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    Beta Cells

    Beta Cells are responsible for insulin secretion and control of plasma glucose levels. Within the pancreas, the beta cells are located in areas called the islets of Langerhans where they constitute the predominant type of cell.

    Webinars

    • JUN 03, 2020 | 9:30 AM
      Keynote Presentation: The Importance of Tissue Chemistry in Immunity-Oncology
      Keynote Presentation: The Importance of Tissue Chemistry in Immunity-Oncology
      Cancer cells can acquire immune resistance resulting in a loss of immunosurveillance. Tumor cells can upregulate PDL-1 which binds to PD-1. This complex inhibits CD8 Tumor Infiltrating cells...
      Speaker: Thomas M. Grogan, MD
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: Roche Diagnostics
      1
      JUN 03, 2020 | 6:00 AM
      Keynote Presentation: Development of Rational Immunotherapy Combinations to Overcome the Immunosuppressive Prostate Tumor Microenvironment
      Keynote Presentation: Development of Rational Immunotherapy Combinations...
      Immune checkpoint therapies targeting the CTLA-4 and PD-(L)1 pathways have been largely clinically disappointing for patients with prostate cancer. This can be attributed to the highly immun...
      Speaker: Sumit K. Subudhi, MD, PhD
      Presented at: Immuno-Oncology Virtual Event Series 2020
      1
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      APR 23, 2020 | 10:30 AM
      Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
      Keynote Presentation: Systematic identification of therapeutic...
      Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
      Speaker: Kris C. Wood, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      APR 14, 2020 | 9:00 AM
      Gibco Cell Culture Heroes: Work From Home Edition
      Gibco Cell Culture Heroes: Work From Home Edition
      DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
      Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      12 1
      MAR 27, 2020 | 9:00 AM
      Modified Dental Composite for Bone Repair
      Modified Dental Composite for Bone Repair
      DATE: March 27, 2020 TIME: 9:00am PDT, 12:00pm EDT Osteoporosis causes a decrease in bone density, along with deterioration of the bone’s microarchitecture at a faster rate than normal...
      Speaker: Mayda Arshad
      Sponsored By: Thermo Fisher Scientific/Gibco
      11
      MAR 11, 2020 | 10:30 AM
      Innate immunity in chronic neurodegeneration
      Innate immunity in chronic neurodegeneration
      The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
      Speaker: Michael Heneka, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      Sponsored By: NanoString Technologies
      1
      JAN 30, 2020 | 9:00 AM
      An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening
      An Automated Cancer Organoid Culture Platform to Accelerate Research...
      DATE: January 30, 2020 TIME: 9:00am PST, 12:00pm EST Recent advances in in vitro 3D cellular culture technologies, such as organoids, rapidly developed and established novel, more physiologi...
      Speaker: Brooke Schuster
      Sponsored By: Thermo Fisher Scientific/Gibco
      10
      DEC 17, 2019 | 9:00 AM
      The role of SIRT1/LXR signaling in diabetic retinopathy
      The role of SIRT1/LXR signaling in diabetic retinopathy
      DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
      Speaker: Sandra Hammer, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      NOV 19, 2019 | 10:00 AM
      LC3-associated endocytosis: guarding against neuroinflammation & neurodegeneration
      LC3-associated endocytosis: guarding against neuroinflammation...
      DATE: November 19, 2019TIME: 10:00am PSTMicroglial cells are the resident innate immune cells of the central nervous system (CNS) and are responsible for regulating inflammatory activati...
      Speaker: Bradlee L. Heckmann, Ph.D.
      Sponsored By: Miltenyi Biotec
      6
      SEP 10, 2019 | 8:00 AM
      Next Generation Sequencing of the Immune System: From Single Cell to Bulk RNA
      Next Generation Sequencing of the Immune System: From Single Cell...
      DATE: September 10, 2019TIME: 8:00am PTNext generation sequencing of the immune repertoire allows detailed, sequence-specific insight into the immune system’s adaptive response...
      Speaker: Miranda Byrne-Steele, Ph.D.
      Sponsored By: Beckman Coulter Life Sciences
      8 1
      MAY 23, 2019 | 9:00 AM
      Doing More with Less: Stem Cells Regulate Their Fate by Altering Their Stiffness
      Doing More with Less: Stem Cells Regulate Their Fate by Altering...
      DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
      Speaker: Melika Sarem, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      APR 23, 2019 | 11:00 AM
      Utilizing the lens epithelial explant culture system to investigate cataract formation
      Utilizing the lens epithelial explant culture system to investigate...
      DATE: April 23, 2019TIME: 11:00am PDT, 2:00pm EDT Cataract, a clouding of the ocular lens, is the leading cause of blindness worldwide. Currently the only means of treatment i...
      Speaker: Daisy Shu, B.Optom, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      MAR 28, 2019 | 12:00 PM
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      The Intersection of Nutrition, Microbiome and Medical Cannabis
      Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
      Speaker: Debra Kimless, MD
      Presented at: Cannabis Sciences Virtual Event Series 2019
      6
      FEB 27, 2019 | 12:00 PM
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
      Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
      Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
      Speaker: Sarah Warren, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      Sponsored By: NanoString Technologies
      1
      NOV 01, 2018 | 12:00 AM
      Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
      Glycosylation and stabilization of programmed death ligand-1 suppresses...
      The success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on cancer cell and immune cell interaction, how cancer cells i...
      Speaker: Chia-Wei Li, PhD
      Presented at: Dimension of Time: From Culture to Assay
      1
      OCT 23, 2018 | 7:00 AM
      FLIPR 1536-well application in high throughput screening
      FLIPR 1536-well application in high throughput screening
      DATE: October 23, 2018TIME: 7:00AM PDTHigh Throughput Screening for the European Lead Factory (ELF) has been performed at Pivot Park Screening Centre (PPSC). 72 HTS campaigns have...
      Speaker: Helma Van Den Hurk, PhD , Tsang Wai Lam, BSc
      Sponsored By: Molecular Devices
      4
      OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 6:00 AM
      Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
      Precise Detection of T-Cell Receptors Using RNAseq With Unique...
      Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 01, 2018 | 12:00 AM
      Efficient generation of pancreatic β cell precursors from human pluripotent stem cells
      Efficient generation of pancreatic β cell precursors from human...
      Pancreatic β cell replacement therapy is considered as a potential strategy to treat diabetes. To date, transplantation of pancreatic islets from cadavers is the most effective approach...
      Speaker: Essam Abdelalim
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      4
      SEP 13, 2018 | 1:30 PM
      Mechanisms of Antimicrobial Bioconversion by Environmental and Host-Associated Bacteria
      Mechanisms of Antimicrobial Bioconversion by Environmental and...
      The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. Resistance genes are widely distributed in the soil and may act as a reservoir for pathogen antibioti...
      Speaker: Terence Crofts, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      3
      SEP 12, 2018 | 8:00 AM
      Advancing precision immunotherapy through next generation sequencing of T-cell receptors: Part II
      Advancing precision immunotherapy through next generation sequencing...
      DATE:  September 12, 2018 TIME:  08:00am PDT, 11:00am EDT In the last presentation of this webinar series, we will continue our discussions on recent advancements i...
      Speaker: Timothy Looney, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      9
      AUG 16, 2018 | 8:00 AM
      Advancing precision immunotherapy through next-generation sequencing of T cell receptors: Part I
      Advancing precision immunotherapy through next-generation sequencing...
      DATE: August, 16, 2018TIME: 08:00AM PDTThis webinar will review recent advancements in the application of next-generation sequencing of T cell receptor beta (TCRB) chain repertoires towards...
      Speaker: Timothy Looney, PhD
      Sponsored By: Thermo Fisher Scientific - Ion Torrent
      7
      JUL 19, 2018 | 9:00 AM
      Investigating the role of microRNAs in pancreatic cancer progression
      Investigating the role of microRNAs in pancreatic cancer progression
      DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
      Speaker: Silvia Ottaviani, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      9 5
    JUN 03, 2020 | 9:30 AM
    Keynote Presentation: The Importance of Tissue Chemistry in Immunity-Oncology
    Keynote Presentation: The Importance of Tissue Chemistry in Immunity-Oncology
    Cancer cells can acquire immune resistance resulting in a loss of immunosurveillance. Tumor cells can upregulate PDL-1 which binds to PD-1. This complex inhibits CD8 Tumor Infiltrating cells...
    Speaker: Thomas M. Grogan, MD
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: Roche Diagnostics
    1
    JUN 03, 2020 | 6:00 AM
    Keynote Presentation: Development of Rational Immunotherapy Combinations to Overcome the Immunosuppressive Prostate Tumor Microenvironment
    Keynote Presentation: Development of Rational Immunotherapy Combinations...
    Immune checkpoint therapies targeting the CTLA-4 and PD-(L)1 pathways have been largely clinically disappointing for patients with prostate cancer. This can be attributed to the highly immun...
    Speaker: Sumit K. Subudhi, MD, PhD
    Presented at: Immuno-Oncology Virtual Event Series 2020
    1
    MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
    APR 23, 2020 | 10:30 AM
    Keynote Presentation: Systematic identification of therapeutic strategies that leverage tumor evolution
    Keynote Presentation: Systematic identification of therapeutic...
    Our laboratory uses tools from pharmacology, genomics, and cell signaling to identify new precision anticancer therapeutic strategies. Under this broad heading, our work involves three key a...
    Speaker: Kris C. Wood, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
    APR 14, 2020 | 9:00 AM
    Gibco Cell Culture Heroes: Work From Home Edition
    Gibco Cell Culture Heroes: Work From Home Edition
    DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
    Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    12 1
     
     
  • MAR 27, 2020 | 9:00 AM
    Modified Dental Composite for Bone Repair
    Modified Dental Composite for Bone Repair
    DATE: March 27, 2020 TIME: 9:00am PDT, 12:00pm EDT Osteoporosis causes a decrease in bone density, along with deterioration of the bone’s microarchitecture at a faster rate than normal...
    Speaker: Mayda Arshad
    Sponsored By: Thermo Fisher Scientific/Gibco
    11
    MAR 11, 2020 | 10:30 AM
    Innate immunity in chronic neurodegeneration
    Innate immunity in chronic neurodegeneration
    The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
    Speaker: Michael Heneka, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    Sponsored By: NanoString Technologies
    1
    JAN 30, 2020 | 9:00 AM
    An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening
    An Automated Cancer Organoid Culture Platform to Accelerate Research...
    DATE: January 30, 2020 TIME: 9:00am PST, 12:00pm EST Recent advances in in vitro 3D cellular culture technologies, such as organoids, rapidly developed and established novel, more physiologi...
    Speaker: Brooke Schuster
    Sponsored By: Thermo Fisher Scientific/Gibco
    10
    DEC 17, 2019 | 9:00 AM
    The role of SIRT1/LXR signaling in diabetic retinopathy
    The role of SIRT1/LXR signaling in diabetic retinopathy
    DATE: December 17, 2019TIME: 9:00am PST, 12:00pm EST Purpose: Liver x receptors (LXRs) are hypothesized to serve as a link between lipid metabolism and inflammation by prom...
    Speaker: Sandra Hammer, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    NOV 19, 2019 | 10:00 AM
    LC3-associated endocytosis: guarding against neuroinflammation & neurodegeneration
    LC3-associated endocytosis: guarding against neuroinflammation...
    DATE: November 19, 2019TIME: 10:00am PSTMicroglial cells are the resident innate immune cells of the central nervous system (CNS) and are responsible for regulating inflammatory activati...
    Speaker: Bradlee L. Heckmann, Ph.D.
    Sponsored By: Miltenyi Biotec
    6
     
     
  • SEP 10, 2019 | 8:00 AM
    Next Generation Sequencing of the Immune System: From Single Cell to Bulk RNA
    Next Generation Sequencing of the Immune System: From Single Cell...
    DATE: September 10, 2019TIME: 8:00am PTNext generation sequencing of the immune repertoire allows detailed, sequence-specific insight into the immune system’s adaptive response...
    Speaker: Miranda Byrne-Steele, Ph.D.
    Sponsored By: Beckman Coulter Life Sciences
    8 1
    MAY 23, 2019 | 9:00 AM
    Doing More with Less: Stem Cells Regulate Their Fate by Altering Their Stiffness
    Doing More with Less: Stem Cells Regulate Their Fate by Altering...
    DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
    Speaker: Melika Sarem, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
    APR 23, 2019 | 11:00 AM
    Utilizing the lens epithelial explant culture system to investigate cataract formation
    Utilizing the lens epithelial explant culture system to investigate...
    DATE: April 23, 2019TIME: 11:00am PDT, 2:00pm EDT Cataract, a clouding of the ocular lens, is the leading cause of blindness worldwide. Currently the only means of treatment i...
    Speaker: Daisy Shu, B.Optom, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
    MAR 28, 2019 | 12:00 PM
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    The Intersection of Nutrition, Microbiome and Medical Cannabis
    Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
    Speaker: Debra Kimless, MD
    Presented at: Cannabis Sciences Virtual Event Series 2019
    6
    FEB 27, 2019 | 12:00 PM
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint Blockade in Melanoma
    Evaluating Biomarkers for Response to Neoadjuvant Immune Checkpoint...
    Surgery is the first line of treatment for Stage III melanoma. Often adjuvant therapy is administered post-surgery, which can include weeks of radiation, chemotherapy, targeted drug therapy,...
    Speaker: Sarah Warren, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    Sponsored By: NanoString Technologies
    1
     
     
  • NOV 01, 2018 | 12:00 AM
    Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
    Glycosylation and stabilization of programmed death ligand-1 suppresses...
    The success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on cancer cell and immune cell interaction, how cancer cells i...
    Speaker: Chia-Wei Li, PhD
    Presented at: Dimension of Time: From Culture to Assay
    1
    OCT 23, 2018 | 7:00 AM
    FLIPR 1536-well application in high throughput screening
    FLIPR 1536-well application in high throughput screening
    DATE: October 23, 2018TIME: 7:00AM PDTHigh Throughput Screening for the European Lead Factory (ELF) has been performed at Pivot Park Screening Centre (PPSC). 72 HTS campaigns have...
    Speaker: Helma Van Den Hurk, PhD , Tsang Wai Lam, BSc
    Sponsored By: Molecular Devices
    4
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 6:00 AM
    Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
    Precise Detection of T-Cell Receptors Using RNAseq With Unique...
    Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 01, 2018 | 12:00 AM
    Efficient generation of pancreatic β cell precursors from human pluripotent stem cells
    Efficient generation of pancreatic β cell precursors from human...
    Pancreatic β cell replacement therapy is considered as a potential strategy to treat diabetes. To date, transplantation of pancreatic islets from cadavers is the most effective approach...
    Speaker: Essam Abdelalim
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    4
     
     
  • SEP 13, 2018 | 1:30 PM
    Mechanisms of Antimicrobial Bioconversion by Environmental and Host-Associated Bacteria
    Mechanisms of Antimicrobial Bioconversion by Environmental and...
    The soil microbiome can produce, resist, or degrade antibiotics and even catabolize them. Resistance genes are widely distributed in the soil and may act as a reservoir for pathogen antibioti...
    Speaker: Terence Crofts, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    3
    SEP 12, 2018 | 8:00 AM
    Advancing precision immunotherapy through next generation sequencing of T-cell receptors: Part II
    Advancing precision immunotherapy through next generation sequencing...
    DATE:  September 12, 2018 TIME:  08:00am PDT, 11:00am EDT In the last presentation of this webinar series, we will continue our discussions on recent advancements i...
    Speaker: Timothy Looney, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    9
    AUG 16, 2018 | 8:00 AM
    Advancing precision immunotherapy through next-generation sequencing of T cell receptors: Part I
    Advancing precision immunotherapy through next-generation sequencing...
    DATE: August, 16, 2018TIME: 08:00AM PDTThis webinar will review recent advancements in the application of next-generation sequencing of T cell receptor beta (TCRB) chain repertoires towards...
    Speaker: Timothy Looney, PhD
    Sponsored By: Thermo Fisher Scientific - Ion Torrent
    7
    JUL 19, 2018 | 9:00 AM
    Investigating the role of microRNAs in pancreatic cancer progression
    Investigating the role of microRNAs in pancreatic cancer progression
    DATE:  July 19, 2018TIME:  09:00am PDT Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5 year-survival rate of approximately 6%. Despite recent...
    Speaker: Silvia Ottaviani, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
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