High throughput cell biology is the use of automation equipment with classical cell biology techniques to address biological questions that are otherwise unattainable using conventional methods. It may incorporate techniques from optics, chemistry, biology or image analysis to permit rapid, highly parallel research into how cells function, interact with each other and how pathogens exploit them in disease. High-throughput biology serves as one facet of what has also been called "omics research" - the interface between large scale biology (genome, proteome, transcriptome), technology and researchers. High throughput cell biology has a definite focus on the cell, and methods accessing the cell such as imaging, gene expression microarrays, or genome wide screening. The basic idea is to take methods normally performed on their own and do a very large number of them without impacting their quality.
The use of three‐dimensional (3D) culture models is rapidly expanding due to their recognition as representing more structurally and physiologically relevant models of in vivo biology. 3D ce...
Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
DATE: July 8, 2020 TIME: 8:00am PDT In this webinar, discover how targeted protein degradation is being used to drive drug discovery. Hosted by Gary Allenby, Chief Executive Officer of Aurel...
The need for high-throughput laboratory testing to identify SARS-CoV-2 infected individuals has reached nearly unprecedented levels. This demand has also led to supply chain issues that have...
Molecular breeding can significantly reduce the cost and time required to deliver improved plant and animal species for agricultural use. Advancements in genomic technologies are acceleratin...
MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post transcriptional level. They are known to play a critical role in multiple biologi...
DATE: July 1, 2020 TIME: 8:00 am PDT, 11:00 am EDT In late 2019, researchers identified the SARS-CoV-2 pathogen as the virus responsible for COVID-19. The virus spread rapidly throughout the...
Next generation genomics technology is playing a significant role in improving the outcomes of genomic tools used in livestock farming, cultivation of crops, selection of quality seeds with...
DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
DATE: June 30, 2020 TIME: 8:00am PT, 11:00am Understanding the tumor microenvironment (TME) is essential for the development of effective treatments for cancer patients. Traditional multi...
DATE: June 25, 2020 TIME: 7:00am PT Genotyping assays are essential in a variety of plant and animal applications including Marker Assisted Selection (MAS) and Quantitative Trait Locus (QTL)...
The 2020 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to rage. While PCR-based assays are used for viral diagnosis, high through-put, rapid s...
DATE: June 16, 2020 TIME: 8:00am PT Multi-wavelength analysis of hydrodynamic data collected on the latest analytical ultracentrifugation instruments provides additional resolution and insig...
Dr. Koenitzer will present an overview of her current research in immune suppression. After a brief introduction to the MILLIPLEX® multiplex immunoassay portfolio, Dr. Koenitzer will dis...
Recent developments in reporters for calcium, voltage, and neurotransmitters, together with interest in understanding neuronal circuit function, have driven the development of methods for fa...
Recent advances in high-throughput single-cell transcriptomics and epigenomics methods allow to measure the expression of thousands of genes and identify the gene transcriptional regulation...
A recently proposed model for the incorporation of xenobiotics of clinical and forensic interest into the human skeleton suggests nerve agent metabolites may incorporate into bone at relativ...
Many questions at the forefront of biology depend on the interactions of millions of single cells. My lab develops technologies for studying large numbers of single cells. In this talk, I wi...
Precision medicine is the paradigm to develop treatments for patients based on molecular-targets that are effective in vivo when administered. In addition to identifying the molecular and ce...
The current gold standard for COVID-19 diagnosis is based on the detection of SARS-CoV-2 nucleic acid using real-time quantitative PCR (RT-qPCR). Recent studies suggest limitations of RT-qPC...
The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
Analytical Method Validation work is based on a variety of guidelines and requirements hence being time-consuming and stressful. Reducing this work and improving efficiency while ensuring th...
LIMS systems are used extensively in laboratories everywhere. As a tool in the lab we need to be able to trust the system to have the necessary data integrity. Just like the analytical metho...
The use of three‐dimensional (3D) culture models is rapidly expanding due to their recognition as representing more structurally and physiologically relevant models of in vivo biology. 3D ce...
Metastasis is the main cause of death in cancer patients and one of the most complex biological processes in human diseases (Hanahan et al., 2011). The development of therapies designed to f...
DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
DATE: July 8, 2020 TIME: 8:00am PDT In this webinar, discover how targeted protein degradation is being used to drive drug discovery. Hosted by Gary Allenby, Chief Executive Officer of Aurel...
The need for high-throughput laboratory testing to identify SARS-CoV-2 infected individuals has reached nearly unprecedented levels. This demand has also led to supply chain issues that have...
Molecular breeding can significantly reduce the cost and time required to deliver improved plant and animal species for agricultural use. Advancements in genomic technologies are acceleratin...
MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post transcriptional level. They are known to play a critical role in multiple biologi...
DATE: July 1, 2020 TIME: 8:00 am PDT, 11:00 am EDT In late 2019, researchers identified the SARS-CoV-2 pathogen as the virus responsible for COVID-19. The virus spread rapidly throughout the...
Next generation genomics technology is playing a significant role in improving the outcomes of genomic tools used in livestock farming, cultivation of crops, selection of quality seeds with...
DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
DATE: June 30, 2020 TIME: 8:00am PT, 11:00am Understanding the tumor microenvironment (TME) is essential for the development of effective treatments for cancer patients. Traditional multi...
DATE: June 25, 2020 TIME: 7:00am PT Genotyping assays are essential in a variety of plant and animal applications including Marker Assisted Selection (MAS) and Quantitative Trait Locus (QTL)...
The 2020 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to rage. While PCR-based assays are used for viral diagnosis, high through-put, rapid s...
DATE: June 16, 2020 TIME: 8:00am PT Multi-wavelength analysis of hydrodynamic data collected on the latest analytical ultracentrifugation instruments provides additional resolution and insig...
Dr. Koenitzer will present an overview of her current research in immune suppression. After a brief introduction to the MILLIPLEX® multiplex immunoassay portfolio, Dr. Koenitzer will dis...
Recent developments in reporters for calcium, voltage, and neurotransmitters, together with interest in understanding neuronal circuit function, have driven the development of methods for fa...
Recent advances in high-throughput single-cell transcriptomics and epigenomics methods allow to measure the expression of thousands of genes and identify the gene transcriptional regulation...
A recently proposed model for the incorporation of xenobiotics of clinical and forensic interest into the human skeleton suggests nerve agent metabolites may incorporate into bone at relativ...
Many questions at the forefront of biology depend on the interactions of millions of single cells. My lab develops technologies for studying large numbers of single cells. In this talk, I wi...
Precision medicine is the paradigm to develop treatments for patients based on molecular-targets that are effective in vivo when administered. In addition to identifying the molecular and ce...
The current gold standard for COVID-19 diagnosis is based on the detection of SARS-CoV-2 nucleic acid using real-time quantitative PCR (RT-qPCR). Recent studies suggest limitations of RT-qPC...
The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
Analytical Method Validation work is based on a variety of guidelines and requirements hence being time-consuming and stressful. Reducing this work and improving efficiency while ensuring th...
LIMS systems are used extensively in laboratories everywhere. As a tool in the lab we need to be able to trust the system to have the necessary data integrity. Just like the analytical metho...
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