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    Single cell profiling

    Single cell profiling is a scientific technique to evaluate all components of a single cell. Single cell profiling analyzes the sequence of DNA in a cell providing information on factors including surface protein expression and antigen specificity. Data learned from single cell profiling can be used to detect diseases or provide personalized treatments.

    Webinars

    • JUL 07, 2020 | 11:00 AM
      Comprehensive landscape of the tumor microenvironment analyzed with CyTOF® technology
      Comprehensive landscape of the tumor microenvironment analyzed...
      Immune escape mechanisms such as the induction/recruitment of immunosuppressive cells and the increased expression of various immunosuppressive molecules including PD-1/PD-1 ligands are esse...
      Speaker: Hiroyoshi Nishikawa, MD, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      2
      JUL 07, 2020 | 7:30 AM
      Deciphering T cell heterogeneity in humans through analysis of antigen-specificity
      Deciphering T cell heterogeneity in humans through analysis of...
      In line with the role of T cells as critical mediators of the adaptive immune response, recombinational and junctional diversity of the T cell receptor makes each T cell almost entirely uniq...
      Speaker: Evan Newell, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      2
      JUL 07, 2020 | 6:00 AM
      Single-cell mapping of human brain cancer reveals tumor-driven education of tumor-associated leukocytes
      Single-cell mapping of human brain cancer reveals tumor-driven...
      Brain malignancies can either originate from within the CNS (gliomas) or invade from other locations in the body (metastases). A highly immunosuppressive tumor microenvironment (TME) influen...
      Speaker: Burkhard Becher, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      JUL 01, 2020 | 12:15 PM
      Simplify your journey of molecular profiling with single day NGS
      Simplify your journey of molecular profiling with single day NGS
      Learn about how the new Ion Torrent Genexus System is addressing key challenges to next-generation sequencing (NGS) implementation, like hands-on time, time-to-result, user expertise, and af...
      Speaker: Jon Sherlock, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
      JUN 03, 2020 | 4:00 PM
      Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢ Technology
      Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢...
      The RNAscope in situ hybridization technology allows high sensitivity, specificity and spatial resolution providing pivotal single-cell gene expression information to gain better insights in...
      Speaker: Anushka Dikshit, PhD
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: Advanced Cell Diagnostics
      0
      MAY 20, 2020 | 12:00 AM
      Single-cell Genomics Tools for better understanding and treatment of Human Disease
      Single-cell Genomics Tools for better understanding and treatment...
      The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
      Speaker: Anindita Basu, PhD
      Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
      2
      MAY 19, 2020 | 1:45 PM
      Cancer Transcriptome Atlas with NGS Readout - The essential tool for spatial genomics in oncology
      Cancer Transcriptome Atlas with NGS Readout - The essential tool...
      While many technologies focus on either exploring the spatial context of a handful of targets, or expression patterns of hundreds or thousands of targets in bulk samples or dissociated singl...
      Speaker: Kit Fuhrman, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 19, 2020 | 1:45 PM
      Tumor Signaling 360 Panel: A 360° View of Altered Signaling Pathways in Cancer
      Tumor Signaling 360 Panel: A 360° View of Altered Signaling Pathways...
      Targeted therapies for cancer are increasingly being developed as an alternative for, and in addition to, immunotherapy. Altered tumor signaling can be exploited to single-out cancer cells f...
      Speaker: Erin Piazza, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      3
      MAY 19, 2020 | 1:15 PM
      Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢ Technology
      Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢...
      The RNAscope in situ hybridization technology allows high sensitivity, specificity and spatial resolution providing pivotal single-cell gene expression information to gain better insights in...
      Speaker: Anushka Dikshit, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      3
      MAY 19, 2020 | 11:45 AM
      Single-nucleus and Spatial Transcriptomics of Archival Pancreatic Ductal Adenocarcinoma after Neoadjuvant Treatment
      Single-nucleus and Spatial Transcriptomics of Archival Pancreatic...
      Pancreatic ductal adenocarcinoma (PDAC) remains a treatment-refractory disease and existing molecular subtypes do not inform clinical decisions. Previously-identified bulk transcriptomic sub...
      Speaker: William L. Hwang, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 19, 2020 | 11:15 AM
      Digital Spatial Mapping of the Immune Landscape of Triple Negative Breast Cancer Reveals Novel Features of Immune-tumor Cell Interaction
      Digital Spatial Mapping of the Immune Landscape of Triple Negative...
      Background: Growing evidence supports the critical role of preexisting immune response in triple negative breast cancer (TNBC). However, there are limitations with current evaluation approac...
      Speaker: E. Aubrey Thompson, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 14, 2020 | 2:40 PM
      Oncomine Precision Assay on Ion Torrent Genexus System for liquid biopsy sample
      Oncomine Precision Assay on Ion Torrent Genexus System for liquid...
      Molecular profiling is key in precision oncology research and whilst the tissue testing has become a routine, liquid biopsy might provide a non-invasive alternative when tissue biopsy is ina...
      Speaker: Siew-Kee (Amanda) Low, PhD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      8
      MAY 14, 2020 | 2:40 PM
      Oncomine Precision Assay on Ion Torrent Genexus System for liquid biopsy sample
      Oncomine Precision Assay on Ion Torrent Genexus System for liquid...
      The development of molecular targeted therapy is one of the breakthroughs in oncology field. Molecular profiling of the tumor becomes mandatory in the routine clinical practice to select the...
      Speaker: Siew-Kee (Amanda) Low, PhD
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      APR 24, 2020 | 9:00 AM
      Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs) with the CODEX® Platform
      Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs)...
      DATE: April 24, 2020 TIME: 9:00am PT, 12:00pm ET Single-cell analysis of cell suspensions is increasingly important in studies of infectious diseases, cancer and autoimmune disorders, given...
      Speaker: Jon Mulholland, MS , Anum Khan, PhD , Oliver Braubach, Ph.D.
      Sponsored By: Akoya Biosciences
      6
      APR 23, 2020 | 9:00 AM
      Keynote Presentation: Individualized Health
      Keynote Presentation: Individualized Health
      Learning Objectives: 1. What is wrong with healthcare today 2. What kinds of omics and wearables data can be used to best predict disease risk and manage health...
      Speaker: Michael Snyder, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 22, 2020 | 12:00 AM
      Precision Infectious Disease Diagnostics Using Next-Generation Sequencing and AI
      Precision Infectious Disease Diagnostics Using Next-Generation...
      As the spread of infectious diseases, current pandemic, and growing antimicrobial resistance (AMR) continues globally, next-generation sequencing (NGS) and specifically metagenomics became a...
      Speaker: Dorottya Nagy-Szakal, MD PhD
      Presented at: Genetics Week Virtual Event Series 2020
      2
      APR 21, 2020 | 1:30 PM
      Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
      Spatially Resolved Molecular Investigation of Triple Negative...
      Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
      Speaker: Dina Finan, PhD , Stephen Williams, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 21, 2020 | 12:00 PM
      SNVs to Large Structural Variation: Capturing nucleotide through inter-chromosomal variants through a powerful three-dimensional data type
      SNVs to Large Structural Variation: Capturing nucleotide through...
      Within the clinical arena, the oncology community has led the way in the early adoption of next generation sequencing. NGS is in widespread use in clinical cancer research and is now beginni...
      Speaker: Cory Padilla, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 21, 2020 | 10:30 AM
      Optimizing human karyomapping to phase single lgene defects with improved DNA amplification
      Optimizing human karyomapping to phase single lgene defects with...
      Karyomapping, a technique for preimplantation genetic diagnosis (PGD) of single gene disorders, involves using very few or single cells, and comes with challenges due to limited amounts of s...
      Speaker: Samuel Rulli, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      1
      APR 21, 2020 | 12:00 AM
      Single Cell Multi-omics: Solving the Jigsaw
      Single Cell Multi-omics: Solving the Jigsaw
      Since the introduction of single cell sequencing techniques to the genomics community, interest in its use has grown exponentially and the number of single cell publications has exploded. Th...
      Speaker: Ivan Lukić, MD, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 21, 2020 | 12:00 AM
      Single cell gene expression: new insights through the lens of full length mRNA isoform resolution
      Single cell gene expression: new insights through the lens of...
      Single cell RNA sequencing (scRNA-seq) emerged to characterize gene expression differences between individual cells, allowing a higher resolution look at mRNA abundance than bulk RNA- seq. H...
      Speaker: Jason Underwood, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      MAR 17, 2020 | 8:00 AM
      Multiplexing on Mouse tissue using Cell Signaling Technology antibodies and OPAL IHC method
      Multiplexing on Mouse tissue using Cell Signaling Technology antibodies...
      DATE: March 17, 2020 TIME: 8:00am PT, 11:00am PT Cell Signaling Technology: The determination of target specificity in immunohistochemical analysis requires multiple validation steps. This w...
      Speaker: Bill Kennedy , Christopher Grange
      Sponsored By: Akoya Biosciences, Cell Signaling Technology
      9
      DEC 17, 2019 | 8:00 AM
      Single-Cell Phosphoprotein Analysis with CyTOF: From Training to Immuno-Oncology Clinical Research
      Single-Cell Phosphoprotein Analysis with CyTOF: From Training...
      DATE: December 17, 2019TIME: 8:00am PSTMass cytometry instruments simultaneously measure >50 cellular features, with a typical experiment including millions of cells. Dysregulated...
      Speaker: Jonathan Irish, PhD , Caroline E. Roe, BS
      Sponsored By: Standard BioTools
      7 2
      DEC 05, 2019 | 9:00 AM
      Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
      Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
      DATE: December 5, 2019TIME: 9:00am PST, 12:00pm EST Characterization of the spatial distribution and abundance of proteins and mRNAs with morphological context within tissues e...
      Speaker: Mathias Holpert, PhD , Traci DeGeer, BS, HT (ASCP) HTL, QIHC
      Sponsored By: Leica Biosystems, NanoString Technologies
      8
    JUL 07, 2020 | 11:00 AM
    Comprehensive landscape of the tumor microenvironment analyzed with CyTOF® technology
    Comprehensive landscape of the tumor microenvironment analyzed...
    Immune escape mechanisms such as the induction/recruitment of immunosuppressive cells and the increased expression of various immunosuppressive molecules including PD-1/PD-1 ligands are esse...
    Speaker: Hiroyoshi Nishikawa, MD, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    2
    JUL 07, 2020 | 7:30 AM
    Deciphering T cell heterogeneity in humans through analysis of antigen-specificity
    Deciphering T cell heterogeneity in humans through analysis of...
    In line with the role of T cells as critical mediators of the adaptive immune response, recombinational and junctional diversity of the T cell receptor makes each T cell almost entirely uniq...
    Speaker: Evan Newell, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    2
    JUL 07, 2020 | 6:00 AM
    Single-cell mapping of human brain cancer reveals tumor-driven education of tumor-associated leukocytes
    Single-cell mapping of human brain cancer reveals tumor-driven...
    Brain malignancies can either originate from within the CNS (gliomas) or invade from other locations in the body (metastases). A highly immunosuppressive tumor microenvironment (TME) influen...
    Speaker: Burkhard Becher, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    1
    JUL 01, 2020 | 12:15 PM
    Simplify your journey of molecular profiling with single day NGS
    Simplify your journey of molecular profiling with single day NGS
    Learn about how the new Ion Torrent Genexus System is addressing key challenges to next-generation sequencing (NGS) implementation, like hands-on time, time-to-result, user expertise, and af...
    Speaker: Jon Sherlock, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
    JUN 03, 2020 | 4:00 PM
    Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢ Technology
    Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢...
    The RNAscope in situ hybridization technology allows high sensitivity, specificity and spatial resolution providing pivotal single-cell gene expression information to gain better insights in...
    Speaker: Anushka Dikshit, PhD
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: Advanced Cell Diagnostics
    0
     
     
  • MAY 20, 2020 | 12:00 AM
    Single-cell Genomics Tools for better understanding and treatment of Human Disease
    Single-cell Genomics Tools for better understanding and treatment...
    The basic units of biological structure and function are cells, which exhibit wide variation in regard to both type and state. We assess such variation by simultaneously profiling the transc...
    Speaker: Anindita Basu, PhD
    Presented at: Laboratory Automation & Informatics Virtual Event Series 2020
    2
    MAY 19, 2020 | 1:45 PM
    Cancer Transcriptome Atlas with NGS Readout - The essential tool for spatial genomics in oncology
    Cancer Transcriptome Atlas with NGS Readout - The essential tool...
    While many technologies focus on either exploring the spatial context of a handful of targets, or expression patterns of hundreds or thousands of targets in bulk samples or dissociated singl...
    Speaker: Kit Fuhrman, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 19, 2020 | 1:45 PM
    Tumor Signaling 360 Panel: A 360° View of Altered Signaling Pathways in Cancer
    Tumor Signaling 360 Panel: A 360° View of Altered Signaling Pathways...
    Targeted therapies for cancer are increasingly being developed as an alternative for, and in addition to, immunotherapy. Altered tumor signaling can be exploited to single-out cancer cells f...
    Speaker: Erin Piazza, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    3
    MAY 19, 2020 | 1:15 PM
    Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢ Technology
    Spatial Mapping of Gene Expression in Tumors using the RNAscopeâ„¢...
    The RNAscope in situ hybridization technology allows high sensitivity, specificity and spatial resolution providing pivotal single-cell gene expression information to gain better insights in...
    Speaker: Anushka Dikshit, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    3
    MAY 19, 2020 | 11:45 AM
    Single-nucleus and Spatial Transcriptomics of Archival Pancreatic Ductal Adenocarcinoma after Neoadjuvant Treatment
    Single-nucleus and Spatial Transcriptomics of Archival Pancreatic...
    Pancreatic ductal adenocarcinoma (PDAC) remains a treatment-refractory disease and existing molecular subtypes do not inform clinical decisions. Previously-identified bulk transcriptomic sub...
    Speaker: William L. Hwang, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
     
     
  • MAY 19, 2020 | 11:15 AM
    Digital Spatial Mapping of the Immune Landscape of Triple Negative Breast Cancer Reveals Novel Features of Immune-tumor Cell Interaction
    Digital Spatial Mapping of the Immune Landscape of Triple Negative...
    Background: Growing evidence supports the critical role of preexisting immune response in triple negative breast cancer (TNBC). However, there are limitations with current evaluation approac...
    Speaker: E. Aubrey Thompson, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 14, 2020 | 2:40 PM
    Oncomine Precision Assay on Ion Torrent Genexus System for liquid biopsy sample
    Oncomine Precision Assay on Ion Torrent Genexus System for liquid...
    Molecular profiling is key in precision oncology research and whilst the tissue testing has become a routine, liquid biopsy might provide a non-invasive alternative when tissue biopsy is ina...
    Speaker: Siew-Kee (Amanda) Low, PhD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    8
    MAY 14, 2020 | 2:40 PM
    Oncomine Precision Assay on Ion Torrent Genexus System for liquid biopsy sample
    Oncomine Precision Assay on Ion Torrent Genexus System for liquid...
    The development of molecular targeted therapy is one of the breakthroughs in oncology field. Molecular profiling of the tumor becomes mandatory in the routine clinical practice to select the...
    Speaker: Siew-Kee (Amanda) Low, PhD
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    APR 24, 2020 | 9:00 AM
    Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs) with the CODEX® Platform
    Deep Immune Profiling of Peripheral Blood Mononuclear Cells (PBMCs)...
    DATE: April 24, 2020 TIME: 9:00am PT, 12:00pm ET Single-cell analysis of cell suspensions is increasingly important in studies of infectious diseases, cancer and autoimmune disorders, given...
    Speaker: Jon Mulholland, MS , Anum Khan, PhD , Oliver Braubach, Ph.D.
    Sponsored By: Akoya Biosciences
    6
    APR 23, 2020 | 9:00 AM
    Keynote Presentation: Individualized Health
    Keynote Presentation: Individualized Health
    Learning Objectives: 1. What is wrong with healthcare today 2. What kinds of omics and wearables data can be used to best predict disease risk and manage health...
    Speaker: Michael Snyder, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
     
     
  • APR 22, 2020 | 12:00 AM
    Precision Infectious Disease Diagnostics Using Next-Generation Sequencing and AI
    Precision Infectious Disease Diagnostics Using Next-Generation...
    As the spread of infectious diseases, current pandemic, and growing antimicrobial resistance (AMR) continues globally, next-generation sequencing (NGS) and specifically metagenomics became a...
    Speaker: Dorottya Nagy-Szakal, MD PhD
    Presented at: Genetics Week Virtual Event Series 2020
    2
    APR 21, 2020 | 1:30 PM
    Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
    Spatially Resolved Molecular Investigation of Triple Negative...
    Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
    Speaker: Dina Finan, PhD , Stephen Williams, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 21, 2020 | 12:00 PM
    SNVs to Large Structural Variation: Capturing nucleotide through inter-chromosomal variants through a powerful three-dimensional data type
    SNVs to Large Structural Variation: Capturing nucleotide through...
    Within the clinical arena, the oncology community has led the way in the early adoption of next generation sequencing. NGS is in widespread use in clinical cancer research and is now beginni...
    Speaker: Cory Padilla, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 21, 2020 | 10:30 AM
    Optimizing human karyomapping to phase single lgene defects with improved DNA amplification
    Optimizing human karyomapping to phase single lgene defects with...
    Karyomapping, a technique for preimplantation genetic diagnosis (PGD) of single gene disorders, involves using very few or single cells, and comes with challenges due to limited amounts of s...
    Speaker: Samuel Rulli, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    1
    APR 21, 2020 | 12:00 AM
    Single Cell Multi-omics: Solving the Jigsaw
    Single Cell Multi-omics: Solving the Jigsaw
    Since the introduction of single cell sequencing techniques to the genomics community, interest in its use has grown exponentially and the number of single cell publications has exploded. Th...
    Speaker: Ivan Lukić, MD, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
     
     
  • APR 21, 2020 | 12:00 AM
    Single cell gene expression: new insights through the lens of full length mRNA isoform resolution
    Single cell gene expression: new insights through the lens of...
    Single cell RNA sequencing (scRNA-seq) emerged to characterize gene expression differences between individual cells, allowing a higher resolution look at mRNA abundance than bulk RNA- seq. H...
    Speaker: Jason Underwood, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    MAR 17, 2020 | 8:00 AM
    Multiplexing on Mouse tissue using Cell Signaling Technology antibodies and OPAL IHC method
    Multiplexing on Mouse tissue using Cell Signaling Technology antibodies...
    DATE: March 17, 2020 TIME: 8:00am PT, 11:00am PT Cell Signaling Technology: The determination of target specificity in immunohistochemical analysis requires multiple validation steps. This w...
    Speaker: Bill Kennedy , Christopher Grange
    Sponsored By: Akoya Biosciences, Cell Signaling Technology
    9
    DEC 17, 2019 | 8:00 AM
    Single-Cell Phosphoprotein Analysis with CyTOF: From Training to Immuno-Oncology Clinical Research
    Single-Cell Phosphoprotein Analysis with CyTOF: From Training...
    DATE: December 17, 2019TIME: 8:00am PSTMass cytometry instruments simultaneously measure >50 cellular features, with a typical experiment including millions of cells. Dysregulated...
    Speaker: Jonathan Irish, PhD , Caroline E. Roe, BS
    Sponsored By: Standard BioTools
    7 2
    DEC 05, 2019 | 9:00 AM
    Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
    Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments
    DATE: December 5, 2019TIME: 9:00am PST, 12:00pm EST Characterization of the spatial distribution and abundance of proteins and mRNAs with morphological context within tissues e...
    Speaker: Mathias Holpert, PhD , Traci DeGeer, BS, HT (ASCP) HTL, QIHC
    Sponsored By: Leica Biosystems, NanoString Technologies
    8
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