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    Biomarker Discovery

    Biomarker Discovery is a process in which molecular substances in the body are used to indicate health or disease. One of the biggest challenges in biomarker discovery is the difficulty of identifying medium to low abundance proteins in complex biological samples.

    Webinars

    • FEB 22, 2017 | 10:30 AM
      Beyond the hype: the evidence behind the role of genetics in drug response
      Beyond the hype: the evidence behind the role of genetics in drug...
      Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease.  While there is a scientific basis...
      Speaker: Matt Nelson, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      5
      FEB 22, 2017 | 9:00 AM
      The Microbiome-Gut-Brain Axis: Linking Gastrointestinal and Neurobehavioral Processes in Autism Spectrum Disorder
      The Microbiome-Gut-Brain Axis: Linking Gastrointestinal and Neurobehavioral...
      Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
      Speaker: Ruth Luna, PhD, MB (ASCP) CM
      Presented at: Precision Medicine Virtual Event Series 2017
      6
      FEB 22, 2017 | 7:30 AM
      KEYNOTE: Where innovation and regulation meet
      KEYNOTE: Where innovation and regulation meet
      Launched in early 2015, the Precision Medicine Initiative (PMI) takes advantage of the progress made in genomic testing – progress largely driven by rapid advances in DNA sequencing tec...
      Speaker: Laura Koontz, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      2
      FEB 22, 2017 | 6:00 AM
      GenomeFIRST â„¢ A new paradigm for the return of genomic results
      GenomeFIRST â„¢ A new paradigm for the return of genomic results
      The starting point for an interaction between a patient and a clinician is almost always a set of clinical facts (aka a phenotype). Phenotype-first medicine is the standard way in which the p...
      Speaker: Marc Williams, MD
      Presented at: Precision Medicine Virtual Event Series 2017
      4
      FEB 22, 2017 | 6:00 AM
      Mate-pair next generation sequencing as a powerful clinical tool for the characterization of cancer
      Mate-pair next generation sequencing as a powerful clinical tool...
      Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
      Speaker: David Smith, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      4
      JAN 17, 2017 | 8:00 AM
      Benefits and limitations of primary and secondary antibody conjugates
      Benefits and limitations of primary and secondary antibody conjugates
      Join Dr Javier Conde Vancells as he reviews the use of primary and secondary antibody conjugates across multiple lab applications, including a review of direct vs. indirect methods in cellula...
      Speaker: Javier Vancells, PhD
      Presented at: Abcam virtual exhibition: support and products to advance your research
      4
      NOV 16, 2016 | 8:00 AM
      The important role of lncRNAs in breast cancer
      The important role of lncRNAs in breast cancer
      DATE:  November 16, 2016 TIME:  8:00am PT, 11:00am ET  Breast cancer is the most commonly diagnosed cancer in women and is the second leading cause of cancer death among wo...
      Speaker: Rebecca DeVaux, PhD , Alfredo Hidalgo-Miranda, PhD
      Sponsored By: Affymetrix, Affymetrix
      8
      NOV 04, 2016 | 10:00 AM
      Applying a multi-omics approach to tumor biomarker discovery - case studies
      Applying a multi-omics approach to tumor biomarker discovery -...
      DATE:  November 4, 2016 TIME:  10:00am PT, 1:00pm ET How do you develop clinically relevant biomarkers? Systematic tumor profiling with multi-omics tools and rapid analytical...
      Speaker: Antonia Sepulveda, MD, PhD , Yang Yang, PhD , Tamara Lotan, MD
      Sponsored By: Affymetrix, Affymetrix
      10 1
      NOV 03, 2016 | 10:30 AM
      Found in Translation: ST2 From Discovery to Clinical Adoption
      Found in Translation: ST2 From Discovery to Clinical Adoption
      Laboratory tests come into existence through a variety of processes but regardless of the genesis all share a certain set of requirements. These include discovery, development, validation, re...
      Speaker: James Snider, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
      NOV 03, 2016 | 6:00 AM
      Mutation Detection Simplified: From Liquid Biopsy in clinical oncology to the detection of Drug Resistance Associated Mutations in virology
      Mutation Detection Simplified: From Liquid Biopsy in clinical...
      Sanger sequencing and polymerase chain reaction (PCR) methods have been the standard molecular methods in clinical diagnostics for decades.  Next-Generation Sequencing (NGS) technology r...
      Speaker: Gerd Michel, PhD , Lou Welebob
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      5
      NOV 02, 2016 | 1:30 PM
      A Platform to Digitize Biology: A Potential Pathway to Exponential Medicine
      A Platform to Digitize Biology: A Potential Pathway to Exponential...
      Today there are about 7B mobile phone worldwide and about 50,000 mobile health applications actively changing the landscape of how healthcare will be delivered in the next years. While numero...
      Speaker: John McDevitt, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      4
      OCT 11, 2016 | 8:00 AM
      Pro-Enkephalin: A Novel New Biomarker for Assessment of Kidney Function, Early Prediction and Identification of Acute Kidney Injury
      Pro-Enkephalin: A Novel New Biomarker for Assessment of Kidney...
      DATE:  October 11, 2016 TIME:  8:00am PT, 11:00 ET Chronic Renal Dysfunction (CKD) and Acute Kidney Injury (AKI) are increasing in prevalence today and can be escalated due to d...
      Speaker: Alan Maisel, M.D.
      Sponsored By: Sphingotec LLC, Sphingotec LLC
      24 1
      OCT 11, 2016 | 7:00 AM
      Two Dimensional Liquid Chromatography Applied to the Characterization of Monoclonal Antibodies and Antibody-Drug Conjugates
      Two Dimensional Liquid Chromatography Applied to the Characterization...
      DATE:  October 11, 2016 TIME:  7:00am PT, 10:00am ET Monoclonal antibodies (mAbs) have emerged as important therapeutics for the treatment of life-threatening diseases. The succ...
      Speaker: Koen Sandra, PhD
      Sponsored By: Agilent Genomics, Agilent Genomics
      5
      OCT 06, 2016 | 7:30 AM
      Keynote Speaker: Reference Component Analysis of Single Cell Transcriptomes Reveals Cellular Heterogeneity in Colorectal Cancer
      Keynote Speaker: Reference Component Analysis of Single Cell Transcriptomes...
      Intra-tumor heterogeneity is a major obstacle to cancer treatment. Existing single-cell studies of intra-tumor heterogeneity have largely focused on DNA mutations; functional heterogeneity is...
      Speaker: Shyam Prabhakar, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      2
      OCT 05, 2016 | 6:00 AM
      Melanoma - View from the Frontlines of Immunotherapy and Precision Medicine
      Melanoma - View from the Frontlines of Immunotherapy and Precision...
      Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
      Speaker: Louise Perkins, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
      2
      SEP 29, 2016 | 10:00 AM
      Advancing Personalized Medicine through whole-genome profiling
      Advancing Personalized Medicine through whole-genome profiling
      DATE:  September 29, 2016 TIME:  10:00am PT, 1:00pm ET One of the challenges with personalized medicine lies in the identification of robust, clinically relevant biomarkers. Tra...
      Speaker: Stewart Neill, MD
      Sponsored By: Affymetrix, Affymetrix
      10
      SEP 08, 2016 | 12:00 PM
      Plant Viruses: Everywhere and Often Mutualistic
      Plant Viruses: Everywhere and Often Mutualistic
       Virus Ecology is a field that is gaining momentum, fueled in part by metagenomic studies from many environments previously ignored. Biodiversity studies of plant viruses show that they...
      Speaker: Marilyn Roossinck, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2016
      4
      SEP 08, 2016 | 7:30 AM
      Gene Expression Profiling During Infection NanoString® nCounter accurately quantifies pathogen and host transcripts from tiny amount of infection tissue
      Gene Expression Profiling During Infection NanoString® nCounter...
      Our speaker, Wenjie Xu, Ph.D., will present his publication data demonstrating how nCounter® technology can advance your infectious disease research faster and more accurately with unprec...
      Speaker: Wenjie Xu, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2016
      2
      AUG 11, 2016 | 11:00 AM
      RNA-ISH for Long non-coding RNAs - new game changers in pathology
      RNA-ISH for Long non-coding RNAs - new game changers in pathology
      DATE: August 11, 2016 TIME: 11:00AM PST, 2:00PM ET, 7:00PM GMT The central dogma that forms the backbone of molecular biology is that DNA codes for RNA (transcription) which then c...
      Speaker: Rohit Mehra, M.D.
      Sponsored By: Advanced Cell Diagnostics, Advanced Cell Diagnostics
      12
      JUN 30, 2016 | 7:30 AM
      Proteome centric precision medicine:  embracing pathological diversity
      Proteome centric precision medicine: embracing pathological diversity
      Precision medicine requires success in two intertwined aspects: precision therapy and personalized medicine. Precision therapy is being able to effectively treat the right disease; to have th...
      Speaker: Jennifer Van Eyk, PhD
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      8
      JUN 15, 2016 | 7:30 AM
      Glycomics and glycoproteomics by CESI-MS for biomarker discovery and biopharmaceutical characterization
      Glycomics and glycoproteomics by CESI-MS for biomarker discovery...
      Glycosylation is one of the most prevalent co- and post-translational modifications of human proteins and is known to affect the protein properties. Glycosylation is known to be involved in m...
      Speaker: Guinevere Kammeijer, MSc
      Sponsored By: Sciex, Sciex
      11 2
      MAY 12, 2016 | 7:30 AM
      Polymorphic miRNA binding sites in the WFS1 gene are risk factors of diabetes mellitus
      Polymorphic miRNA binding sites in the WFS1 gene are risk factors...
           Wolframin is a major protein of the endoplasmic reticulum, it is expressed in most tissues and clinical data demonstrate its significant connection to diabetes mellitus. L...
      Speaker: Zsolt Rónai, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2016
      5
      MAY 04, 2016 | 9:00 AM
      Cell free methods for producing protein microarrays
      Cell free methods for producing protein microarrays
      Self-assembling protein microarrays arrays can be used to study protein-protein interactions, protein-drug interactions, search for enzyme substrates, and as tools to search for disease bioma...
      Speaker: Joshua LaBaer, MD, PhD
      Presented at: 2016 Gibco ExpressionWorld
      2
      APR 11, 2016 | 9:00 AM
      WEBINAR: The epigenome in normal human placental development and its dysregulation in preeclampsia
      WEBINAR: The epigenome in normal human placental development and...
      9:00 AM PT, 11:00 AM CT, 12:00 PM ET Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...
      Speaker: Peter Jones, Ph.D., D.Sc. , Nandor Than, MD, PhD
      Sponsored By: Zymo Research, Zymo Research
      10 4
    FEB 22, 2017 | 10:30 AM
    Beyond the hype: the evidence behind the role of genetics in drug response
    Beyond the hype: the evidence behind the role of genetics in drug...
    Much has been made in the popular press about importance of our "genes" in everything from our weight, intelligence, and our risk of disease.  While there is a scientific basis...
    Speaker: Matt Nelson, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    5
    FEB 22, 2017 | 9:00 AM
    The Microbiome-Gut-Brain Axis: Linking Gastrointestinal and Neurobehavioral Processes in Autism Spectrum Disorder
    The Microbiome-Gut-Brain Axis: Linking Gastrointestinal and Neurobehavioral...
    Gastrointestinal (GI) disorders are now widely recognized as a clinical symptom of autism spectrum disorder (ASD), and research into the microbiome-gut-brain axis is beginning to reveal the i...
    Speaker: Ruth Luna, PhD, MB (ASCP) CM
    Presented at: Precision Medicine Virtual Event Series 2017
    6
    FEB 22, 2017 | 7:30 AM
    KEYNOTE: Where innovation and regulation meet
    KEYNOTE: Where innovation and regulation meet
    Launched in early 2015, the Precision Medicine Initiative (PMI) takes advantage of the progress made in genomic testing – progress largely driven by rapid advances in DNA sequencing tec...
    Speaker: Laura Koontz, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    2
    FEB 22, 2017 | 6:00 AM
    GenomeFIRST â„¢ A new paradigm for the return of genomic results
    GenomeFIRST â„¢ A new paradigm for the return of genomic results
    The starting point for an interaction between a patient and a clinician is almost always a set of clinical facts (aka a phenotype). Phenotype-first medicine is the standard way in which the p...
    Speaker: Marc Williams, MD
    Presented at: Precision Medicine Virtual Event Series 2017
    4
    FEB 22, 2017 | 6:00 AM
    Mate-pair next generation sequencing as a powerful clinical tool for the characterization of cancer
    Mate-pair next generation sequencing as a powerful clinical tool...
    Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
    Speaker: David Smith, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    4
     
     
  • JAN 17, 2017 | 8:00 AM
    Benefits and limitations of primary and secondary antibody conjugates
    Benefits and limitations of primary and secondary antibody conjugates
    Join Dr Javier Conde Vancells as he reviews the use of primary and secondary antibody conjugates across multiple lab applications, including a review of direct vs. indirect methods in cellula...
    Speaker: Javier Vancells, PhD
    Presented at: Abcam virtual exhibition: support and products to advance your research
    4
    NOV 16, 2016 | 8:00 AM
    The important role of lncRNAs in breast cancer
    The important role of lncRNAs in breast cancer
    DATE:  November 16, 2016 TIME:  8:00am PT, 11:00am ET  Breast cancer is the most commonly diagnosed cancer in women and is the second leading cause of cancer death among wo...
    Speaker: Rebecca DeVaux, PhD , Alfredo Hidalgo-Miranda, PhD
    Sponsored By: Affymetrix, Affymetrix
    8
    NOV 04, 2016 | 10:00 AM
    Applying a multi-omics approach to tumor biomarker discovery - case studies
    Applying a multi-omics approach to tumor biomarker discovery -...
    DATE:  November 4, 2016 TIME:  10:00am PT, 1:00pm ET How do you develop clinically relevant biomarkers? Systematic tumor profiling with multi-omics tools and rapid analytical...
    Speaker: Antonia Sepulveda, MD, PhD , Yang Yang, PhD , Tamara Lotan, MD
    Sponsored By: Affymetrix, Affymetrix
    10 1
    NOV 03, 2016 | 10:30 AM
    Found in Translation: ST2 From Discovery to Clinical Adoption
    Found in Translation: ST2 From Discovery to Clinical Adoption
    Laboratory tests come into existence through a variety of processes but regardless of the genesis all share a certain set of requirements. These include discovery, development, validation, re...
    Speaker: James Snider, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
    NOV 03, 2016 | 6:00 AM
    Mutation Detection Simplified: From Liquid Biopsy in clinical oncology to the detection of Drug Resistance Associated Mutations in virology
    Mutation Detection Simplified: From Liquid Biopsy in clinical...
    Sanger sequencing and polymerase chain reaction (PCR) methods have been the standard molecular methods in clinical diagnostics for decades.  Next-Generation Sequencing (NGS) technology r...
    Speaker: Gerd Michel, PhD , Lou Welebob
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    5
     
     
  • NOV 02, 2016 | 1:30 PM
    A Platform to Digitize Biology: A Potential Pathway to Exponential Medicine
    A Platform to Digitize Biology: A Potential Pathway to Exponential...
    Today there are about 7B mobile phone worldwide and about 50,000 mobile health applications actively changing the landscape of how healthcare will be delivered in the next years. While numero...
    Speaker: John McDevitt, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    4
    OCT 11, 2016 | 8:00 AM
    Pro-Enkephalin: A Novel New Biomarker for Assessment of Kidney Function, Early Prediction and Identification of Acute Kidney Injury
    Pro-Enkephalin: A Novel New Biomarker for Assessment of Kidney...
    DATE:  October 11, 2016 TIME:  8:00am PT, 11:00 ET Chronic Renal Dysfunction (CKD) and Acute Kidney Injury (AKI) are increasing in prevalence today and can be escalated due to d...
    Speaker: Alan Maisel, M.D.
    Sponsored By: Sphingotec LLC, Sphingotec LLC
    24 1
    OCT 11, 2016 | 7:00 AM
    Two Dimensional Liquid Chromatography Applied to the Characterization of Monoclonal Antibodies and Antibody-Drug Conjugates
    Two Dimensional Liquid Chromatography Applied to the Characterization...
    DATE:  October 11, 2016 TIME:  7:00am PT, 10:00am ET Monoclonal antibodies (mAbs) have emerged as important therapeutics for the treatment of life-threatening diseases. The succ...
    Speaker: Koen Sandra, PhD
    Sponsored By: Agilent Genomics, Agilent Genomics
    5
    OCT 06, 2016 | 7:30 AM
    Keynote Speaker: Reference Component Analysis of Single Cell Transcriptomes Reveals Cellular Heterogeneity in Colorectal Cancer
    Keynote Speaker: Reference Component Analysis of Single Cell Transcriptomes...
    Intra-tumor heterogeneity is a major obstacle to cancer treatment. Existing single-cell studies of intra-tumor heterogeneity have largely focused on DNA mutations; functional heterogeneity is...
    Speaker: Shyam Prabhakar, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    2
    OCT 05, 2016 | 6:00 AM
    Melanoma - View from the Frontlines of Immunotherapy and Precision Medicine
    Melanoma - View from the Frontlines of Immunotherapy and Precision...
    Melanoma arises in the pigment producing cells (melanocytes) and is the deadliest of the skin cancers. It accounts for nearly 200,000 new cases of cancer each year worldwide and in the U.S. o...
    Speaker: Louise Perkins, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2016
    2
     
     
  • SEP 29, 2016 | 10:00 AM
    Advancing Personalized Medicine through whole-genome profiling
    Advancing Personalized Medicine through whole-genome profiling
    DATE:  September 29, 2016 TIME:  10:00am PT, 1:00pm ET One of the challenges with personalized medicine lies in the identification of robust, clinically relevant biomarkers. Tra...
    Speaker: Stewart Neill, MD
    Sponsored By: Affymetrix, Affymetrix
    10
    SEP 08, 2016 | 12:00 PM
    Plant Viruses: Everywhere and Often Mutualistic
    Plant Viruses: Everywhere and Often Mutualistic
     Virus Ecology is a field that is gaining momentum, fueled in part by metagenomic studies from many environments previously ignored. Biodiversity studies of plant viruses show that they...
    Speaker: Marilyn Roossinck, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2016
    4
    SEP 08, 2016 | 7:30 AM
    Gene Expression Profiling During Infection NanoString® nCounter accurately quantifies pathogen and host transcripts from tiny amount of infection tissue
    Gene Expression Profiling During Infection NanoString® nCounter...
    Our speaker, Wenjie Xu, Ph.D., will present his publication data demonstrating how nCounter® technology can advance your infectious disease research faster and more accurately with unprec...
    Speaker: Wenjie Xu, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2016
    2
    AUG 11, 2016 | 11:00 AM
    RNA-ISH for Long non-coding RNAs - new game changers in pathology
    RNA-ISH for Long non-coding RNAs - new game changers in pathology
    DATE: August 11, 2016 TIME: 11:00AM PST, 2:00PM ET, 7:00PM GMT The central dogma that forms the backbone of molecular biology is that DNA codes for RNA (transcription) which then c...
    Speaker: Rohit Mehra, M.D.
    Sponsored By: Advanced Cell Diagnostics, Advanced Cell Diagnostics
    12
    JUN 30, 2016 | 7:30 AM
    Proteome centric precision medicine:  embracing pathological diversity
    Proteome centric precision medicine: embracing pathological diversity
    Precision medicine requires success in two intertwined aspects: precision therapy and personalized medicine. Precision therapy is being able to effectively treat the right disease; to have th...
    Speaker: Jennifer Van Eyk, PhD
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    8
     
     
  • JUN 15, 2016 | 7:30 AM
    Glycomics and glycoproteomics by CESI-MS for biomarker discovery and biopharmaceutical characterization
    Glycomics and glycoproteomics by CESI-MS for biomarker discovery...
    Glycosylation is one of the most prevalent co- and post-translational modifications of human proteins and is known to affect the protein properties. Glycosylation is known to be involved in m...
    Speaker: Guinevere Kammeijer, MSc
    Sponsored By: Sciex, Sciex
    11 2
    MAY 12, 2016 | 7:30 AM
    Polymorphic miRNA binding sites in the WFS1 gene are risk factors of diabetes mellitus
    Polymorphic miRNA binding sites in the WFS1 gene are risk factors...
         Wolframin is a major protein of the endoplasmic reticulum, it is expressed in most tissues and clinical data demonstrate its significant connection to diabetes mellitus. L...
    Speaker: Zsolt Rónai, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2016
    5
    MAY 04, 2016 | 9:00 AM
    Cell free methods for producing protein microarrays
    Cell free methods for producing protein microarrays
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    Speaker: Joshua LaBaer, MD, PhD
    Presented at: 2016 Gibco ExpressionWorld
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    WEBINAR: The epigenome in normal human placental development and its dysregulation in preeclampsia
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    Speaker: Peter Jones, Ph.D., D.Sc. , Nandor Than, MD, PhD
    Sponsored By: Zymo Research, Zymo Research
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