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    Target Identification

    Target Identification: is the process of identifying the direct molecular target - for example protein or nucleic acid - of a small molecule. In clinical pharmacology, target identification is aimed at finding the efficacy target of a drug/pharmaceutical or other xenobiotic. The techniques used may be based on principles of biochemistry, biophysics, genetics, chemical biology or other disciplines.

    Webinars

    • MAY 20, 2020 | 11:45 AM
      Lung Cancer Gene Fusion Assays using NanoString® nCounter® Technology
      Lung Cancer Gene Fusion Assays using NanoString® nCounter® Technology
      Personalized medicine has beomce a paradigm in lung cancer management; ~ 25–30% of advanced lung cancer patients could benefit from a targeted therapy. Several guidelines currently end...
      Speaker: Noemi Reguart, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 14, 2020 | 5:40 PM
      First experience with the Ion Torrent Genexus Workflow
      First experience with the Ion Torrent Genexus Workflow
      Operational barriers like complicated workflows and long turnaround times have hindered broad adoption of next-generation sequencing (NGS) in clinical oncology research. The new Ion Torrent...
      Speaker: Dr. Kojo Elenitoba-Johnson
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      6
      MAY 14, 2020 | 5:40 PM
      First experience with the Ion Torrent Genexus Workflow
      First experience with the Ion Torrent Genexus Workflow
      Learning Objectives: 1. Participants will become familiar with basic aspects of the user experience with the Genexus system 2. Participants will learn about preliminary studies using a targe...
      Speaker: Dr. Kojo Elenitoba-Johnson
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      MAY 14, 2020 | 3:00 PM
      Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
      Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
      Increasing evidence suggests that targeted sequencing of cell free DNA (cfDNA) can provide a comprehensive molecular portrait of solid tumors. However, the concordance between tissue and cfD...
      Speaker: Nicola Normanno, MD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      8
      MAY 14, 2020 | 3:00 PM
      Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
      Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
      Increasing evidence suggests that targeted sequencing of cell free DNA (cfDNA) can provide a comprehensive molecular portrait of solid tumors. However, the concordance between tissue and cfD...
      Speaker: Nicola Normanno, MD
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      MAY 13, 2020 | 9:00 AM
      Get Closer to the Truth: STELLARIS - Confocal Re-Imagined
      Get Closer to the Truth: STELLARIS - Confocal Re-Imagined
      DATE: May 13, 2020 TIME: 9:00am PT, 12:00pm ET STELLARIS. Confocal re-imagined. In microscopy, our mission is to empower you to drive progress in science. To get you closer to the truth, we...
      Speaker: Petra Haas, Ph.D. , Julia Roberti, Ph.D.
      Sponsored By: Leica Microsystems
      14
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      APR 29, 2020 | 9:00 AM
      The THUNDER Imager EM Cryo CLEM - How to identify and retrieve your cellular targets for Cryo Electron Microscopy
      The THUNDER Imager EM Cryo CLEM - How to identify and retrieve...
      DATE: April 29, 2020 TIME: 9:00am PT, 12:00pm ET Recent revolutionary developments in the field of cryo electron microscopy (EM) revealed cellular mechanisms in subnanometer resolution. Unfo...
      Speaker: Jan De Bock, PhD
      Sponsored By: Leica Microsystems
      10
      APR 29, 2020 | 8:00 AM
      Realize better NGS results through gentle cell sorting
      Realize better NGS results through gentle cell sorting
      Date: April 29, 2020 Time: 8:00AM PDT, 11:00AM EDT Single cell genomics and other next generation sequencing applications depend strongly on adequate upstream sample preparation. Results can...
      Speaker: Quy Nguyen , Felix Eppler, PhD
      Sponsored By: Miltenyi Biotec
      5 1
      APR 29, 2020 | 6:00 AM
      Direct Detection and Typing of Variety Pathogens Important for Human and Animal Health Using xMAP Technology
      Direct Detection and Typing of Variety Pathogens Important for...
      Background and aim: Rapid and complex diagnosis of viral, bacterial and parasitic infections is highly desirable not only in clinical practice, but also in food safety or early warning syste...
      Speaker: Petr Kralik, PhD
      Presented at: xMAP® Connect Virtual Conference (On-Demand)
      2
      APR 24, 2020 | 8:00 AM
      The International Council for Standardisation in Hematology (ICSH) recommendations for Hemostasis Critical Values, Tests, and Reporting - a stepwise description for the committee's decisions
      The International Council for Standardisation in Hematology (ICSH)...
      The International Council for Standardization in Haematology (ICSH) is a nonprofit organization dedicated to providing open-access guidance documents to enhance the quality of laboratory tes...
      Speaker: Bob Gosselin
      Sponsored By: Diagnostica Stago, Inc.
      10
      APR 24, 2020 | 8:00 AM
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
      DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
      Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
      Sponsored By: Bionano
      11
      APR 23, 2020 | 10:30 AM
      Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
      Keynote Presentation: Systematic identification of therapeutic...
      Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
      Speaker: Kris C. Wood, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 22, 2020 | 8:00 AM
      C.E. CREDITS
      The NEW Coag Value Playbook...Embrace the Power of Local Testing
      The NEW Coag Value Playbook...Embrace the Power of Local Testing
      Discover strategies for labs to optimize coagulation testing, improve patient outcomes, and strengthen their role in clinical care teams....
      Speaker: Eleanor Herriman, MD, MBA , Oksana Volod, MD
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      7
      APR 21, 2020 | 1:30 PM
      Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
      Spatially Resolved Molecular Investigation of Triple Negative...
      Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
      Speaker: Dina Finan, PhD , Stephen Williams, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 20, 2020 | 8:00 AM
      C.E. CREDITS
      Emergency patient management using coagulation assays
      Emergency patient management using coagulation assays
      Explore emergency hemostasis testing approaches, from rapid lab assays to viscoelastic methods, for managing bleeding patients....
      Speaker: Wayne Chandler, MD
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      17 5
      APR 02, 2020 | 8:00 AM
      Bionano Genome Imaging unravels complex structural rearrangements induced by replication stress in liver cancer
      Bionano Genome Imaging unravels complex structural rearrangements...
      DATE: April 2, 2020 TIME: 8:00am PT, 11:00am ET Cyclins A2 and E1 regulate the cell cycle by promoting S phase entry and progression. We recently identified a hepatocellular carcinoma (HCC)...
      Speaker: Eric Letouzé, PhD
      Sponsored By: Bionano
      14
      MAR 11, 2020 | 7:30 AM
      Keynote Presentation: Interplay between LRRK2 protein kinase and Rab GTPases in Parkinson's disease
      Keynote Presentation: Interplay between LRRK2 protein kinase and...
      Autosomal dominant missense mutations that hyperactivate the LRRK2 protein kinase are a common cause of inherited Parkinson’s disease and therapeutic efficacy of LRRK2 inhibitors is be...
      Speaker: Dario Alessi, FRS FMedSci FRSE
      Presented at: Neuroscience Virtual Event Series 2020
      1
      FEB 05, 2020 | 8:00 AM
      C.E. CREDITS
      Emerging Issues in the Coagulation Laboratory
      Emerging Issues in the Coagulation Laboratory
      Learn how new hemophilia and anticoagulant therapies impact coagulation assays and clinical decisions in our educational session....
      Speaker: Donna Castellone, MS, MASCP, MT(ASCP) SH
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      10 1
      JAN 01, 2020 | 6:00 AM
      Organoids: A Revolutionary New Tool for Drug Screening
      Organoids: A Revolutionary New Tool for Drug Screening
      “The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
      Speaker: Rekha Pal, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      OCT 24, 2019 | 10:30 AM
      Supercritical fluid chromatography of polar biomolecules at the analytical and preparative scale: evaluation of global conformational changes in peptides and proteins
      Supercritical fluid chromatography of polar biomolecules at the...
      Supercritical fluid chromatography (SFC) has historically been very effective for exacting difficult chiral separations, with an unmatched power in terms of enabling highly efficient enantios...
      Speaker: Raffeal Bennett, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      2
      SEP 11, 2019 | 1:30 PM
      Development of Machine Learning Algorithms to Data Mine Meta-Omic Characterizations of Complex Microbiota
      Development of Machine Learning Algorithms to Data Mine Meta-Omic...
      Background: The vast majority of all genes are contained within the genomes of the prokaryotes, including the eubacteria and the archaea. These largely single-cellular domains of life thus...
      Speaker: Garth Ehrlich, PhD, FAAAS
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      Sponsored By: PacBio
      4
      MAY 22, 2019 | 8:00 AM
      Improving lipidomics performance -- a view through a local lens
      Improving lipidomics performance -- a view through a local lens
      DATE: May 22, 2019TIME: 08:00am PDTOmics analysis offers the potential to obtain deep insight into biological processes as well as a rich source of potential biomarkers. While the consu...
      Speaker: Bruce Kristal
      Sponsored By: Agilent
      3
      MAY 09, 2019 | 12:00 PM
      A Metagenomic Assay to Interrogate the Role of Virome and Microbiome in Cancer
      A Metagenomic Assay to Interrogate the Role of Virome and Microbiome...
      Screening to identify all known viruses and other pathogenic microorganisms including bacteria, fungus and parasites in human tumor tissues will provide a more comprehensive understanding of...
      Speaker: Erle Robertson, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: Agilent
      3
    MAY 20, 2020 | 11:45 AM
    Lung Cancer Gene Fusion Assays using NanoString® nCounter® Technology
    Lung Cancer Gene Fusion Assays using NanoString® nCounter® Technology
    Personalized medicine has beomce a paradigm in lung cancer management; ~ 25–30% of advanced lung cancer patients could benefit from a targeted therapy. Several guidelines currently end...
    Speaker: Noemi Reguart, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 14, 2020 | 5:40 PM
    First experience with the Ion Torrent Genexus Workflow
    First experience with the Ion Torrent Genexus Workflow
    Operational barriers like complicated workflows and long turnaround times have hindered broad adoption of next-generation sequencing (NGS) in clinical oncology research. The new Ion Torrent...
    Speaker: Dr. Kojo Elenitoba-Johnson
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    6
    MAY 14, 2020 | 5:40 PM
    First experience with the Ion Torrent Genexus Workflow
    First experience with the Ion Torrent Genexus Workflow
    Learning Objectives: 1. Participants will become familiar with basic aspects of the user experience with the Genexus system 2. Participants will learn about preliminary studies using a targe...
    Speaker: Dr. Kojo Elenitoba-Johnson
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    MAY 14, 2020 | 3:00 PM
    Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
    Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
    Increasing evidence suggests that targeted sequencing of cell free DNA (cfDNA) can provide a comprehensive molecular portrait of solid tumors. However, the concordance between tissue and cfD...
    Speaker: Nicola Normanno, MD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    8
    MAY 14, 2020 | 3:00 PM
    Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
    Analysis of Solid Tumor Genomic Landscape in Liquid Biopsy
    Increasing evidence suggests that targeted sequencing of cell free DNA (cfDNA) can provide a comprehensive molecular portrait of solid tumors. However, the concordance between tissue and cfD...
    Speaker: Nicola Normanno, MD
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
     
     
  • MAY 13, 2020 | 9:00 AM
    Get Closer to the Truth: STELLARIS - Confocal Re-Imagined
    Get Closer to the Truth: STELLARIS - Confocal Re-Imagined
    DATE: May 13, 2020 TIME: 9:00am PT, 12:00pm ET STELLARIS. Confocal re-imagined. In microscopy, our mission is to empower you to drive progress in science. To get you closer to the truth, we...
    Speaker: Petra Haas, Ph.D. , Julia Roberti, Ph.D.
    Sponsored By: Leica Microsystems
    14
    MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
    APR 29, 2020 | 9:00 AM
    The THUNDER Imager EM Cryo CLEM - How to identify and retrieve your cellular targets for Cryo Electron Microscopy
    The THUNDER Imager EM Cryo CLEM - How to identify and retrieve...
    DATE: April 29, 2020 TIME: 9:00am PT, 12:00pm ET Recent revolutionary developments in the field of cryo electron microscopy (EM) revealed cellular mechanisms in subnanometer resolution. Unfo...
    Speaker: Jan De Bock, PhD
    Sponsored By: Leica Microsystems
    10
    APR 29, 2020 | 8:00 AM
    Realize better NGS results through gentle cell sorting
    Realize better NGS results through gentle cell sorting
    Date: April 29, 2020 Time: 8:00AM PDT, 11:00AM EDT Single cell genomics and other next generation sequencing applications depend strongly on adequate upstream sample preparation. Results can...
    Speaker: Quy Nguyen , Felix Eppler, PhD
    Sponsored By: Miltenyi Biotec
    5 1
    APR 29, 2020 | 6:00 AM
    Direct Detection and Typing of Variety Pathogens Important for Human and Animal Health Using xMAP Technology
    Direct Detection and Typing of Variety Pathogens Important for...
    Background and aim: Rapid and complex diagnosis of viral, bacterial and parasitic infections is highly desirable not only in clinical practice, but also in food safety or early warning syste...
    Speaker: Petr Kralik, PhD
    Presented at: xMAP® Connect Virtual Conference (On-Demand)
    2
     
     
  • APR 24, 2020 | 8:00 AM
    The International Council for Standardisation in Hematology (ICSH) recommendations for Hemostasis Critical Values, Tests, and Reporting - a stepwise description for the committee's decisions
    The International Council for Standardisation in Hematology (ICSH)...
    The International Council for Standardization in Haematology (ICSH) is a nonprofit organization dedicated to providing open-access guidance documents to enhance the quality of laboratory tes...
    Speaker: Bob Gosselin
    Sponsored By: Diagnostica Stago, Inc.
    10
    APR 24, 2020 | 8:00 AM
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
    DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
    Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
    Sponsored By: Bionano
    11
    APR 23, 2020 | 10:30 AM
    Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
    Keynote Presentation: Systematic identification of therapeutic...
    Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
    Speaker: Kris C. Wood, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 22, 2020 | 8:00 AM
    C.E. CREDITS
    The NEW Coag Value Playbook...Embrace the Power of Local Testing
    The NEW Coag Value Playbook...Embrace the Power of Local Testing
    Discover strategies for labs to optimize coagulation testing, improve patient outcomes, and strengthen their role in clinical care teams....
    Speaker: Eleanor Herriman, MD, MBA , Oksana Volod, MD
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
    7
    APR 21, 2020 | 1:30 PM
    Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
    Spatially Resolved Molecular Investigation of Triple Negative...
    Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
    Speaker: Dina Finan, PhD , Stephen Williams, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
     
     
  • APR 20, 2020 | 8:00 AM
    C.E. CREDITS
    Emergency patient management using coagulation assays
    Emergency patient management using coagulation assays
    Explore emergency hemostasis testing approaches, from rapid lab assays to viscoelastic methods, for managing bleeding patients....
    Speaker: Wayne Chandler, MD
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
    17 5
    APR 02, 2020 | 8:00 AM
    Bionano Genome Imaging unravels complex structural rearrangements induced by replication stress in liver cancer
    Bionano Genome Imaging unravels complex structural rearrangements...
    DATE: April 2, 2020 TIME: 8:00am PT, 11:00am ET Cyclins A2 and E1 regulate the cell cycle by promoting S phase entry and progression. We recently identified a hepatocellular carcinoma (HCC)...
    Speaker: Eric Letouzé, PhD
    Sponsored By: Bionano
    14
    MAR 11, 2020 | 7:30 AM
    Keynote Presentation: Interplay between LRRK2 protein kinase and Rab GTPases in Parkinson's disease
    Keynote Presentation: Interplay between LRRK2 protein kinase and...
    Autosomal dominant missense mutations that hyperactivate the LRRK2 protein kinase are a common cause of inherited Parkinson’s disease and therapeutic efficacy of LRRK2 inhibitors is be...
    Speaker: Dario Alessi, FRS FMedSci FRSE
    Presented at: Neuroscience Virtual Event Series 2020
    1
    FEB 05, 2020 | 8:00 AM
    C.E. CREDITS
    Emerging Issues in the Coagulation Laboratory
    Emerging Issues in the Coagulation Laboratory
    Learn how new hemophilia and anticoagulant therapies impact coagulation assays and clinical decisions in our educational session....
    Speaker: Donna Castellone, MS, MASCP, MT(ASCP) SH
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
    10 1
    JAN 01, 2020 | 6:00 AM
    Organoids: A Revolutionary New Tool for Drug Screening
    Organoids: A Revolutionary New Tool for Drug Screening
    “The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
    Speaker: Rekha Pal, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
     
     
  • OCT 24, 2019 | 10:30 AM
    Supercritical fluid chromatography of polar biomolecules at the analytical and preparative scale: evaluation of global conformational changes in peptides and proteins
    Supercritical fluid chromatography of polar biomolecules at the...
    Supercritical fluid chromatography (SFC) has historically been very effective for exacting difficult chiral separations, with an unmatched power in terms of enabling highly efficient enantios...
    Speaker: Raffeal Bennett, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    2
    SEP 11, 2019 | 1:30 PM
    Development of Machine Learning Algorithms to Data Mine Meta-Omic Characterizations of Complex Microbiota
    Development of Machine Learning Algorithms to Data Mine Meta-Omic...
    Background: The vast majority of all genes are contained within the genomes of the prokaryotes, including the eubacteria and the archaea. These largely single-cellular domains of life thus...
    Speaker: Garth Ehrlich, PhD, FAAAS
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    Sponsored By: PacBio
    4
    MAY 22, 2019 | 8:00 AM
    Improving lipidomics performance -- a view through a local lens
    Improving lipidomics performance -- a view through a local lens
    DATE: May 22, 2019TIME: 08:00am PDTOmics analysis offers the potential to obtain deep insight into biological processes as well as a rich source of potential biomarkers. While the consu...
    Speaker: Bruce Kristal
    Sponsored By: Agilent
    3
    MAY 09, 2019 | 12:00 PM
    A Metagenomic Assay to Interrogate the Role of Virome and Microbiome in Cancer
    A Metagenomic Assay to Interrogate the Role of Virome and Microbiome...
    Screening to identify all known viruses and other pathogenic microorganisms including bacteria, fungus and parasites in human tumor tissues will provide a more comprehensive understanding of...
    Speaker: Erle Robertson, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: Agilent
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