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    Follow

    CRISPR

    CRISPR is an abbreviation of Clustered Regularly Interspaced Short Palindromic Repeats. The name was minted at a time when the origin and use of the interspacing subsequences were not known. At that time the CRISPRs were described as segments of prokaryotic DNA containing short, repetitive base sequences. In a palindromic repeat, the sequence of nucleotides is the same in both directions. Each repetition is followed by short segments of spacer DNA from previous exposures to foreign DNA (e.g., a virus or plasmid). Small clusters of cas (CRISPR-associated) genes are located next to CRISPR sequences.

    Trending News

    • MAY 24, 2020
      Genetics & Genomics
      How CRISPR Can Aid in Wildlife Conservation
      How CRISPR Can Aid in Wildlife Conservation
      Since it was developed, researchers have modified and applied the CRISPR gene editing technology in many different ways.
      Written By: Carmen Leitch
      2
      MAY 14, 2020
      Genetics & Genomics
      Tracking Single Cells as They Build an Adult Organism
      Tracking Single Cells as They Build an Adult Organism
      Organisms develop from a single cell that gives rise to all the different kinds of tissues and structures that are found ...
      Written By: Carmen Leitch
      1
      APR 23, 2020
      Drug Discovery & Development
      Making Recombination-Protein Drugs Cost Effective
      Making Recombination-Protein Drugs Cost Effective
        In a study published in Nature Communications, scientists used genome-editing techniques to eliminate up to 70 pe ...
      Written By: Nouran Amin
      1
      APR 13, 2020
      Cell & Molecular Biology
      Getting Closer to Making Heparin in Cells
      Getting Closer to Making Heparin in Cells
      While heparin is the most commonly prescribed drug in hospitals, we have to extract it from pig intestines, which is fra ...
      Written By: Carmen Leitch
      1
      APR 09, 2020
      Cell & Molecular Biology
      A Model of Spinal Development Provides Insight Into Disease
      A Model of Spinal Development Provides Insight Into Disease
      The spinal column develops from a row of structures called somites, which bud off sequentially in a process called somit ...
      Written By: Carmen Leitch
      1
      MAR 28, 2020
      Cancer
      The Not So Minor Genetic Players in Head and Neck Cancers
      The Not So Minor Genetic Players in Head and Neck Cancers
      Head and neck squamous cell carcinomas (HNSCC) are among the most prevalent cancers among smokers, linked to alcohol con ...
      Written By: Jasper Cantrell
      1
      MAR 27, 2020
      Genetics & Genomics
      Expanding the Genomic Regions That Can Be Targeted With CRISPR
      Expanding the Genomic Regions That Can Be Targeted With CRISPR
      CRISPR gene-editing technology has sparked a revolution in biomedical research and is poised to have far-reaching applic ...
      Written By: Carmen Leitch
      2
      MAR 17, 2020
      Genetics & Genomics
      Targeting RNA With CRISPR
      Targeting RNA With CRISPR
      Researchers screened thousands of target molecules to find the most effective targets, and have made their data openly a ...
      Written By: Carmen Leitch
      1
      MAR 04, 2020
      Cell & Molecular Biology
      CRISPR Used Inside of a Patient For the First Time
      CRISPR Used Inside of a Patient For the First Time
      In a first, scientists have used the CRISPR gene-editing tool inside of a person's body to treat a serious eye disorder.
      Written By: Carmen Leitch
      2
      MAR 03, 2020
      Cell & Molecular Biology
      New CRISPR-HOT Technique Can Color Cells and Genes
      New CRISPR-HOT Technique Can Color Cells and Genes
      Since the CRISPR/Cas9 editing tool was developed several years ago, many scientists have modified and improved it for di ...
      Written By: Carmen Leitch
      1
      FEB 17, 2020
      Microbiology
      Giant Viruses Blur the Line Between Life and Non-Life
      Giant Viruses Blur the Line Between Life and Non-Life
      Bacteriophages, also known as phages, are more complex than many viruses that we know of, and often carry large genomes.
      Written By: Carmen Leitch
      1
      FEB 16, 2020
      Plants & Animals
      These Jellyfish Deliver Stings Without Touching You
      These Jellyfish Deliver Stings Without Touching You
      Most people are accustomed to thinking that if you avoid a jellyfish’s tentacles while swimming in the ocean, then ...
      Written By: Anthony Bouchard
      2
      FEB 05, 2020
      Clinical & Molecular DX
      A new CRISPR-based test for coronavirus infections
      A new CRISPR-based test for coronavirus infections
      A surge in infections has caused panic surrounding the coronavirus (2019-nCoV) outbreak to reach a fever pitch. Despite ...
      Written By: Tara Fernandes
      1
      JAN 28, 2020
      Genetics & Genomics
      Developing a Gene Therapy to Treat Duchenne Muscular Dystrophy
      Developing a Gene Therapy to Treat Duchenne Muscular Dystrophy
      Because of a genetic mutation, people that have Duchenne muscular dystrophy lack functional copies of a protein called d ...
      Written By: Carmen Leitch
      1
      JAN 19, 2020
      Genetics & Genomics
      Engineering Mosquitoes to Stop Dengue Virus Transmission
      Engineering Mosquitoes to Stop Dengue Virus Transmission
      The dengue virus is transmitted by mosquitoes. It is found in over one hundred countries and threatens three billion peo ...
      Written By: Carmen Leitch
      1
      JAN 13, 2020
      Cell & Molecular Biology
      Disrupting Leukemia's Deadly Reliance on Vitamin B6
      Disrupting Leukemia's Deadly Reliance on Vitamin B6
      Acute Myeloid Leukemia is a cancer of the blood that starts in the bone marrow, where the stem cells that produce blood ...
      Written By: Carmen Leitch
      1
      DEC 31, 2019
      Genetics & Genomics
      Should the Scientist Behind World's First Gene Edited Babies be in Prison?
      Should the Scientist Behind World's First Gene Edited Babies be in Prison?
      He Jiankui, the scientist behind the world’s first gene-edited babies in 2018, has been sentenced to three years i ...
      Written By: Annie Lennon
      1
      DEC 25, 2019
      Genetics & Genomics
      Perfect for Urban Farming: Gene-Edited Tomatoes that Grow like Grapes
      Perfect for Urban Farming: Gene-Edited Tomatoes that Grow like Grapes
      A team of researchers from New York’s Cold Spring Harbor Laboratory have created a new strain of tomatoes that can ...
      Written By: Annie Lennon
      2
      DEC 23, 2019
      Genetics & Genomics
      A New Type of Muscle Cell That Could be a Target for Gene Therapy is ID'ed
      A New Type of Muscle Cell That Could be a Target for Gene Therapy is ID'ed
      Muscles have a supply of restorative stem cells called satellite cells, and now they have identified a new type.
      Written By: Carmen Leitch
      1
      DEC 22, 2019
      Microbiology
      Viruses Can Escape the Effects of CRISPR by Shielding Their Genomes
      Viruses Can Escape the Effects of CRISPR by Shielding Their Genomes
      Our world is filled with microbes, and in every kind of environment, they compete for supremacy, a competition that date ...
      Written By: Carmen Leitch
      2
      DEC 20, 2019
      Genetics & Genomics
      Can We Cure Down's Syndrome with Gene Therapy?
      Can We Cure Down's Syndrome with Gene Therapy?
      Down’s Syndrome (DS) is a genetic disorder brought on by the presence of all of part of a third copy of chromosome ...
      Written By: Annie Lennon
      1
      DEC 15, 2019
      Genetics & Genomics
      Making T-Cell Therapy Even More Effective
      Making T-Cell Therapy Even More Effective
      Curated w/video - CRISPR/Cas9 deletion of an enzyme resulted in longer lasting, more robust therapy.
      Written By: Carmen Leitch
      1
      DEC 10, 2019
      Genetics & Genomics
      The Fallout From the CRISPR Infant Experiment Continues
      The Fallout From the CRISPR Infant Experiment Continues
      Last year, Chinese scientist He Jiankui caused tremendous controversy in the scientific world by conducting a gene-editi ...
      Written By: Carmen Leitch
      1
      DEC 07, 2019
      Genetics & Genomics
      New Tool Rapidly Detects Unintended Gene Changes from CRISPR
      New Tool Rapidly Detects Unintended Gene Changes from CRISPR
      CRISPR is one of the most promising technologies under development to treat deadly inherited conditions such as cystic f ...
      Written By: Annie Lennon
      1
    MAY 24, 2020
    Genetics & Genomics
    How CRISPR Can Aid in Wildlife Conservation
    How CRISPR Can Aid in Wildlife Conservation
    Since it was developed, researchers have modified and applied the CRISPR gene editing technology in many different ways.
    Written By: Carmen Leitch
    2
    MAY 14, 2020
    Genetics & Genomics
    Tracking Single Cells as They Build an Adult Organism
    Tracking Single Cells as They Build an Adult Organism
    Organisms develop from a single cell that gives rise to all the different kinds of tissues and structures that are found ...
    Written By: Carmen Leitch
    1
    APR 23, 2020
    Drug Discovery & Development
    Making Recombination-Protein Drugs Cost Effective
    Making Recombination-Protein Drugs Cost Effective
      In a study published in Nature Communications, scientists used genome-editing techniques to eliminate up to 70 pe ...
    Written By: Nouran Amin
    1
    APR 13, 2020
    Cell & Molecular Biology
    Getting Closer to Making Heparin in Cells
    Getting Closer to Making Heparin in Cells
    While heparin is the most commonly prescribed drug in hospitals, we have to extract it from pig intestines, which is fra ...
    Written By: Carmen Leitch
    1
    APR 09, 2020
    Cell & Molecular Biology
    A Model of Spinal Development Provides Insight Into Disease
    A Model of Spinal Development Provides Insight Into Disease
    The spinal column develops from a row of structures called somites, which bud off sequentially in a process called somit ...
    Written By: Carmen Leitch
    1
     
     
  • MAR 28, 2020
    Cancer
    The Not So Minor Genetic Players in Head and Neck Cancers
    The Not So Minor Genetic Players in Head and Neck Cancers
    Head and neck squamous cell carcinomas (HNSCC) are among the most prevalent cancers among smokers, linked to alcohol con ...
    Written By: Jasper Cantrell
    1
    MAR 27, 2020
    Genetics & Genomics
    Expanding the Genomic Regions That Can Be Targeted With CRISPR
    Expanding the Genomic Regions That Can Be Targeted With CRISPR
    CRISPR gene-editing technology has sparked a revolution in biomedical research and is poised to have far-reaching applic ...
    Written By: Carmen Leitch
    2
    MAR 17, 2020
    Genetics & Genomics
    Targeting RNA With CRISPR
    Targeting RNA With CRISPR
    Researchers screened thousands of target molecules to find the most effective targets, and have made their data openly a ...
    Written By: Carmen Leitch
    1
    MAR 04, 2020
    Cell & Molecular Biology
    CRISPR Used Inside of a Patient For the First Time
    CRISPR Used Inside of a Patient For the First Time
    In a first, scientists have used the CRISPR gene-editing tool inside of a person's body to treat a serious eye disorder.
    Written By: Carmen Leitch
    2
    MAR 03, 2020
    Cell & Molecular Biology
    New CRISPR-HOT Technique Can Color Cells and Genes
    New CRISPR-HOT Technique Can Color Cells and Genes
    Since the CRISPR/Cas9 editing tool was developed several years ago, many scientists have modified and improved it for di ...
    Written By: Carmen Leitch
    1
     
     
  • FEB 17, 2020
    Microbiology
    Giant Viruses Blur the Line Between Life and Non-Life
    Giant Viruses Blur the Line Between Life and Non-Life
    Bacteriophages, also known as phages, are more complex than many viruses that we know of, and often carry large genomes.
    Written By: Carmen Leitch
    1
    FEB 16, 2020
    Plants & Animals
    These Jellyfish Deliver Stings Without Touching You
    These Jellyfish Deliver Stings Without Touching You
    Most people are accustomed to thinking that if you avoid a jellyfish’s tentacles while swimming in the ocean, then ...
    Written By: Anthony Bouchard
    2
    FEB 05, 2020
    Clinical & Molecular DX
    A new CRISPR-based test for coronavirus infections
    A new CRISPR-based test for coronavirus infections
    A surge in infections has caused panic surrounding the coronavirus (2019-nCoV) outbreak to reach a fever pitch. Despite ...
    Written By: Tara Fernandes
    1
    JAN 28, 2020
    Genetics & Genomics
    Developing a Gene Therapy to Treat Duchenne Muscular Dystrophy
    Developing a Gene Therapy to Treat Duchenne Muscular Dystrophy
    Because of a genetic mutation, people that have Duchenne muscular dystrophy lack functional copies of a protein called d ...
    Written By: Carmen Leitch
    1
    JAN 19, 2020
    Genetics & Genomics
    Engineering Mosquitoes to Stop Dengue Virus Transmission
    Engineering Mosquitoes to Stop Dengue Virus Transmission
    The dengue virus is transmitted by mosquitoes. It is found in over one hundred countries and threatens three billion peo ...
    Written By: Carmen Leitch
    1
     
     
  • JAN 13, 2020
    Cell & Molecular Biology
    Disrupting Leukemia's Deadly Reliance on Vitamin B6
    Disrupting Leukemia's Deadly Reliance on Vitamin B6
    Acute Myeloid Leukemia is a cancer of the blood that starts in the bone marrow, where the stem cells that produce blood ...
    Written By: Carmen Leitch
    1
    DEC 31, 2019
    Genetics & Genomics
    Should the Scientist Behind World's First Gene Edited Babies be in Prison?
    Should the Scientist Behind World's First Gene Edited Babies be in Prison?
    He Jiankui, the scientist behind the world’s first gene-edited babies in 2018, has been sentenced to three years i ...
    Written By: Annie Lennon
    1
    DEC 25, 2019
    Genetics & Genomics
    Perfect for Urban Farming: Gene-Edited Tomatoes that Grow like Grapes
    Perfect for Urban Farming: Gene-Edited Tomatoes that Grow like Grapes
    A team of researchers from New York’s Cold Spring Harbor Laboratory have created a new strain of tomatoes that can ...
    Written By: Annie Lennon
    2
    DEC 23, 2019
    Genetics & Genomics
    A New Type of Muscle Cell That Could be a Target for Gene Therapy is ID'ed
    A New Type of Muscle Cell That Could be a Target for Gene Therapy is ID'ed
    Muscles have a supply of restorative stem cells called satellite cells, and now they have identified a new type.
    Written By: Carmen Leitch
    1
    DEC 22, 2019
    Microbiology
    Viruses Can Escape the Effects of CRISPR by Shielding Their Genomes
    Viruses Can Escape the Effects of CRISPR by Shielding Their Genomes
    Our world is filled with microbes, and in every kind of environment, they compete for supremacy, a competition that date ...
    Written By: Carmen Leitch
    2
     
     
  • DEC 20, 2019
    Genetics & Genomics
    Can We Cure Down's Syndrome with Gene Therapy?
    Can We Cure Down's Syndrome with Gene Therapy?
    Down’s Syndrome (DS) is a genetic disorder brought on by the presence of all of part of a third copy of chromosome ...
    Written By: Annie Lennon
    1
    DEC 15, 2019
    Genetics & Genomics
    Making T-Cell Therapy Even More Effective
    Making T-Cell Therapy Even More Effective
    Curated w/video - CRISPR/Cas9 deletion of an enzyme resulted in longer lasting, more robust therapy.
    Written By: Carmen Leitch
    1
    DEC 10, 2019
    Genetics & Genomics
    The Fallout From the CRISPR Infant Experiment Continues
    The Fallout From the CRISPR Infant Experiment Continues
    Last year, Chinese scientist He Jiankui caused tremendous controversy in the scientific world by conducting a gene-editi ...
    Written By: Carmen Leitch
    1
    DEC 07, 2019
    Genetics & Genomics
    New Tool Rapidly Detects Unintended Gene Changes from CRISPR
    New Tool Rapidly Detects Unintended Gene Changes from CRISPR
    CRISPR is one of the most promising technologies under development to treat deadly inherited conditions such as cystic f ...
    Written By: Annie Lennon
    1
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