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    Target Identification

    Target Identification: is the process of identifying the direct molecular target - for example protein or nucleic acid - of a small molecule. In clinical pharmacology, target identification is aimed at finding the efficacy target of a drug/pharmaceutical or other xenobiotic. The techniques used may be based on principles of biochemistry, biophysics, genetics, chemical biology or other disciplines.

    Webinars

    • FEB 03, 2021 | 12:30 PM
      Optimizing High-Content Imaging of 3D Models for Drug Discovery
      Optimizing High-Content Imaging of 3D Models for Drug Discovery
      In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
      Speaker: Arvonn Tully , Judi Wardwell-Swanson
      Presented at: 7th Annual Conference: SBI2 High Content
      Sponsored By: SBI2, InSphero , Yokogawa
      11 10
      DEC 16, 2020 | 7:00 AM
      The Impact of MBT Sepsityper®: The Lahey Experience
      The Impact of MBT Sepsityper®: The Lahey Experience
      Date: December 16, 2020 Time: 7:00am (PST), 10:00am (EST) During this webinar we will discuss the implementation and impact of the MALDI Biotyper® and the MBT Sepsityper® in the clinical mi...
      Speaker: Felicia Maida, GCertHSA, BS, MT(ASCP)
      Sponsored By: Bruker Microbiology & Infection Diagnostics
      6
      DEC 03, 2020 | 4:30 PM
      An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
      An Iterative Approach to Structure-based in silico to in vivo...
      This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
      Speaker: Garth Ehrlich, PhD, FAAAS
      Presented at: Coronavirus Series
      5
      NOV 20, 2020 | 8:00 AM
      Efficiency to Confidence with High Resolution Accurate Mass Spectrometers: Analyzing IGF-1
      Efficiency to Confidence with High Resolution Accurate Mass Spectrometers:...
      DATE: November 20, 2020 TIME: 8am PDT, 11am EDT Insulin-like growth factor-1 (IGF-1) measurement by high-resolution accurate mass-mass spectrometry (HRAM) is replacing IGF-1 immunoassays and...
      Speaker: Tony Maus
      Sponsored By: Thermo Fisher Scientific
      7 1
      NOV 12, 2020 | 1:30 PM
      Covid-19 Testing and the role of Antigen assays today and moving forward
      Covid-19 Testing and the role of Antigen assays today and moving...
      Today's presentation will cover the following topics from the perspective of a NYC based Laboratory: What have we learned year to date about CoV-2 and specifically how diagnostic testing...
      Speaker: Vincent Streva, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: Diasorin
      1
      OCT 29, 2020 | 8:00 AM
      Cell types to targets: Single cell RNA-sequencing for drug discovery
      Cell types to targets: Single cell RNA-sequencing for drug discovery
      Date: October 29, 2020 Time: 8:00am (PDT), 11:00am (EDT) What cell types cause and perpetuate disease? For many diseases, scientists only have guesses to this critical question. Single cell...
      Speaker: Sarah Middleton, PhD
      Sponsored By: 10x Genomics
      10 2
      OCT 29, 2020 | 6:00 AM
      Single-cell sequencing to investigate epigenetic mechanisms in inflammatory lymphocytes
      Single-cell sequencing to investigate epigenetic mechanisms in...
      Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
      Speaker: Thomas Ayers, Ph.D. , Pawel Zajac, Ph.D. , Dr. Adam Cribbs
      Sponsored By: Illumina, Dolomite Bio
      15
      OCT 08, 2020 | 7:30 AM
      Keynote Presentation: RNA Splicing and Ancestry-related Molecular Targets in Precision Oncology and Cancer Disparities
      Keynote Presentation: RNA Splicing and Ancestry-related Molecular...
      Individuals of under-represented minority ancestry are at disproportional risk for higher incidence and mortality rates for particular cancers. The unequal burden of cancer in certain racial...
      Speaker: Steven R. Patierno, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      4
      OCT 08, 2020 | 12:00 AM
      Hereditary Cancer Genetics
      Hereditary Cancer Genetics
      Learning Objectives: 1. To provide an overview of relevant hereditary cancer syndromes 2. To encourage providers to obtain a thorough family history 3. To educate providers about available r...
      Speaker: Rinki Agarwal, MD FACOG,FACMG
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      4
      OCT 07, 2020 | 1:30 PM
      Artificial Intelligence in Digital Pathology
      Artificial Intelligence in Digital Pathology
      Join Branden Hopkinson, Product Marketing Manager at Visiopharm, who will talk about using AI classifiers to find patterns in your images and which artificial intelligence method will work b...
      Speaker: Branden Hopkinson, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Visiopharm®
      3
      OCT 07, 2020 | 12:00 AM
      Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of Futuristic Therapies
      Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of...
      Immune therapy approaches are being used in many different solid cancers today including clear cell renal carcinoma (mccRCC) and metastatic prostate adenocarcinoma. Over the past few years i...
      Speaker: Benjamin Maughan, MD, PharmD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      4
      SEP 23, 2020 | 11:30 AM
      Break-out: Setting Yourself Up for Core Success - A panel discussion
      Break-out: Setting Yourself Up for Core Success - A panel discussion
      Suspension by day, imaging by night: how to efficiently manage your system and optimize utilization Presented By: Jared K. Burks, PhD Mass cytometry, be it suspension or imaging, opens the d...
      Speaker: Jared K. Burks, PhD , Matthew Cochran, MS , Emily Thrash, PhD , Akil Merchant, MD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 23, 2020 | 8:00 AM
      CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic and Lab in Parallel
      CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic...
      Date: Time: Over the last couple of years, it has become apparent that affinity-tuned CAR T cells display enhanced expansion and prolonged persistence in patients and that this strategy can...
      Speaker: John Maher, PhD , Rogier Reijmers, PhD
      LUMICKS
      9 1
      SEP 16, 2020 | 9:00 AM
      Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
      Deep multi-omic phenotyping of biospecimens for immuno-oncology...
      Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
      Speaker: Dr. Shawn Fahl
      Sponsored By: Miltenyi Biotec
      11
      SEP 09, 2020 | 10:00 AM
      Immunoprotective vs. immunopathogenic responses during fungal-associated allergic airway inflammation
      Immunoprotective vs. immunopathogenic responses during fungal-associated...
      Asthma is an increasing health concern affecting more than 25 million individuals in the United States and more than 300 million individuals worldwide. In some cases, sensitization or exposu...
      Speaker: Chad Steele, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: Luminex - A DiaSorin Company
      1
      JUL 29, 2020 | 1:00 PM
      Using quantitative imaging microscopy to explore and target the molecular origins of cancer
      Using quantitative imaging microscopy to explore and target the...
      The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
      Speaker: Kirk McManus, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 07, 2020 | 10:30 AM
      Identification of human immune cell subtypes most vulnerable to IL-1β-induced inflammatory signaling using mass cytometry
      Identification of human immune cell subtypes most vulnerable to...
      Cytokine storm is suspected of producing the overzealous immune response driving the severe cardiopulmonary complications that fuel high morbidity and mortality rates in certain COVID-19 inf...
      Speaker: Hema Kothari, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      2
      JUL 07, 2020 | 9:30 AM
      Evaluating tumor-immune cell interactions in human lung cancer using multiparametric and spatially resolved tissue analysis
      Evaluating tumor-immune cell interactions in human lung cancer...
      ...
      Speaker: Kurt Schalper, MD, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
      JUN 03, 2020 | 1:00 PM
      Gene manipulation in primary human immune cells: Successful strategies and applications for CRISPRko, RNAi and beyond
      Gene manipulation in primary human immune cells: Successful strategies...
      Gene manipulation studies in primary human immune cells can answer important biological questions within a clinically relevant cellular context. In this webinar we explore the use of several...
      Speaker: Verena Brucklacher-Waldert, PhD
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: Horizon Discovery
      2
      JUN 03, 2020 | 12:00 PM
      Single cell multiomic analysis of T-cell exhaustion
      Single cell multiomic analysis of T-cell exhaustion
      A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
      Speaker: Pratip K. Chattopadhyay
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: BD
      2
      JUN 03, 2020 | 12:00 PM
      How multiplexed imaging reveals key insights into the tumor microenvironment to inform treatment and improve outcomes
      How multiplexed imaging reveals key insights into the tumor microenvironment...
      Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understanding of cells and their surroundings by providin...
      Speaker: Paul Goodwin , Fiona Ginty , Prachi Bogetto
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: Cytiva
      0
      MAY 27, 2020 | 8:00 AM
      How multiplexed imaging reveals key insights into the tumor microenvironment to inform treatment and improve outcomes
      How multiplexed imaging reveals key insights into the tumor microenvironment...
      DATE: May 27, 2020 TIME: 8:00am PT, 11:00am ET Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understand...
      Speaker: Paul Goodwin , Fiona Ginty , Prachi Bogetto
      Sponsored By: Cytiva
      18 2
      MAY 21, 2020 | 8:00 AM
      Accelerating gene editing research using the power of flow cytometry
      Accelerating gene editing research using the power of flow cytometry
      DATE: May 21, 2020 TIME: 8:00am PDT, 11:00am EDT The advent of CRISPR has radically changed the face and pace of biological research and has unlocked unprecedented potential in the study of...
      Speaker: Natasha Jacobsen
      Sponsored By: Thermo Fisher Scientific
      22 2
    FEB 03, 2021 | 12:30 PM
    Optimizing High-Content Imaging of 3D Models for Drug Discovery
    Optimizing High-Content Imaging of 3D Models for Drug Discovery
    In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
    Speaker: Arvonn Tully , Judi Wardwell-Swanson
    Presented at: 7th Annual Conference: SBI2 High Content
    Sponsored By: SBI2, InSphero , Yokogawa
    11 10
    DEC 16, 2020 | 7:00 AM
    The Impact of MBT Sepsityper®: The Lahey Experience
    The Impact of MBT Sepsityper®: The Lahey Experience
    Date: December 16, 2020 Time: 7:00am (PST), 10:00am (EST) During this webinar we will discuss the implementation and impact of the MALDI Biotyper® and the MBT Sepsityper® in the clinical mi...
    Speaker: Felicia Maida, GCertHSA, BS, MT(ASCP)
    Sponsored By: Bruker Microbiology & Infection Diagnostics
    6
    DEC 03, 2020 | 4:30 PM
    An Iterative Approach to Structure-based in silico to in vivo Development of Combinatorial Anti-SARS-CoV-2 Therapy
    An Iterative Approach to Structure-based in silico to in vivo...
    This drug development program is designed to create a family of broad-spectrum, pan-coronaviral drugs that respectively inhibit multiple key enzymes required for viral replication. By target...
    Speaker: Garth Ehrlich, PhD, FAAAS
    Presented at: Coronavirus Series
    5
    NOV 20, 2020 | 8:00 AM
    Efficiency to Confidence with High Resolution Accurate Mass Spectrometers: Analyzing IGF-1
    Efficiency to Confidence with High Resolution Accurate Mass Spectrometers:...
    DATE: November 20, 2020 TIME: 8am PDT, 11am EDT Insulin-like growth factor-1 (IGF-1) measurement by high-resolution accurate mass-mass spectrometry (HRAM) is replacing IGF-1 immunoassays and...
    Speaker: Tony Maus
    Sponsored By: Thermo Fisher Scientific
    7 1
    NOV 12, 2020 | 1:30 PM
    Covid-19 Testing and the role of Antigen assays today and moving forward
    Covid-19 Testing and the role of Antigen assays today and moving...
    Today's presentation will cover the following topics from the perspective of a NYC based Laboratory: What have we learned year to date about CoV-2 and specifically how diagnostic testing...
    Speaker: Vincent Streva, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: Diasorin
    1
     
     
  • OCT 29, 2020 | 8:00 AM
    Cell types to targets: Single cell RNA-sequencing for drug discovery
    Cell types to targets: Single cell RNA-sequencing for drug discovery
    Date: October 29, 2020 Time: 8:00am (PDT), 11:00am (EDT) What cell types cause and perpetuate disease? For many diseases, scientists only have guesses to this critical question. Single cell...
    Speaker: Sarah Middleton, PhD
    Sponsored By: 10x Genomics
    10 2
    OCT 29, 2020 | 6:00 AM
    Single-cell sequencing to investigate epigenetic mechanisms in inflammatory lymphocytes
    Single-cell sequencing to investigate epigenetic mechanisms in...
    Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
    Speaker: Thomas Ayers, Ph.D. , Pawel Zajac, Ph.D. , Dr. Adam Cribbs
    Sponsored By: Illumina, Dolomite Bio
    15
    OCT 08, 2020 | 7:30 AM
    Keynote Presentation: RNA Splicing and Ancestry-related Molecular Targets in Precision Oncology and Cancer Disparities
    Keynote Presentation: RNA Splicing and Ancestry-related Molecular...
    Individuals of under-represented minority ancestry are at disproportional risk for higher incidence and mortality rates for particular cancers. The unequal burden of cancer in certain racial...
    Speaker: Steven R. Patierno, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    4
    OCT 08, 2020 | 12:00 AM
    Hereditary Cancer Genetics
    Hereditary Cancer Genetics
    Learning Objectives: 1. To provide an overview of relevant hereditary cancer syndromes 2. To encourage providers to obtain a thorough family history 3. To educate providers about available r...
    Speaker: Rinki Agarwal, MD FACOG,FACMG
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    4
    OCT 07, 2020 | 1:30 PM
    Artificial Intelligence in Digital Pathology
    Artificial Intelligence in Digital Pathology
    Join Branden Hopkinson, Product Marketing Manager at Visiopharm, who will talk about using AI classifiers to find patterns in your images and which artificial intelligence method will work b...
    Speaker: Branden Hopkinson, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Visiopharm®
    3
     
     
  • OCT 07, 2020 | 12:00 AM
    Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of Futuristic Therapies
    Immunotherapy in Prostate and Renal Cell Carcinoma: Panoply of...
    Immune therapy approaches are being used in many different solid cancers today including clear cell renal carcinoma (mccRCC) and metastatic prostate adenocarcinoma. Over the past few years i...
    Speaker: Benjamin Maughan, MD, PharmD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    4
    SEP 23, 2020 | 11:30 AM
    Break-out: Setting Yourself Up for Core Success - A panel discussion
    Break-out: Setting Yourself Up for Core Success - A panel discussion
    Suspension by day, imaging by night: how to efficiently manage your system and optimize utilization Presented By: Jared K. Burks, PhD Mass cytometry, be it suspension or imaging, opens the d...
    Speaker: Jared K. Burks, PhD , Matthew Cochran, MS , Emily Thrash, PhD , Akil Merchant, MD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
    SEP 23, 2020 | 8:00 AM
    CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic and Lab in Parallel
    CAR T-Cell Immunotherapy of Solid Tumors - Learning from the Clinic...
    Date: Time: Over the last couple of years, it has become apparent that affinity-tuned CAR T cells display enhanced expansion and prolonged persistence in patients and that this strategy can...
    Speaker: John Maher, PhD , Rogier Reijmers, PhD
    LUMICKS
    9 1
    SEP 16, 2020 | 9:00 AM
    Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
    Deep multi-omic phenotyping of biospecimens for immuno-oncology...
    Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
    Speaker: Dr. Shawn Fahl
    Sponsored By: Miltenyi Biotec
    11
    SEP 09, 2020 | 10:00 AM
    Immunoprotective vs. immunopathogenic responses during fungal-associated allergic airway inflammation
    Immunoprotective vs. immunopathogenic responses during fungal-associated...
    Asthma is an increasing health concern affecting more than 25 million individuals in the United States and more than 300 million individuals worldwide. In some cases, sensitization or exposu...
    Speaker: Chad Steele, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: Luminex - A DiaSorin Company
    1
     
     
  • JUL 29, 2020 | 1:00 PM
    Using quantitative imaging microscopy to explore and target the molecular origins of cancer
    Using quantitative imaging microscopy to explore and target the...
    The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
    Speaker: Kirk McManus, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 07, 2020 | 10:30 AM
    Identification of human immune cell subtypes most vulnerable to IL-1β-induced inflammatory signaling using mass cytometry
    Identification of human immune cell subtypes most vulnerable to...
    Cytokine storm is suspected of producing the overzealous immune response driving the severe cardiopulmonary complications that fuel high morbidity and mortality rates in certain COVID-19 inf...
    Speaker: Hema Kothari, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    2
    JUL 07, 2020 | 9:30 AM
    Evaluating tumor-immune cell interactions in human lung cancer using multiparametric and spatially resolved tissue analysis
    Evaluating tumor-immune cell interactions in human lung cancer...
    ...
    Speaker: Kurt Schalper, MD, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    1
    JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
    JUN 03, 2020 | 1:00 PM
    Gene manipulation in primary human immune cells: Successful strategies and applications for CRISPRko, RNAi and beyond
    Gene manipulation in primary human immune cells: Successful strategies...
    Gene manipulation studies in primary human immune cells can answer important biological questions within a clinically relevant cellular context. In this webinar we explore the use of several...
    Speaker: Verena Brucklacher-Waldert, PhD
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: Horizon Discovery
    2
     
     
  • JUN 03, 2020 | 12:00 PM
    Single cell multiomic analysis of T-cell exhaustion
    Single cell multiomic analysis of T-cell exhaustion
    A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
    Speaker: Pratip K. Chattopadhyay
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: BD
    2
    JUN 03, 2020 | 12:00 PM
    How multiplexed imaging reveals key insights into the tumor microenvironment to inform treatment and improve outcomes
    How multiplexed imaging reveals key insights into the tumor microenvironment...
    Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understanding of cells and their surroundings by providin...
    Speaker: Paul Goodwin , Fiona Ginty , Prachi Bogetto
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: Cytiva
    0
    MAY 27, 2020 | 8:00 AM
    How multiplexed imaging reveals key insights into the tumor microenvironment to inform treatment and improve outcomes
    How multiplexed imaging reveals key insights into the tumor microenvironment...
    DATE: May 27, 2020 TIME: 8:00am PT, 11:00am ET Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understand...
    Speaker: Paul Goodwin , Fiona Ginty , Prachi Bogetto
    Sponsored By: Cytiva
    18 2
    MAY 21, 2020 | 8:00 AM
    Accelerating gene editing research using the power of flow cytometry
    Accelerating gene editing research using the power of flow cytometry
    DATE: May 21, 2020 TIME: 8:00am PDT, 11:00am EDT The advent of CRISPR has radically changed the face and pace of biological research and has unlocked unprecedented potential in the study of...
    Speaker: Natasha Jacobsen
    Sponsored By: Thermo Fisher Scientific
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