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    High Throughput

    High throughput cell biology is the use of automation equipment with classical cell biology techniques to address biological questions that are otherwise unattainable using conventional methods. It may incorporate techniques from optics, chemistry, biology or image analysis to permit rapid, highly parallel research into how cells function, interact with each other and how pathogens exploit them in disease. High-throughput biology serves as one facet of what has also been called "omics research" - the interface between large scale biology (genome, proteome, transcriptome), technology and researchers. High throughput cell biology has a definite focus on the cell, and methods accessing the cell such as imaging, gene expression microarrays, or genome wide screening. The basic idea is to take methods normally performed on their own and do a very large number of them without impacting their quality.

    Webinars

    • MAY 20, 2020 | 7:30 AM
      Keynote Presentation: Bridging Multiscale Physiological Systems via Microfluidics- from single cell to tissue-scale to organ-scale
      Keynote Presentation: Bridging Multiscale Physiological Systems...
      Precision medicine is the paradigm to develop treatments for patients based on molecular-targets that are effective in vivo when administered. In addition to identifying the molecular and ce...
      Speaker: Abraham Lee
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Acoustic Ejection Mass Spectrometry for High-Throughput Analysis
      Acoustic Ejection Mass Spectrometry for High-Throughput Analysis
      We describe a mass spectrometry (MS) analytical platform resulting from the novel integration of acoustic droplet ejection (ADE) technology, an open-port interface (OPI), and electrospray io...
      Speaker: Luke Ghislain, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1 1
      MAY 20, 2020 | 12:00 AM
      Next-gen protein assays enabling precision medicine and data-driven biology
      Next-gen protein assays enabling precision medicine and data-driven...
      Proteins are the functional blocks of any biological entity from 50 nm sized viruses to the 100 ft long mammals (blue whale). They perform intra cellular, tissue, organ, system, or organism...
      Speaker: Kursad Araz, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      The Importance of Data Integrity: LIMS, Tools and Best Practices
      The Importance of Data Integrity: LIMS, Tools and Best Practices
      The amount of data that is produced each day is mind boggling. Over 2.5 quintillion bytes of data are created every single day, and this number continues to grow every single day. This year...
      Speaker: Christine Paszko, PhD, MT (ASCP)
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      3
      MAY 20, 2020 | 12:00 AM
      Comprehensive Genomic Association Data for Genetic Variant Interpretation: A Computational Approach
      Comprehensive Genomic Association Data for Genetic Variant Interpretation:...
      Design and interpretation of genome sequencing assays and data in both clinical diagnostics and research labs is complicated by an inability to identify information from the medical literatu...
      Speaker: Mark Kiel, MD, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCRâ„¢
      Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCRâ„¢
      The current gold standard for COVID-19 diagnosis is based on the detection of SARS-CoV-2 nucleic acid using real-time quantitative PCR (RT-qPCR). Recent studies suggest limitations of RT-qPC...
      Speaker: Rémi Dangla
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Single-cell Genomics Tools for better understanding and treatment of Human Disease
      Single-cell Genomics Tools for better understanding and treatment...
      The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
      Speaker: Anindita Basu, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      2
      MAY 20, 2020 | 12:00 AM
      Zero-effort Analytical Method Validation
      Zero-effort Analytical Method Validation
      Analytical Method Validation work is based on a variety of guidelines and requirements hence being time-consuming and stressful. Reducing this work and improving efficiency while ensuring th...
      Speaker: Jürgen Voorgang
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      2
      MAY 20, 2020 | 12:00 AM
      Validation of LIMS is a part of the data integrity
      Validation of LIMS is a part of the data integrity
      LIMS systems are used extensively in laboratories everywhere. As a tool in the lab we need to be able to trust the system to have the necessary data integrity. Just like the analytical metho...
      Speaker: Siri H. Segalstad
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Lab on a Particle: Democratizing Single-Cell Secretion Assays
      Lab on a Particle: Democratizing Single-Cell Secretion Assays
      Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
      Speaker: Joseph de Rutte
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      LAB 4.0 Fully automated LIMS including SAP integration
      LAB 4.0 Fully automated LIMS including SAP integration
      The digital lab is knocking at your door. In the age of digitalization and Industry 4.0, the laboratory is also on its way to the future. Lab 4.0 includes robotic systems, fully automated wo...
      Speaker: Guido von Dahlen
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 20, 2020 | 12:00 AM
      Gene-editing by a "click-of-a-button"
      Gene-editing by a "click-of-a-button"
      If you have ever worked in the field of gene-editing, then you must know the powerful gene-editing technology known as CRISPR. It has the potential to alter science and biotechnology at an i...
      Speaker: Steve Shih, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      1
      MAY 14, 2020 | 10:00 AM
      Massively Parallel Genome Engineering followed by pooled growth selections for rapid target discovery in microbes
      Massively Parallel Genome Engineering followed by pooled growth...
      DATE: May 14, 2020 TIME: 10:00am PT, 1:00pm ET Massively parallel genome engineering enables rapid and simultaneous evaluation of genotype-phenotype relationships at a genomic scale....
      Speaker: Stephen Federowicz, Ph.D.
      Sponsored By: Inscripta
      7
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      MAY 08, 2020 | 10:00 AM
      TCR-seq & BCR-seq Solutions: Applications to Clinical Research Projects
      TCR-seq & BCR-seq Solutions: Applications to Clinical Research...
      DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
      Speaker: Brian O'Connor, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      16 10
      MAY 07, 2020 | 7:00 AM
      A complete workflow for analysis of cfDNA: from plasma to variants
      A complete workflow for analysis of cfDNA: from plasma to variants
      DATE: May 7, 2020 TIME: 7:00am PT As cost of sequencing continues to drop, the throughput and complexity of NGS assays have risen precipitously. At the same time, the types of samples being...
      Speaker: Shilpa Parakh , Nicole Roseman
      Sponsored By: Beckman Coulter Life Sciences, Integrated DNA Technologies (IDT)
      13 10
      MAY 06, 2020 | 12:00 AM
      Deciphering the Necrobiome and Postmortem Microbiomes for Use in Forensics
      Deciphering the Necrobiome and Postmortem Microbiomes for Use...
      The necrobiome is the community of organisms that use or are affected by decomposing organic matter. Decomposing organic matter comes in the form of dead plant matter (biomass) or that of de...
      Speaker: M. Eric Benbow, PhD, AAFS-F
      Presented at: Forensic Sciences Virtual Event Series 2020
      1
      MAY 06, 2020 | 12:00 AM
      The use of massively parallel sequencing in Forensic DNA typing - what will the future hold?
      The use of massively parallel sequencing in Forensic DNA typing...
      The current standard methodology in forensic DNA typing relies on amplification of short tandem repeat (STR) markers by the polymerase chain reaction (PCR) and allele sizes (i.e., length-bas...
      Speaker: Nicole M.M. Novroski, PhD
      Presented at: Forensic Sciences Virtual Event Series 2020
      3
      MAY 06, 2020 | 12:00 AM
      Microhaplotypes: the next generation DNA marker
      Microhaplotypes: the next generation DNA marker
      Learning Objectives: 1. Molecular basis of microhaplotypes 2. Informativeness and power of discrimination of microhaplotypes 3. Mixture deconvolution via microhaplotypes...
      Speaker: Daniele Podini
      Presented at: Forensic Sciences Virtual Event Series 2020
      1
      APR 30, 2020 | 9:00 AM
      Tools and methods for CRISPR-Cas9 screening for functional genomics and drug discovery
      Tools and methods for CRISPR-Cas9 screening for functional genomics...
      DATE: April 30, 2020 TIME: 9:00am PT, 12:00pm ET Loss-of-function studies are an established method for uncovering a gene’s role in a biological pathway or disease state. The advent of...
      Speaker: Louise Baskin, M.S. Molecular Biology and Genetics
      Sponsored By: Thermo Fisher Scientific
      23 1
      APR 29, 2020 | 6:00 AM
      High-Throughput assessment of ChIP-grade capability with Luminex xMAP technology
      High-Throughput assessment of ChIP-grade capability with Luminex...
      Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
      Speaker: Michael-Christopher Keogh, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      APR 29, 2020 | 6:00 AM
      Lessons Learned in the Pursuit of High Throughput Luminex Analysis on a Budget
      Lessons Learned in the Pursuit of High Throughput Luminex Analysis...
      ...
      Speaker: Brian McFarlin, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      APR 29, 2020 | 6:00 AM
      Experimental Design and Analytics for Customized High Throughput Ligand Screening in Developing Affinity Purification Solutions
      Experimental Design and Analytics for Customized High Throughput...
      ...
      Speaker: Sidharth Mohan
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      1
      APR 24, 2020 | 8:00 AM
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
      DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
      Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
      Sponsored By: Bionano
      11
    MAY 20, 2020 | 7:30 AM
    Keynote Presentation: Bridging Multiscale Physiological Systems via Microfluidics- from single cell to tissue-scale to organ-scale
    Keynote Presentation: Bridging Multiscale Physiological Systems...
    Precision medicine is the paradigm to develop treatments for patients based on molecular-targets that are effective in vivo when administered. In addition to identifying the molecular and ce...
    Speaker: Abraham Lee
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    Acoustic Ejection Mass Spectrometry for High-Throughput Analysis
    Acoustic Ejection Mass Spectrometry for High-Throughput Analysis
    We describe a mass spectrometry (MS) analytical platform resulting from the novel integration of acoustic droplet ejection (ADE) technology, an open-port interface (OPI), and electrospray io...
    Speaker: Luke Ghislain, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1 1
    MAY 20, 2020 | 12:00 AM
    Next-gen protein assays enabling precision medicine and data-driven biology
    Next-gen protein assays enabling precision medicine and data-driven...
    Proteins are the functional blocks of any biological entity from 50 nm sized viruses to the 100 ft long mammals (blue whale). They perform intra cellular, tissue, organ, system, or organism...
    Speaker: Kursad Araz, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    The Importance of Data Integrity: LIMS, Tools and Best Practices
    The Importance of Data Integrity: LIMS, Tools and Best Practices
    The amount of data that is produced each day is mind boggling. Over 2.5 quintillion bytes of data are created every single day, and this number continues to grow every single day. This year...
    Speaker: Christine Paszko, PhD, MT (ASCP)
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    3
    MAY 20, 2020 | 12:00 AM
    Comprehensive Genomic Association Data for Genetic Variant Interpretation: A Computational Approach
    Comprehensive Genomic Association Data for Genetic Variant Interpretation:...
    Design and interpretation of genome sequencing assays and data in both clinical diagnostics and research labs is complicated by an inability to identify information from the medical literatu...
    Speaker: Mark Kiel, MD, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
     
     
  • MAY 20, 2020 | 12:00 AM
    Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCRâ„¢
    Highly sensitive detection of SARS-CoV-2 by Crystal Digital PCRâ„¢
    The current gold standard for COVID-19 diagnosis is based on the detection of SARS-CoV-2 nucleic acid using real-time quantitative PCR (RT-qPCR). Recent studies suggest limitations of RT-qPC...
    Speaker: Rémi Dangla
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    Single-cell Genomics Tools for better understanding and treatment of Human Disease
    Single-cell Genomics Tools for better understanding and treatment...
    The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
    Speaker: Anindita Basu, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    2
    MAY 20, 2020 | 12:00 AM
    Zero-effort Analytical Method Validation
    Zero-effort Analytical Method Validation
    Analytical Method Validation work is based on a variety of guidelines and requirements hence being time-consuming and stressful. Reducing this work and improving efficiency while ensuring th...
    Speaker: Jürgen Voorgang
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    2
    MAY 20, 2020 | 12:00 AM
    Validation of LIMS is a part of the data integrity
    Validation of LIMS is a part of the data integrity
    LIMS systems are used extensively in laboratories everywhere. As a tool in the lab we need to be able to trust the system to have the necessary data integrity. Just like the analytical metho...
    Speaker: Siri H. Segalstad
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    Lab on a Particle: Democratizing Single-Cell Secretion Assays
    Lab on a Particle: Democratizing Single-Cell Secretion Assays
    Techniques to analyze and sort single cells based on secreted products have the potential to transform our understanding of cellular biology as well as accelerate the development of next gen...
    Speaker: Joseph de Rutte
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
     
     
  • MAY 20, 2020 | 12:00 AM
    LAB 4.0 Fully automated LIMS including SAP integration
    LAB 4.0 Fully automated LIMS including SAP integration
    The digital lab is knocking at your door. In the age of digitalization and Industry 4.0, the laboratory is also on its way to the future. Lab 4.0 includes robotic systems, fully automated wo...
    Speaker: Guido von Dahlen
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 20, 2020 | 12:00 AM
    Gene-editing by a "click-of-a-button"
    Gene-editing by a "click-of-a-button"
    If you have ever worked in the field of gene-editing, then you must know the powerful gene-editing technology known as CRISPR. It has the potential to alter science and biotechnology at an i...
    Speaker: Steve Shih, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    1
    MAY 14, 2020 | 10:00 AM
    Massively Parallel Genome Engineering followed by pooled growth selections for rapid target discovery in microbes
    Massively Parallel Genome Engineering followed by pooled growth...
    DATE: May 14, 2020 TIME: 10:00am PT, 1:00pm ET Massively parallel genome engineering enables rapid and simultaneous evaluation of genotype-phenotype relationships at a genomic scale....
    Speaker: Stephen Federowicz, Ph.D.
    Sponsored By: Inscripta
    7
    MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
    MAY 08, 2020 | 10:00 AM
    TCR-seq & BCR-seq Solutions: Applications to Clinical Research Projects
    TCR-seq & BCR-seq Solutions: Applications to Clinical Research...
    DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
    Speaker: Brian O'Connor, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    16 10
     
     
  • MAY 07, 2020 | 7:00 AM
    A complete workflow for analysis of cfDNA: from plasma to variants
    A complete workflow for analysis of cfDNA: from plasma to variants
    DATE: May 7, 2020 TIME: 7:00am PT As cost of sequencing continues to drop, the throughput and complexity of NGS assays have risen precipitously. At the same time, the types of samples being...
    Speaker: Shilpa Parakh , Nicole Roseman
    Sponsored By: Beckman Coulter Life Sciences, Integrated DNA Technologies (IDT)
    13 10
    MAY 06, 2020 | 12:00 AM
    Deciphering the Necrobiome and Postmortem Microbiomes for Use in Forensics
    Deciphering the Necrobiome and Postmortem Microbiomes for Use...
    The necrobiome is the community of organisms that use or are affected by decomposing organic matter. Decomposing organic matter comes in the form of dead plant matter (biomass) or that of de...
    Speaker: M. Eric Benbow, PhD, AAFS-F
    Presented at: Forensic Sciences Virtual Event Series 2020
    1
    MAY 06, 2020 | 12:00 AM
    The use of massively parallel sequencing in Forensic DNA typing - what will the future hold?
    The use of massively parallel sequencing in Forensic DNA typing...
    The current standard methodology in forensic DNA typing relies on amplification of short tandem repeat (STR) markers by the polymerase chain reaction (PCR) and allele sizes (i.e., length-bas...
    Speaker: Nicole M.M. Novroski, PhD
    Presented at: Forensic Sciences Virtual Event Series 2020
    3
    MAY 06, 2020 | 12:00 AM
    Microhaplotypes: the next generation DNA marker
    Microhaplotypes: the next generation DNA marker
    Learning Objectives: 1. Molecular basis of microhaplotypes 2. Informativeness and power of discrimination of microhaplotypes 3. Mixture deconvolution via microhaplotypes...
    Speaker: Daniele Podini
    Presented at: Forensic Sciences Virtual Event Series 2020
    1
    APR 30, 2020 | 9:00 AM
    Tools and methods for CRISPR-Cas9 screening for functional genomics and drug discovery
    Tools and methods for CRISPR-Cas9 screening for functional genomics...
    DATE: April 30, 2020 TIME: 9:00am PT, 12:00pm ET Loss-of-function studies are an established method for uncovering a gene’s role in a biological pathway or disease state. The advent of...
    Speaker: Louise Baskin, M.S. Molecular Biology and Genetics
    Sponsored By: Thermo Fisher Scientific
    23 1
     
     
  • APR 29, 2020 | 6:00 AM
    High-Throughput assessment of ChIP-grade capability with Luminex xMAP technology
    High-Throughput assessment of ChIP-grade capability with Luminex...
    Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
    Speaker: Michael-Christopher Keogh, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    APR 29, 2020 | 6:00 AM
    Lessons Learned in the Pursuit of High Throughput Luminex Analysis on a Budget
    Lessons Learned in the Pursuit of High Throughput Luminex Analysis...
    ...
    Speaker: Brian McFarlin, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    APR 29, 2020 | 6:00 AM
    Experimental Design and Analytics for Customized High Throughput Ligand Screening in Developing Affinity Purification Solutions
    Experimental Design and Analytics for Customized High Throughput...
    ...
    Speaker: Sidharth Mohan
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    1
    APR 24, 2020 | 8:00 AM
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
    DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
    Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
    Sponsored By: Bionano
    11
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