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    CRISPR

    CRISPR is an abbreviation of Clustered Regularly Interspaced Short Palindromic Repeats. The name was minted at a time when the origin and use of the interspacing subsequences were not known. At that time the CRISPRs were described as segments of prokaryotic DNA containing short, repetitive base sequences. In a palindromic repeat, the sequence of nucleotides is the same in both directions. Each repetition is followed by short segments of spacer DNA from previous exposures to foreign DNA (e.g., a virus or plasmid). Small clusters of cas (CRISPR-associated) genes are located next to CRISPR sequences.

    Trending News

    • SEP 29, 2015
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      A scientific team including the scientist who first harnessed the CRISPR-Cas9 system for mammalian genome editing has re ...
      Written By: Ilene Schneider
      2
      MAY 01, 2015
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      The US Takes a Stance against Modifying Embryo DNA
      The US Takes a Stance against Modifying Embryo DNA
      Given new advances in genetic engineering, we now have the ability to edit DNA better than ever before. As part of havin ...
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      APR 23, 2015
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      Editing Human Embryos: A Brief History
      Editing Human Embryos: A Brief History
      In light of recent developments, New York Times columnist Carl Zimmer offered this perspective on National Geographic's ...
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      2
      APR 22, 2015
      Genetics & Genomics
      Chinese Scientists Genetically Altered Human Embryos
      Chinese Scientists Genetically Altered Human Embryos
      Results published in Protein & Cell, an open access journal, confirm rumors that Chinese scientists have edited genomes ...
      Written By: Judy O'Rourke
      2
      APR 22, 2015
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      Steering the epigenome to turn on specific genes
      Steering the epigenome to turn on specific genes
      Could the epigenome provide a new avenue for gene therapies and guiding stem cell differentiation?

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      APR 14, 2015
      Microbiology
      Self vs Non-Self: Bacteria Have an Immune System, too
      Self vs Non-Self: Bacteria Have an Immune System, too
      How bacterial cells recognize their own DNA.

      It may come as a bit of a surprise to learn that bacteria have a ...
      Written By: Robert Woodard
      4
      APR 08, 2015
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      Possible New RNA Engineering Tool
      Possible New RNA Engineering Tool
      Berkeley Researchers Report on CRISPR-Cas Surveillance Complex that Targets RNA.

      A great deal of public atten ...
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      1
      APR 02, 2015
      Genetics & Genomics
      Team Identifies Efficient New Cas9 for In Vivo Genome Editing
      Team Identifies Efficient New Cas9 for In Vivo Genome Editing
      A collaborative study between researchers from the Broad Institute of MIT and Harvard, Massachusetts Institute of Techno ...
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      APR 02, 2015
      Genetics & Genomics
      New Sickle Cell Gene Therapy Approaches
      New Sickle Cell Gene Therapy Approaches
      As a patient prepares to become the first in history to receive his own genetically engineered stem cells for sickle cel ...
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      APR 02, 2015
      Cancer
      New Evidence for How a Rare Form of Liver Cancer Arises
      New Evidence for How a Rare Form of Liver Cancer Arises
      In the 1970s, epidemiologists found that workers in factories using vinyl chloride, the key ingredient for PVC plastics, ...
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      4
      MAR 27, 2015
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      Researchers Master Gene Editing Technique in Mosquito
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      MAR 27, 2015
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      MAR 24, 2015
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      MAR 23, 2015
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      Welcome back old friend
      Welcome back old friend
      Scientists at Harvard University are one step closer to bringing Woolly mammoths back to life, after successfully insert ...
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      MAR 19, 2015
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      Sickle Cell Drug Offers "Overwhelming" Gains as "Exciting" Stem Cell Trial Starts
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      AUG 06, 2014
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    SEP 29, 2015
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    Gauging Genomic Gain
    Gauging Genomic Gain
    A scientific team including the scientist who first harnessed the CRISPR-Cas9 system for mammalian genome editing has re ...
    Written By: Ilene Schneider
    2
    MAY 01, 2015
    Genetics & Genomics
    The US Takes a Stance against Modifying Embryo DNA
    The US Takes a Stance against Modifying Embryo DNA
    Given new advances in genetic engineering, we now have the ability to edit DNA better than ever before. As part of havin ...
    Written By: Jennifer Ellis
    3
    APR 23, 2015
    Genetics & Genomics
    Editing Human Embryos: A Brief History
    Editing Human Embryos: A Brief History
    In light of recent developments, New York Times columnist Carl Zimmer offered this perspective on National Geographic's ...
    Written By: Robert Woodard
    2
    APR 22, 2015
    Genetics & Genomics
    Chinese Scientists Genetically Altered Human Embryos
    Chinese Scientists Genetically Altered Human Embryos
    Results published in Protein & Cell, an open access journal, confirm rumors that Chinese scientists have edited genomes ...
    Written By: Judy O'Rourke
    2
    APR 22, 2015
    Genetics & Genomics
    Steering the epigenome to turn on specific genes
    Steering the epigenome to turn on specific genes
    Could the epigenome provide a new avenue for gene therapies and guiding stem cell differentiation?

    Written By: Robert Woodard
    5
     
     
  • APR 14, 2015
    Microbiology
    Self vs Non-Self: Bacteria Have an Immune System, too
    Self vs Non-Self: Bacteria Have an Immune System, too
    How bacterial cells recognize their own DNA.

    It may come as a bit of a surprise to learn that bacteria have a ...
    Written By: Robert Woodard
    4
    APR 08, 2015
    Immunology
    Possible New RNA Engineering Tool
    Possible New RNA Engineering Tool
    Berkeley Researchers Report on CRISPR-Cas Surveillance Complex that Targets RNA.

    A great deal of public atten ...
    Written By: Robert Woodard
    1
    APR 02, 2015
    Genetics & Genomics
    Team Identifies Efficient New Cas9 for In Vivo Genome Editing
    Team Identifies Efficient New Cas9 for In Vivo Genome Editing
    A collaborative study between researchers from the Broad Institute of MIT and Harvard, Massachusetts Institute of Techno ...
    Written By: Ilene Schneider
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    APR 02, 2015
    Genetics & Genomics
    New Sickle Cell Gene Therapy Approaches
    New Sickle Cell Gene Therapy Approaches
    As a patient prepares to become the first in history to receive his own genetically engineered stem cells for sickle cel ...
    Written By: Ilene Schneider
    4
    APR 02, 2015
    Cancer
    New Evidence for How a Rare Form of Liver Cancer Arises
    New Evidence for How a Rare Form of Liver Cancer Arises
    In the 1970s, epidemiologists found that workers in factories using vinyl chloride, the key ingredient for PVC plastics, ...
    Written By: Ilene Schneider
    4
     
     
  • MAR 27, 2015
    Genetics & Genomics
    Researchers Master Gene Editing Technique in Mosquito
    Researchers Master Gene Editing Technique in Mosquito
    Traditionally, to understand how a gene functions, a scientist would breed an organism that lacks that gene - "knocking ...
    Written By: Ilene Schneider
    3
    MAR 27, 2015
    Genetics & Genomics
    CRISPR Genome-Edited Piglets
    CRISPR Genome-Edited Piglets
    Eighteen piglets born recently are the result of two years of intense research by scientists in the College of Agricultu ...
    Written By: Judy O'Rourke
    5
    MAR 24, 2015
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    Scientists Call for Freeze on Genome-Editing Method
    Scientists Call for Freeze on Genome-Editing Method
    Designer babies? It's far from a whimsy, and now a new technology that would make it possible to alter human DNA at the ...
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    MAR 23, 2015
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    Welcome back old friend
    Welcome back old friend
    Scientists at Harvard University are one step closer to bringing Woolly mammoths back to life, after successfully insert ...
    Written By: Robert Woodard
    4
    MAR 19, 2015
    Genetics & Genomics
    Sickle Cell Drug Offers "Overwhelming" Gains as "Exciting" Stem Cell Trial Starts
    Sickle Cell Drug Offers "Overwhelming" Gains as "Exciting" Stem Cell Trial Starts
    A clinical trial of the most common sickle cell anemia drug, hydroxyurea, was halted a year early this winter because of ...
    Written By: Ilene Schneider
    3
     
     
  • FEB 27, 2015
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    Enzyme Cues Bacteria to Recall a Peril
    Enzyme Cues Bacteria to Recall a Peril
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    AUG 06, 2014
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    We Can Change the World. Oops!
    We Can Change the World. Oops!
    In a paper entitled, Concerning RNA-Guided Gene Drives for the Alteration of Wild Populations, recently published in eLi ...
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