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The quest to decipher the complex molecular events underpinning cell polarity and organelle segregation during eukaryotic cell division presents a formidable challenge. A predominant focus o...
Human intestinal epithelial cells (hIECs) are arranged as a monolayer of cells and provide the first line of defense against invading pathogens. Upon viral infection hIECs upregulate type I...
The ongoing COVID-19 pandemic has increased awareness about sex-specific differences in immunity and outcomes following respiratory virus infections. Strong evidence of a male bias in acute...
My research program focuses on building the technology to generate diverse human cell-types for application in regenerative medicine and drug toxicology testing. While embryonic stem cells (E...
The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
Background and aim: Rapid and complex diagnosis of viral, bacterial and parasitic infections is highly desirable not only in clinical practice, but also in food safety or early warning syste...
The contemporary understanding of psychiatric disorders typically consists of a vast but often poorly interrelated set of facts and hypotheses that fail to coalesce into an integrated whole....
Direct recording of neural activity from the human brain (intracranial encephalography, iEEG, also known as electrocorticography, ECoG) using implanted electrodes is one of the fastest-growin...
Due to the rapid emergence of the SARS-CoV-2 virus, molecular diagnostic technologies have expanded significantly. Although several diagnostic approaches were developed, real-time reverse tr...
Spatial mapping of pain-associated G-Protein coupled receptors and bio-marker localization in mouse brain using RNAscope HiPlex v2 and RNA-Protein Co-Detection Assays....
Diagnosis, prognostication, and monitoring of child health relies on laboratory testing, including but not limited to key markers of thyroid, hepatic, cardiac, hematology, and renal function...
One would think that getting the diagnosis after fifteen years would end the journey. How does your work at the bench affect patients and how can you change lives through cell therapy? ...
CRISPR/Cas gene editing has become the gold standard for individual gene perturbations as well as high-throughput functional screenings, with a rapidly increasing demand for high-quality CRIS...
The BRAIN Initiative is enabling exciting advances in our understanding of human neuroscience. This session will highlight recent advances made towards understanding the human nervous system...
Learning Objectives 1. Discuss Neoantigen Mechanisms: Gain a comprehensive understanding of the mechanisms by which neoantigens are generated and recognized by the immune system, including t...
Neurotechnology promises a way to repair the damaged nervous system that requires a merger of neuroscience, engineering and clinical knowledge. Brain Computer Interfaces can now read out the...
Affinity purification, immunoprecipitation, and mass spectrometry analysis are essential tools used in proteomic studies. A successful outcome is facilitated by high-capacity supports, effici...
Mr. Getson, a USA immigration lawyer, focuses on EB-1A(Extraordinary ability) and NIW (National Interest Waiver) cases, the primary categories in which scientific researchers qualify for gree...
Circulating tumor cells (CTCs) is an emerging source used molecular cancer diagnostics. Through expression profiling of CTCs, it allows a deeper understanding about which metabolic pathways e...
To date, the therapeutic use of cannabinoids in chronic pain management remains controversial owing to the limited clinical evidence found in randomized clinical trials (RCTs), the heterogen...
The development of automated DNA sequencers using fluorescent di-deoxy nucleotide sequencing and capillary electrophoresis made it possible to generate the first draft sequences of the human...
We recently reported that HDAC6 is involved in the regulation of a number of immunosuppressive checkpoint proteins, including the Program Death Receptor Ligand 1 (PD-L1). This protein is one...
Structural variation within plant genomes has fueled domestication and selection of traits critical for modern breeding of crop plants. Nevertheless, dissecting the diversity of structural v...
Humans interact with their environment in countless ways and can switch seamlessly between activities. Even for seemingly simple tasks, a variety of sensory inputs and contextual cues are int...
The identity of somatic and pluripotent cells can be epigenetically reprogrammed and forced to adapt a new functional cell state by different methods and distinct combinations of exogenous fa...
Karyomapping, a technique for preimplantation genetic diagnosis (PGD) of single gene disorders, involves using very few or single cells, and comes with challenges due to limited amounts of s...
The quest to decipher the complex molecular events underpinning cell polarity and organelle segregation during eukaryotic cell division presents a formidable challenge. A predominant focus o...
