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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
OCT 12, 2022 | 8:30 PM
Date: October 12, 2022, October 13, 2022 Time: 8:30pm (PDT), 11:30pm (EDT), 5:30am (CEST) High dimensional full spectrum flow cytometry holds the promise of addressing long-held questions in...
OCT 04, 2022 | 7:00 AM
Date: October 04, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) The ability to derive induced pluripotent stem cells (iPSCs) from differentiated cell types such as fibroblasts, has r...
SEP 14, 2022 | 8:00 AM
Date: September 14, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) In this session, the benefits of combining in-line high speed imaging with flow cytometry will be explored. Acoustic...
AUG 16, 2022 | 9:00 AM
Date: August 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Combining our rich experience in molecular biology and cell system engineering, GenScript has established the TurboCHO&...
JUL 26, 2022 | 9:00 AM
Date: July 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Organoids and spheroids are increasingly being used in many research applications, including drug discovery, toxicology,...
JUN 29, 2022 | 10:00 PM
Date: June 30, 2022 Time: 3:00pm (AEST), 1:00pm (SGT), 2:00pm (JP/KR) Analyzing sea water is never an easy task. With high total dissolved solids (TDS), seawater is considered one of the mos...
JUN 28, 2022 | 9:00 PM
Date: June 29, 2022 Time: 12:00pm (PST), 2:00pm (EST), 8:00pm (CEST) The burden of antimicrobial resistance (AMR) has been acknowledged worldwide by leading health institutes. Besides the ne...
JUN 22, 2022 | 8:00 AM
Biopharmaceutical discovery, development and manufacturing requires the use of genetic analysis across the development continuum. Sanger sequencing and fragment analysis by capillary electro...
JUN 16, 2022 | 8:00 AM
Date: June 16, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Many researchers combine electrophysiological recordings with imaging applications, where a light source with high light...
JUN 01, 2022 | 9:00 AM
Date: June 01, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The manufacturing process for cell and gene therapies is complex and can contain process-related impurities from multiple...
MAY 26, 2022 | 9:00 AM
Date: May 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) In early drug development, lead clone selection requires large number of clones screening in cell line development. Develo...
MAY 25, 2022 | 10:00 AM
Date: May 25, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Programmable RNA base editors are excellent tools to modify RNA transcripts at precise locations or designated hotspots. P...
MAY 24, 2022 | 9:00 AM
Date: May 24, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Recent breakthroughs in autologous cellular therapies have generated tremendous excitement for the industry; however, thes...
MAY 18, 2022 | 9:00 AM
Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. The ability to swiftly develop novel therapies often depends...
MAY 03, 2022 | 8:00 AM
Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
APR 28, 2022 | 8:00 AM
Date: April 28, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Human pluripotent stem cells (PSCs) and their derivatives hold great potentials in...
APR 26, 2022 | 7:00 AM
Date: April 26, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CET) Cell competition is a mechanism of interaction that dictates cell selection based on differences in cellular fitness. We...
APR 20, 2022 | 12:00 PM
Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. The ability to swiftly develop novel therapies often depends...
APR 06, 2022 | 5:30 AM
Viral Vector gene therapy has been the focus of intense research driven by the safety profile and several clinical breakthroughs. As of March 2022, there are two viral vector gene therapies...
APR 06, 2022 | 5:30 AM
In the last decades, the upstream processing in biopharma industry has been revolutionized regarding the production of bioactive materials such as monoclonal antibodies, proteins and biother...
FEB 24, 2022 | 9:00 AM
Date: February 24, 2021 Time: 9:00am (PST), 12:00pm (EST) Cytokine profiling is a valuable tool used in preclinical research for monitoring an immune response and cell signaling pathways dur...
FEB 23, 2022 | 3:00 PM
Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
APR 06, 2022 | 5:30 AM
Viral Vector gene therapy has been the focus of intense research driven by the safety profile and several clinical breakthroughs. As of March 2022, there are two viral vector gene therapies...