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    Upstream Processing

    Upstream Processing: is the first step in which biomolecules are grown in bioreactors. When they reach the desired density they are harvested and moved to the downstream section of the bioprocess.

    Webinars

    • NOV 15, 2023 | 10:00 AM
      Untangling Automated Proteomics
      Untangling Automated Proteomics
      Join our webinar to discover how automated sample preparation can free your lab from the time-consuming, costly, and complex manual workflows in proteomics. In the ever-evolving field of pro...
      Speaker: Dr. Sudha Savant
      Sponsored By: Beckman Coulter Life Sciences
      10
      FEB 02, 2023 | 11:00 AM
      Break the Bottleneck: Automate Plasmid Maxi-prep with AmMagâ„¢ Quatro
      Break the Bottleneck: Automate Plasmid Maxi-prep with AmMagâ„¢ Quatro
      Date: December 13, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CEST) Plasmid DNA (pDNA) is an essential component of molecular biotechnology applications, such as protein expression and...
      Speaker: Rouba Najjar, MBA
      Sponsored By: GenScript
      11 1
      DEC 07, 2022 | 8:00 AM
      Automation & Optimization Technology for Bioprocessing Operations
      Automation & Optimization Technology for Bioprocessing Operations
      Date: December 7, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Join Tom Fletcher, Scientific Director, Research and Development, and Guy Matthews, Director of Single Use Technologie...
      Speaker: Tom Fletcher , Guy Matthews
      Sponsored By: FUJIFILM Irvine Scientific
      16
      JUN 22, 2022 | 8:00 AM
      Delivering Improved Bioprocessing Workflows: The Manufacturing Science and Technology (MSAT) Service
      Delivering Improved Bioprocessing Workflows: The Manufacturing...
      Date: June 22, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Join us as we discuss the new Manufacturing Science and Technology (MSAT) Service offering, created in response to the nee...
      Speaker: Tom Fletcher , Michael De La Cruz, Ph.D.
      Sponsored By: FUJIFILM Irvine Scientific
      11
      MAY 18, 2022 | 9:00 AM
      Panel Presentation: Concept-to-Commercialization: Thermo Fisher's Unique Approach to Rapidly Advancing Your Antibody and Protein Therapeutics
      Panel Presentation: Concept-to-Commercialization: Thermo Fisher's...
      Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. The ability to swiftly develop novel therapies often depends...
      Speaker: Steve Lewis , Jeff Hou, PhD
      Presented at: Laboratory Automation Virtual Event Series 2022
      Sponsored By: Thermo Fisher Scientific
      1
      APR 20, 2022 | 12:00 PM
      Panel Presentation: Concept-to-Commercialization: Thermo Fisher's Unique Approach to Rapidly Advancing Your Antibody and Protein Therapeutics
      Panel Presentation: Concept-to-Commercialization: Thermo Fisher's...
      Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. The ability to swiftly develop novel therapies often depends...
      Speaker: Steve Lewis , Jeff Hou, PhD
      Presented at: Genetics Week Virtual Event Series 2022
      Sponsored By: Thermo Fisher Scientific
      1
      SEP 22, 2021 | 7:30 AM
      Panel Presentation: Concept-to-Commercialization: Thermo Fisher's Unique Approach to Rapidly Advancing Your Antibody and Protein Therapeutics
      Panel Presentation: Concept-to-Commercialization: Thermo Fisher's...
      Date: September 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. T...
      Speaker: Jeff Hou, PhD , Steve Lewis
      Presented at: Cell Biology Virtual Event Series 2021
      Sponsored By: Thermo Fisher Scientific
      0
      SEP 16, 2021 | 8:00 AM
      Concept-to-Commercialization: Thermo Fisher's unique approach to rapidly advancing your antibody and protein therapeutics
      Concept-to-Commercialization: Thermo Fisher's unique approach...
      Date: September 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. T...
      Speaker: Jeff Hou, PhD , Steve Lewis
      Sponsored By: Thermo Fisher Scientific
      1
      JUN 03, 2021 | 12:00 PM
      Utilizing the Gibco CTS Rotea System for cell and gene therapy development
      Utilizing the Gibco CTS Rotea System for cell and gene therapy...
      DATE: June 3, 2021 TIME: 12:00pm SGT This webinar is a virtual event that focuses on utilizing the Gibco CTS Rotea System for Cell and Gene Therapy...
      Speaker: Premkumar Jayaraman, PhD , Emily Benz , Eric Dubofsky
      Sponsored By: Thermo Fisher Scientific
      5
      APR 07, 2021 | 9:00 AM
      Keynote Presentation: Doing more with less - Maximizing Phase Appropriate DOE Strategies
      Keynote Presentation: Doing more with less - Maximizing Phase...
      One challenge pharmaceutical companies face, is moving promising biotherapeutic products into the clinic as fast as safely possible. Devoting the correct amount of time and resources to earl...
      Speaker: Patricia McNeill
      Presented at: Bioprocessing Virtual Event Series 2021
      Sponsored By: Roche Diagnostics
      1
      APR 07, 2021 | 12:00 AM
      Model-Based Design of Mammalian Cell Culture Media: Demonstration for GS-NS0 Cell Line
      Model-Based Design of Mammalian Cell Culture Media: Demonstration...
      Demand for high-value biologics, a rapidly growing pipeline, and pressure from competition, time-to-market and regulators, necessitate novel biomanufacturing approaches, including Quality by...
      Speaker: Sakis Mantalaris, PhD, FAIMBE
      Presented at: Bioprocessing Virtual Event Series 2021
      1
      SEP 23, 2020 | 4:30 PM
      Anatomy of a nucleic acid sample preparation
      Anatomy of a nucleic acid sample preparation
      There are many methods of nucleic acid isolation. Each technology offers different approaches of purification of the template. However, it is important to control carry over of “proces...
      Speaker: Katherine Mechling
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2 1
      SEP 10, 2020 | 9:00 AM
      An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
      An Insider's Look: How One Parameter Can Optimize Key Phases of...
      Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
      Speaker: Tara Barreira , Kristeena Wright
      Sponsored By: Advanced Instruments
      7
      JUN 02, 2020 | 9:00 AM
      Osmolality Testing: Providing Unique Process Control for Downstream Operations
      Osmolality Testing: Providing Unique Process Control for Downstream...
      DATE: June 2, 2020 TIME: 9:00am PT, 12:00pm ET Osmolality is a well-established parameter for upstream bioprocessing, formulation, analytical development and QC applications throughout the m...
      Speaker: Alois Jungbauer, PhD , Kristeena Wright, PhD
      Sponsored By: Advanced Instruments
      11 1
      APR 08, 2020 | 9:00 AM
      Case Study: From Ligand discovery to developing a purification platform and delivering GMP-ready affinity chromatography columns
      Case Study: From Ligand discovery to developing a purification...
      This presentation is about a client-focused approach used to find an all synthetic ligand which is developed into an affinity adsorbent – followed by working with the client to develop...
      Speaker: Buzz Lobbezoo
      Presented at: BioProcessing Virtual Event Series 2020
      1
      APR 08, 2020 | 7:30 AM
      Keynote Presentation: New Paradigms in moving toward Point-of-Care Cell Therapy Services in the Hospital
      Keynote Presentation: New Paradigms in moving toward Point-of-Care...
      Genetically-modified cell therapies are revolutionizing medicine, offering new opportunities to treat cancer patients and potentially many other diseases. The process of producing gene-modif...
      Speaker: Robert Kruse, MD, PhD
      Presented at: BioProcessing Virtual Event Series 2020
      1
      APR 08, 2020 | 12:00 AM
      Collaborative Education for Talent of the Future
      Collaborative Education for Talent of the Future
      Strong performance for a Facility of the Future for the Life Sciences industry requires more than optimal manufacturing process development and facility design. The sector encompasses a dive...
      Speaker: Sue Behrens
      Presented at: BioProcessing Virtual Event Series 2020
      1
      APR 08, 2020 | 12:00 AM
      The NISTmAb and Related Biopharmaceutical Resources
      The NISTmAb and Related Biopharmaceutical Resources
      The NIST Biomanufacturing Program develops measurement science, standards, reference data and tools to support the development, manufacturing, and regulatory approval of biologic medicines....
      Speaker: John Schiel, PhD
      Presented at: BioProcessing Virtual Event Series 2020
      1
      APR 08, 2020 | 12:00 AM
      Droplet Digital PCR as a tool for gene therapy application
      Droplet Digital PCR as a tool for gene therapy application
      Digital PCR has become the emerging technique for the sequence-specific detection and quantification of nucleic acids for various applications. During the recent years, numerous articles of...
      Speaker: Nagarjun Kasaraneni, PhD
      Presented at: BioProcessing Virtual Event Series 2020
      1
      APR 08, 2020 | 12:00 AM
      Macroscopic Modeling of Bioreactors for Recombinant Protein Producing Pichia pastoris in Defined Medium
      Macroscopic Modeling of Bioreactors for Recombinant Protein Producing...
      Bioreactor modeling can inform understanding of cellular metabolism—including aspects of growth kinetics, productivity, media consumption, and metabolite secretion—and can be use...
      Speaker: Moo Sun Hong, MS
      Presented at: BioProcessing Virtual Event Series 2020
      2
      APR 08, 2020 | 12:00 AM
      Hybrid Modeling and Intensified DoE Enabling Faster Process Development, Soft Sensors and Model Predictive Control
      Hybrid Modeling and Intensified DoE Enabling Faster Process Development,...
      Within this talk the advantages of using intensified Design of experiments (iDoE) in combination with hybrid modeling will be demonstrated. In detailed upstream and downstream showcases the...
      Speaker: Mark Dürkop, PhD
      Presented at: BioProcessing Virtual Event Series 2020
      1 1
      APR 08, 2020 | 12:00 AM
      Directed Evolution of Next-Generation AAV Vector Systems for Clinical Gene Therapy
      Directed Evolution of Next-Generation AAV Vector Systems for Clinical...
      There has been an increasing number of successful gene therapy clinical trials, leading to regulatory approvals of numerous gene therapy products, in particular ones based on the adeno-assoc...
      Speaker: David Schaffer, PhD
      Presented at: BioProcessing Virtual Event Series 2020
      2
      MAR 11, 2020 | 1:30 PM
      PANEL: Dissecting the circuit logics in the amygdala underlying emotional learning
      PANEL: Dissecting the circuit logics in the amygdala underlying...
      Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
      Speaker: Bo Li , Tianyi Mao , Haining Zhong
      Presented at: Neuroscience Virtual Event Series 2020
      1
      JUN 26, 2019 | 10:00 AM
      Factors to Consider During Adaptation of a Manual Cell Line Development Workflow to Automation
      Factors to Consider During Adaptation of a Manual Cell Line Development...
      DATE: June 26, 2019TIME: 10:00am PDTMammalian cell line generation is a rate-limiting step in early CMC development and there is a constant desire to increase throughput. The implem...
      Speaker: Rob Ballinger
      Sponsored By: Beckman Coulter Life Sciences
      4
    NOV 15, 2023 | 10:00 AM
    Untangling Automated Proteomics
    Untangling Automated Proteomics
    Join our webinar to discover how automated sample preparation can free your lab from the time-consuming, costly, and complex manual workflows in proteomics. In the ever-evolving field of pro...
    Speaker: Dr. Sudha Savant
    Sponsored By: Beckman Coulter Life Sciences
    10
    FEB 02, 2023 | 11:00 AM
    Break the Bottleneck: Automate Plasmid Maxi-prep with AmMagâ„¢ Quatro
    Break the Bottleneck: Automate Plasmid Maxi-prep with AmMagâ„¢ Quatro
    Date: December 13, 2022 Time: 11:00am (PST), 2:00pm (EST), 8:00pm (CEST) Plasmid DNA (pDNA) is an essential component of molecular biotechnology applications, such as protein expression and...
    Speaker: Rouba Najjar, MBA
    Sponsored By: GenScript
    11 1
    DEC 07, 2022 | 8:00 AM
    Automation & Optimization Technology for Bioprocessing Operations
    Automation & Optimization Technology for Bioprocessing Operations
    Date: December 7, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Join Tom Fletcher, Scientific Director, Research and Development, and Guy Matthews, Director of Single Use Technologie...
    Speaker: Tom Fletcher , Guy Matthews
    Sponsored By: FUJIFILM Irvine Scientific
    16
    JUN 22, 2022 | 8:00 AM
    Delivering Improved Bioprocessing Workflows: The Manufacturing Science and Technology (MSAT) Service
    Delivering Improved Bioprocessing Workflows: The Manufacturing...
    Date: June 22, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Join us as we discuss the new Manufacturing Science and Technology (MSAT) Service offering, created in response to the nee...
    Speaker: Tom Fletcher , Michael De La Cruz, Ph.D.
    Sponsored By: FUJIFILM Irvine Scientific
    11
    MAY 18, 2022 | 9:00 AM
    Panel Presentation: Concept-to-Commercialization: Thermo Fisher's Unique Approach to Rapidly Advancing Your Antibody and Protein Therapeutics
    Panel Presentation: Concept-to-Commercialization: Thermo Fisher's...
    Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. The ability to swiftly develop novel therapies often depends...
    Speaker: Steve Lewis , Jeff Hou, PhD
    Presented at: Laboratory Automation Virtual Event Series 2022
    Sponsored By: Thermo Fisher Scientific
    1
     
     
  • APR 20, 2022 | 12:00 PM
    Panel Presentation: Concept-to-Commercialization: Thermo Fisher's Unique Approach to Rapidly Advancing Your Antibody and Protein Therapeutics
    Panel Presentation: Concept-to-Commercialization: Thermo Fisher's...
    Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. The ability to swiftly develop novel therapies often depends...
    Speaker: Steve Lewis , Jeff Hou, PhD
    Presented at: Genetics Week Virtual Event Series 2022
    Sponsored By: Thermo Fisher Scientific
    1
    SEP 22, 2021 | 7:30 AM
    Panel Presentation: Concept-to-Commercialization: Thermo Fisher's Unique Approach to Rapidly Advancing Your Antibody and Protein Therapeutics
    Panel Presentation: Concept-to-Commercialization: Thermo Fisher's...
    Date: September 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. T...
    Speaker: Jeff Hou, PhD , Steve Lewis
    Presented at: Cell Biology Virtual Event Series 2021
    Sponsored By: Thermo Fisher Scientific
    0
    SEP 16, 2021 | 8:00 AM
    Concept-to-Commercialization: Thermo Fisher's unique approach to rapidly advancing your antibody and protein therapeutics
    Concept-to-Commercialization: Thermo Fisher's unique approach...
    Date: September 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. T...
    Speaker: Jeff Hou, PhD , Steve Lewis
    Sponsored By: Thermo Fisher Scientific
    1
    JUN 03, 2021 | 12:00 PM
    Utilizing the Gibco CTS Rotea System for cell and gene therapy development
    Utilizing the Gibco CTS Rotea System for cell and gene therapy...
    DATE: June 3, 2021 TIME: 12:00pm SGT This webinar is a virtual event that focuses on utilizing the Gibco CTS Rotea System for Cell and Gene Therapy...
    Speaker: Premkumar Jayaraman, PhD , Emily Benz , Eric Dubofsky
    Sponsored By: Thermo Fisher Scientific
    5
    APR 07, 2021 | 9:00 AM
    Keynote Presentation: Doing more with less - Maximizing Phase Appropriate DOE Strategies
    Keynote Presentation: Doing more with less - Maximizing Phase...
    One challenge pharmaceutical companies face, is moving promising biotherapeutic products into the clinic as fast as safely possible. Devoting the correct amount of time and resources to earl...
    Speaker: Patricia McNeill
    Presented at: Bioprocessing Virtual Event Series 2021
    Sponsored By: Roche Diagnostics
    1
     
     
  • APR 07, 2021 | 12:00 AM
    Model-Based Design of Mammalian Cell Culture Media: Demonstration for GS-NS0 Cell Line
    Model-Based Design of Mammalian Cell Culture Media: Demonstration...
    Demand for high-value biologics, a rapidly growing pipeline, and pressure from competition, time-to-market and regulators, necessitate novel biomanufacturing approaches, including Quality by...
    Speaker: Sakis Mantalaris, PhD, FAIMBE
    Presented at: Bioprocessing Virtual Event Series 2021
    1
    SEP 23, 2020 | 4:30 PM
    Anatomy of a nucleic acid sample preparation
    Anatomy of a nucleic acid sample preparation
    There are many methods of nucleic acid isolation. Each technology offers different approaches of purification of the template. However, it is important to control carry over of “proces...
    Speaker: Katherine Mechling
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2 1
    SEP 10, 2020 | 9:00 AM
    An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
    An Insider's Look: How One Parameter Can Optimize Key Phases of...
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    Speaker: Tara Barreira , Kristeena Wright
    Sponsored By: Advanced Instruments
    7
    JUN 02, 2020 | 9:00 AM
    Osmolality Testing: Providing Unique Process Control for Downstream Operations
    Osmolality Testing: Providing Unique Process Control for Downstream...
    DATE: June 2, 2020 TIME: 9:00am PT, 12:00pm ET Osmolality is a well-established parameter for upstream bioprocessing, formulation, analytical development and QC applications throughout the m...
    Speaker: Alois Jungbauer, PhD , Kristeena Wright, PhD
    Sponsored By: Advanced Instruments
    11 1
    APR 08, 2020 | 9:00 AM
    Case Study: From Ligand discovery to developing a purification platform and delivering GMP-ready affinity chromatography columns
    Case Study: From Ligand discovery to developing a purification...
    This presentation is about a client-focused approach used to find an all synthetic ligand which is developed into an affinity adsorbent – followed by working with the client to develop...
    Speaker: Buzz Lobbezoo
    Presented at: BioProcessing Virtual Event Series 2020
    1
     
     
  • APR 08, 2020 | 7:30 AM
    Keynote Presentation: New Paradigms in moving toward Point-of-Care Cell Therapy Services in the Hospital
    Keynote Presentation: New Paradigms in moving toward Point-of-Care...
    Genetically-modified cell therapies are revolutionizing medicine, offering new opportunities to treat cancer patients and potentially many other diseases. The process of producing gene-modif...
    Speaker: Robert Kruse, MD, PhD
    Presented at: BioProcessing Virtual Event Series 2020
    1
    APR 08, 2020 | 12:00 AM
    Collaborative Education for Talent of the Future
    Collaborative Education for Talent of the Future
    Strong performance for a Facility of the Future for the Life Sciences industry requires more than optimal manufacturing process development and facility design. The sector encompasses a dive...
    Speaker: Sue Behrens
    Presented at: BioProcessing Virtual Event Series 2020
    1
    APR 08, 2020 | 12:00 AM
    The NISTmAb and Related Biopharmaceutical Resources
    The NISTmAb and Related Biopharmaceutical Resources
    The NIST Biomanufacturing Program develops measurement science, standards, reference data and tools to support the development, manufacturing, and regulatory approval of biologic medicines....
    Speaker: John Schiel, PhD
    Presented at: BioProcessing Virtual Event Series 2020
    1
    APR 08, 2020 | 12:00 AM
    Droplet Digital PCR as a tool for gene therapy application
    Droplet Digital PCR as a tool for gene therapy application
    Digital PCR has become the emerging technique for the sequence-specific detection and quantification of nucleic acids for various applications. During the recent years, numerous articles of...
    Speaker: Nagarjun Kasaraneni, PhD
    Presented at: BioProcessing Virtual Event Series 2020
    1
    APR 08, 2020 | 12:00 AM
    Macroscopic Modeling of Bioreactors for Recombinant Protein Producing Pichia pastoris in Defined Medium
    Macroscopic Modeling of Bioreactors for Recombinant Protein Producing...
    Bioreactor modeling can inform understanding of cellular metabolism—including aspects of growth kinetics, productivity, media consumption, and metabolite secretion—and can be use...
    Speaker: Moo Sun Hong, MS
    Presented at: BioProcessing Virtual Event Series 2020
    2
     
     
  • APR 08, 2020 | 12:00 AM
    Hybrid Modeling and Intensified DoE Enabling Faster Process Development, Soft Sensors and Model Predictive Control
    Hybrid Modeling and Intensified DoE Enabling Faster Process Development,...
    Within this talk the advantages of using intensified Design of experiments (iDoE) in combination with hybrid modeling will be demonstrated. In detailed upstream and downstream showcases the...
    Speaker: Mark Dürkop, PhD
    Presented at: BioProcessing Virtual Event Series 2020
    1 1
    APR 08, 2020 | 12:00 AM
    Directed Evolution of Next-Generation AAV Vector Systems for Clinical Gene Therapy
    Directed Evolution of Next-Generation AAV Vector Systems for Clinical...
    There has been an increasing number of successful gene therapy clinical trials, leading to regulatory approvals of numerous gene therapy products, in particular ones based on the adeno-assoc...
    Speaker: David Schaffer, PhD
    Presented at: BioProcessing Virtual Event Series 2020
    2
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    PANEL: Dissecting the circuit logics in the amygdala underlying emotional learning
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    Speaker: Bo Li , Tianyi Mao , Haining Zhong
    Presented at: Neuroscience Virtual Event Series 2020
    1
    JUN 26, 2019 | 10:00 AM
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    Sponsored By: Beckman Coulter Life Sciences
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