CRISPR-Cas9
CRISPR-Cas9: Clustered regularly interspaced short palindromic repeats are segments of prokaryotic DNA containing short, repetitive base sequences. These play a key role in a bacterial defence system,and form the basis of a genome editing technology known as CRISPR/Cas9 that allows permanent modification of genes within organisms. The CRISPR/Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as those present within plasmids and phages that provides a form of acquired immunity. It is a unique technology that enables geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the DNA sequence.
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FEB 05, 2020Clinical & Molecular DX
FEB 05, 2020A surge in infections has caused panic surrounding the coronavirus (2019-nCoV) outbreak to reach a fever pitch. Despite being only moderately infective, 20...WRITTEN BY: Tara FernandezJAN 28, 2020Genetics & Genomics
JAN 28, 2020Because of a genetic mutation, people that have Duchenne muscular dystrophy lack functional copies of a protein called dystrophin....WRITTEN BY: Carmen LeitchDEC 25, 2019Genetics & Genomics
DEC 25, 2019A team of researchers from New York’s Cold Spring Harbor Laboratory have created a new strain of tomatoes that can grow from bushes rather than vines...WRITTEN BY: Annie LennonDEC 23, 2019Genetics & Genomics
DEC 23, 2019Muscles have a supply of restorative stem cells called satellite cells, and now they have identified a new type....WRITTEN BY: Carmen LeitchDEC 20, 2019Genetics & Genomics
DEC 20, 2019Down’s Syndrome (DS) is a genetic disorder brought on by the presence of all of part of a third copy of chromosome 21. Linked to delays in physical g...WRITTEN BY: Annie LennonDEC 15, 2019Genetics & Genomics
DEC 15, 2019Curated w/video - CRISPR/Cas9 deletion of an enzyme resulted in longer lasting, more robust therapy....WRITTEN BY: Carmen LeitchDEC 10, 2019Genetics & Genomics
DEC 10, 2019Last year, Chinese scientist He Jiankui caused tremendous controversy in the scientific world by conducting a gene-editing experiment on humans....WRITTEN BY: Carmen LeitchDEC 07, 2019Genetics & Genomics
DEC 07, 2019CRISPR is one of the most promising technologies under development to treat deadly inherited conditions such as cystic fibrosis and sickle cell disease. No...WRITTEN BY: Annie LennonDEC 01, 2019Cell & Molecular Biology
DEC 01, 2019Since the CRISPR gene editor was created, researchers around the world have tweaked and refined the tool to use it in a variety of ways....WRITTEN BY: Carmen LeitchNOV 03, 2019Genetics & Genomics
NOV 03, 2019Antibiotic-resistant infections claim around 700,000 lives per year, with estimates saying that this number could swell to 10 million by 2050 (Jacobs: 2019...WRITTEN BY: Annie LennonOCT 30, 2019Genetics & Genomics
OCT 30, 2019Researchers have learned why mutations in the ANT gene lead to heart problems....WRITTEN BY: Carmen LeitchOCT 22, 2019Cell & Molecular Biology
OCT 22, 2019A new technique enables researchers to target and modify one base pair out of billions, and could correct disease-causing mutations....WRITTEN BY: Carmen LeitchOCT 10, 2019Genetics & Genomics
OCT 10, 2019Researchers at the The Menzies Health Institute Queensland have found a way to use gene therapy CRISPR-Cas9 to treat cervical cancer. The first treatment o...WRITTEN BY: Annie LennonOCT 06, 2019Microbiology
OCT 06, 2019In recent years, the gene editing tool CRISPR/Cas9 has been applied to a wide variety of different organisms, and now, bacteria....WRITTEN BY: Carmen LeitchOCT 03, 2019Genetics & Genomics
OCT 03, 2019A more accurate version of Cas9 has been created, reducing the number of off-target effects. It may be better suited for use in gene therapy....WRITTEN BY: Carmen LeitchSEP 23, 2019Cell & Molecular Biology
SEP 23, 2019A team of scientists use fluorescently labeled proteins and CRISPR technology to image DNA transcription and chromosomal rearrangements....WRITTEN BY: Carly BoydSEP 20, 2019Neuroscience
SEP 20, 2019New drugs that seek to treat Alzheimer’s disease (AD) have a 99.6% failure rate. This makes it the only disease in the top 10 causes of death that ca...WRITTEN BY: Annie LennonSEP 11, 2019Genetics & Genomics
SEP 11, 2019CRISPR/Cas9 was developed as a gene-editing tool and now it's going beyond small, targeted changes in the genome....WRITTEN BY: Carmen LeitchAUG 30, 2019Health & Medicine
AUG 30, 2019Scientists at Edinburgh University’s Roslin Institute have created a flock of sheep that carry the gene for a heritable brain disorder in humans call...WRITTEN BY: Nina LichtenbergAUG 27, 2019Genetics & Genomics
AUG 27, 2019Efforts to edit the human genome are rolling forward, despite a call for a moratorium on heritable edits....WRITTEN BY: Carmen LeitchAUG 26, 2019Genetics & Genomics
AUG 26, 2019Until recently, many types of gene-editing methods were unable to target critical parts of DNA. Now however, researchers at the Salk Institute have develop...WRITTEN BY: Annie LennonAUG 23, 2019Genetics & Genomics
AUG 23, 2019Since it was developed, the CRISPR gene editing system has been refined and advanced....WRITTEN BY: Carmen LeitchAUG 18, 2019Genetics & Genomics
AUG 18, 2019There are challenges to working with nerve cells in the lab, which can create research bottlenecks in the study of neurological disease....WRITTEN BY: Carmen LeitchJUL 30, 2019Genetics & Genomics
JUL 30, 2019Many human diseases can be traced back to genetic mutations, and researchers are beginning to find ways to correct those errors....WRITTEN BY: Carmen Leitch
FEB 05, 2020
Clinical & Molecular DX
FEB 05, 2020
A surge in infections has caused panic surrounding the coronavirus (2019-nCoV) outbreak to reach a fever pitch. Despite being only moderately infective, 20...
WRITTEN BY:
Tara Fernandez
JAN 28, 2020
Genetics & Genomics
JAN 28, 2020
Because of a genetic mutation, people that have Duchenne muscular dystrophy lack functional copies of a protein called dystrophin....
WRITTEN BY:
Carmen Leitch
DEC 25, 2019
Genetics & Genomics
DEC 25, 2019
A team of researchers from New York’s Cold Spring Harbor Laboratory have created a new strain of tomatoes that can grow from bushes rather than vines...
WRITTEN BY:
Annie Lennon
DEC 23, 2019
Genetics & Genomics
DEC 23, 2019
Muscles have a supply of restorative stem cells called satellite cells, and now they have identified a new type....
WRITTEN BY:
Carmen Leitch
DEC 20, 2019
Genetics & Genomics
DEC 20, 2019
Down’s Syndrome (DS) is a genetic disorder brought on by the presence of all of part of a third copy of chromosome 21. Linked to delays in physical g...
WRITTEN BY:
Annie Lennon
DEC 15, 2019
Genetics & Genomics
DEC 15, 2019
Curated w/video - CRISPR/Cas9 deletion of an enzyme resulted in longer lasting, more robust therapy....
WRITTEN BY:
Carmen Leitch
DEC 10, 2019
Genetics & Genomics
DEC 10, 2019
Last year, Chinese scientist He Jiankui caused tremendous controversy in the scientific world by conducting a gene-editing experiment on humans....
WRITTEN BY:
Carmen Leitch
DEC 07, 2019
Genetics & Genomics
DEC 07, 2019
CRISPR is one of the most promising technologies under development to treat deadly inherited conditions such as cystic fibrosis and sickle cell disease. No...
WRITTEN BY:
Annie Lennon
DEC 01, 2019
Cell & Molecular Biology
DEC 01, 2019
Since the CRISPR gene editor was created, researchers around the world have tweaked and refined the tool to use it in a variety of ways....
WRITTEN BY:
Carmen Leitch
NOV 03, 2019
Genetics & Genomics
NOV 03, 2019
Antibiotic-resistant infections claim around 700,000 lives per year, with estimates saying that this number could swell to 10 million by 2050 (Jacobs: 2019...
WRITTEN BY:
Annie Lennon
OCT 30, 2019
Genetics & Genomics
OCT 30, 2019
Researchers have learned why mutations in the ANT gene lead to heart problems....
WRITTEN BY:
Carmen Leitch
OCT 22, 2019
Cell & Molecular Biology
OCT 22, 2019
A new technique enables researchers to target and modify one base pair out of billions, and could correct disease-causing mutations....
WRITTEN BY:
Carmen Leitch
OCT 10, 2019
Genetics & Genomics
OCT 10, 2019
Researchers at the The Menzies Health Institute Queensland have found a way to use gene therapy CRISPR-Cas9 to treat cervical cancer. The first treatment o...
WRITTEN BY:
Annie Lennon
OCT 06, 2019
Microbiology
OCT 06, 2019
In recent years, the gene editing tool CRISPR/Cas9 has been applied to a wide variety of different organisms, and now, bacteria....
WRITTEN BY:
Carmen Leitch
OCT 03, 2019
Genetics & Genomics
OCT 03, 2019
A more accurate version of Cas9 has been created, reducing the number of off-target effects. It may be better suited for use in gene therapy....
WRITTEN BY:
Carmen Leitch
SEP 23, 2019
Cell & Molecular Biology
SEP 23, 2019
A team of scientists use fluorescently labeled proteins and CRISPR technology to image DNA transcription and chromosomal rearrangements....
WRITTEN BY:
Carly Boyd
SEP 20, 2019
Neuroscience
SEP 20, 2019
New drugs that seek to treat Alzheimer’s disease (AD) have a 99.6% failure rate. This makes it the only disease in the top 10 causes of death that ca...
WRITTEN BY:
Annie Lennon
SEP 11, 2019
Genetics & Genomics
SEP 11, 2019
CRISPR/Cas9 was developed as a gene-editing tool and now it's going beyond small, targeted changes in the genome....
WRITTEN BY:
Carmen Leitch
AUG 30, 2019
Health & Medicine
AUG 30, 2019
Scientists at Edinburgh University’s Roslin Institute have created a flock of sheep that carry the gene for a heritable brain disorder in humans call...
WRITTEN BY:
Nina Lichtenberg
AUG 27, 2019
Genetics & Genomics
AUG 27, 2019
Efforts to edit the human genome are rolling forward, despite a call for a moratorium on heritable edits....
WRITTEN BY:
Carmen Leitch
AUG 26, 2019
Genetics & Genomics
AUG 26, 2019
Until recently, many types of gene-editing methods were unable to target critical parts of DNA. Now however, researchers at the Salk Institute have develop...
WRITTEN BY:
Annie Lennon
AUG 23, 2019
Genetics & Genomics
AUG 23, 2019
Since it was developed, the CRISPR gene editing system has been refined and advanced....
WRITTEN BY:
Carmen Leitch
AUG 18, 2019
Genetics & Genomics
AUG 18, 2019
There are challenges to working with nerve cells in the lab, which can create research bottlenecks in the study of neurological disease....
WRITTEN BY:
Carmen Leitch
JUL 30, 2019
Genetics & Genomics
JUL 30, 2019
Many human diseases can be traced back to genetic mutations, and researchers are beginning to find ways to correct those errors....
WRITTEN BY:
Carmen Leitch
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