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    Target Capture

    Target capture is a high throughput method to sequence a specific region of genomic data. Target capture technology is an efficient and cost-effective method that can be used to detect variants in the gene sequence to identify disease.

    Webinars

    • JAN 31, 2019 | 10:30 AM
      Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries to Improve Process Efficiencies
      Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries...
      Multi-mode chromatography has come to prominence in recent years due to the general utility of multi-mode ligands for product capture and polishing. In particular, their application in flow-t...
      Speaker: Buzz Lobbezoo
      Presented at: BioProcessing Virtual Event Series 2019
      Sponsored By: Astrea Bioseparations
      1
      NOV 15, 2018 | 10:00 AM
      Multiplex fluorescence immunohistochemistry using the Ultivue InSituPlex platform on the Leica Biosystems BOND RX
      Multiplex fluorescence immunohistochemistry using the Ultivue...
      DATE:  November 15, 2018TIME:  10:00am PT, 1:00pm ET Multiplex fluorescence immunohistochemistry offers a window into the biology of human disease, enabling the ana...
      Speaker: Traci DeGeer, BS, HT (ASCP) HTL, QIHC , Alexander Klimowicz
      Sponsored By: Leica Biosystems
      6 1
      OCT 23, 2018 | 9:00 AM
      Chicago® and Dovetail™ Hi-C yield chromosome length scaffolds of the Ixodes scapularis genome
      Chicago® and Dovetail™ Hi-C yield chromosome length scaffolds...
      DATE: October 23, 2018TIME: 9:00AM PDTIxodes scapularis is the principal vector of the Lyme disease spirochete, Borrelia burgdorferi. I. scapularis genome was the first and only...
      Speaker: Monika Gulia-Nuss
      Sponsored By: Dovetail Genomics
      5
      OCT 11, 2018 | 8:00 AM
      Tissue Biomarker Analysis: A Practical Approach for Translational Research
      Tissue Biomarker Analysis: A Practical Approach for Translational...
      DATE: October 11, 2018TIME: 8:00AM PDTSimultaneous quantitation of 6 or more biomarkers in intact tissue specimens holds the key to many questions concerning the biological basis o...
      Speaker: Grady Carlson, PhD , Linden Wyatt, PhD
      Sponsored By: Revvity
      6
      AUG 30, 2018 | 8:00 AM
      Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
      Early disease detection performing NMR - Understanding how a better...
      DATE: August 30, 2018TIME: 11:00am EDT, 5:00pm CEST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturally, as well...
      Speaker: Elaine Holmes , Claudio Luchinat
      Sponsored By: Bruker Microbiology & Diagnostics
      6 2
      AUG 30, 2018 | 1:00 AM
      Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
      Early disease detection performing NMR - Understanding how a better...
      DATE: August 30, 2018TIME:  10:00am CEST, 4:00pm CST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturall...
      Speaker: Elaine Holmes , Claudio Luchinat
      Sponsored By: Bruker Microbiology & Diagnostics
      5 2
      JUN 26, 2018 | 9:00 AM
      Automated In Vivo Efficacy Assessment in Preclinical Lung Disease Models
      Automated In Vivo Efficacy Assessment in Preclinical Lung Disease...
      Treatments for respiratory diseases represent an enormous, unmet medical need with limited therapies currently approved for use. Despite many compounds demonstrating beneficial effects in ani...
      Speaker: Laura Schaevitz, PhD
      Sponsored By: Vium
      6
      JUN 21, 2018 | 12:00 PM
      Whole Genome Sequencing As A Valuable Clinical Tool For the Management of Cancer Patients
      Whole Genome Sequencing As A Valuable Clinical Tool For the Management...
      Advances in DNA sequencing, based upon massively parallel sequencing, has resulted in dramatic advances in DNA sequence output in the past few years. It is now possible to generate terrabases...
      Speaker: David Smith, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 21, 2018 | 10:30 AM
      Setting Up Next-Generation Sequencing for the Needs of Routine Molecular Diagnostics With a Focus on the Suitability of the GeneReader NGS System for Lung Cancer Patients
      Setting Up Next-Generation Sequencing for the Needs of Routine...
      The introduction of targeted therapies into the clinical management of lung adenocarcinoma has had a massive impact on patient care. Multiple driver mutations are now druggable and treatments...
      Speaker: Paul Hofman, MD, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      JUN 20, 2018 | 12:00 PM
      Precision Medicine: The Way Forward!
      Precision Medicine: The Way Forward!
      Recent advancements in the precision medicine field have presented a great promise to provide innovative solutions to pharmaceutical and healthcare industry to help transform medicine. By fin...
      Speaker: Prasun Mishra, MsC, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 20, 2018 | 10:30 AM
      Panel Discussion: VA Genomics - The Clinic and Research
      Panel Discussion: VA Genomics - The Clinic and Research
      With nearly 9 million covered lives serviced through over 150 medical centers, the VA is one of the largest, unified Healthcare System within the United States. Embedded within this system is...
      Speaker: Laurence Meyer, MD, PhD , Ronald Przygodzki, MD
      Presented at: Precision Medicine Virtual Event Series 2018
      2
      MAR 29, 2018 | 7:30 AM
      Keynote Presentation: Better Science - Better Quality of Life
      Keynote Presentation: Better Science - Better Quality of Life
      For 100 years the cannabis plant has been demonized, made illegal, and kept from researchers. Recently, states have begun to take the situation into their own hands, enabling patients to...
      Speaker: Russ Cersosimo Jr.
      Presented at: Cannabis Sciences Virtual Event Series 2018
      1
      MAR 27, 2018 | 9:00 AM
      Proteomics profiling of post-translational modifications in early drug discovery
      Proteomics profiling of post-translational modifications in early...
      DATE: March 27, 2018TIME: 09:00am PST, 12:00pm EST...
      Speaker: Matthew Stokes, PhD , Lilian Phu , Don Kirkpatrick, PhD
      Sponsored By: Cell Signaling Technology
      8 3
      NOV 09, 2017 | 9:00 AM
      Accelerating Immuno-Oncology Research with the PanCancer IO 360â„¢ Gene Expression Panel, Advanced Data Analysis Service, and Signature Development
      Accelerating Immuno-Oncology Research with the PanCancer IO 360â„¢...
      Transcriptional profiling of the tumor microenvironment can lead to insights about the interaction between the tumor and immune system. This facilitates investigation of immune evasion mechan...
      Speaker: Sarah Warren, PhD , Patrick Danaher, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      Sponsored By: NanoString Technologies
      1
      OCT 12, 2017 | 9:00 AM
      Profiling the cell surface of cancer cell lines for biomarker/drug target discovery using MS-based proteomics
      Profiling the cell surface of cancer cell lines for biomarker/drug...
      In order to expand the treatment options of cancers driven by oncogenic RAS, new cell surface targets need to be identified and characterized. Here, we describe mass spectrometry based phenot...
      Speaker: Josip Blonder, MD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      3
      OCT 11, 2017 | 12:00 PM
      Examining Cancer with the minION: Methylation and Structural Variation
      Examining Cancer with the minION: Methylation and Structural Variation
      Nanopore sequencing has enormous potential for application to cancer, but specifically offers advantages into two main arenas, epigenetics and structural variation. Methylation is well-known...
      Speaker: Winston Timp, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      Sponsored By: Oxford Nanopore Technologies
      1
      FEB 23, 2017 | 12:00 PM
      Novel Precision medicines that exploit Proximity
      Novel Precision medicines that exploit Proximity
      Cell growth and regulation involve vast networks of interacting DNAs, RNAs, proteins, lipids and sugars. Through a fundamental strategy of life, these interactions push multiple cellular proc...
      Speaker: James Prudent, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      3
      FEB 23, 2017 | 6:00 AM
      Validation and Commercialization of Liquid Biopsy in a CLIA Lab
      Validation and Commercialization of Liquid Biopsy in a CLIA Lab
      Liquid Biopsies are gaining acceptance in the Oncology community as a surrogate or complement to the gold standard of tissue biopsy.  A liquid biopsy provides biomarker information that...
      Speaker: Michael Nall
      Presented at: Precision Medicine Virtual Event Series 2017
      2
      FEB 22, 2017 | 12:00 PM
      From Bits to Bedside: Translating Big Data into Precision Medicine and Digital Health
      From Bits to Bedside: Translating Big Data into Precision Medicine...
      In this talk, I will use examples from my research using big data analytics to define ideals of precision medicine and digital health across a variety of diseases. Specifically, I will i...
      Speaker: Dexter Hadley, MD, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      3
      FEB 22, 2017 | 10:30 AM
      Beyond the hype: the evidence behind the role of genetics in drug response
      Beyond the hype: the evidence behind the role of genetics in drug...
      Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease.  While there is a scientific basis...
      Speaker: Matt Nelson, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      5
      FEB 09, 2017 | 9:00 AM
      Improved decision making in the drug discovery process using an innovative approach to modelling chronic liver disease
      Improved decision making in the drug discovery process using an...
      DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETTraditional models of liver fibrosis in rodents involve many weeks of induction, with frequent injections of a pro-fibrotic agent. The m...
      Speaker: Steve England, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      2
      NOV 08, 2016 | 6:00 AM
      New Approaches to Antibody Validation Using Immunoprecipitation and Mass Spectrometry
      New Approaches to Antibody Validation Using Immunoprecipitation...
      Antibodies are used in a broad range of research and diagnostic applications for the enrichment, detection, and quantitation of proteins and their modifications.  Hundreds of thousands o...
      Speaker: John Rogers, PhD
      Presented at: Protein and Cell Analysis Education Series
      Sponsored By: Thermo Fisher Scientific
      9 2
      OCT 06, 2016 | 6:00 AM
      Detection and analysis of circulating tumor cells - challenges and solutions
      Detection and analysis of circulating tumor cells - challenges...
      Circulating Tumor Cells (CTCs) have been extensively explored as circulating biomarkers in various cancers. Due to their rarity, heterogeneity and stem cell-like properties, detecting and pro...
      Speaker: Siegfried Hauch
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      3
      MAY 11, 2016 | 6:00 AM
      Natural Human Gene Knockouts and the Discovery of New Drug Targets
      Natural Human Gene Knockouts and the Discovery of New Drug Targets
      It has been estimated that every human being carries ~20 rare “natural human gene knockouts”-DNA variants in protein-coding regions of the genome that partially or completely inac...
      Speaker: Frederick Dewey, MD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      4
    JAN 31, 2019 | 10:30 AM
    Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries to Improve Process Efficiencies
    Flow-Through Polishing and The Use of Multi-Mode Ligand Libraries...
    Multi-mode chromatography has come to prominence in recent years due to the general utility of multi-mode ligands for product capture and polishing. In particular, their application in flow-t...
    Speaker: Buzz Lobbezoo
    Presented at: BioProcessing Virtual Event Series 2019
    Sponsored By: Astrea Bioseparations
    1
    NOV 15, 2018 | 10:00 AM
    Multiplex fluorescence immunohistochemistry using the Ultivue InSituPlex platform on the Leica Biosystems BOND RX
    Multiplex fluorescence immunohistochemistry using the Ultivue...
    DATE:  November 15, 2018TIME:  10:00am PT, 1:00pm ET Multiplex fluorescence immunohistochemistry offers a window into the biology of human disease, enabling the ana...
    Speaker: Traci DeGeer, BS, HT (ASCP) HTL, QIHC , Alexander Klimowicz
    Sponsored By: Leica Biosystems
    6 1
    OCT 23, 2018 | 9:00 AM
    Chicago® and Dovetail™ Hi-C yield chromosome length scaffolds of the Ixodes scapularis genome
    Chicago® and Dovetail™ Hi-C yield chromosome length scaffolds...
    DATE: October 23, 2018TIME: 9:00AM PDTIxodes scapularis is the principal vector of the Lyme disease spirochete, Borrelia burgdorferi. I. scapularis genome was the first and only...
    Speaker: Monika Gulia-Nuss
    Sponsored By: Dovetail Genomics
    5
    OCT 11, 2018 | 8:00 AM
    Tissue Biomarker Analysis: A Practical Approach for Translational Research
    Tissue Biomarker Analysis: A Practical Approach for Translational...
    DATE: October 11, 2018TIME: 8:00AM PDTSimultaneous quantitation of 6 or more biomarkers in intact tissue specimens holds the key to many questions concerning the biological basis o...
    Speaker: Grady Carlson, PhD , Linden Wyatt, PhD
    Sponsored By: Revvity
    6
    AUG 30, 2018 | 8:00 AM
    Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
    Early disease detection performing NMR - Understanding how a better...
    DATE: August 30, 2018TIME: 11:00am EDT, 5:00pm CEST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturally, as well...
    Speaker: Elaine Holmes , Claudio Luchinat
    Sponsored By: Bruker Microbiology & Diagnostics
    6 2
     
     
  • AUG 30, 2018 | 1:00 AM
    Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help  (For research use only)
    Early disease detection performing NMR - Understanding how a better...
    DATE: August 30, 2018TIME:  10:00am CEST, 4:00pm CST The need to quantify urine is valuable because it provides information on chemicals that the body makes naturall...
    Speaker: Elaine Holmes , Claudio Luchinat
    Sponsored By: Bruker Microbiology & Diagnostics
    5 2
    JUN 26, 2018 | 9:00 AM
    Automated In Vivo Efficacy Assessment in Preclinical Lung Disease Models
    Automated In Vivo Efficacy Assessment in Preclinical Lung Disease...
    Treatments for respiratory diseases represent an enormous, unmet medical need with limited therapies currently approved for use. Despite many compounds demonstrating beneficial effects in ani...
    Speaker: Laura Schaevitz, PhD
    Sponsored By: Vium
    6
    JUN 21, 2018 | 12:00 PM
    Whole Genome Sequencing As A Valuable Clinical Tool For the Management of Cancer Patients
    Whole Genome Sequencing As A Valuable Clinical Tool For the Management...
    Advances in DNA sequencing, based upon massively parallel sequencing, has resulted in dramatic advances in DNA sequence output in the past few years. It is now possible to generate terrabases...
    Speaker: David Smith, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 21, 2018 | 10:30 AM
    Setting Up Next-Generation Sequencing for the Needs of Routine Molecular Diagnostics With a Focus on the Suitability of the GeneReader NGS System for Lung Cancer Patients
    Setting Up Next-Generation Sequencing for the Needs of Routine...
    The introduction of targeted therapies into the clinical management of lung adenocarcinoma has had a massive impact on patient care. Multiple driver mutations are now druggable and treatments...
    Speaker: Paul Hofman, MD, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    JUN 20, 2018 | 12:00 PM
    Precision Medicine: The Way Forward!
    Precision Medicine: The Way Forward!
    Recent advancements in the precision medicine field have presented a great promise to provide innovative solutions to pharmaceutical and healthcare industry to help transform medicine. By fin...
    Speaker: Prasun Mishra, MsC, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
     
     
  • JUN 20, 2018 | 10:30 AM
    Panel Discussion: VA Genomics - The Clinic and Research
    Panel Discussion: VA Genomics - The Clinic and Research
    With nearly 9 million covered lives serviced through over 150 medical centers, the VA is one of the largest, unified Healthcare System within the United States. Embedded within this system is...
    Speaker: Laurence Meyer, MD, PhD , Ronald Przygodzki, MD
    Presented at: Precision Medicine Virtual Event Series 2018
    2
    MAR 29, 2018 | 7:30 AM
    Keynote Presentation: Better Science - Better Quality of Life
    Keynote Presentation: Better Science - Better Quality of Life
    For 100 years the cannabis plant has been demonized, made illegal, and kept from researchers. Recently, states have begun to take the situation into their own hands, enabling patients to...
    Speaker: Russ Cersosimo Jr.
    Presented at: Cannabis Sciences Virtual Event Series 2018
    1
    MAR 27, 2018 | 9:00 AM
    Proteomics profiling of post-translational modifications in early drug discovery
    Proteomics profiling of post-translational modifications in early...
    DATE: March 27, 2018TIME: 09:00am PST, 12:00pm EST...
    Speaker: Matthew Stokes, PhD , Lilian Phu , Don Kirkpatrick, PhD
    Sponsored By: Cell Signaling Technology
    8 3
    NOV 09, 2017 | 9:00 AM
    Accelerating Immuno-Oncology Research with the PanCancer IO 360â„¢ Gene Expression Panel, Advanced Data Analysis Service, and Signature Development
    Accelerating Immuno-Oncology Research with the PanCancer IO 360â„¢...
    Transcriptional profiling of the tumor microenvironment can lead to insights about the interaction between the tumor and immune system. This facilitates investigation of immune evasion mechan...
    Speaker: Sarah Warren, PhD , Patrick Danaher, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    Sponsored By: NanoString Technologies
    1
    OCT 12, 2017 | 9:00 AM
    Profiling the cell surface of cancer cell lines for biomarker/drug target discovery using MS-based proteomics
    Profiling the cell surface of cancer cell lines for biomarker/drug...
    In order to expand the treatment options of cancers driven by oncogenic RAS, new cell surface targets need to be identified and characterized. Here, we describe mass spectrometry based phenot...
    Speaker: Josip Blonder, MD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    3
     
     
  • OCT 11, 2017 | 12:00 PM
    Examining Cancer with the minION: Methylation and Structural Variation
    Examining Cancer with the minION: Methylation and Structural Variation
    Nanopore sequencing has enormous potential for application to cancer, but specifically offers advantages into two main arenas, epigenetics and structural variation. Methylation is well-known...
    Speaker: Winston Timp, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    Sponsored By: Oxford Nanopore Technologies
    1
    FEB 23, 2017 | 12:00 PM
    Novel Precision medicines that exploit Proximity
    Novel Precision medicines that exploit Proximity
    Cell growth and regulation involve vast networks of interacting DNAs, RNAs, proteins, lipids and sugars. Through a fundamental strategy of life, these interactions push multiple cellular proc...
    Speaker: James Prudent, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    3
    FEB 23, 2017 | 6:00 AM
    Validation and Commercialization of Liquid Biopsy in a CLIA Lab
    Validation and Commercialization of Liquid Biopsy in a CLIA Lab
    Liquid Biopsies are gaining acceptance in the Oncology community as a surrogate or complement to the gold standard of tissue biopsy.  A liquid biopsy provides biomarker information that...
    Speaker: Michael Nall
    Presented at: Precision Medicine Virtual Event Series 2017
    2
    FEB 22, 2017 | 12:00 PM
    From Bits to Bedside: Translating Big Data into Precision Medicine and Digital Health
    From Bits to Bedside: Translating Big Data into Precision Medicine...
    In this talk, I will use examples from my research using big data analytics to define ideals of precision medicine and digital health across a variety of diseases. Specifically, I will i...
    Speaker: Dexter Hadley, MD, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    3
    FEB 22, 2017 | 10:30 AM
    Beyond the hype: the evidence behind the role of genetics in drug response
    Beyond the hype: the evidence behind the role of genetics in drug...
    Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease.  While there is a scientific basis...
    Speaker: Matt Nelson, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    5
     
     
  • FEB 09, 2017 | 9:00 AM
    Improved decision making in the drug discovery process using an innovative approach to modelling chronic liver disease
    Improved decision making in the drug discovery process using an...
    DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETTraditional models of liver fibrosis in rodents involve many weeks of induction, with frequent injections of a pro-fibrotic agent. The m...
    Speaker: Steve England, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    2
    NOV 08, 2016 | 6:00 AM
    New Approaches to Antibody Validation Using Immunoprecipitation and Mass Spectrometry
    New Approaches to Antibody Validation Using Immunoprecipitation...
    Antibodies are used in a broad range of research and diagnostic applications for the enrichment, detection, and quantitation of proteins and their modifications.  Hundreds of thousands o...
    Speaker: John Rogers, PhD
    Presented at: Protein and Cell Analysis Education Series
    Sponsored By: Thermo Fisher Scientific
    9 2
    OCT 06, 2016 | 6:00 AM
    Detection and analysis of circulating tumor cells - challenges and solutions
    Detection and analysis of circulating tumor cells - challenges...
    Circulating Tumor Cells (CTCs) have been extensively explored as circulating biomarkers in various cancers. Due to their rarity, heterogeneity and stem cell-like properties, detecting and pro...
    Speaker: Siegfried Hauch
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    3
    MAY 11, 2016 | 6:00 AM
    Natural Human Gene Knockouts and the Discovery of New Drug Targets
    Natural Human Gene Knockouts and the Discovery of New Drug Targets
    It has been estimated that every human being carries ~20 rare “natural human gene knockouts”-DNA variants in protein-coding regions of the genome that partially or completely inac...
    Speaker: Frederick Dewey, MD
    Presented at: Genetics and Genomics Virtual Event Series 2016
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