Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
If your lab has decided to apply for ISO/IEC 17025 accreditation as your state requires it or to demonstrate the reliability of your lab results to potential customers, you may think what nex...
The cannabis industry has realized that not just one or two compounds of the plant are important for a variety of medical indications. A plethora of metabolites, e.g. terpenes, flavonoids and...
With the legalization process currently taking place in the US, finding new techniques for the fast, cheap, and comprehensive analysis of Cannabis sativa components has become a major point o...
Building and production management systems are creating massive amounts of data related to growing cannabis. This presents the opportunity for growers to use machine learning (ML) tools to su...
In this panel discussion, parents of medically compromised children using cannabis discuss their experiences of what led them to start cannabis therapy, what delivery methods they currently u...
In recent years, many countries have passed legislation regulating the use of cannabis for medical purposes. This has granted patients and clinicians access to both herbal material and cannab...
Imagine the need for agriculture being removed completely from the cannabis supply chain.Cellibre’s vision is to leverage biology to make products more sustainable, efficiently and...
Cannabis sativa is an herbaceous plant of high interest, with applications of the plant and its products varied and ripe with investment. The Cannabis industry experienced a new surge of busi...
Dr. Sulak will review the evidence supporting the use of cannabis to not only treat serious disease, but to prevent them and maintain health, with practical and easy to implement dosing strat...
Automating Cannabis Testing with Laboratory Information Management Systems (LIMS) Software systems automate not only key aspects of laboratory testing, but provide a comprehensive data manage...
There are currently 33 states and the District of Columbia that have legalized medical marijuana. The research supporting its medical use, however, lags behind current policy efforts. This ta...
The use of cannabis to treat the symptoms of cancer and associated treatments is well known, but a growing body of evidence shows how cannabis can also be used as a direct anticancer agent. I...
DATE: March 26, 2019TIME: 2:00pm PDT, 5:00pm EDT Prostate cancer is the second most common form of cancer in males, affecting one in eight men by the time t...
In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
Whether you are performing killing assays, immunophenotyping of TILs, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery...
Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
Isolated hepatocytes or their enzymes comprise the basis of most in vitro DMPK and toxicity assays used to predict human hepatic outcomes. Because hepato-specific functions are typically lost...
Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
Small size, highly selective nature, flexible chemistry and ease of manufacturing make nucleic acid aptamers attractive for multiple applications in human diagnostics and drug discovery. &nbs...
NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...
If your lab has decided to apply for ISO/IEC 17025 accreditation as your state requires it or to demonstrate the reliability of your lab results to potential customers, you may think what nex...
The cannabis industry has realized that not just one or two compounds of the plant are important for a variety of medical indications. A plethora of metabolites, e.g. terpenes, flavonoids and...
With the legalization process currently taking place in the US, finding new techniques for the fast, cheap, and comprehensive analysis of Cannabis sativa components has become a major point o...
Building and production management systems are creating massive amounts of data related to growing cannabis. This presents the opportunity for growers to use machine learning (ML) tools to su...
In this panel discussion, parents of medically compromised children using cannabis discuss their experiences of what led them to start cannabis therapy, what delivery methods they currently u...
In recent years, many countries have passed legislation regulating the use of cannabis for medical purposes. This has granted patients and clinicians access to both herbal material and cannab...
Imagine the need for agriculture being removed completely from the cannabis supply chain.Cellibre’s vision is to leverage biology to make products more sustainable, efficiently and...
Cannabis sativa is an herbaceous plant of high interest, with applications of the plant and its products varied and ripe with investment. The Cannabis industry experienced a new surge of busi...
Dr. Sulak will review the evidence supporting the use of cannabis to not only treat serious disease, but to prevent them and maintain health, with practical and easy to implement dosing strat...
Automating Cannabis Testing with Laboratory Information Management Systems (LIMS) Software systems automate not only key aspects of laboratory testing, but provide a comprehensive data manage...
There are currently 33 states and the District of Columbia that have legalized medical marijuana. The research supporting its medical use, however, lags behind current policy efforts. This ta...
The use of cannabis to treat the symptoms of cancer and associated treatments is well known, but a growing body of evidence shows how cannabis can also be used as a direct anticancer agent. I...
DATE: March 26, 2019TIME: 2:00pm PDT, 5:00pm EDT Prostate cancer is the second most common form of cancer in males, affecting one in eight men by the time t...
In today's presentation I will give an overview to developing NextGen ADCs. We will discuss everything from the beginning stages of development to the varying ADC combination therapies av...
In-vitro epithelial barrier models that are more representative of in-vivo tissues are urgently needed. Here we present extracellular matrix-supported intestinal tubules in a perfused microfl...
Whether you are performing killing assays, immunophenotyping of TILs, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery...
Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
Isolated hepatocytes or their enzymes comprise the basis of most in vitro DMPK and toxicity assays used to predict human hepatic outcomes. Because hepato-specific functions are typically lost...
Cellular research is optimal when using physiologically-relevant cell phenotypes and genotypes of human origin. This assertion has accelerated the adoption of primary cells, stem cells, and i...
Small size, highly selective nature, flexible chemistry and ease of manufacturing make nucleic acid aptamers attractive for multiple applications in human diagnostics and drug discovery. &nbs...
NTRK fusions are rare but important recent biomarkers linked to response to new TRK inhibitors. Comprehensive genomic profiling on all solid tumors permits detection of rare genomic events an...