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    High Throughput

    High throughput cell biology is the use of automation equipment with classical cell biology techniques to address biological questions that are otherwise unattainable using conventional methods. It may incorporate techniques from optics, chemistry, biology or image analysis to permit rapid, highly parallel research into how cells function, interact with each other and how pathogens exploit them in disease. High-throughput biology serves as one facet of what has also been called "omics research" - the interface between large scale biology (genome, proteome, transcriptome), technology and researchers. High throughput cell biology has a definite focus on the cell, and methods accessing the cell such as imaging, gene expression microarrays, or genome wide screening. The basic idea is to take methods normally performed on their own and do a very large number of them without impacting their quality.

    Webinars

    • SEP 24, 2014 | 5:00 AM
      Exploring macrocycles for drug discovery: Novel lead series for challenging protein-protein interactions
      Exploring macrocycles for drug discovery: Novel lead series for...
      Macrocycles offer a new structural class that has the potential to address challenging protein-protein interaction targets and still present attractive drug-like properties including cell mem...
      Speaker: Nick K. Terrett, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      16
      AUG 21, 2014 | 11:30 AM
      Automation of High Throughput Agarose Gel Electrophoresis with the NIMBUS Select Featuring Ranger Technology
      Automation of High Throughput Agarose Gel Electrophoresis with...
      Coastal Genomics and the Hamilton Company have teamed up to combine the NIMBUS 96 channel platform with Ranger Technology to automate high throughput agarose gel electrophoresis. The new NIM...
      Speaker: Matthew Nesbitt, MSc
      Presented at: Genetics and Genomics Virtual Event Series 2014
      0
      AUG 21, 2014 | 10:45 AM
      The Role of Genetic Counselors in the Implementation of Personalized Genomic Medicine
      The Role of Genetic Counselors in the Implementation of Personalized...
      For personalized genomic medicine (PGM) to be readily adopted into clinical practice, there is a need for a multidisciplinary team, and a need to educate health care professionals and the...
      Speaker: Colleen Campbell, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      128
      AUG 21, 2014 | 8:45 AM
      Genome and exome sequencing in a clinical laboratory
      Genome and exome sequencing in a clinical laboratory
      With advances in next-generation sequencing, whole-exome and genome sequencing (WGES) is now accessible as a tool in many applications. In the clinical setting, WGES is proving to be very val...
      Speaker: Matthew Lebo, PhD, FACMG
      Presented at: Genetics and Genomics Virtual Event Series 2014
      30
      AUG 21, 2014 | 6:00 AM
      Landscape and variation of RNA secondary structures in the human transcriptome
      Landscape and variation of RNA secondary structures in the human...
      ...
      Speaker: Yue Wan, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
      AUG 20, 2014 | 11:30 AM
      More Comprehensive Views of Human Genetic Variation
      More Comprehensive Views of Human Genetic Variation
      High-throughput short-read DNA sequencing has revolutionized our ability to measure genetic variation in the form of single-nucleotide polymorphisms (SNPs) in human genomes. However, ~75% of...
      Speaker: Jonas Korlach, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      8
      AUG 20, 2014 | 8:45 AM
      Novel gene chip technologies and NGS sequencing for personalized medicine & diagnostic
      Novel gene chip technologies and NGS sequencing for personalized...
      The flexibility of the BioMark Real-Time PCR System, allow us to preform genetic research using different types of nano-fluidic (48.48 or 96.96) chips setup, in the thermal cycle of these chi...
      Speaker: Dani Bercovich, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
      AUG 20, 2014 | 7:30 AM
      Panel Discussion: Increasing productivity and reproducibility by automating DNA library preparation for Ion Torrent Sequencing
      Panel Discussion: Increasing productivity and reproducibility...
      Next Generation Sequencing has revolutionized genomic variant discovery. The major bottle-neck for sequencing projects is the individual, biological sample, library preparation. This platfo...
      Speaker: Joanna Hamilton, PhD, Lynne Apone, PhD, Zach Smith, MS
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
      AUG 20, 2014 | 7:15 AM
      Establishing cell-free biology for the production of therapeutics, materials, and chemicals
      Establishing cell-free biology for the production of therapeutics,...
      Imagine a world in which we could adapt biology to manufacture any therapeutic, material, or chemical from renewable resources, both quickly and on demand. Industrial biotechnology is one of...
      Speaker: Michael C Jewett, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      11
      JUL 10, 2014 | 9:00 AM
      More Predictive Results in Cell-Based Assays
      More Predictive Results in Cell-Based Assays
       In this webinar, our expert panel of speakers will introduce the new EnSight™ Multimode Plate Reader from PerkinElmer and demonstrate how the unique combination of well-imagin...
      Speaker: Dr. Philip Gribbon, Dr. Volker Eckelt, Dr. Norbert Garbow
      Revvity
      18
      JUL 10, 2014 | 1:00 AM
      More Predictive Results in Cell-Based Assays
      More Predictive Results in Cell-Based Assays
      In this webinar, our expert panel of speakers will introduce the new EnSight™ Multimode Plate Reader from PerkinElmer and demonstrate how the unique combination of well-imaging with lab...
      Speaker: Dr. Philip Gribbon, Dr. Volker Eckelt, Dr. Norbert Garbow
      Sponsored By: Revvity
      17
      MAY 29, 2014 | 7:30 AM
      Identification of predictive biomarkers from high throughput drug combination screening data
      Identification of predictive biomarkers from high throughput drug...
      One of the major challenges to oncology based drug discovery and development has been the limited or incremental impact that many targeted agents have exhibited in the clinic. Understanding a...
      Speaker: Emma Bowden, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      20
      APR 17, 2014 | 11:00 AM
      A Novel Method of Active Paraffin Removal
      A Novel Method of Active Paraffin Removal
        Formalin Fixation and Paraffin Embedding (FFPE) of tissue samples is a routine practice by pathologists; the technique enables high quality preservation of structural information. However, ...
      Speaker: Hamid Khoja, PhD,
      Sponsored By: Covaris, Covaris
      78
      MAR 20, 2014 | 1:00 PM
      The role of high throughput sequencing in the research and diagnosis of neurodegenerative disorders
      The role of high throughput sequencing in the research and diagnosis...
      Using high throughput next-generation sequencing to simultaneously search large number of genes for pathogenic mutations has numerous advantages. It decreases the pressure to narrow the dif...
      Speaker: Peter L Nagy, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      0
      MAR 19, 2014 | 9:00 AM
      Remyelinating the adult central nervous system: Repairing injury in  MS
      Remyelinating the adult central nervous system: Repairing injury...
      Multiple Sclerosis is a debilitating neurodegnerative disease of the central nervous system in which the immune system targets and destroys myelin sheaths surrounding axons. Progressive a...
      Speaker: Ari Green, MD
      Presented at: Neuroscience Virtual Event Series 2014
      0
      FEB 28, 2014 | 8:00 AM
      C.E. CREDITS
      Panel - Universal Newborn Screening Research for Severe Combined Immunodeficiency
      Panel - Universal Newborn Screening Research for Severe Combined...
      ...
      Speaker: Jelili Ojodu, MPH, Mei Baker, MD, Anne Comeau, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Rare Disease Day
      30
      OCT 17, 2013 | 8:00 AM
      C.E. CREDITS
      Next-generation Cancer Care in the Age of Genomics, Precision Medicine, High Throughput Biology
      Next-generation Cancer Care in the Age of Genomics, Precision...
      Developments in DNA sequencing technology have provided a unique opportunity for diagnosis and discovery of genetic alterations for rare diseases. Partnering with 20 academic centers in the U...
      Speaker: C Jimmy Lin, MD, PhD, MHS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      52
      OCT 16, 2013 | 2:00 PM
      C.E. CREDITS
      Novel therapies for ALK mutated cancers
      Novel therapies for ALK mutated cancers
      Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
      Speaker: Roberto Chiarle, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      32
      OCT 16, 2013 | 12:00 PM
      Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based Proteomics and Digital Pathology
      Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based...
      The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision making. Th...
      Speaker: William M. Gallagher, PhD.
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      98
      AUG 22, 2013 | 3:00 PM
      Next-generation Cancer Care in the Age of Genomics, Precision Medicine, High Throughput Biology
      Next-generation Cancer Care in the Age of Genomics, Precision...
      Developments in DNA sequencing technology have provided a unique opportunity for diagnosis and discovery of genetic alterations for rare diseases. Partnering with 20 academic centers in the U...
      Speaker: C Jimmy Lin, MD, PhD, MHS
      Presented at: Genetics and Genomics Virtual Event Series 2013
      114
      AUG 22, 2013 | 3:00 PM
      C.E. CREDITS
      Evaluation challenges and regulatory considerations for next-generation sequencing and other high throughput genomic technology based clinical applications
      Evaluation challenges and regulatory considerations for next-generation...
      The use of ultrahigh throughput diagnostic tests that determine genetic sequence variation to guide patient care is rapidly expanding, fueled by the enormous growth in sequencing platform dev...
      Speaker: Živana Težak, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      282
      AUG 22, 2013 | 1:00 PM
      Dominant regulation of gene expression by microRNAs
      Dominant regulation of gene expression by microRNAs
      MicroRNAs are short non-coding cellular regulators of gene expression. Each microRNA controls the expression of a large set of genes, and microRNAs collectively, may regulate more than half o...
      Speaker: Noam Shomron, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      121
      AUG 21, 2013 | 4:00 PM
      C.E. CREDITS
      The hidden layer of RNA regulation in human development
      The hidden layer of RNA regulation in human development
      High throughput transcriptomic analyses have shown that most of the human genome is dynamically transcribed to produce an extraordinary range of overlapping and interlacing intronic, intergen...
      Speaker: John Mattick, PhD,AO, FAA, FRCPA
      Presented at: Genetics and Genomics Virtual Event Series 2013
      132
      AUG 21, 2013 | 11:00 AM
      Panel Discussion: Meeting the Demand of Increased NGS Capacity with Automated TruSeq Stranded mRNA Library Preparation
      Panel Discussion: Meeting the Demand of Increased NGS Capacity...
      RNASeq has become the primary method for studying changes in gene expression in modern genomics research. By directly sequencing the various types of RNA molecules, including mRNA, ncRNA, an...
      Speaker: Alisa Jackson, Zach Smith, Mary Blair, Dave Delano
      Presented at: Genetics and Genomics Virtual Event Series 2013
      41
    SEP 24, 2014 | 5:00 AM
    Exploring macrocycles for drug discovery: Novel lead series for challenging protein-protein interactions
    Exploring macrocycles for drug discovery: Novel lead series for...
    Macrocycles offer a new structural class that has the potential to address challenging protein-protein interaction targets and still present attractive drug-like properties including cell mem...
    Speaker: Nick K. Terrett, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    16
    AUG 21, 2014 | 11:30 AM
    Automation of High Throughput Agarose Gel Electrophoresis with the NIMBUS Select Featuring Ranger Technology
    Automation of High Throughput Agarose Gel Electrophoresis with...
    Coastal Genomics and the Hamilton Company have teamed up to combine the NIMBUS 96 channel platform with Ranger Technology to automate high throughput agarose gel electrophoresis. The new NIM...
    Speaker: Matthew Nesbitt, MSc
    Presented at: Genetics and Genomics Virtual Event Series 2014
    0
    AUG 21, 2014 | 10:45 AM
    The Role of Genetic Counselors in the Implementation of Personalized Genomic Medicine
    The Role of Genetic Counselors in the Implementation of Personalized...
    For personalized genomic medicine (PGM) to be readily adopted into clinical practice, there is a need for a multidisciplinary team, and a need to educate health care professionals and the...
    Speaker: Colleen Campbell, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    128
    AUG 21, 2014 | 8:45 AM
    Genome and exome sequencing in a clinical laboratory
    Genome and exome sequencing in a clinical laboratory
    With advances in next-generation sequencing, whole-exome and genome sequencing (WGES) is now accessible as a tool in many applications. In the clinical setting, WGES is proving to be very val...
    Speaker: Matthew Lebo, PhD, FACMG
    Presented at: Genetics and Genomics Virtual Event Series 2014
    30
    AUG 21, 2014 | 6:00 AM
    Landscape and variation of RNA secondary structures in the human transcriptome
    Landscape and variation of RNA secondary structures in the human...
    ...
    Speaker: Yue Wan, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
     
     
  • AUG 20, 2014 | 11:30 AM
    More Comprehensive Views of Human Genetic Variation
    More Comprehensive Views of Human Genetic Variation
    High-throughput short-read DNA sequencing has revolutionized our ability to measure genetic variation in the form of single-nucleotide polymorphisms (SNPs) in human genomes. However, ~75% of...
    Speaker: Jonas Korlach, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    8
    AUG 20, 2014 | 8:45 AM
    Novel gene chip technologies and NGS sequencing for personalized medicine & diagnostic
    Novel gene chip technologies and NGS sequencing for personalized...
    The flexibility of the BioMark Real-Time PCR System, allow us to preform genetic research using different types of nano-fluidic (48.48 or 96.96) chips setup, in the thermal cycle of these chi...
    Speaker: Dani Bercovich, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
    AUG 20, 2014 | 7:30 AM
    Panel Discussion: Increasing productivity and reproducibility by automating DNA library preparation for Ion Torrent Sequencing
    Panel Discussion: Increasing productivity and reproducibility...
    Next Generation Sequencing has revolutionized genomic variant discovery. The major bottle-neck for sequencing projects is the individual, biological sample, library preparation. This platfo...
    Speaker: Joanna Hamilton, PhD, Lynne Apone, PhD, Zach Smith, MS
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
    AUG 20, 2014 | 7:15 AM
    Establishing cell-free biology for the production of therapeutics, materials, and chemicals
    Establishing cell-free biology for the production of therapeutics,...
    Imagine a world in which we could adapt biology to manufacture any therapeutic, material, or chemical from renewable resources, both quickly and on demand. Industrial biotechnology is one of...
    Speaker: Michael C Jewett, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    11
    JUL 10, 2014 | 9:00 AM
    More Predictive Results in Cell-Based Assays
    More Predictive Results in Cell-Based Assays
     In this webinar, our expert panel of speakers will introduce the new EnSight™ Multimode Plate Reader from PerkinElmer and demonstrate how the unique combination of well-imagin...
    Speaker: Dr. Philip Gribbon, Dr. Volker Eckelt, Dr. Norbert Garbow
    Revvity
    18
     
     
  • JUL 10, 2014 | 1:00 AM
    More Predictive Results in Cell-Based Assays
    More Predictive Results in Cell-Based Assays
    In this webinar, our expert panel of speakers will introduce the new EnSight™ Multimode Plate Reader from PerkinElmer and demonstrate how the unique combination of well-imaging with lab...
    Speaker: Dr. Philip Gribbon, Dr. Volker Eckelt, Dr. Norbert Garbow
    Sponsored By: Revvity
    17
    MAY 29, 2014 | 7:30 AM
    Identification of predictive biomarkers from high throughput drug combination screening data
    Identification of predictive biomarkers from high throughput drug...
    One of the major challenges to oncology based drug discovery and development has been the limited or incremental impact that many targeted agents have exhibited in the clinic. Understanding a...
    Speaker: Emma Bowden, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    20
    APR 17, 2014 | 11:00 AM
    A Novel Method of Active Paraffin Removal
    A Novel Method of Active Paraffin Removal
      Formalin Fixation and Paraffin Embedding (FFPE) of tissue samples is a routine practice by pathologists; the technique enables high quality preservation of structural information. However, ...
    Speaker: Hamid Khoja, PhD,
    Sponsored By: Covaris, Covaris
    78
    MAR 20, 2014 | 1:00 PM
    The role of high throughput sequencing in the research and diagnosis of neurodegenerative disorders
    The role of high throughput sequencing in the research and diagnosis...
    Using high throughput next-generation sequencing to simultaneously search large number of genes for pathogenic mutations has numerous advantages. It decreases the pressure to narrow the dif...
    Speaker: Peter L Nagy, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    0
    MAR 19, 2014 | 9:00 AM
    Remyelinating the adult central nervous system: Repairing injury in  MS
    Remyelinating the adult central nervous system: Repairing injury...
    Multiple Sclerosis is a debilitating neurodegnerative disease of the central nervous system in which the immune system targets and destroys myelin sheaths surrounding axons. Progressive a...
    Speaker: Ari Green, MD
    Presented at: Neuroscience Virtual Event Series 2014
    0
     
     
  • FEB 28, 2014 | 8:00 AM
    C.E. CREDITS
    Panel - Universal Newborn Screening Research for Severe Combined Immunodeficiency
    Panel - Universal Newborn Screening Research for Severe Combined...
    ...
    Speaker: Jelili Ojodu, MPH, Mei Baker, MD, Anne Comeau, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Rare Disease Day
    30
    OCT 17, 2013 | 8:00 AM
    C.E. CREDITS
    Next-generation Cancer Care in the Age of Genomics, Precision Medicine, High Throughput Biology
    Next-generation Cancer Care in the Age of Genomics, Precision...
    Developments in DNA sequencing technology have provided a unique opportunity for diagnosis and discovery of genetic alterations for rare diseases. Partnering with 20 academic centers in the U...
    Speaker: C Jimmy Lin, MD, PhD, MHS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    52
    OCT 16, 2013 | 2:00 PM
    C.E. CREDITS
    Novel therapies for ALK mutated cancers
    Novel therapies for ALK mutated cancers
    Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
    Speaker: Roberto Chiarle, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    32
    OCT 16, 2013 | 12:00 PM
    Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based Proteomics and Digital Pathology
    Fast-Tracking Molecular Diagnostics in Oncology via Antibody-Based...
    The effective implementation of personalised cancer therapeutic regimens depends on the successful identification and translation of informative biomarkers to aid clinical decision making. Th...
    Speaker: William M. Gallagher, PhD.
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    98
    AUG 22, 2013 | 3:00 PM
    Next-generation Cancer Care in the Age of Genomics, Precision Medicine, High Throughput Biology
    Next-generation Cancer Care in the Age of Genomics, Precision...
    Developments in DNA sequencing technology have provided a unique opportunity for diagnosis and discovery of genetic alterations for rare diseases. Partnering with 20 academic centers in the U...
    Speaker: C Jimmy Lin, MD, PhD, MHS
    Presented at: Genetics and Genomics Virtual Event Series 2013
    114
     
     
  • AUG 22, 2013 | 3:00 PM
    C.E. CREDITS
    Evaluation challenges and regulatory considerations for next-generation sequencing and other high throughput genomic technology based clinical applications
    Evaluation challenges and regulatory considerations for next-generation...
    The use of ultrahigh throughput diagnostic tests that determine genetic sequence variation to guide patient care is rapidly expanding, fueled by the enormous growth in sequencing platform dev...
    Speaker: Živana Težak, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    282
    AUG 22, 2013 | 1:00 PM
    Dominant regulation of gene expression by microRNAs
    Dominant regulation of gene expression by microRNAs
    MicroRNAs are short non-coding cellular regulators of gene expression. Each microRNA controls the expression of a large set of genes, and microRNAs collectively, may regulate more than half o...
    Speaker: Noam Shomron, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    121
    AUG 21, 2013 | 4:00 PM
    C.E. CREDITS
    The hidden layer of RNA regulation in human development
    The hidden layer of RNA regulation in human development
    High throughput transcriptomic analyses have shown that most of the human genome is dynamically transcribed to produce an extraordinary range of overlapping and interlacing intronic, intergen...
    Speaker: John Mattick, PhD,AO, FAA, FRCPA
    Presented at: Genetics and Genomics Virtual Event Series 2013
    132
    AUG 21, 2013 | 11:00 AM
    Panel Discussion: Meeting the Demand of Increased NGS Capacity with Automated TruSeq Stranded mRNA Library Preparation
    Panel Discussion: Meeting the Demand of Increased NGS Capacity...
    RNASeq has become the primary method for studying changes in gene expression in modern genomics research. By directly sequencing the various types of RNA molecules, including mRNA, ncRNA, an...
    Speaker: Alisa Jackson, Zach Smith, Mary Blair, Dave Delano
    Presented at: Genetics and Genomics Virtual Event Series 2013
    41
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