Genetics: the study of genes, genetic variation, and heredity in living organisms. It is generally considered a field of biology, but intersects frequently with many other life sciences and is strongly linked with the study of information systems. The father of genetics is Gregor Mendel, a late 19th-century scientist and Augustinian friar. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene.
In this talk, I will use examples from my research using big data analytics to define ideals of precision medicine and digital health across a variety of diseases. Specifically, I will i...
Challenges in achieving comparability, reproducibility and accuracy in biological assays has driven a demand for improved confidence in measurements that support development of regenerative m...
Identification of the many complex genetic aberrations associated with cancers, and deciphering their role in disease progression and response to treatment is one of the major challenges face...
Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease. While there is a scientific basis...
Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
Launched in early 2015, the Precision Medicine Initiative (PMI) takes advantage of the progress made in genomic testing – progress largely driven by rapid advances in DNA sequencing tec...
The starting point for an interaction between a patient and a clinician is almost always a set of clinical facts (aka a phenotype). Phenotype-first medicine is the standard way in which the p...
Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
The use of pluripotent stem cell-derived cell types for disease modeling, drug screening and regenerative medicine is an exciting area of activity in health research. Prior to the availabilit...
This is an introduction to the biological mechanism of RNA interference (RNAi) and experimental application of short, interfering RNA (siRNA). The key steps of the endogenous RNAi pathway wil...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETThe powerful and expanding use of genetically modified mice introduces important aspects of genetics in managing these strains for breedi...
DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETLarge animal models have recently become a staple in biomedical research. The pig’s similarities to humans in terms of genet...
DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
DATE: February 7, 2017TIME: 10:00am PT, 1:00pm ETIn this webinar, Jeffrey G. Reid, PhD, Executive Director and Head of Genome Informatics at Regeneron Pharmaceuticals, will sh...
DATE: January 31, 2017TIME: 9:00AM PT, 12:00PM ET Gautam Dantas - While the most acute effects of increasing antibiotic resistance in pathogens are observed in clinical se...
Flow cytometry is a powerful technique that allows rapid and quantitative measurements of multiple parameter on individual cells simultaneously. Sheath fluid is used to transport these cells...
Cancer biologists, pharmacologists and immunologists have historically communicated little with each other due to different traditions in training and a lack of integrated perspectives on can...
DATE: December 14, 2016TIME: 9:00 AM PT, 12:00 PM ETMicroarrays and nucleotide sequencers have become commonplace tools in current research, yet until now, equivalent technologies for p...
DATE: December 14, 2016
TIME: 7:30am PT, 10:30am ET
A major hurdle in developing relevant disease models for drug discovery is access to the healthy and diseased tissue of interest; induc...
DATE: December 13, 2016TIME: 8:00 AM PT, 11:00 AM ETUnderstanding physiological mechanisms regulating growth and nutrient deposition in rainbow trout is central to establish production...
DATE: December 6, 2016
TIME: 8:00am PT, 11:00am ET
Adverse drug reactions (ADRs) are one of the leading causes of morbidity and mortality in health care. In the US alone, an est...
The generation of induced pluripotent stem cells (iPSCs) from adult easily accessible somatic tissues was introduced ten years ago. This technology has revolutionized our opportunities to stu...
In this talk, I will use examples from my research using big data analytics to define ideals of precision medicine and digital health across a variety of diseases. Specifically, I will i...
Challenges in achieving comparability, reproducibility and accuracy in biological assays has driven a demand for improved confidence in measurements that support development of regenerative m...
Identification of the many complex genetic aberrations associated with cancers, and deciphering their role in disease progression and response to treatment is one of the major challenges face...
Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease. While there is a scientific basis...
Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
Launched in early 2015, the Precision Medicine Initiative (PMI) takes advantage of the progress made in genomic testing – progress largely driven by rapid advances in DNA sequencing tec...
The starting point for an interaction between a patient and a clinician is almost always a set of clinical facts (aka a phenotype). Phenotype-first medicine is the standard way in which the p...
Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
The use of pluripotent stem cell-derived cell types for disease modeling, drug screening and regenerative medicine is an exciting area of activity in health research. Prior to the availabilit...
This is an introduction to the biological mechanism of RNA interference (RNAi) and experimental application of short, interfering RNA (siRNA). The key steps of the endogenous RNAi pathway wil...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETThe powerful and expanding use of genetically modified mice introduces important aspects of genetics in managing these strains for breedi...
DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETLarge animal models have recently become a staple in biomedical research. The pig’s similarities to humans in terms of genet...
DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
DATE: February 7, 2017TIME: 10:00am PT, 1:00pm ETIn this webinar, Jeffrey G. Reid, PhD, Executive Director and Head of Genome Informatics at Regeneron Pharmaceuticals, will sh...
DATE: January 31, 2017TIME: 9:00AM PT, 12:00PM ET Gautam Dantas - While the most acute effects of increasing antibiotic resistance in pathogens are observed in clinical se...
Flow cytometry is a powerful technique that allows rapid and quantitative measurements of multiple parameter on individual cells simultaneously. Sheath fluid is used to transport these cells...
Cancer biologists, pharmacologists and immunologists have historically communicated little with each other due to different traditions in training and a lack of integrated perspectives on can...
DATE: December 14, 2016TIME: 9:00 AM PT, 12:00 PM ETMicroarrays and nucleotide sequencers have become commonplace tools in current research, yet until now, equivalent technologies for p...
DATE: December 14, 2016
TIME: 7:30am PT, 10:30am ET
A major hurdle in developing relevant disease models for drug discovery is access to the healthy and diseased tissue of interest; induc...
DATE: December 13, 2016TIME: 8:00 AM PT, 11:00 AM ETUnderstanding physiological mechanisms regulating growth and nutrient deposition in rainbow trout is central to establish production...
DATE: December 6, 2016
TIME: 8:00am PT, 11:00am ET
Adverse drug reactions (ADRs) are one of the leading causes of morbidity and mortality in health care. In the US alone, an est...
The generation of induced pluripotent stem cells (iPSCs) from adult easily accessible somatic tissues was introduced ten years ago. This technology has revolutionized our opportunities to stu...
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