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    Single cell biopsy

    A single cell biopsy can assess what genes are expressed in a specific cell. This technique can be used to investigate cell to cell differences throughout a type of tissue.

    Webinars

    • APR 15, 2020 | 9:00 AM
      Single-cell multi-omics: DNA methylation and 3D genome
      Single-cell multi-omics: DNA methylation and 3D genome
      DATE: April 15, 2020 TIME: 9:00am PT, 12:00pm ET We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC...
      Speaker: Yaping Liu, Ph.D.
      Sponsored By: Zymo Research
      9 3
      OCT 10, 2019 | 12:00 PM
      Tumor Mutation Burden: Challenges and opportunities of measuring and interpreting tumor mutational burden for patient care
      Tumor Mutation Burden: Challenges and opportunities of measuring...
      Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
      Speaker: Ravindra Kolhe, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: QIAGEN
      1
      OCT 10, 2019 | 9:00 AM
      Dynamic evolution of unstable genomes: insights from in vitro experiments and cancer genome analysis
      Dynamic evolution of unstable genomes: insights from in vitro...
      Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
      Speaker: Cheng-Zhong Zhang, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      1
      OCT 09, 2019 | 10:30 AM
      A practical guide for multiplexed ion beam imaging to reveal tumor immunobiology
      A practical guide for multiplexed ion beam imaging to reveal tumor...
      MIBI is a powerful platform for identifying and analyzing multiple antigens in formalin-fixed paraffin-embedded tissues. This multiplexed methodology permits the identification of 40+ protein...
      Speaker: Selena Ferrian
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
      Sponsored By: IONpath
      6
      APR 10, 2019 | 6:00 AM
      Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
      Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
      Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. We combine the RNA- targeting CRISPR effector Cas13 with...
      Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2019
      6
      FEB 27, 2019 | 10:30 AM
      The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
      The Current State-of-the-Art Tissue Expression Analysis Platform...
      Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
      Speaker: Christopher Bunker, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: Advanced Cell Diagnostics
      1
      OCT 11, 2018 | 1:30 PM
      Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in Cancer
      Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in...
      Recent work has identified epigenomic features of distal regulatory elements to be dynamic and defining indicators of cellular specification and transformation. Of particular relevance is our...
      Speaker: Martin Hirst, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 6:00 AM
      Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
      Revealing the Hidden Landscape of Structural Variants in Cancer...
      PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
      Speaker: Jonas Korlach, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 10:30 AM
      Microbiome Signatures in Gynecologic Cancers
      Microbiome Signatures in Gynecologic Cancers
      The microbiome signatures in the context of gynecologic cancers (endometrial and ovarian) and the potential for their clinical use will be discussed. The use of microfluidic technologies to i...
      Speaker: Marina Walther-Antonio, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      3
      OCT 10, 2018 | 9:00 AM
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
      In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
      Speaker: Paul Sondel, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      APR 06, 2018 | 9:00 AM
      Multiplex Immunofluorescence Profiling of Tumor Biopsies Using UltraPlex mxIF Technology
      Multiplex Immunofluorescence Profiling of Tumor Biopsies Using...
      DATE: April 4, 2018TIME: 09:00am PDT, 12:00pm CEST Multiplex is the ability to characterize three or more biomarkers on a single tissue section. The technique enables the combi...
      Speaker: Helen Snyder, PhD , Marie-Louise Loupart, PhD
      Sponsored By: Leica Biosystems
      8
      OCT 12, 2017 | 12:00 PM
      Live-single-cell phenotypic biomarkers measured from primary biopsy samples:  An emerging class of biomarkers toward the development of precision diagnostics and the discovery and development
      Live-single-cell phenotypic biomarkers measured from primary biopsy...
      The promise of precision and personalized medicine is rooted in accurate, highly sensitive, and specific disease biomarkers. This is particularly true for cancer-a disease characterized by ma...
      Speaker: Ashok Chander, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      FEB 22, 2017 | 6:00 AM
      Mate-pair next generation sequencing as a powerful clinical tool for the characterization of cancer
      Mate-pair next generation sequencing as a powerful clinical tool...
      Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
      Speaker: David Smith, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      4
      JAN 19, 2017 | 8:00 AM
      Webinar: Detecting meaningful mutations from liquid biopsies by Anchored Multiplex PCR
      Webinar: Detecting meaningful mutations from liquid biopsies by...
      DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
      Speaker: Josh Stahl , Jonathan Doose
      Sponsored By: ArcherDX, ArcherDX
      9
      NOV 01, 2016 | 8:00 AM
      Development of selection strategies for Homologous Recombination Deficient (HRD) patients utilizing a Liquid Biopsy
      Development of selection strategies for Homologous Recombination...
      DATE: November 1, 2016 TIME: 8:00AM PT, 11:00AM ET Metastatic cancer is an evolving, heterogeneous disease that becomes more complex over time through the selection of sub-clonal tumor po...
      Speaker: Mark Landers
      Sponsored By: Epic Sciences, Epic Sciences , Epic Sciences
      4
      APR 06, 2016 | 6:00 AM
      EFIRM Liquid Biopsy
      EFIRM Liquid Biopsy
      The advent of personalized medicine employing molecular targeted therapies has markedly changed the treatment of cancer in the past 10 years. Although tumor tissue biopsy-based genotyping is...
      Speaker: David Wong DMD, DMSc
      Presented at: Molecular Diagnostics Virtual Event Series 2016
      5 1
      SEP 30, 2015 | 1:30 PM
      SuperSelective Primers for the Multiplex Quantitation of Rare Mutant Sequences Associated with Cancer
      SuperSelective Primers for the Multiplex Quantitation of Rare...
      A major goal of molecular diagnostics is to find a sensitive and specific means for detecting and quantifying DNA fragments from rare cancer cells (by virtue of an identifying somatic mutatio...
      Speaker: Fred Kramer, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      JUN 17, 2015 | 8:00 AM
      Real-Time Profiling of Tumor Heterogeneity in Metastatic Disease
      Real-Time Profiling of Tumor Heterogeneity in Metastatic Disease
      DATE: June 17th, 2015TIME: 8am Pacific time, 11am Eastern timeSpatial heterogeneity of tumors has been identified within and between metastatic lesions and can be visualized wit...
      Speaker: Mark Landers
      Sponsored By: Epic Sciences, Epic Sciences
      15 2
      MAY 13, 2015 | 6:00 AM
      Predictive Gene Signatures: Molecular Markers Distinguishing Colon Adenomatous Polyp and Carcinoma
      Predictive Gene Signatures: Molecular Markers Distinguishing Colon...
      Cancers exhibit abnormal molecular signatures associated with disease initiation and progression. Molecular signatures could improve cancer screening, detection, drug development and selectio...
      Speaker: Janice Drew, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      0
    APR 15, 2020 | 9:00 AM
    Single-cell multi-omics: DNA methylation and 3D genome
    Single-cell multi-omics: DNA methylation and 3D genome
    DATE: April 15, 2020 TIME: 9:00am PT, 12:00pm ET We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC...
    Speaker: Yaping Liu, Ph.D.
    Sponsored By: Zymo Research
    9 3
    OCT 10, 2019 | 12:00 PM
    Tumor Mutation Burden: Challenges and opportunities of measuring and interpreting tumor mutational burden for patient care
    Tumor Mutation Burden: Challenges and opportunities of measuring...
    Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
    Speaker: Ravindra Kolhe, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: QIAGEN
    1
    OCT 10, 2019 | 9:00 AM
    Dynamic evolution of unstable genomes: insights from in vitro experiments and cancer genome analysis
    Dynamic evolution of unstable genomes: insights from in vitro...
    Copy-number alterations and chromosomal translocations are widespread in cancer and frequently causing oncogenic mutations that drive tumorigenesis and therapy resistance. Despite their preva...
    Speaker: Cheng-Zhong Zhang, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    1
    OCT 09, 2019 | 10:30 AM
    A practical guide for multiplexed ion beam imaging to reveal tumor immunobiology
    A practical guide for multiplexed ion beam imaging to reveal tumor...
    MIBI is a powerful platform for identifying and analyzing multiple antigens in formalin-fixed paraffin-embedded tissues. This multiplexed methodology permits the identification of 40+ protein...
    Speaker: Selena Ferrian
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019
    Sponsored By: IONpath
    6
    APR 10, 2019 | 6:00 AM
    Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
    Keynote Presentation: Nucleic Acid Detection with CRISPR Diagnostics
    Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. We combine the RNA- targeting CRISPR effector Cas13 with...
    Speaker: Omar Abudayyeh, PhD , Jonathan Gootenberg, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2019
    6
     
     
  • FEB 27, 2019 | 10:30 AM
    The Current State-of-the-Art Tissue Expression Analysis Platform for Detection & Quantification of Target & Biomarker mRNAs, Splice Variants and Mutations in Preclinical & Clinical Tissues
    The Current State-of-the-Art Tissue Expression Analysis Platform...
    Advanced Cell Diagnostics’ RNAscope products and assay services are utilized widely for tissue-based gene expression analysis in early target validation, preclinical animal efficacy and...
    Speaker: Christopher Bunker, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: Advanced Cell Diagnostics
    1
    OCT 11, 2018 | 1:30 PM
    Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in Cancer
    Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in...
    Recent work has identified epigenomic features of distal regulatory elements to be dynamic and defining indicators of cellular specification and transformation. Of particular relevance is our...
    Speaker: Martin Hirst, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 6:00 AM
    Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
    Revealing the Hidden Landscape of Structural Variants in Cancer...
    PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
    Speaker: Jonas Korlach, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 10:30 AM
    Microbiome Signatures in Gynecologic Cancers
    Microbiome Signatures in Gynecologic Cancers
    The microbiome signatures in the context of gynecologic cancers (endometrial and ovarian) and the potential for their clinical use will be discussed. The use of microfluidic technologies to i...
    Speaker: Marina Walther-Antonio, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    3
    OCT 10, 2018 | 9:00 AM
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
    In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
    Speaker: Paul Sondel, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
     
     
  • APR 06, 2018 | 9:00 AM
    Multiplex Immunofluorescence Profiling of Tumor Biopsies Using UltraPlex mxIF Technology
    Multiplex Immunofluorescence Profiling of Tumor Biopsies Using...
    DATE: April 4, 2018TIME: 09:00am PDT, 12:00pm CEST Multiplex is the ability to characterize three or more biomarkers on a single tissue section. The technique enables the combi...
    Speaker: Helen Snyder, PhD , Marie-Louise Loupart, PhD
    Sponsored By: Leica Biosystems
    8
    OCT 12, 2017 | 12:00 PM
    Live-single-cell phenotypic biomarkers measured from primary biopsy samples:  An emerging class of biomarkers toward the development of precision diagnostics and the discovery and development
    Live-single-cell phenotypic biomarkers measured from primary biopsy...
    The promise of precision and personalized medicine is rooted in accurate, highly sensitive, and specific disease biomarkers. This is particularly true for cancer-a disease characterized by ma...
    Speaker: Ashok Chander, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
    FEB 22, 2017 | 6:00 AM
    Mate-pair next generation sequencing as a powerful clinical tool for the characterization of cancer
    Mate-pair next generation sequencing as a powerful clinical tool...
    Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
    Speaker: David Smith, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    4
    JAN 19, 2017 | 8:00 AM
    Webinar: Detecting meaningful mutations from liquid biopsies by Anchored Multiplex PCR
    Webinar: Detecting meaningful mutations from liquid biopsies by...
    DATE: January 19th, 2017TIME: 8:00AM PT, 11:00AM ETLiquid biopsies have the potential to be a less invasive method than traditional biopsies to detect advanced solid tumor mutational st...
    Speaker: Josh Stahl , Jonathan Doose
    Sponsored By: ArcherDX, ArcherDX
    9
    NOV 01, 2016 | 8:00 AM
    Development of selection strategies for Homologous Recombination Deficient (HRD) patients utilizing a Liquid Biopsy
    Development of selection strategies for Homologous Recombination...
    DATE: November 1, 2016 TIME: 8:00AM PT, 11:00AM ET Metastatic cancer is an evolving, heterogeneous disease that becomes more complex over time through the selection of sub-clonal tumor po...
    Speaker: Mark Landers
    Sponsored By: Epic Sciences, Epic Sciences , Epic Sciences
    4
     
     
  • APR 06, 2016 | 6:00 AM
    EFIRM Liquid Biopsy
    EFIRM Liquid Biopsy
    The advent of personalized medicine employing molecular targeted therapies has markedly changed the treatment of cancer in the past 10 years. Although tumor tissue biopsy-based genotyping is...
    Speaker: David Wong DMD, DMSc
    Presented at: Molecular Diagnostics Virtual Event Series 2016
    5 1
    SEP 30, 2015 | 1:30 PM
    SuperSelective Primers for the Multiplex Quantitation of Rare Mutant Sequences Associated with Cancer
    SuperSelective Primers for the Multiplex Quantitation of Rare...
    A major goal of molecular diagnostics is to find a sensitive and specific means for detecting and quantifying DNA fragments from rare cancer cells (by virtue of an identifying somatic mutatio...
    Speaker: Fred Kramer, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    JUN 17, 2015 | 8:00 AM
    Real-Time Profiling of Tumor Heterogeneity in Metastatic Disease
    Real-Time Profiling of Tumor Heterogeneity in Metastatic Disease
    DATE: June 17th, 2015TIME: 8am Pacific time, 11am Eastern timeSpatial heterogeneity of tumors has been identified within and between metastatic lesions and can be visualized wit...
    Speaker: Mark Landers
    Sponsored By: Epic Sciences, Epic Sciences
    15 2
    MAY 13, 2015 | 6:00 AM
    Predictive Gene Signatures: Molecular Markers Distinguishing Colon Adenomatous Polyp and Carcinoma
    Predictive Gene Signatures: Molecular Markers Distinguishing Colon...
    Cancers exhibit abnormal molecular signatures associated with disease initiation and progression. Molecular signatures could improve cancer screening, detection, drug development and selectio...
    Speaker: Janice Drew, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    0
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