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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
MAR 22, 2023 | 9:00 AM
We have developed 3D-shaped hydrogel microparticle platforms to capture cells, as well as isolate and label their secretions. These “lab on a particle” systems enable sorting cel...
FEB 22, 2023 | 12:00 PM
Have you ever tried to access the genomic profiles of cell lines before using them in your preclinical experiments just to come up empty-handed? Maybe you’ve scoured public databases f...
FEB 22, 2023 | 5:30 AM
Many current technologies used in drug discovery and preclinical development programmes typically involve multi-step operations, extensive hands-on time, and lengthy liquid handling processe...
FEB 15, 2023 | 7:00 AM
Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
NOV 17, 2022 | 7:00 AM
Date: November 17, 2022 Time: 7:00am (PST), 10:00am (EST), 4:00pm (CET) In order to truly understand cell biology, researchers need easy-to-use tools that preserve the natural complexity of...
NOV 16, 2022 | 10:00 AM
Date: November 16, 2022 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) Eli Lilly, a global healthcare leader, has implemented a next generation research (NGR) initiative to improve the valu...
NOV 16, 2022 | 9:00 AM
Date: November 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) No more estimating. No more ranges. No more uncertainty. While PDX tumor models are crucial for gaining predictive ins...
NOV 08, 2022 | 8:00 AM
Date: November 08, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CEST) While flow cytometry shines by its flexibility, it requires a high level of expertise in antibody panel development,...
NOV 01, 2022 | 10:00 AM
Date: November 01, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 6:00pm (CET) Our laboratory developed the Pig-a gene mutation assay as a means to simply and reliably evaluate the potential mutage...
OCT 19, 2022 | 6:45 AM
SARS-CoV-2 vaccine efficacy testing is now facing increasing challenges in the face of an ongoing pandemic with the emergence of new variants and waning vaccine immunity. Evidence supports t...
OCT 12, 2022 | 8:30 PM
Date: October 12, 2022, October 13, 2022 Time: 8:30pm (PDT), 11:30pm (EDT), 5:30am (CEST) High dimensional full spectrum flow cytometry holds the promise of addressing long-held questions in...
OCT 04, 2022 | 7:00 AM
Date: October 04, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) The ability to derive induced pluripotent stem cells (iPSCs) from differentiated cell types such as fibroblasts, has r...
SEP 14, 2022 | 8:00 AM
Date: September 14, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) In this session, the benefits of combining in-line high speed imaging with flow cytometry will be explored. Acoustic...
AUG 16, 2022 | 9:00 AM
Date: August 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Combining our rich experience in molecular biology and cell system engineering, GenScript has established the TurboCHO&...
JUL 26, 2022 | 9:00 AM
Date: July 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Organoids and spheroids are increasingly being used in many research applications, including drug discovery, toxicology,...
JUN 29, 2022 | 10:00 PM
Date: June 30, 2022 Time: 3:00pm (AEST), 1:00pm (SGT), 2:00pm (JP/KR) Analyzing sea water is never an easy task. With high total dissolved solids (TDS), seawater is considered one of the mos...
JUN 28, 2022 | 9:00 PM
Date: June 29, 2022 Time: 12:00pm (PST), 2:00pm (EST), 8:00pm (CEST) The burden of antimicrobial resistance (AMR) has been acknowledged worldwide by leading health institutes. Besides the ne...
JUN 22, 2022 | 8:00 AM
Biopharmaceutical discovery, development and manufacturing requires the use of genetic analysis across the development continuum. Sanger sequencing and fragment analysis by capillary electro...
JUN 16, 2022 | 8:00 AM
Date: June 16, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Many researchers combine electrophysiological recordings with imaging applications, where a light source with high light...
JUN 01, 2022 | 9:00 AM
Date: June 01, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The manufacturing process for cell and gene therapies is complex and can contain process-related impurities from multiple...
MAY 26, 2022 | 9:00 AM
Date: May 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) In early drug development, lead clone selection requires large number of clones screening in cell line development. Develo...
MAY 25, 2022 | 10:00 AM
Date: May 25, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Programmable RNA base editors are excellent tools to modify RNA transcripts at precise locations or designated hotspots. P...
MAY 24, 2022 | 9:00 AM
Date: May 24, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Recent breakthroughs in autologous cellular therapies have generated tremendous excitement for the industry; however, thes...
FEB 22, 2023 | 5:30 AM
Many current technologies used in drug discovery and preclinical development programmes typically involve multi-step operations, extensive hands-on time, and lengthy liquid handling processe...
FEB 15, 2023 | 7:00 AM
Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
NOV 17, 2022 | 7:00 AM
Date: November 17, 2022 Time: 7:00am (PST), 10:00am (EST), 4:00pm (CET) In order to truly understand cell biology, researchers need easy-to-use tools that preserve the natural complexity of...
NOV 16, 2022 | 10:00 AM
Date: November 16, 2022 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) Eli Lilly, a global healthcare leader, has implemented a next generation research (NGR) initiative to improve the valu...
NOV 16, 2022 | 9:00 AM
Date: November 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) No more estimating. No more ranges. No more uncertainty. While PDX tumor models are crucial for gaining predictive ins...
NOV 08, 2022 | 8:00 AM
Date: November 08, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CEST) While flow cytometry shines by its flexibility, it requires a high level of expertise in antibody panel development,...
NOV 01, 2022 | 10:00 AM
Date: November 01, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 6:00pm (CET) Our laboratory developed the Pig-a gene mutation assay as a means to simply and reliably evaluate the potential mutage...
OCT 19, 2022 | 6:45 AM
SARS-CoV-2 vaccine efficacy testing is now facing increasing challenges in the face of an ongoing pandemic with the emergence of new variants and waning vaccine immunity. Evidence supports t...