Avoid Common Pitfalls from Cell Seeding to Analysis
    Troubleshooting Cell-based Assays - Ask the Experts to Avoid Common...
    DATE: October 7, 2021 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
    Speaker: Jessica Wagener, PhD , Erik Bonke, PhD
    Sponsored By: Eppendorf, Promega
    12
    SEP 29, 2021 | 11:59 PM
    Nanoparticle Based Delivery of Gene Editing Enzymes
    Nanoparticle Based Delivery of Gene Editing Enzymes
    Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
    Speaker: Niren Murthy, PhD
    Presented at: CRISPR Virtual Event Series 2021
    2 2
    SEP 29, 2021 | 12:00 PM
    How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
    How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
    Over the past ten years, CRISPR technology has revolutionized genome engineering, as reflected by the recently awarded Nobel Prize. Nevertheless, the process of performing and characterizing...
    Speaker: Domenica Martorana, PhD
    Presented at: CRISPR Virtual Event Series 2021
    Sponsored By: QIAGEN
    1
    SEP 29, 2021 | 9:00 AM
    Panel Presentation: Harnessing Novel CRISPR Systems for Transcriptome Engineering
    Panel Presentation: Harnessing Novel CRISPR Systems for Transcriptome...
    RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. We demonstrate that RNA-targeting CRISPR effector Cas13 and novel RNA targeti...
    Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
    Presented at: CRISPR Virtual Event Series 2021
    1
     
     
  • SEP 22, 2021 | 7:30 AM
    Panel Presentation: Concept-to-Commercialization: Thermo Fisher's Unique Approach to Rapidly Advancing Your Antibody and Protein Therapeutics
    Panel Presentation: Concept-to-Commercialization: Thermo Fisher's...
    Date: September 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. T...
    Speaker: Jeff Hou, PhD , Steve Lewis
    Presented at: Cell Biology Virtual Event Series 2021
    Sponsored By: Thermo Fisher Scientific
    0
    SEP 17, 2021 | 12:00 PM
    Developing better techniques for 3D culture and analysis.
    Developing better techniques for 3D culture and analysis.
    Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
    Speaker: Edwin Golez, M.S. , Bhaskar Mandavilli
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 2
    SEP 16, 2021 | 8:00 AM
    Concept-to-Commercialization: Thermo Fisher's unique approach to rapidly advancing your antibody and protein therapeutics
    Concept-to-Commercialization: Thermo Fisher's unique approach...
    Date: September 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. T...
    Speaker: Jeff Hou, PhD , Steve Lewis
    Sponsored By: Thermo Fisher Scientific
    1
    SEP 14, 2021 | 7:00 AM
    What prevents you from increasing your PCR productivity?
    What prevents you from increasing your PCR productivity?
    Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
    Speaker: Arora Phang, PhD
    Sponsored By: Eppendorf
    24 1
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