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    Applied Genomics

    Applied genomics is the use of genomic (or molecular medicine) to diagnose and manage disease based on PCR, DNA sequencing or other tests.

    Webinars

    • NOV 14, 2018 | 12:00 PM
      Automated Variant Classification in QIAGEN Clinical Insight Shows Near Perfect Concordance with ClinVar Expert Panel Assessments
      Automated Variant Classification in QIAGEN Clinical Insight Shows...
      As the compendium of putatively disease causing variants expands, gathering the most current and accurate information is critical to computing variant classifications. The QIAGEN knowledgebas...
      Speaker: Jennifer Poitras, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 11, 2018 | 1:30 PM
      Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in Cancer
      Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in...
      Recent work has identified epigenomic features of distal regulatory elements to be dynamic and defining indicators of cellular specification and transformation. Of particular relevance is our...
      Speaker: Martin Hirst, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 6:00 AM
      Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
      Revealing the Hidden Landscape of Structural Variants in Cancer...
      PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
      Speaker: Jonas Korlach, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 03, 2018 | 10:30 AM
      Integrating Novel Advances in Gene Delivery and Genome Engineering for Therapeutic Application
      Integrating Novel Advances in Gene Delivery and Genome Engineering...
      There have been an increasing number of successful human gene therapy clinical trials, and in particular gene delivery vehicles or vectors based on the adeno-associated virus (AAV) have enabl...
      Speaker: David Schaffer, PhD
      Presented at: CRISPR Virtual Event Series 2018
      2
      SEP 18, 2018 | 8:00 AM
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
      Speaker: Judd Hultquist, PhD
      Sponsored By: Horizon Discovery
      7
      SEP 13, 2018 | 1:30 PM
      New PacBio Solutions for High-Resolution Microbiology & Immunology Analysis
      New PacBio Solutions for High-Resolution Microbiology & Immunology...
      PacBio Sequencing has been recognized as the gold standard in microbial sequencing due to simultaneously providing long sequence reads (genome contiguity), high consensus accuracy (genome acc...
      Speaker: Jonas Korlach, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      Sponsored By: PacBio
      1
      AUG 09, 2018 | 8:00 AM
      Exon-level array: Bridging the gap between chromosomal microarray and next-gen sequencing
      Exon-level array: Bridging the gap between chromosomal microarray...
      DATE:  August 9, 2018TIME:  8:00am PDT, 11:00am EDT Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive...
      Speaker: Nicole de Leeuw, PhD , Kristina Cusmano-Ozog, MD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      9
      JUN 21, 2018 | 7:30 AM
      Keynote Presentation: Paving the Path Towards Precision Medicine in Inflammatory Bowel Diseases
      Keynote Presentation: Paving the Path Towards Precision Medicine...
      Crohn’s disease and ulcerative colitis also known as inflammatory bowel diseases or IBD, are characterized by chronic, recurrent inflammation of the gastrointestinal tract, which result...
      Speaker: Andres Hurtado-Lorenzo, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      JUN 20, 2018 | 6:00 AM
      Standardized Precision Medicine? - A Quality Management Perspective on NGS-based Individualized Therapies
      Standardized Precision Medicine? - A Quality Management Perspective...
      Precision medicine and next-generation sequencing – Two terms characterized by a highly dynamic nature, strong innovations and a bright future. Both merged together will exert a decisiv...
      Speaker: Christoph Endrullat, MS
      Presented at: Precision Medicine Virtual Event Series 2018
      2
      MAY 31, 2018 | 12:00 PM
      Cas9-Based Genome Engineering
      Cas9-Based Genome Engineering
      I will discuss three novel technologies that our laboratory has developed in recent years. In the first part of the talk, I will describe our work on engineering variants of the RNA-guided en...
      Speaker: Alejandro Chavez, MD, PhD
      Presented at: Lab Automation Virtual Event Series 2018
      2
      MAY 09, 2018 | 1:30 PM
      C.E. CREDITS
      Bimodal Gene Expression in Breast Cancer
      Bimodal Gene Expression in Breast Cancer
      Tumors are often categorized into standard molecular subtypes. However, largescale studies have demonstrated that patient heterogeneity in the regulatory make-up of tumors remain. At the tran...
      Speaker: Jessica C. Mar, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      1
      MAY 09, 2018 | 10:30 AM
      C.E. CREDITS
      Finding Coherence in Chaos by Embracing Evolution and Complexity
      Finding Coherence in Chaos by Embracing Evolution and Complexity
      Complex disease phenotypes - obesity, type II diabetes, and cancer challenge simple models in both evolution and biology.   Examination of molecular networks and their dynamic behavior o...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Genetics and Genomics Virtual Event Series 2018
      1
      APR 24, 2018 | 8:00 AM
      KASP genotyping - better by design
      KASP genotyping - better by design
      DATE: April 24, 2018TIME: 8:00AM PSTIn this talk we will cover basic principles of KASP® genotyping chemistry and designing assays that are specific to desired targets. We will go o...
      Speaker: Jonathan Curry, PhD
      Sponsored By: LGC Seracare
      13
      APR 12, 2018 | 12:00 PM
      Biomarkers to Discriminate Bacterial and Viral Infections
      Biomarkers to Discriminate Bacterial and Viral Infections
      Inappropriately prescribed antibacterials for viral respiratory illness contribute to increased healthcare costs, unnecessary drug-related adverse effects, and drive antimicrobial resistance....
      Speaker: Ephraim Tsalik, MD, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      1
      MAR 14, 2018 | 10:30 AM
      CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural Cell Mechanisms and Modeling
      CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural...
      CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis.   Even with such powerful technology at hand, sophisticated projects, su...
      Speaker: Jeremy Lehmann
      Presented at: Neuroscience Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      1
      MAR 06, 2018 | 8:00 AM
      Performance assessment of RNA sequencing and expression arrays for transcriptome analysis in cancer research
      Performance assessment of RNA sequencing and expression arrays...
      DATE: March 6, 2018TIME: 08:00am PST, 11:00am EST, 5:00pm CETRNA sequencing and expression arrays are transcriptomics techniques used to quantify transcribed genes and their isoforms. T...
      Speaker: Petr Nazarov, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      6
      JAN 30, 2018 | 9:00 AM
      WEBINAR: Metagenomics and base modifications from long, short, and linked-reads
      WEBINAR: Metagenomics and base modifications from long, short,...
      DATE: January 30, 2018TIME: 9:00AM PST, 12:00PM ESTInfectious disease surveillance and monitoring is critical in settings where disease outbreaks and antibiotic resistance can dramatica...
      Speaker: Christopher Mason, PhD , Shuiquan Tang, PhD
      Sponsored By: Zymo Research
      6 1
      JAN 18, 2018 | 8:00 AM
      Unravel the exome odyssey: overcome the challenges of exon-level CNV detection
      Unravel the exome odyssey: overcome the challenges of exon-level...
      Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive calls and are challenging...
      Speaker: Alka Chaubey, PhD, FACMG , Kristina Cusmano-Ozog, MD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      8
      DEC 06, 2017 | 8:00 AM
      WEBINAR:  #5: A Complete Workflow for Human Cell Line Authentication
      WEBINAR: #5: A Complete Workflow for Human Cell Line Authentication
      DATE: November 16, 2017TIME: 7:00am PST, 10:00 am EST, 3:00pm CETThis is the fifth topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’Th...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      5 2
      NOV 16, 2017 | 7:00 AM
      WEBINAR:  #4: Genome editing workflow facilitated by the Thermo Fisher Scientific portfolio solution
      WEBINAR: #4: Genome editing workflow facilitated by the Thermo...
      DATE: November 07, 2017TIME: 7:00am PST, 10:00 am EST, 3:00pm CETThis is the fourth topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’G...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      5
      NOV 15, 2017 | 9:00 AM
      WEBINAR: The essential role of miRNA and mRNA on cancer progression and biomarker discovery
      WEBINAR: The essential role of miRNA and mRNA on cancer progression...
      DATE: November 15, 2017TIME: 09:00am PST, 12:00pm ESTMicroRNAs (miRNA) are a class of small non-coding RNAs (approximately 21 nt long) that bind complementary sequences in target mRNAs...
      Speaker: Dr. Malte Buchholz
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      6
      NOV 14, 2017 | 9:00 AM
      WEBINAR: CRISPRa tools for transcriptional activation studies
      WEBINAR: CRISPRa tools for transcriptional activation studies
      DATE: November 14, 2017TIME: 09:00am PST, 12:00pm ESTThe CRISPR-Cas9 system has been adapted to upregulate any gene in its endogenous context, enabling overexpression experiments and av...
      Speaker: Žaklina Strezoska , Benedict Cross
      Sponsored By: Dharmacon, a Horizon Discovery Group Company
      11 4
      NOV 07, 2017 | 8:00 AM
      WEBINAR: The power of multiplexing and applications of the QuantiGene Plex Assay in oncology research and diagnostics
      WEBINAR: The power of multiplexing and applications of the QuantiGene...
      Cancer research diagnostic services in pathology laboratories worldwide have been negatively impacted by a lack of fresh-frozen tissue samples, the degradation of DNA and RNA in archival tiss...
      Speaker: Godfrey Grech, PhD
      Presented at: Protein and Cell Analysis Education Series
      Sponsored By: Thermo Fisher Scientific
      2 1
      OCT 25, 2017 | 8:00 AM
      WEBINAR: Genotyping to enable large-scale precision medicine research studies
      WEBINAR: Genotyping to enable large-scale precision medicine research...
      DATE: October 25, 2017TIME: 08:00am PDT, 11:00am EDTAs we learn more about the implications of genetic variation in 21st century medicine, the utilization of genotyping as a molecular t...
      Speaker: Mark Bouzyk, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      5 1
    NOV 14, 2018 | 12:00 PM
    Automated Variant Classification in QIAGEN Clinical Insight Shows Near Perfect Concordance with ClinVar Expert Panel Assessments
    Automated Variant Classification in QIAGEN Clinical Insight Shows...
    As the compendium of putatively disease causing variants expands, gathering the most current and accurate information is critical to computing variant classifications. The QIAGEN knowledgebas...
    Speaker: Jennifer Poitras, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 11, 2018 | 1:30 PM
    Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in Cancer
    Exploiting Cis-Regulatory Enhancers as Therapeutic Targets in...
    Recent work has identified epigenomic features of distal regulatory elements to be dynamic and defining indicators of cellular specification and transformation. Of particular relevance is our...
    Speaker: Martin Hirst, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 6:00 AM
    Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
    Revealing the Hidden Landscape of Structural Variants in Cancer...
    PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
    Speaker: Jonas Korlach, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 03, 2018 | 10:30 AM
    Integrating Novel Advances in Gene Delivery and Genome Engineering for Therapeutic Application
    Integrating Novel Advances in Gene Delivery and Genome Engineering...
    There have been an increasing number of successful human gene therapy clinical trials, and in particular gene delivery vehicles or vectors based on the adeno-associated virus (AAV) have enabl...
    Speaker: David Schaffer, PhD
    Presented at: CRISPR Virtual Event Series 2018
    2
    SEP 18, 2018 | 8:00 AM
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
    Speaker: Judd Hultquist, PhD
    Sponsored By: Horizon Discovery
    7
     
     
  • SEP 13, 2018 | 1:30 PM
    New PacBio Solutions for High-Resolution Microbiology & Immunology Analysis
    New PacBio Solutions for High-Resolution Microbiology & Immunology...
    PacBio Sequencing has been recognized as the gold standard in microbial sequencing due to simultaneously providing long sequence reads (genome contiguity), high consensus accuracy (genome acc...
    Speaker: Jonas Korlach, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    Sponsored By: PacBio
    1
    AUG 09, 2018 | 8:00 AM
    Exon-level array: Bridging the gap between chromosomal microarray and next-gen sequencing
    Exon-level array: Bridging the gap between chromosomal microarray...
    DATE:  August 9, 2018TIME:  8:00am PDT, 11:00am EDT Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive...
    Speaker: Nicole de Leeuw, PhD , Kristina Cusmano-Ozog, MD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    9
    JUN 21, 2018 | 7:30 AM
    Keynote Presentation: Paving the Path Towards Precision Medicine in Inflammatory Bowel Diseases
    Keynote Presentation: Paving the Path Towards Precision Medicine...
    Crohn’s disease and ulcerative colitis also known as inflammatory bowel diseases or IBD, are characterized by chronic, recurrent inflammation of the gastrointestinal tract, which result...
    Speaker: Andres Hurtado-Lorenzo, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
    JUN 20, 2018 | 6:00 AM
    Standardized Precision Medicine? - A Quality Management Perspective on NGS-based Individualized Therapies
    Standardized Precision Medicine? - A Quality Management Perspective...
    Precision medicine and next-generation sequencing – Two terms characterized by a highly dynamic nature, strong innovations and a bright future. Both merged together will exert a decisiv...
    Speaker: Christoph Endrullat, MS
    Presented at: Precision Medicine Virtual Event Series 2018
    2
    MAY 31, 2018 | 12:00 PM
    Cas9-Based Genome Engineering
    Cas9-Based Genome Engineering
    I will discuss three novel technologies that our laboratory has developed in recent years. In the first part of the talk, I will describe our work on engineering variants of the RNA-guided en...
    Speaker: Alejandro Chavez, MD, PhD
    Presented at: Lab Automation Virtual Event Series 2018
    2
     
     
  • MAY 09, 2018 | 1:30 PM
    C.E. CREDITS
    Bimodal Gene Expression in Breast Cancer
    Bimodal Gene Expression in Breast Cancer
    Tumors are often categorized into standard molecular subtypes. However, largescale studies have demonstrated that patient heterogeneity in the regulatory make-up of tumors remain. At the tran...
    Speaker: Jessica C. Mar, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    1
    MAY 09, 2018 | 10:30 AM
    C.E. CREDITS
    Finding Coherence in Chaos by Embracing Evolution and Complexity
    Finding Coherence in Chaos by Embracing Evolution and Complexity
    Complex disease phenotypes - obesity, type II diabetes, and cancer challenge simple models in both evolution and biology.   Examination of molecular networks and their dynamic behavior o...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Genetics and Genomics Virtual Event Series 2018
    1
    APR 24, 2018 | 8:00 AM
    KASP genotyping - better by design
    KASP genotyping - better by design
    DATE: April 24, 2018TIME: 8:00AM PSTIn this talk we will cover basic principles of KASP® genotyping chemistry and designing assays that are specific to desired targets. We will go o...
    Speaker: Jonathan Curry, PhD
    Sponsored By: LGC Seracare
    13
    APR 12, 2018 | 12:00 PM
    Biomarkers to Discriminate Bacterial and Viral Infections
    Biomarkers to Discriminate Bacterial and Viral Infections
    Inappropriately prescribed antibacterials for viral respiratory illness contribute to increased healthcare costs, unnecessary drug-related adverse effects, and drive antimicrobial resistance....
    Speaker: Ephraim Tsalik, MD, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    1
    MAR 14, 2018 | 10:30 AM
    CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural Cell Mechanisms and Modeling
    CRISPR and ZFN Mediated Gene Editing for the Exploration of Neural...
    CRISPR Cas9 nucleases have revolutionized gene editing enabling unprecedented efficiency of targeted mutagenesis.   Even with such powerful technology at hand, sophisticated projects, su...
    Speaker: Jeremy Lehmann
    Presented at: Neuroscience Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    1
     
     
  • MAR 06, 2018 | 8:00 AM
    Performance assessment of RNA sequencing and expression arrays for transcriptome analysis in cancer research
    Performance assessment of RNA sequencing and expression arrays...
    DATE: March 6, 2018TIME: 08:00am PST, 11:00am EST, 5:00pm CETRNA sequencing and expression arrays are transcriptomics techniques used to quantify transcribed genes and their isoforms. T...
    Speaker: Petr Nazarov, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    6
    JAN 30, 2018 | 9:00 AM
    WEBINAR: Metagenomics and base modifications from long, short, and linked-reads
    WEBINAR: Metagenomics and base modifications from long, short,...
    DATE: January 30, 2018TIME: 9:00AM PST, 12:00PM ESTInfectious disease surveillance and monitoring is critical in settings where disease outbreaks and antibiotic resistance can dramatica...
    Speaker: Christopher Mason, PhD , Shuiquan Tang, PhD
    Sponsored By: Zymo Research
    6 1
    JAN 18, 2018 | 8:00 AM
    Unravel the exome odyssey: overcome the challenges of exon-level CNV detection
    Unravel the exome odyssey: overcome the challenges of exon-level...
    Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive calls and are challenging...
    Speaker: Alka Chaubey, PhD, FACMG , Kristina Cusmano-Ozog, MD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    8
    DEC 06, 2017 | 8:00 AM
    WEBINAR:  #5: A Complete Workflow for Human Cell Line Authentication
    WEBINAR: #5: A Complete Workflow for Human Cell Line Authentication
    DATE: November 16, 2017TIME: 7:00am PST, 10:00 am EST, 3:00pm CETThis is the fifth topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’Th...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    5 2
    NOV 16, 2017 | 7:00 AM
    WEBINAR:  #4: Genome editing workflow facilitated by the Thermo Fisher Scientific portfolio solution
    WEBINAR: #4: Genome editing workflow facilitated by the Thermo...
    DATE: November 07, 2017TIME: 7:00am PST, 10:00 am EST, 3:00pm CETThis is the fourth topic in the webinar series on ‘Sanger Sequencing & Fragment Analysis made easy’G...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    5
     
     
  • NOV 15, 2017 | 9:00 AM
    WEBINAR: The essential role of miRNA and mRNA on cancer progression and biomarker discovery
    WEBINAR: The essential role of miRNA and mRNA on cancer progression...
    DATE: November 15, 2017TIME: 09:00am PST, 12:00pm ESTMicroRNAs (miRNA) are a class of small non-coding RNAs (approximately 21 nt long) that bind complementary sequences in target mRNAs...
    Speaker: Dr. Malte Buchholz
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    6
    NOV 14, 2017 | 9:00 AM
    WEBINAR: CRISPRa tools for transcriptional activation studies
    WEBINAR: CRISPRa tools for transcriptional activation studies
    DATE: November 14, 2017TIME: 09:00am PST, 12:00pm ESTThe CRISPR-Cas9 system has been adapted to upregulate any gene in its endogenous context, enabling overexpression experiments and av...
    Speaker: Žaklina Strezoska , Benedict Cross
    Sponsored By: Dharmacon, a Horizon Discovery Group Company
    11 4
    NOV 07, 2017 | 8:00 AM
    WEBINAR: The power of multiplexing and applications of the QuantiGene Plex Assay in oncology research and diagnostics
    WEBINAR: The power of multiplexing and applications of the QuantiGene...
    Cancer research diagnostic services in pathology laboratories worldwide have been negatively impacted by a lack of fresh-frozen tissue samples, the degradation of DNA and RNA in archival tiss...
    Speaker: Godfrey Grech, PhD
    Presented at: Protein and Cell Analysis Education Series
    Sponsored By: Thermo Fisher Scientific
    2 1
    OCT 25, 2017 | 8:00 AM
    WEBINAR: Genotyping to enable large-scale precision medicine research studies
    WEBINAR: Genotyping to enable large-scale precision medicine research...
    DATE: October 25, 2017TIME: 08:00am PDT, 11:00am EDTAs we learn more about the implications of genetic variation in 21st century medicine, the utilization of genotyping as a molecular t...
    Speaker: Mark Bouzyk, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
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