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    Biotherapeutics

    Biotherapeutics: Biotherapeutic products derived from recombinant DNA technology such as interferons, interleukins, and growth factors have provided a major advance in the safety and effectiveness of therapeutic peptides and proteins, and they have a successful record in treating many life-threatening and chronic diseases. Since contamination with unwanted pathogens can be greatly reduced and production volumes are expanded by the developed biotechnology, many more patients have increased access to biotherapeutic products. Technical issues such as the potential immunogenicity of active substances produced under differing manufacturing conditions must also be considered.

    Webinars

    • NOV 13, 2020 | 10:00 AM
      Immune profiling of hospitalized COVID-19 patients
      Immune profiling of hospitalized COVID-19 patients
      Date: November 13, 2020 10:00am PST, 1:00pm EST Coronavirus disease 2019 (COVID-19) is currently a global pandemic, but human immune responses to the virus remain poorly understood....
      Speaker: Josephine Giles Ph.D.
      Sponsored By: Beckman Coulter Life Sciences
      15
      NOV 12, 2020 | 10:00 AM
      FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
      FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
      Date: November 12, 2020 Time: 10:00am (PST), 1:00pm (EST) Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate anti...
      Speaker: Tilman Schlothauer, Ph.D
      Sponsored By: Roche CustomBiotech
      3
      NOV 12, 2020 | 9:00 AM
      Back to Work, School, and Life: Utility of COVID-19 Testing to Help Communities Restore Normality
      Back to Work, School, and Life: Utility of COVID-19 Testing to...
      Testing volumes need to increase by orders of magnitude in order to restore communities back to normality. This workshop focuses on solutions that equip laboratories to participate in expand...
      Speaker: Dr. Jared R. Auclair , Frank Ong, MD, CPI, CCRP
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: Thermo Fisher Scientific
      5
      OCT 21, 2020 | 12:00 AM
      Developing a Complete Workflow Including N-Linked Glycans Analysis for Monoclonal Antibodies with High Resolution Mass Spectrometry and Fluorescence Detection
      Developing a Complete Workflow Including N-Linked Glycans Analysis...
      Accurate characterization of monoclonal antibodies is essential to development of biotherapeutics. Thorough understanding of biotherapeutic properties aids in the optimization of bioprocess...
      Speaker: Brian Domanski
      Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
      1
      OCT 01, 2020 | 10:00 AM
      Improvements to Bile Collection Studies in Rats
      Improvements to Bile Collection Studies in Rats
      Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
      Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
      Sponsored By: SAI Infusion Technologies
      5 3
      SEP 22, 2020 | 10:30 AM
      Agilent LC-MS Released Glycan Workflow
      Agilent LC-MS Released Glycan Workflow
      The structure of N-linked glycans can play a critical role in the pharmacology of therapeutic proteins, potentially affecting immunogenicity, pharmacokinetics and pharmacodynamics. This make...
      Speaker: Christopher Colangelo, PhD, MBA
      Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
      1
      SEP 10, 2020 | 9:00 AM
      An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
      An Insider's Look: How One Parameter Can Optimize Key Phases of...
      Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
      Speaker: Tara Barreira , Kristeena Wright
      Sponsored By: Advanced Instruments
      7
      SEP 04, 2020 | 8:00 AM
      Incorporation and Automation of RNAscope Technology into your COVID-19 Viral Pathogenesis Research
      Incorporation and Automation of RNAscope Technology into your...
      Date: September 4, 2020 Time: 8:00am (PTD), 11:00am (ETD) Direct detection of viral RNA in human or other animal cells by RNA in situ hybridization (ISH) is a powerful tool to establish the...
      Speaker: Jyoti Phatak-Sheldon , Andrea De Biase, M.S. , Damian Cockfield
      Sponsored By: Leica Biosystems, ACD - A Bio-Techne Brand
      14 8
      SEP 03, 2020 | 9:00 AM
      The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
      The Complexities of SV Analytical Ultracentrifugation: AAVs are...
      DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
      Speaker: Dr. Lake Paul
      Sponsored By: Beckman Coulter Life Sciences
      12
      AUG 25, 2020 | 8:00 AM
      How LV and AAV Transfection Platforms will Shape the Future of Gene Therapy Manufacturing
      How LV and AAV Transfection Platforms will Shape the Future of...
      DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
      Speaker: Leisha Kopp
      Sponsored By: Mirus
      18 2
      AUG 11, 2020 | 10:00 AM
      Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
      Better resolution for CE-SDS analysis of new biopharmaceutical...
      DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
      Speaker: Andras Guttman, PhD
      Sponsored By: SCIEX
      9 4
      JUL 22, 2020 | 10:00 AM
      Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
      Molecular Diagnostic Solutions in a Pandemic: Planning for the...
      DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
      Speaker: Heba Mostafa, MD, PhD, D(ABMM)
      Sponsored By: GenMark Dx
      27 13
      JUN 18, 2020 | 9:00 AM
      The Next Generation of Ion Mobility MS with Structures for Lossless Ion Manipulations
      The Next Generation of Ion Mobility MS with Structures for Lossless...
      Structures for Lossless Ion Manipulations (SLIM) is a technology that provides a means to trap and transmit ions with high efficiency over very long path lengths (up to multiple kilometers)...
      Speaker: Christian Klein, PhD , Daniel DeBord, PhD
      Presented at: Agilent's Virtual Mass Spectacular!
      2
      JUN 17, 2020 | 3:00 PM
      Accelerating vaccine development using a next generation microfluidic CE platform
      Accelerating vaccine development using a next generation microfluidic...
      When producing a quality vaccine, all manufacturers must confirm the purity as well as the stability of their formulation and final product. Sample quantity and measurement time are often th...
      Speaker: Jeray Thelwell
      Presented at: Coronavirus Series
      Sponsored By: PerkinElmer
      1
      JUN 02, 2020 | 9:00 AM
      Osmolality Testing: Providing Unique Process Control for Downstream Operations
      Osmolality Testing: Providing Unique Process Control for Downstream...
      DATE: June 2, 2020 TIME: 9:00am PT, 12:00pm ET Osmolality is a well-established parameter for upstream bioprocessing, formulation, analytical development and QC applications throughout the m...
      Speaker: Alois Jungbauer, PhD , Kristeena Wright, PhD
      Sponsored By: Advanced Instruments
      11 1
      APR 16, 2020 | 9:00 AM
      Visualize more biomarkers and extract more insights: Moving from single marker IHC to multiplex IF
      Visualize more biomarkers and extract more insights: Moving from...
      DATE: April 16, 2020 TIME: 9:00am PT, 12:00pm ET There is an increasing need to evaluate and understand unique phenotypes and mechanisms of action within the tumor microenvironment. Existing...
      Speaker: Scott Lawrence (M.S., HT(ASCP)) [C] , Katir Patel, PhD
      Sponsored By: Ultivue
      5
      APR 08, 2020 | 9:00 AM
      Case Study: From Ligand discovery to developing a purification platform and delivering GMP-ready affinity chromatography columns
      Case Study: From Ligand discovery to developing a purification...
      This presentation is about a client-focused approach used to find an all synthetic ligand which is developed into an affinity adsorbent – followed by working with the client to develop...
      Speaker: Buzz Lobbezoo
      Presented at: BioProcessing Virtual Event Series 2020
      1
      APR 08, 2020 | 12:00 AM
      The NISTmAb and Related Biopharmaceutical Resources
      The NISTmAb and Related Biopharmaceutical Resources
      The NIST Biomanufacturing Program develops measurement science, standards, reference data and tools to support the development, manufacturing, and regulatory approval of biologic medicines....
      Speaker: John Schiel, PhD
      Presented at: BioProcessing Virtual Event Series 2020
      1
      APR 07, 2020 | 8:00 AM
      Best Practice Criteria for Pluripotent Stem Cell Lines
      Best Practice Criteria for Pluripotent Stem Cell Lines
      DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
      Speaker: Lyn Healy
      Sponsored By: STEMCELL Technologies
      22
      DEC 10, 2019 | 7:00 AM
      Proven Answers for Protein, Vaccine and Gene Therapy Analysis
      Proven Answers for Protein, Vaccine and Gene Therapy Analysis
      DATE: December 11, 2019 TIME: 7:00am PST, 10:00am EST Rapid growth in the cell and gene therapy industry has generated an urgent need for robust analytics around characterization of both vec...
      Speaker: Mukesh Malik, PhD
      Sponsored By: SCIEX
      8 1
      OCT 24, 2019 | 1:30 PM
      Characterization of Biotherapeutics by Chemometric and Machine Learning Analysis of NMR Spectra
      Characterization of Biotherapeutics by Chemometric and Machine...
      With annual sales exceeding $145 billion, growth of biologic therapeutics is outpacing that of small-molecule drugs, and the development, manufacture, and delivery of biologics presents very...
      Speaker: Frank Delaglio, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      4 1
      OCT 24, 2019 | 9:00 AM
      A Comparison of Established NMR Chemometric Methods in Biopharma
      A Comparison of Established NMR Chemometric Methods in Biopharma
      Therapeutic monoclonal antibodies are a clinically important and life-saving class of biotherapeutics used in the treatment of several previously intractable diseases. However, their developm...
      Speaker: K. Wade Elliott, PhD
      Presented at: Analytical Chemistry Virtual Event Series 2019
      3
      OCT 22, 2019 | 9:00 AM
      Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality as a Process Parameter
      Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality...
      DATE: October 22, 2019 TIME: 9:00am PDT, 12:00PM EDT...
      Speaker: Angela Bazigos , Kristeena Wright, PhD , Shweta Nair
      Sponsored By: Advanced Instruments
      10 1
      SEP 17, 2019 | 6:00 AM
      Post-translational modification enrichment and quantitation for precision medicine and drug development
      Post-translational modification enrichment and quantitation for...
      DATE: September 17, 2019TIME: 6:00 am PDT, 9:00am EDT, 2:00pm BST, 3:00pm CEST Abstract: Learning Objectives: one two Webina...
      Speaker: Connie Jimenez, PhD , Manuel Tzouros, PhD
      Sponsored By: Cell Signaling Technology
      8 2
    NOV 13, 2020 | 10:00 AM
    Immune profiling of hospitalized COVID-19 patients
    Immune profiling of hospitalized COVID-19 patients
    Date: November 13, 2020 10:00am PST, 1:00pm EST Coronavirus disease 2019 (COVID-19) is currently a global pandemic, but human immune responses to the virus remain poorly understood....
    Speaker: Josephine Giles Ph.D.
    Sponsored By: Beckman Coulter Life Sciences
    15
    NOV 12, 2020 | 10:00 AM
    FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
    FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
    Date: November 12, 2020 Time: 10:00am (PST), 1:00pm (EST) Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate anti...
    Speaker: Tilman Schlothauer, Ph.D
    Sponsored By: Roche CustomBiotech
    3
    NOV 12, 2020 | 9:00 AM
    Back to Work, School, and Life: Utility of COVID-19 Testing to Help Communities Restore Normality
    Back to Work, School, and Life: Utility of COVID-19 Testing to...
    Testing volumes need to increase by orders of magnitude in order to restore communities back to normality. This workshop focuses on solutions that equip laboratories to participate in expand...
    Speaker: Dr. Jared R. Auclair , Frank Ong, MD, CPI, CCRP
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: Thermo Fisher Scientific
    5
    OCT 21, 2020 | 12:00 AM
    Developing a Complete Workflow Including N-Linked Glycans Analysis for Monoclonal Antibodies with High Resolution Mass Spectrometry and Fluorescence Detection
    Developing a Complete Workflow Including N-Linked Glycans Analysis...
    Accurate characterization of monoclonal antibodies is essential to development of biotherapeutics. Thorough understanding of biotherapeutic properties aids in the optimization of bioprocess...
    Speaker: Brian Domanski
    Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
    1
    OCT 01, 2020 | 10:00 AM
    Improvements to Bile Collection Studies in Rats
    Improvements to Bile Collection Studies in Rats
    Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
    Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
    Sponsored By: SAI Infusion Technologies
    5 3
     
     
  • SEP 22, 2020 | 10:30 AM
    Agilent LC-MS Released Glycan Workflow
    Agilent LC-MS Released Glycan Workflow
    The structure of N-linked glycans can play a critical role in the pharmacology of therapeutic proteins, potentially affecting immunogenicity, pharmacokinetics and pharmacodynamics. This make...
    Speaker: Christopher Colangelo, PhD, MBA
    Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
    1
    SEP 10, 2020 | 9:00 AM
    An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
    An Insider's Look: How One Parameter Can Optimize Key Phases of...
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    Speaker: Tara Barreira , Kristeena Wright
    Sponsored By: Advanced Instruments
    7
    SEP 04, 2020 | 8:00 AM
    Incorporation and Automation of RNAscope Technology into your COVID-19 Viral Pathogenesis Research
    Incorporation and Automation of RNAscope Technology into your...
    Date: September 4, 2020 Time: 8:00am (PTD), 11:00am (ETD) Direct detection of viral RNA in human or other animal cells by RNA in situ hybridization (ISH) is a powerful tool to establish the...
    Speaker: Jyoti Phatak-Sheldon , Andrea De Biase, M.S. , Damian Cockfield
    Sponsored By: Leica Biosystems, ACD - A Bio-Techne Brand
    14 8
    SEP 03, 2020 | 9:00 AM
    The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
    The Complexities of SV Analytical Ultracentrifugation: AAVs are...
    DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
    Speaker: Dr. Lake Paul
    Sponsored By: Beckman Coulter Life Sciences
    12
    AUG 25, 2020 | 8:00 AM
    How LV and AAV Transfection Platforms will Shape the Future of Gene Therapy Manufacturing
    How LV and AAV Transfection Platforms will Shape the Future of...
    DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
    Speaker: Leisha Kopp
    Sponsored By: Mirus
    18 2
     
     
  • AUG 11, 2020 | 10:00 AM
    Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
    Better resolution for CE-SDS analysis of new biopharmaceutical...
    DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
    Speaker: Andras Guttman, PhD
    Sponsored By: SCIEX
    9 4
    JUL 22, 2020 | 10:00 AM
    Molecular Diagnostic Solutions in a Pandemic: Planning for the 2020/2021 Flu Season with the Implementation of the ePlex® Respiratory Pathogen Panel 2
    Molecular Diagnostic Solutions in a Pandemic: Planning for the...
    DATE: July 23, 2020 TIME: 10:00 am PDT The SARS-CoV-2 pandemic has taken a toll on many sectors of the medical community. As the pandemic took a grip on the laboratory, the need for diagnost...
    Speaker: Heba Mostafa, MD, PhD, D(ABMM)
    Sponsored By: GenMark Dx
    27 13
    JUN 18, 2020 | 9:00 AM
    The Next Generation of Ion Mobility MS with Structures for Lossless Ion Manipulations
    The Next Generation of Ion Mobility MS with Structures for Lossless...
    Structures for Lossless Ion Manipulations (SLIM) is a technology that provides a means to trap and transmit ions with high efficiency over very long path lengths (up to multiple kilometers)...
    Speaker: Christian Klein, PhD , Daniel DeBord, PhD
    Presented at: Agilent's Virtual Mass Spectacular!
    2
    JUN 17, 2020 | 3:00 PM
    Accelerating vaccine development using a next generation microfluidic CE platform
    Accelerating vaccine development using a next generation microfluidic...
    When producing a quality vaccine, all manufacturers must confirm the purity as well as the stability of their formulation and final product. Sample quantity and measurement time are often th...
    Speaker: Jeray Thelwell
    Presented at: Coronavirus Series
    Sponsored By: PerkinElmer
    1
    JUN 02, 2020 | 9:00 AM
    Osmolality Testing: Providing Unique Process Control for Downstream Operations
    Osmolality Testing: Providing Unique Process Control for Downstream...
    DATE: June 2, 2020 TIME: 9:00am PT, 12:00pm ET Osmolality is a well-established parameter for upstream bioprocessing, formulation, analytical development and QC applications throughout the m...
    Speaker: Alois Jungbauer, PhD , Kristeena Wright, PhD
    Sponsored By: Advanced Instruments
    11 1
     
     
  • APR 16, 2020 | 9:00 AM
    Visualize more biomarkers and extract more insights: Moving from single marker IHC to multiplex IF
    Visualize more biomarkers and extract more insights: Moving from...
    DATE: April 16, 2020 TIME: 9:00am PT, 12:00pm ET There is an increasing need to evaluate and understand unique phenotypes and mechanisms of action within the tumor microenvironment. Existing...
    Speaker: Scott Lawrence (M.S., HT(ASCP)) [C] , Katir Patel, PhD
    Sponsored By: Ultivue
    5
    APR 08, 2020 | 9:00 AM
    Case Study: From Ligand discovery to developing a purification platform and delivering GMP-ready affinity chromatography columns
    Case Study: From Ligand discovery to developing a purification...
    This presentation is about a client-focused approach used to find an all synthetic ligand which is developed into an affinity adsorbent – followed by working with the client to develop...
    Speaker: Buzz Lobbezoo
    Presented at: BioProcessing Virtual Event Series 2020
    1
    APR 08, 2020 | 12:00 AM
    The NISTmAb and Related Biopharmaceutical Resources
    The NISTmAb and Related Biopharmaceutical Resources
    The NIST Biomanufacturing Program develops measurement science, standards, reference data and tools to support the development, manufacturing, and regulatory approval of biologic medicines....
    Speaker: John Schiel, PhD
    Presented at: BioProcessing Virtual Event Series 2020
    1
    APR 07, 2020 | 8:00 AM
    Best Practice Criteria for Pluripotent Stem Cell Lines
    Best Practice Criteria for Pluripotent Stem Cell Lines
    DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
    Speaker: Lyn Healy
    Sponsored By: STEMCELL Technologies
    22
    DEC 10, 2019 | 7:00 AM
    Proven Answers for Protein, Vaccine and Gene Therapy Analysis
    Proven Answers for Protein, Vaccine and Gene Therapy Analysis
    DATE: December 11, 2019 TIME: 7:00am PST, 10:00am EST Rapid growth in the cell and gene therapy industry has generated an urgent need for robust analytics around characterization of both vec...
    Speaker: Mukesh Malik, PhD
    Sponsored By: SCIEX
    8 1
     
     
  • OCT 24, 2019 | 1:30 PM
    Characterization of Biotherapeutics by Chemometric and Machine Learning Analysis of NMR Spectra
    Characterization of Biotherapeutics by Chemometric and Machine...
    With annual sales exceeding $145 billion, growth of biologic therapeutics is outpacing that of small-molecule drugs, and the development, manufacture, and delivery of biologics presents very...
    Speaker: Frank Delaglio, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    4 1
    OCT 24, 2019 | 9:00 AM
    A Comparison of Established NMR Chemometric Methods in Biopharma
    A Comparison of Established NMR Chemometric Methods in Biopharma
    Therapeutic monoclonal antibodies are a clinically important and life-saving class of biotherapeutics used in the treatment of several previously intractable diseases. However, their developm...
    Speaker: K. Wade Elliott, PhD
    Presented at: Analytical Chemistry Virtual Event Series 2019
    3
    OCT 22, 2019 | 9:00 AM
    Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality as a Process Parameter
    Preserving Data Integrity: 21 CFR Part 11 Compliance and Osmolality...
    DATE: October 22, 2019 TIME: 9:00am PDT, 12:00PM EDT...
    Speaker: Angela Bazigos , Kristeena Wright, PhD , Shweta Nair
    Sponsored By: Advanced Instruments
    10 1
    SEP 17, 2019 | 6:00 AM
    Post-translational modification enrichment and quantitation for precision medicine and drug development
    Post-translational modification enrichment and quantitation for...
    DATE: September 17, 2019TIME: 6:00 am PDT, 9:00am EDT, 2:00pm BST, 3:00pm CEST Abstract: Learning Objectives: one two Webina...
    Speaker: Connie Jimenez, PhD , Manuel Tzouros, PhD
    Sponsored By: Cell Signaling Technology
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