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Asymptomatic SARS-CoV-2 infection and delayed implementation of diagnostics have led to poorly defined viral prevalence rates. To address this, we analyzed seropositivity in US adults who ha...
Stable cell lines are critical tools of cellular assays in drug discovery and development. Over-expressing cell lines are needed to screen for hits, while functional cell lines are needed fo...
Resolving the genetics of underlying Mendelian diseases as well as host immune responses to infectious diseases is an important prerequisite for understanding their biology and for ultimate...
There has been a great deal of renewed attention in immuno-oncology over the last decade. Therapies for cancer are being developed, approved, and administered that can either initiate,...
A key aspect of translating great scientific discoveries to commercially viable cell therapies is the establishment of robust manufacturing processes that can produce the right quantity of ce...
Learning Objectives: 1. Learn why the complexity and repetitive structure of the human genome makes it impossible to detect all structural variants using short-read sequencing 2. Learn how h...
Direct recording of neural activity from the human brain (intracranial encephalography, iEEG, also known as electrocorticography, ECoG) using implanted electrodes is one of the fastest-growin...
Cannabis continues to be legalized state by state in the USA and in countries around the world. Many people are seeking solutions to either their current medication regimen that is not adequa...
The contemporary understanding of psychiatric disorders typically consists of a vast but often poorly interrelated set of facts and hypotheses that fail to coalesce into an integrated whole....
If you have ever worked in the field of gene-editing, then you must know the powerful gene-editing technology known as CRISPR. It has the potential to alter science and biotechnology at an i...
Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG Binding Protein 2 (MECP2) gene. In mouse models of RTT, deficits in long-term potentiation (LTP) at...
Speech neuroprostheses have the potential to restore communication to people living with paralysis, but naturalistic speed and expressivity are elusive. Here we use high-density surface reco...
In recent years, many countries have passed legislation regulating the use of cannabis for medical purposes. This has granted patients and clinicians access to both herbal material and cannab...
Contractile non-muscle cells, including smooth muscle and myoepithelial cells, provide the mechanical forces required for tissue homeostasis in numerous organ systems. For example, smooth mus...
The biologics development process is fraught with risks from pre-clinical studies through clinical evaluation. Prominent among these risks are changes in the critical quality attributes of th...
Introducing the new CytoScan HD Accel microarray that significantly improves the power and speed of genome-wide copy number analysis using industry-leading Chromosomal Microarray (CMA). The...
In this talk, we will discuss the nuts and bolts of the novel continuous-time neural network models: Liquid Time-Constant Networks (LTCs). Liquid neural networks are nonlinear state-space mo...
Due to the rapid emergence of the SARS-CoV-2 virus, molecular diagnostic technologies have expanded significantly. Although several diagnostic approaches were developed, real-time reverse tr...
The intrinsic activity of the brain is organized into networks and motifs that vary over time. To understand how coordinated macroscale patterns of intrinsic activity flow across the brain&r...
This presentation provides a brief introduction to biotech entrepreneurship including factors that are pertinent to biotech entrepreneurship and different myths and facts that exist. You will...
Einstein researcher Robert Singer, Ph.D., discusses a breakthrough in microscopy that is allowing scientists to track messenger RNA in living cells in real time. The study, published in the S...
The development of automated DNA sequencers using fluorescent di-deoxy nucleotide sequencing and capillary electrophoresis made it possible to generate the first draft sequences of the human...
Abstract:
•General background, diagnostic and bio-marker implications of exosomes research
•Current solutions to purifying and identifying exosomes rapidly and accurately
•R...
Wolframin is a major protein of the endoplasmic reticulum, it is expressed in most tissues and clinical data demonstrate its significant connection to diabetes mellitus. L...
Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease. While there is a scientific basis...
Activating mutations in PIK3CA are frequent in human breast cancer, and phosphoinositide 3-kinase alpha (PI3Kα) inhibitors have been approved for therapy. To characterize determinants...
INTRODUCTION: The recent coincidental emergence of the human microbiota and the Hologneomic Theory of Co-evolution unmasked the “Dual Citizenship” of symbiotic microbes and...