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    Single Cell Sequencing

    Single cell sequencing is a next-generation sequencing (NGS) method that examines the genomes or transcriptomes of individual cells, giving a high-resolution view of cell-to-cell variation. Single-cell RNA sequencing (scRNA-seq) technologies allow the dissection of gene expression at single-cell resolution, which greatly revolutionizes transcriptomic studies.

    Webinars

    • APR 06, 2016 | 6:00 AM
      EFIRM Liquid Biopsy
      EFIRM Liquid Biopsy
      The advent of personalized medicine employing molecular targeted therapies has markedly changed the treatment of cancer in the past 10 years. Although tumor tissue biopsy-based genotyping is...
      Speaker: David Wong DMD, DMSc
      Presented at: Molecular Diagnostics Virtual Event Series 2016
      5 1
      MAR 29, 2016 | 8:00 AM
      WEBINAR: Applications of Targeted Gene Panels in Inherited Disease Research
      WEBINAR: Applications of Targeted Gene Panels in Inherited Disease...
      Recent advances in next-generation sequencing (NGS) have helped to accelerate the pace of discovery in the field of genetic disease research and testing. The ability to analyze multiple genes...
      Speaker: Brian Meyer, PhD , Robert Sebra, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent, Thermo Fisher Scientific - Ion Torrent
      11 3
      FEB 24, 2016 | 3:00 PM
      Bringing precision medicine in oncology to South Africa
      Bringing precision medicine in oncology to South Africa
      The greatest health epidemic of our time is cancer. Deaths from cancer worldwide outnumber the combined deaths from HIV/AIDS, tuberculosis and malaria by a wide margin. There are at least 100...
      Speaker: Musa Mhlanga, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 24, 2016 | 2:00 PM
      Why we should clinically classify genotypes, not variants
      Why we should clinically classify genotypes, not variants
      A century and a half after we first probed heritability, we risk forgetting one of Mendel's own basic findings, in rushing to broaden clinical genomics to lifelong care for all. Embracing...
      Speaker: Nathaniel Pearson, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 24, 2016 | 8:00 AM
      Keynote Presentation - Integrating the digital universe of data with consumer-driven mobile apps and large-scale panomics data to better understand, treat, and prevent disease
      Keynote Presentation - Integrating the digital universe of data...
      One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...
      Speaker: Eric Schadt, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 24, 2016 | 7:00 AM
      Towards precision medicine
      Towards precision medicine
      Understanding disease at a deeper level so that it can be targeted more precisely is the essence of precision medicine. Rapid technological advance, particularly in genomics and sensor-based...
      Speaker: Euan Ashley, MRCP, DPhil
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 04, 2016 | 3:00 PM
      Problems when breeding laboratory mice: why are pups dying?
      Problems when breeding laboratory mice: why are pups dying?
      A crucial part of providing animals for research is successful breeding. Still, in many mouse facilities breeding efficiency is complicated by problems with reproduction, such as pre-weaning...
      Speaker: Elin Weber, PhD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      5
      SEP 30, 2015 | 1:30 PM
      SuperSelective Primers for the Multiplex Quantitation of Rare Mutant Sequences Associated with Cancer
      SuperSelective Primers for the Multiplex Quantitation of Rare...
      A major goal of molecular diagnostics is to find a sensitive and specific means for detecting and quantifying DNA fragments from rare cancer cells (by virtue of an identifying somatic mutatio...
      Speaker: Fred Kramer, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 12:00 PM
      Modeling and dissecting hepatocellular carcinoma dissemination
      Modeling and dissecting hepatocellular carcinoma dissemination
      Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
      Speaker: Brian Lewis, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 30, 2015 | 6:00 AM
      Comparative genome and transcriptome analysis of small cell numbers
      Comparative genome and transcriptome analysis of small cell numbers
      The genome determines changes of the transcription profile upon environmental changes and finally determines how a cell reacts. A comparative genome and transcriptome analysis of the same sam...
      Speaker: Christian Korfhage, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      MAY 13, 2015 | 10:30 AM
      Statistical methods for bulk and single-cell RNA-seq experiments
      Statistical methods for bulk and single-cell RNA-seq experiments
      I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
      Speaker: Christina Kendziorski, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      4 1
      AUG 21, 2014 | 9:45 AM
      Shotgun sequencing enables non-invasive monitoring of infection and rejection in transplantation
      Shotgun sequencing enables non-invasive monitoring of infection...
      Accurate and timely diagnosis of rejection and infection is essential for long-term survival of solid-organ transplant recipients. We evaluated the performance a novel test to monitor rejecti...
      Speaker: Iwijn De Vlaminck, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      64
      AUG 21, 2014 | 9:30 AM
      Studying the Transcriptome with Next-Generation Sequencing
      Studying the Transcriptome with Next-Generation Sequencing
      Next-Generation Sequencing is enabling scientists to study the transcriptome in ways never before possible. During this session with Illumina Distinguished Scientist, Dr. Gary Schroth, you w...
      Speaker: Gary Schroth,PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      68
      AUG 20, 2014 | 11:30 AM
      More Comprehensive Views of Human Genetic Variation
      More Comprehensive Views of Human Genetic Variation
      High-throughput short-read DNA sequencing has revolutionized our ability to measure genetic variation in the form of single-nucleotide polymorphisms (SNPs) in human genomes. However, ~75% of...
      Speaker: Jonas Korlach, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      8
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Investigating tissue specificity of cancer-causing germline mutations
      Investigating tissue specificity of cancer-causing germline mutations
      The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
      Speaker: Jessica C. Mar, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      68
      OCT 16, 2013 | 11:00 AM
      SuperSelective PCR Primers for the Detection of Rare Mutant Cancer Cells in Clinical Samples Containing Abundant Normal Cells
      SuperSelective PCR Primers for the Detection of Rare Mutant Cancer...
      "SuperSelective" primers, by virtue of their unique design, enable only a few molecules of a mutant sequence to generate amplicons in conventional, real-time PCR assays without interference...
      Speaker: Fred Kramer, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      90
      AUG 21, 2013 | 3:00 PM
      C.E. CREDITS
      Investigating tissue specificity of cancer-causing germline mutations
      Investigating tissue specificity of cancer-causing germline mutations
      The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
      Speaker: Jessica C. Mar, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      70
      AUG 21, 2013 | 2:00 PM
      C.E. CREDITS
      Comprehensive Chromosome Screening in the Human Embryo
      Comprehensive Chromosome Screening in the Human Embryo
      The human species is particularly prone to chromosome segregation errors during maternal meiosis in the egg and during post zygotic mitosis in the preimplantation embryo. In fact, aneuploidy...
      Speaker: Nathan R Treff, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      33
    APR 06, 2016 | 6:00 AM
    EFIRM Liquid Biopsy
    EFIRM Liquid Biopsy
    The advent of personalized medicine employing molecular targeted therapies has markedly changed the treatment of cancer in the past 10 years. Although tumor tissue biopsy-based genotyping is...
    Speaker: David Wong DMD, DMSc
    Presented at: Molecular Diagnostics Virtual Event Series 2016
    5 1
    MAR 29, 2016 | 8:00 AM
    WEBINAR: Applications of Targeted Gene Panels in Inherited Disease Research
    WEBINAR: Applications of Targeted Gene Panels in Inherited Disease...
    Recent advances in next-generation sequencing (NGS) have helped to accelerate the pace of discovery in the field of genetic disease research and testing. The ability to analyze multiple genes...
    Speaker: Brian Meyer, PhD , Robert Sebra, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent, Thermo Fisher Scientific - Ion Torrent
    11 3
    FEB 24, 2016 | 3:00 PM
    Bringing precision medicine in oncology to South Africa
    Bringing precision medicine in oncology to South Africa
    The greatest health epidemic of our time is cancer. Deaths from cancer worldwide outnumber the combined deaths from HIV/AIDS, tuberculosis and malaria by a wide margin. There are at least 100...
    Speaker: Musa Mhlanga, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 24, 2016 | 2:00 PM
    Why we should clinically classify genotypes, not variants
    Why we should clinically classify genotypes, not variants
    A century and a half after we first probed heritability, we risk forgetting one of Mendel's own basic findings, in rushing to broaden clinical genomics to lifelong care for all. Embracing...
    Speaker: Nathaniel Pearson, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 24, 2016 | 8:00 AM
    Keynote Presentation - Integrating the digital universe of data with consumer-driven mobile apps and large-scale panomics data to better understand, treat, and prevent disease
    Keynote Presentation - Integrating the digital universe of data...
    One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...
    Speaker: Eric Schadt, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
     
     
  • FEB 24, 2016 | 7:00 AM
    Towards precision medicine
    Towards precision medicine
    Understanding disease at a deeper level so that it can be targeted more precisely is the essence of precision medicine. Rapid technological advance, particularly in genomics and sensor-based...
    Speaker: Euan Ashley, MRCP, DPhil
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 04, 2016 | 3:00 PM
    Problems when breeding laboratory mice: why are pups dying?
    Problems when breeding laboratory mice: why are pups dying?
    A crucial part of providing animals for research is successful breeding. Still, in many mouse facilities breeding efficiency is complicated by problems with reproduction, such as pre-weaning...
    Speaker: Elin Weber, PhD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    5
    SEP 30, 2015 | 1:30 PM
    SuperSelective Primers for the Multiplex Quantitation of Rare Mutant Sequences Associated with Cancer
    SuperSelective Primers for the Multiplex Quantitation of Rare...
    A major goal of molecular diagnostics is to find a sensitive and specific means for detecting and quantifying DNA fragments from rare cancer cells (by virtue of an identifying somatic mutatio...
    Speaker: Fred Kramer, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 30, 2015 | 12:00 PM
    Modeling and dissecting hepatocellular carcinoma dissemination
    Modeling and dissecting hepatocellular carcinoma dissemination
    Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
    Speaker: Brian Lewis, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 30, 2015 | 6:00 AM
    Comparative genome and transcriptome analysis of small cell numbers
    Comparative genome and transcriptome analysis of small cell numbers
    The genome determines changes of the transcription profile upon environmental changes and finally determines how a cell reacts. A comparative genome and transcriptome analysis of the same sam...
    Speaker: Christian Korfhage, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
     
     
  • MAY 13, 2015 | 10:30 AM
    Statistical methods for bulk and single-cell RNA-seq experiments
    Statistical methods for bulk and single-cell RNA-seq experiments
    I will discuss recent statistical methods for identifying differentially expressed genes in static and time course bulk RNA-seq experiments. I will also provide an overview of the opportunit...
    Speaker: Christina Kendziorski, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    4 1
    AUG 21, 2014 | 9:45 AM
    Shotgun sequencing enables non-invasive monitoring of infection and rejection in transplantation
    Shotgun sequencing enables non-invasive monitoring of infection...
    Accurate and timely diagnosis of rejection and infection is essential for long-term survival of solid-organ transplant recipients. We evaluated the performance a novel test to monitor rejecti...
    Speaker: Iwijn De Vlaminck, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    64
    AUG 21, 2014 | 9:30 AM
    Studying the Transcriptome with Next-Generation Sequencing
    Studying the Transcriptome with Next-Generation Sequencing
    Next-Generation Sequencing is enabling scientists to study the transcriptome in ways never before possible. During this session with Illumina Distinguished Scientist, Dr. Gary Schroth, you w...
    Speaker: Gary Schroth,PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    68
    AUG 20, 2014 | 11:30 AM
    More Comprehensive Views of Human Genetic Variation
    More Comprehensive Views of Human Genetic Variation
    High-throughput short-read DNA sequencing has revolutionized our ability to measure genetic variation in the form of single-nucleotide polymorphisms (SNPs) in human genomes. However, ~75% of...
    Speaker: Jonas Korlach, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    8
    OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Investigating tissue specificity of cancer-causing germline mutations
    Investigating tissue specificity of cancer-causing germline mutations
    The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
    Speaker: Jessica C. Mar, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    68
     
     
  • OCT 16, 2013 | 11:00 AM
    SuperSelective PCR Primers for the Detection of Rare Mutant Cancer Cells in Clinical Samples Containing Abundant Normal Cells
    SuperSelective PCR Primers for the Detection of Rare Mutant Cancer...
    "SuperSelective" primers, by virtue of their unique design, enable only a few molecules of a mutant sequence to generate amplicons in conventional, real-time PCR assays without interference...
    Speaker: Fred Kramer, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    90
    AUG 21, 2013 | 3:00 PM
    C.E. CREDITS
    Investigating tissue specificity of cancer-causing germline mutations
    Investigating tissue specificity of cancer-causing germline mutations
    The remarkable diversity we see between different cell types in the human body is governed by the specificity attained through transcriptional and epigenetic regulatory programs. Cancer is a...
    Speaker: Jessica C. Mar, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    70
    AUG 21, 2013 | 2:00 PM
    C.E. CREDITS
    Comprehensive Chromosome Screening in the Human Embryo
    Comprehensive Chromosome Screening in the Human Embryo
    The human species is particularly prone to chromosome segregation errors during maternal meiosis in the egg and during post zygotic mitosis in the preimplantation embryo. In fact, aneuploidy...
    Speaker: Nathan R Treff, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    33
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