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The use of primary cells in vitro is compromised by the limited quantity of cells that can be isolated from one donor, a lack of or very restricted proliferation capacity (e.g. hepatocytes)...
Cellular and gene-based therapeutic approaches are the future of medicine for many conditions. As the CGT field expands and deepens, the need for consistent and reliable partners becomes cri...
Biopharmaceuticals produced with mammalian cells are the key drivers for the medication of former untreatable diseases. The development of their production processes is still challenging bec...
Dr. Kasthuri is a Neuroscience Researcher at Argonne National Labs and an Assistant Professor (adjunct) in the Dept. of Neurobiology, University of Chicago. He has an MD from Washington...
This lecture will encompass the learning experience I have had over my 14,000 RALP cases. We will present an evidence based prospective data collection and analysis of RALP outcomes. We will...
Dr. John Moore, Professor of Microbiology and Immunology at Weill Cornell Medicine, a Vaccine and Virology researcher, will talk about SARS-CoV-2 vaccines and variants and other topical issu...
In examining the potential adoption of the Oncomine Precision Assay, University of Texas Health had several criteria to consider, including the need for highly accurate detection of small sa...
CRISPR-Cas9 gene editing is a powerful technique that enables genetic modification with greater speed and accuracy than previous approaches. In this webinar, Dr. Chen highlights the advantag...
The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
The main problem for insufficient cervical cancer screening globally (less than 20% women at risk) is outreach failure. Enabling POCs with modern IT/mobile technology and connecting them with...
Targeted sequencing assays are increasingly used to identify tumor mutations that guide therapeutic decisions. Interpretation of a cancer variant’s origin and therapeutic impact poses a...
The manipulation of the genome to study disease, evaluate drug targets and to stratify patient populations is now a widely accepted concept in the field. At Horizon Discovery, genome engineer...
In the US, there are about 75 million individuals less than 18 years of age. COVID-19 has had a major impact on the pediatric population, as there have been more than 13.5 million documented...
The NIH BRAIN Initiative aims to develop new tools and neurotechnologies to transform our understanding of brain function in health and disease. That knowledge is critical to enable novel the...
This presentation provides a brief introduction to biotech entrepreneurship including factors that are pertinent to biotech entrepreneurship and different myths and facts that exist. You will...
Rapid, accurate estimation of relative ligand affinities offers the potential to allow computational methods to direct drug design and development. Towards this goal we have developed t...
The pandemic sent pharmaceutical and medical device industries scrambling to continue operations under social distancing guidelines. Businesses sent their employees to work from home, yet so...
Authors: Mark C. Benfield, Elizabeth Marchio, Aimee Thomas, Kyrsten Boswell, and Nicole Nguyen. In August 2020 the MV Bianca lost a shipping container filled with an estimated 750 million ra...
The postmortem microbiome is an emerging field in forensic science with broad application for death investigation (e.g., time since death). While the foundation for forensic microbiology beg...
To reduce the global burden diseases causes by infectious disease, including parasites and bacteria, scientists need better information about mechanisms of virulence, immune evasion, and drug...
Biobanks are a powerful resource in the advancement of precision medicine, and integrating large scale genomics data across Biobank cohorts offer opportunities to further enhance and expedite...
Stem cells, specifically induced pluripotent stem cells (iPSCs), offer exciting potential for the future of cell therapy and regenerative medicine. More recently, genetic engineering of stem ...
Disease-specific human pluripotent stem cells (hPSCs) represent a new chance to unravel cellular and molecular mechanisms of neurological diseases. Along this line, we were among the first to...
Tissues in the body are wonderfully organized, with specific arrangements of cells, extracellular matrix, secreted molecules, and fluid flow that synergize that create emergent functions. How...
Stable cell lines are critical tools of cellular assays in drug discovery and development. Over-expressing cell lines are needed to screen for hits, while functional cell lines are needed fo...
Historically the analysis and study of cannabis and cannabis-related molecules has been challenging because of their collective legal status. With the passage of the 2018 Farm Bill, at least...
Human intestinal epithelial cells (hIECs) are arranged as a monolayer of cells and provide the first line of defense against invading pathogens. Upon viral infection hIECs upregulate type I...