Transgenic is a term that describes an organism containing genes from another organism put into its genome through recombinant DNA techniques. An example of its usage is the term transgenic organism. A transgenic organism is one that contains a gene or genes which have been artificially inserted instead of the organism acquiring them through reproduction. A transgenic animal, for instance, would be an animal that underwent genetic engineering. It often contains material from at least one unrelated organism, e.g. from a virus, a plant, or from another animal. The process of introducing an exogenous gene is called transgenesis. One of its essential applications is for experimental research processes. Animal models are being created to introduce a particular disease for experimental studies. These models are referred to as transgenic disease models. Experimental mouse model, particularly referred to as transgenic mouse, is a mouse with a piece of foreign lincor DNA integrated into its genome through recombinant DNA techniques.
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Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
The RNA-guided nuclease Cas9 from the microbial CRISPR adaptive immune system has emerged as an exciting tool for precise genome editing in eukaryotic cells. This presentation will discuss th...
Huntington's disease (HD) is a progressive, inherited, degenerative brain disorder that produces physical, mental and emotional changes. Named for George Huntington, the physician who fi...
ATP-binding cassette transporter A1 (ABCA1) mediates cholesterol efflux to lipid-free apolipoproteins such as apolipoprotein A-I (apoA-I) and apolipoprotein E (apoE). ABCA1 is essential regul...
The rise of zebrafish as a research model has been dramatic. Given the global nature of the work, the rise in shipping zebrafish as a laboratory species has been sharp. Up until this point th...
The popularity reached by the genetic manipulation of laboratory animals to create new models for studying human diseases, produced in turn, that the techniques for assisted reproduction cons...
FEB 05, 2014 | 3:00 PM
C.E. CREDITS
The title of this presentation could have been Training within laboratory animal science - where we are and where we should be. While training has been the domain of facility managers for ma...
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