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        Applications of Procalcitonin-aided Decision Making for Antibiotic Stewardship in Emergency Care
      • High-throughput CRISPR editing using the Onyx™ platform identifies essential residues in proteins
        High-throughput CRISPR editing using the Onyx™ platform identifies essential residues in proteins
      • A novel automated and simultaneous protein/antibody high-throughput purification platform: AmMag and its reusable Magbeads
        A novel automated and simultaneous protein/antibody high-throughput purification platform: AmMag and its reusable Magbeads
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        Uterine B cell dynamics during pregnancy - Immune regulation of the placenta
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    Robotics and Automation

    Robotics and Automation: The term robotic automation or robotization refer to the automation of industrial and business processes using robots, of various guises. Robotic automation software refers to a class of software products used in that latter, clerical, context.

    Webinars

    • MAY 31, 2018 12:00 PM PDT
      Cas9-Based Genome Engineering
      MAY 31, 2018 12:00 PM PDT
      Cas9-Based Genome Engineering
      I will discuss three novel technologies that our laboratory has developed in recent years. In the first part of the talk, I will describe our work on engineering variants of the RNA-guided en...
      Speaker: Alejandro Chavez, MD, PhD
      Presented at: Lab Automation 2018
      MAY 31, 2018 10:30 AM PDT
      Multi-Tissue Experiments in a Scalable and Automation-Compatible Format
      MAY 31, 2018 10:30 AM PDT
      Multi-Tissue Experiments in a Scalable and Automation-Compatible...
      The next step towards more biomimetic in vitro models is the design of multi-organ devices, which allow for communication of different tissue types. Combining physiologically relevant organ m...
      Speaker: Olivier Frey, PhD
      Presented at: Lab Automation 2018
      MAY 31, 2018 9:00 AM PDT
      Automation of Live-Cell Metabolic Assays with the Seahorse XFe96 Analyzer and Bravo Automated Liquid Handling Platform
      MAY 31, 2018 9:00 AM PDT
      Automation of Live-Cell Metabolic Assays with the Seahorse XFe96...
      Cell-based assays are more biologically relevant than biochemical assays yet significantly more scalable than in vivo experiments.  However, care must be taken in sample preparation to e...
      Speaker: Sarah Burroughs, PhD , Kenda Evans, PhD
      Presented at: Lab Automation 2018Sponsored By: Agilent
      MAY 31, 2018 7:30 AM PDT
      Keynote Presentation: NCATS Automation Capabilities - Where We Are and Where We Are Going
      MAY 31, 2018 7:30 AM PDT
      Keynote Presentation: NCATS Automation Capabilities - Where We...
      Over the years high throughput screening has evolved from monolithic static systems to modular more dynamic platforms.  At NCATS the approach taken has been to optimize our existing lega...
      Speaker: Sam Michael
      Presented at: Lab Automation 2018
      MAY 30, 2018 1:30 PM PDT
      Synthetic Biology - New Tools and Materials for Consumer Industries
      MAY 30, 2018 1:30 PM PDT
      Synthetic Biology - New Tools and Materials for Consumer Industries
      Synthetic biology is a new set of tools and techniques for engineering biology. Its earliest applications were in biotech-related fields like medicine and agriculture, but today it’s be...
      Speaker: Mark Bunger
      Presented at: Lab Automation 2018
      MAY 30, 2018 12:00 PM PDT
      High Throughput Screening Robotics within the UK Centre for Drug Discovery
      MAY 30, 2018 12:00 PM PDT
      High Throughput Screening Robotics within the UK Centre for Drug...
      AstraZeneca has an ambition to create a porous organisation, seamlessly collaborating with external partners. This desire has led to the establishment of the AstraZeneca-MRC UK Centre for Lea...
      Speaker: Mark Wigglesworth
      Presented at: Lab Automation 2018
      MAY 30, 2018 10:30 AM PDT
      Inhibitors of NSD2 Discovered by High-Throughput Screening with a Nucleosome Substrate
      MAY 30, 2018 10:30 AM PDT
      Inhibitors of NSD2 Discovered by High-Throughput Screening with...
      NSD2 catalyzes the mono- and di-methylation of the e-amine of lysine 36 from histone H3, utilizing the methyl donor S-adenosyl-L-methionine. Increased catalytic activity of NSD2, either by ov...
      Speaker: Nathan Coussens, PhD
      Presented at: Lab Automation 2018
      MAY 30, 2018 9:00 AM PDT
      Automation Meets Cell Separation
      MAY 30, 2018 9:00 AM PDT
      Automation Meets Cell Separation
      In this webinar Automation Meets Cell Separation as we will discuss the benefits of automating cell isolation processes in laboratories of variable size and sample throughput, and go into det...
      Speaker: Lotta Raty
      Presented at: Lab Automation 2018Sponsored By: Miltenyi Biotec
      MAY 30, 2018 7:30 AM PDT
      Keynote Presentation: Robotic Automation of Human Cell Culture for Regenerative and Reparative Medicine
      MAY 30, 2018 7:30 AM PDT
      Keynote Presentation: Robotic Automation of Human Cell Culture...
      Growing living human cells in vitro for basic research, drug discovery and reparative/regenerative medicine is challenged by the difficulty in developing methods for reproducibly and cost eff...
      Speaker: Robin Felder, PhD
      Presented at: Lab Automation 2018
      MAY 30, 2018 6:00 AM PDT
      Phenotypic Profiling for Improving Drug Discovery Productivity
      MAY 30, 2018 6:00 AM PDT
      Phenotypic Profiling for Improving Drug Discovery Productivity
      The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
      Speaker: Ellen Berg, PhD
      Presented at: Lab Automation 2018
      MAR 14, 2018 1:30 PM PDT
      Assessing the Role of Prefrontal Cortex in Consciousness Via a New Metric of Functional Connectivity
      MAR 14, 2018 1:30 PM PDT
      Assessing the Role of Prefrontal Cortex in Consciousness Via a...
      How does a low-level sensory representation rise into conscious awareness? What determines whether higher-order cortical areas have access to the representational content in sensory regions?...
      Speaker: Megan Peters, PhD
      Presented at: Neuroscience 2018
      MAR 14, 2018 12:00 PM PDT
      Deciphering the Complexities of Neurodegeneration and Neuroinflammation with Gene Expression Profiling
      MAR 14, 2018 12:00 PM PDT
      Deciphering the Complexities of Neurodegeneration and Neuroinflammation...
      Some of the most significant hurdles faced by neuroscientists in the field of neurodegenerative disease research when seeking to acquire genetic information include sample accessibility, repr...
      Speaker: Kelly Miller, PhD
      Presented at: Neuroscience 2018Sponsored By: NanoString Technologies
      MAR 14, 2018 12:00 PM PDT
      The self-tuning brain: normalizing brain oscillations with neurofeedback
      MAR 14, 2018 12:00 PM PDT
      The self-tuning brain: normalizing brain oscillations with neurofeedback
      Using Hebbian as well as homeostatic models of brain plasticity, the effects of neurofeedback (NFB) are examined from the theoretical perspective of EEG normalization. Within this framework,...
      Speaker: Tomas Ros, PhD
      Presented at: Neuroscience 2018
      MAR 14, 2018 12:00 PM PDT
      Decoding How Clathrin is Transported to Distal Synapses Along Axons
      MAR 14, 2018 12:00 PM PDT
      Decoding How Clathrin is Transported to Distal Synapses Along...
      Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and c...
      Speaker: Archan Ganguly, PhD
      Presented at: Neuroscience 2018
      MAR 14, 2018 10:30 AM PDT
      Studying Sex-Specific Signaling to Understand Male Bias in Neurodevelopmental Disorders
      MAR 14, 2018 10:30 AM PDT
      Studying Sex-Specific Signaling to Understand Male Bias in Neurodevelopmental...
      Since its initial description more than 70 years ago, autism spectrum disorder (ASD) has been diagnosed more frequently in boys. However, we remain unsure of why males are affected in greater...
      Speaker: Chiara Manzini, PhD
      Presented at: Neuroscience 2018
      MAR 14, 2018 10:30 AM PDT
      Investigating the Locus of Conscious Sensory Experience in the Brain
      MAR 14, 2018 10:30 AM PDT
      Investigating the Locus of Conscious Sensory Experience in the...
      Is sensory awareness facilitated by activity in only sensory cortices? For several decades, this has been the dominant viewpoint among many prominent voices in both neuroscience and philosoph...
      Speaker: Brian Odegaard, PhD
      Presented at: Neuroscience 2018
      MAR 14, 2018 10:30 AM PDT
      CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural Cell Mechanisms and Modeling
      MAR 14, 2018 10:30 AM PDT
      CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural...
      CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis.   Even with such powerful technology at hand, sophisticated projects, su...
      Speaker: Jeremy Lehmann
      Presented at: Neuroscience 2018Sponsored By: MilliporeSigma
      MAR 14, 2018 9:00 AM PDT
      3D Dilemma of This Century
      MAR 14, 2018 9:00 AM PDT
      3D Dilemma of This Century
      Most neuropsychiatric diseases involve multifactorial systems characterized by complex interactions among genetic predisposition/resiliency, environmental/social determinants, molecular seque...
      Speaker: Natalie Rasgon, MD, PhD
      Presented at: Neuroscience 2018
      MAR 14, 2018 9:00 AM PDT
      IPSC-Derived Human Neurons: Introduction and Application
      MAR 14, 2018 9:00 AM PDT
      IPSC-Derived Human Neurons: Introduction and Application
      Biomedical research depends on the use of model systems to explore basic biology, probe disease mechanisms, and conduct drug discovery and development. However, results from such systems are...
      Speaker: Michael Hendrickson
      Presented at: Neuroscience 2018Sponsored By: BrainXell
      MAR 14, 2018 7:30 AM PDT
      Keynote Presentation: Ataxia, Dysmetria of Thought, and the Cerebellar Cognitive Affective Syndrome
      MAR 14, 2018 7:30 AM PDT
      Keynote Presentation: Ataxia, Dysmetria of Thought, and the Cerebellar...
      The cerebellum is incorporated into the distributed neural circuits subserving motor control, cognitive processing and the modulation of emotion. This lecture provides an overview of anatomic...
      Speaker: Jeremy Schmahmann, MD
      Presented at: Neuroscience 2018
      MAR 14, 2018 6:00 AM PDT
      Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery of Biologics for Alzheimer's Disease
      MAR 14, 2018 6:00 AM PDT
      Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery...
      98% of small molecules and 100% of large molecules do not cross the blood-brain barrier (BBB). Biologics, including therapeutic antibodies (e.g. anti-amyloid antibodies), have been at the for...
      Speaker: Rachita Sumbria, PhD
      Presented at: Neuroscience 2018
      MAR 14, 2018 6:00 AM PDT
      Mapping Cerebellum-to-Forebrain Connectivity Using Optogenetics and Functional Magnetic Resonance Imaging
      MAR 14, 2018 6:00 AM PDT
      Mapping Cerebellum-to-Forebrain Connectivity Using Optogenetics...
      Complex animal behavior is produced by dynamic interactions between discrete regions of the brain. As such, defining functional connections between brain regions is critical in gaining a full...
      Speaker: Paul Mathews, PhD
      Presented at: Neuroscience 2018
      MAR 14, 2018 6:00 AM PDT
      Speech Graphs as a Tool for Psychiatric Diagnosis: A Physicist's Walk into Computational Psychiatry
      MAR 14, 2018 6:00 AM PDT
      Speech Graphs as a Tool for Psychiatric Diagnosis: A Physicist's...
      Psychiatric diagnosis is inherently difficult, due to the lack of clear biomarkers or any other objective assessment. Although quantitative, the psychometric scales employed during the psychi...
      Speaker: Mauro Copelli, PhD
      Presented at: Neuroscience 2018
      Beyond Automated iPSC reprogramming: applications for a fully automated cell culture system for pluripotent stem cell research
      Beyond Automated iPSC reprogramming: applications for a fully...
      The use of pluripotent stem cells is dramatically altering the R&D landscape, providing new insights into both the basic biology of disease progression and novel cell types for pharmaceut...
      Speaker: Daniel Paull
      Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
    MAY 31, 2018 12:00 PM PDT
    Cas9-Based Genome Engineering
    MAY 31, 2018 12:00 PM PDT
    Cas9-Based Genome Engineering
    I will discuss three novel technologies that our laboratory has developed in recent years. In the first part of the talk, I will describe our work on engineering variants of the RNA-guided en...
    Speaker: Alejandro Chavez, MD, PhD
    Presented at: Lab Automation 2018
    MAY 31, 2018 10:30 AM PDT
    Multi-Tissue Experiments in a Scalable and Automation-Compatible Format
    MAY 31, 2018 10:30 AM PDT
    Multi-Tissue Experiments in a Scalable and Automation-Compatible...
    The next step towards more biomimetic in vitro models is the design of multi-organ devices, which allow for communication of different tissue types. Combining physiologically relevant organ m...
    Speaker: Olivier Frey, PhD
    Presented at: Lab Automation 2018
    MAY 31, 2018 9:00 AM PDT
    Automation of Live-Cell Metabolic Assays with the Seahorse XFe96 Analyzer and Bravo Automated Liquid Handling Platform
    MAY 31, 2018 9:00 AM PDT
    Automation of Live-Cell Metabolic Assays with the Seahorse XFe96...
    Cell-based assays are more biologically relevant than biochemical assays yet significantly more scalable than in vivo experiments.  However, care must be taken in sample preparation to e...
    Speaker: Sarah Burroughs, PhD , Kenda Evans, PhD
    Presented at: Lab Automation 2018Sponsored By: Agilent
    MAY 31, 2018 7:30 AM PDT
    Keynote Presentation: NCATS Automation Capabilities - Where We Are and Where We Are Going
    MAY 31, 2018 7:30 AM PDT
    Keynote Presentation: NCATS Automation Capabilities - Where We...
    Over the years high throughput screening has evolved from monolithic static systems to modular more dynamic platforms.  At NCATS the approach taken has been to optimize our existing lega...
    Speaker: Sam Michael
    Presented at: Lab Automation 2018
    MAY 30, 2018 1:30 PM PDT
    Synthetic Biology - New Tools and Materials for Consumer Industries
    MAY 30, 2018 1:30 PM PDT
    Synthetic Biology - New Tools and Materials for Consumer Industries
    Synthetic biology is a new set of tools and techniques for engineering biology. Its earliest applications were in biotech-related fields like medicine and agriculture, but today it’s be...
    Speaker: Mark Bunger
    Presented at: Lab Automation 2018
     
     
  • MAY 30, 2018 12:00 PM PDT
    High Throughput Screening Robotics within the UK Centre for Drug Discovery
    MAY 30, 2018 12:00 PM PDT
    High Throughput Screening Robotics within the UK Centre for Drug...
    AstraZeneca has an ambition to create a porous organisation, seamlessly collaborating with external partners. This desire has led to the establishment of the AstraZeneca-MRC UK Centre for Lea...
    Speaker: Mark Wigglesworth
    Presented at: Lab Automation 2018
    MAY 30, 2018 10:30 AM PDT
    Inhibitors of NSD2 Discovered by High-Throughput Screening with a Nucleosome Substrate
    MAY 30, 2018 10:30 AM PDT
    Inhibitors of NSD2 Discovered by High-Throughput Screening with...
    NSD2 catalyzes the mono- and di-methylation of the e-amine of lysine 36 from histone H3, utilizing the methyl donor S-adenosyl-L-methionine. Increased catalytic activity of NSD2, either by ov...
    Speaker: Nathan Coussens, PhD
    Presented at: Lab Automation 2018
    MAY 30, 2018 9:00 AM PDT
    Automation Meets Cell Separation
    MAY 30, 2018 9:00 AM PDT
    Automation Meets Cell Separation
    In this webinar Automation Meets Cell Separation as we will discuss the benefits of automating cell isolation processes in laboratories of variable size and sample throughput, and go into det...
    Speaker: Lotta Raty
    Presented at: Lab Automation 2018Sponsored By: Miltenyi Biotec
    MAY 30, 2018 7:30 AM PDT
    Keynote Presentation: Robotic Automation of Human Cell Culture for Regenerative and Reparative Medicine
    MAY 30, 2018 7:30 AM PDT
    Keynote Presentation: Robotic Automation of Human Cell Culture...
    Growing living human cells in vitro for basic research, drug discovery and reparative/regenerative medicine is challenged by the difficulty in developing methods for reproducibly and cost eff...
    Speaker: Robin Felder, PhD
    Presented at: Lab Automation 2018
    MAY 30, 2018 6:00 AM PDT
    Phenotypic Profiling for Improving Drug Discovery Productivity
    MAY 30, 2018 6:00 AM PDT
    Phenotypic Profiling for Improving Drug Discovery Productivity
    The pharmaceutical industry’s productivity crisis is well known with >90% of drug candidates failing in clinical testing, primarily due to unexpected toxicity or lack of efficacy. &n...
    Speaker: Ellen Berg, PhD
    Presented at: Lab Automation 2018
     
     
  • MAR 14, 2018 1:30 PM PDT
    Assessing the Role of Prefrontal Cortex in Consciousness Via a New Metric of Functional Connectivity
    MAR 14, 2018 1:30 PM PDT
    Assessing the Role of Prefrontal Cortex in Consciousness Via a...
    How does a low-level sensory representation rise into conscious awareness? What determines whether higher-order cortical areas have access to the representational content in sensory regions?...
    Speaker: Megan Peters, PhD
    Presented at: Neuroscience 2018
    MAR 14, 2018 12:00 PM PDT
    Deciphering the Complexities of Neurodegeneration and Neuroinflammation with Gene Expression Profiling
    MAR 14, 2018 12:00 PM PDT
    Deciphering the Complexities of Neurodegeneration and Neuroinflammation...
    Some of the most significant hurdles faced by neuroscientists in the field of neurodegenerative disease research when seeking to acquire genetic information include sample accessibility, repr...
    Speaker: Kelly Miller, PhD
    Presented at: Neuroscience 2018Sponsored By: NanoString Technologies
    MAR 14, 2018 12:00 PM PDT
    The self-tuning brain: normalizing brain oscillations with neurofeedback
    MAR 14, 2018 12:00 PM PDT
    The self-tuning brain: normalizing brain oscillations with neurofeedback
    Using Hebbian as well as homeostatic models of brain plasticity, the effects of neurofeedback (NFB) are examined from the theoretical perspective of EEG normalization. Within this framework,...
    Speaker: Tomas Ros, PhD
    Presented at: Neuroscience 2018
    MAR 14, 2018 12:00 PM PDT
    Decoding How Clathrin is Transported to Distal Synapses Along Axons
    MAR 14, 2018 12:00 PM PDT
    Decoding How Clathrin is Transported to Distal Synapses Along...
    Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and c...
    Speaker: Archan Ganguly, PhD
    Presented at: Neuroscience 2018
    MAR 14, 2018 10:30 AM PDT
    Studying Sex-Specific Signaling to Understand Male Bias in Neurodevelopmental Disorders
    MAR 14, 2018 10:30 AM PDT
    Studying Sex-Specific Signaling to Understand Male Bias in Neurodevelopmental...
    Since its initial description more than 70 years ago, autism spectrum disorder (ASD) has been diagnosed more frequently in boys. However, we remain unsure of why males are affected in greater...
    Speaker: Chiara Manzini, PhD
    Presented at: Neuroscience 2018
     
     
  • MAR 14, 2018 10:30 AM PDT
    Investigating the Locus of Conscious Sensory Experience in the Brain
    MAR 14, 2018 10:30 AM PDT
    Investigating the Locus of Conscious Sensory Experience in the...
    Is sensory awareness facilitated by activity in only sensory cortices? For several decades, this has been the dominant viewpoint among many prominent voices in both neuroscience and philosoph...
    Speaker: Brian Odegaard, PhD
    Presented at: Neuroscience 2018
    MAR 14, 2018 10:30 AM PDT
    CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural Cell Mechanisms and Modeling
    MAR 14, 2018 10:30 AM PDT
    CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural...
    CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis.   Even with such powerful technology at hand, sophisticated projects, su...
    Speaker: Jeremy Lehmann
    Presented at: Neuroscience 2018Sponsored By: MilliporeSigma
    MAR 14, 2018 9:00 AM PDT
    3D Dilemma of This Century
    MAR 14, 2018 9:00 AM PDT
    3D Dilemma of This Century
    Most neuropsychiatric diseases involve multifactorial systems characterized by complex interactions among genetic predisposition/resiliency, environmental/social determinants, molecular seque...
    Speaker: Natalie Rasgon, MD, PhD
    Presented at: Neuroscience 2018
    MAR 14, 2018 9:00 AM PDT
    IPSC-Derived Human Neurons: Introduction and Application
    MAR 14, 2018 9:00 AM PDT
    IPSC-Derived Human Neurons: Introduction and Application
    Biomedical research depends on the use of model systems to explore basic biology, probe disease mechanisms, and conduct drug discovery and development. However, results from such systems are...
    Speaker: Michael Hendrickson
    Presented at: Neuroscience 2018Sponsored By: BrainXell
    MAR 14, 2018 7:30 AM PDT
    Keynote Presentation: Ataxia, Dysmetria of Thought, and the Cerebellar Cognitive Affective Syndrome
    MAR 14, 2018 7:30 AM PDT
    Keynote Presentation: Ataxia, Dysmetria of Thought, and the Cerebellar...
    The cerebellum is incorporated into the distributed neural circuits subserving motor control, cognitive processing and the modulation of emotion. This lecture provides an overview of anatomic...
    Speaker: Jeremy Schmahmann, MD
    Presented at: Neuroscience 2018
     
     
  • MAR 14, 2018 6:00 AM PDT
    Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery of Biologics for Alzheimer's Disease
    MAR 14, 2018 6:00 AM PDT
    Targeting the Blood-Brain Barrier Transferrin Receptor for Delivery...
    98% of small molecules and 100% of large molecules do not cross the blood-brain barrier (BBB). Biologics, including therapeutic antibodies (e.g. anti-amyloid antibodies), have been at the for...
    Speaker: Rachita Sumbria, PhD
    Presented at: Neuroscience 2018
    MAR 14, 2018 6:00 AM PDT
    Mapping Cerebellum-to-Forebrain Connectivity Using Optogenetics and Functional Magnetic Resonance Imaging
    MAR 14, 2018 6:00 AM PDT
    Mapping Cerebellum-to-Forebrain Connectivity Using Optogenetics...
    Complex animal behavior is produced by dynamic interactions between discrete regions of the brain. As such, defining functional connections between brain regions is critical in gaining a full...
    Speaker: Paul Mathews, PhD
    Presented at: Neuroscience 2018
    MAR 14, 2018 6:00 AM PDT
    Speech Graphs as a Tool for Psychiatric Diagnosis: A Physicist's Walk into Computational Psychiatry
    MAR 14, 2018 6:00 AM PDT
    Speech Graphs as a Tool for Psychiatric Diagnosis: A Physicist's...
    Psychiatric diagnosis is inherently difficult, due to the lack of clear biomarkers or any other objective assessment. Although quantitative, the psychometric scales employed during the psychi...
    Speaker: Mauro Copelli, PhD
    Presented at: Neuroscience 2018
    Beyond Automated iPSC reprogramming: applications for a fully automated cell culture system for pluripotent stem cell research
    Beyond Automated iPSC reprogramming: applications for a fully...
    The use of pluripotent stem cells is dramatically altering the R&D landscape, providing new insights into both the basic biology of disease progression and novel cell types for pharmaceut...
    Speaker: Daniel Paull
    Presented at: 6th annual 24 Hours of Stem Cells™ virtual event
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