Imaging: the technique and process of creating visual representations of the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities. Although imaging of removed organs and tissues can be performed for medical reasons, such procedures are usually considered part of pathology instead of medical imaging.
Genomics has had rapid implementation over the past decade, with recent growth in application in oncology, mental health, maternal fetal medicine, solid organ transplantation, and more. Much...
The COVID-19 pandemic has taken a dramatic toll worldwide. Its impact possibly has been the most palpable amongst uniquely vulnerable groups of patients, such as patients with a cancer diagn...
Objective : Evaluation of EDTA-gel blood collection tubes from remote locations for NIPS (Non-invasive prenatal testing). Design: Paired comparisons Population: 61 pregnant women from Britis...
Esophageal adenocarcinoma [EAC] is the fastest growing in incidence cancer in the US over the last 25 years, while also having a 5 year survival of less than 20%. Barrett’s Esophagus [...
Follow us on a journey of single cell data exploration. See how you can Process, Analyze, Compare, and Contextualize, your results to identify novel biological relationships and drive new hy...
MicroRNAs (miRNAs) are small RNAs with an average size of 22 nucleotides that regulate gene expression through various mechanisms. During the last decade, researchers have identified over 26...
Regardless of method, single cell RNA-seq only captures a small fraction of the transcriptome of each cell. Often, this is due to inherent limitations of the methodology as reads ‘drop...
Targeted sequencing has many applications in cancer biomarker research, carrier screening and inherited disorders, drug development, mitochondrial DNA variant detection, human ID and paterni...
Loop-mediated isothermal amplification (LAMP) uses a stand-displacing DNA polymerase and four to six primers to rapidly amplify DNA at a single temperature. By eliminating temperature cyclin...
Revolutionary sequencing technologies are enabling whole transcriptome profiling of tens to hundreds of thousands of single cells in parallel, in a single experiment. This has led to an expl...
Learning Objectives: 1. Discuss the potential for newborn screening by whole genome sequencing. 2. Review the current evidence for the sensitivity and specificity of newborn screening by who...
While early genetic diagnosis can guide critical care management, the turnaround time for whole genome based diagnostic testing is months. Recent programs in neonatal populations have reduce...
Target enrichment workflows for Next Generation Sequencing are well-established methods that enable labs to achieve relatively low sequencing costs by specifically sequencing regions of inte...
Pathogen detection and surveillance have become a high priority in both healthcare and environmental settings for the safety of patients and the general public. The COVID-19 pandemic highlig...
Long read Structural Variation calling remains a challenging but highly accurate way to identify complex genomic alterations. To address this challenge, we developed Sniffles2, a successor t...
The CYP2D6 enzyme metabolizes approximately 25% of commonly used pharmaceuticals and is of intense pharmacogenetic interest. Polymorphisms in CYP2D6 can alter an individual’s response...
The human genome encodes 25,000 genes. But the biological complexity inherent in polygenic traits is a clear sign that the whole is greater than the sum of its parts. Genes, gene products, a...
Next-generation sequencing (NGS) has become a foundational tool for both biological research and in-vitro diagnostics, particularly in oncology, immunology, and detection of genetic disorder...
Recurrently emerging SARS-CoV-2 variants of concern (VOC) present increasingly sophisticated immune escape strategies that fuel global infection rates, as exemplified by the raging B.1.1.529...
Understanding the order in which mutations accumulate during cancer progression could help us identify effective therapeutic targets. Yet, our insights are limited by the fact that we can on...
The combination of the wealth of genomic and phenotypic datasets to the measurement of the circulating proteome enables a snapshot of real-time biology and important results for determining...
Infectious disease monitoring on Oxford Nanopore Technologies (ONT) platforms offers rapid turnaround times and low cost. Tracking low frequency intra-host variants provides important insigh...
Date: April 14, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CET) Across oncology applications, from research to molecular testing and pharmaceutical development, the ability to identify...
Genomics has had rapid implementation over the past decade, with recent growth in application in oncology, mental health, maternal fetal medicine, solid organ transplantation, and more. Much...
The COVID-19 pandemic has taken a dramatic toll worldwide. Its impact possibly has been the most palpable amongst uniquely vulnerable groups of patients, such as patients with a cancer diagn...
Objective : Evaluation of EDTA-gel blood collection tubes from remote locations for NIPS (Non-invasive prenatal testing). Design: Paired comparisons Population: 61 pregnant women from Britis...
Esophageal adenocarcinoma [EAC] is the fastest growing in incidence cancer in the US over the last 25 years, while also having a 5 year survival of less than 20%. Barrett’s Esophagus [...
Follow us on a journey of single cell data exploration. See how you can Process, Analyze, Compare, and Contextualize, your results to identify novel biological relationships and drive new hy...
MicroRNAs (miRNAs) are small RNAs with an average size of 22 nucleotides that regulate gene expression through various mechanisms. During the last decade, researchers have identified over 26...
Regardless of method, single cell RNA-seq only captures a small fraction of the transcriptome of each cell. Often, this is due to inherent limitations of the methodology as reads ‘drop...
Targeted sequencing has many applications in cancer biomarker research, carrier screening and inherited disorders, drug development, mitochondrial DNA variant detection, human ID and paterni...
Loop-mediated isothermal amplification (LAMP) uses a stand-displacing DNA polymerase and four to six primers to rapidly amplify DNA at a single temperature. By eliminating temperature cyclin...
Revolutionary sequencing technologies are enabling whole transcriptome profiling of tens to hundreds of thousands of single cells in parallel, in a single experiment. This has led to an expl...
Learning Objectives: 1. Discuss the potential for newborn screening by whole genome sequencing. 2. Review the current evidence for the sensitivity and specificity of newborn screening by who...
While early genetic diagnosis can guide critical care management, the turnaround time for whole genome based diagnostic testing is months. Recent programs in neonatal populations have reduce...
Target enrichment workflows for Next Generation Sequencing are well-established methods that enable labs to achieve relatively low sequencing costs by specifically sequencing regions of inte...
Pathogen detection and surveillance have become a high priority in both healthcare and environmental settings for the safety of patients and the general public. The COVID-19 pandemic highlig...
Long read Structural Variation calling remains a challenging but highly accurate way to identify complex genomic alterations. To address this challenge, we developed Sniffles2, a successor t...
The CYP2D6 enzyme metabolizes approximately 25% of commonly used pharmaceuticals and is of intense pharmacogenetic interest. Polymorphisms in CYP2D6 can alter an individual’s response...
The human genome encodes 25,000 genes. But the biological complexity inherent in polygenic traits is a clear sign that the whole is greater than the sum of its parts. Genes, gene products, a...
Next-generation sequencing (NGS) has become a foundational tool for both biological research and in-vitro diagnostics, particularly in oncology, immunology, and detection of genetic disorder...
Recurrently emerging SARS-CoV-2 variants of concern (VOC) present increasingly sophisticated immune escape strategies that fuel global infection rates, as exemplified by the raging B.1.1.529...
Understanding the order in which mutations accumulate during cancer progression could help us identify effective therapeutic targets. Yet, our insights are limited by the fact that we can on...
The combination of the wealth of genomic and phenotypic datasets to the measurement of the circulating proteome enables a snapshot of real-time biology and important results for determining...
Infectious disease monitoring on Oxford Nanopore Technologies (ONT) platforms offers rapid turnaround times and low cost. Tracking low frequency intra-host variants provides important insigh...
Date: April 14, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CET) Across oncology applications, from research to molecular testing and pharmaceutical development, the ability to identify...
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