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High Content Screening
High Content Screening: a method that is used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell in a desired manner. Hence high content screening is a type of phenotypic screen conducted in cells. Phenotypic changes may include increases or decreases in the production of cellular products such as proteins and/or changes in the morphology (visual appearance) of the cell. High content screening includes any method used to analyze whole cells or components of cells with simultaneous readout of several parameters.
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DEC 27, 2017Drug Discovery & Development
various medicine chemistry toolsWritten By: Courtney SchaalDEC 24, 2017Drug Discovery & Development
Brief discussion of automation in compound discoveryWritten By: Courtney SchaalDEC 18, 2017Cardiology
Screening men with erectile dysfunction (ED) for traces of heart disease may help medical professionals reach low and in ...Written By: Kara MarkerDEC 17, 2017Cell & Molecular Biology
Microfilaments that are capable of conducting electricity, termed nanowires, were discovered in the bacterium Geobacter ...Written By: Carmen LeitchDEC 13, 2017Genetics & Genomics
Colorectal cancer is on the rise among young people, and researchers are working to learn what is behind the increase.Written By: Carmen LeitchDEC 01, 2017Drug Discovery & Development
Considerations and Limitations of High Throughput Screening for Drug DiscoveryWritten By: Courtney SchaalNOV 24, 2017Immunology
The majority of drugs available for people with autoimmune diseases are only designed to alleviate symptoms, as opposed ...Written By: Kara MarkerNOV 14, 2017Clinical & Molecular DX
Breathalyzers have come a long way. No longer are these devices only popular for the detection of drunk drivers. Instead ...NOV 13, 2017Clinical & Molecular DX
Repeat sequences are common in our DNA, and are known to cause human disorders. In particular, a triplet repeat on the X ...NOV 12, 2017Drug Discovery & Development
Bacteria has continued to evolve, becoming resistant to antibiotics, but scientists have found a screen to help combat t ...Written By: Courtney SchaalOCT 19, 2017Clinical & Molecular DX
In a new study, researchers found something alarming: The ethnic and racial group at one of the highest risk for diabete ...OCT 13, 2017Cancer
The link between vasectomies and prostate cancer is officially debunked. In a huge study of over 3 million men, scientis ...OCT 10, 2017Drug Discovery & Development
After nearly a decade of searching, scientists from the Albert Einstein College of Medicine have found a molecule that k ...SEP 27, 2017Neuroscience
It seems as if not a week goes by that football and head injuries aren't in the news. Most recently, it was announce ...Written By: Brenda Kelley KimSEP 16, 2017Cancer
Unlike some liquid biopsies that look for remnants of free-floating cancer DNA in the blood, scientists have designed a ...SEP 06, 2017Clinical & Molecular DX
Men, perhaps it's time to schedule a prostate screening exam with your doctor! New results from two eminent prostate ...AUG 19, 2017Cancer
For disease as complex as cancer, knowing a single mutation is sometimes not enough. In the case of lethal brain tumors, ...JUL 31, 2017Cancer
A study, published in the New England Journal of Medicine, examined DNA repair genes and whether mutations in these gene ...JUL 26, 2017Chemistry & Physics
Peptide and protein drugs like insulin are critical medications. Most of them cannot be taken orally because they will b ...Written By: Daniel DuanJUL 23, 2017Health & Medicine
In celebration of 4 decades of Assisted Reproductive Technology (ART) here's a roundup of 6 cutting edge technologies in ...Written By: Liat Ben-SeniorJUL 20, 2017Clinical & Molecular DX
Scientists may have found a way to screen for Alzheimer’s disease years before patients develop severe signs of ne ...JUL 17, 2017Cell & Molecular Biology
Bisphenol A (BPA) is used frequently in food packaging, and it has gotten into our bodies. New research could help repla ...Written By: Carmen LeitchJUL 05, 2017Cancer
It looks like a small pill attached to a long string. But scientists say the so-called “pill” may replace tr ...JUN 20, 2017Cardiology
For the first time, researchers report that a baby’s DNA influences a mother’s risk of pre-eclampsia, a cond ...Written By: Kara Marker
DEC 27, 2017
Drug Discovery & Development
various medicine chemistry tools
Written By:
Courtney Schaal
DEC 24, 2017
Drug Discovery & Development
Brief discussion of automation in compound discovery
Written By:
Courtney Schaal
DEC 18, 2017
Cardiology
Screening men with erectile dysfunction (ED) for traces of heart disease may help medical professionals reach low and in
...
Written By:
Kara Marker
DEC 17, 2017
Cell & Molecular Biology
Microfilaments that are capable of conducting electricity, termed nanowires, were discovered in the bacterium Geobacter
...
Written By:
Carmen Leitch
DEC 13, 2017
Genetics & Genomics
Colorectal cancer is on the rise among young people, and researchers are working to learn what is behind the increase.
Written By:
Carmen Leitch
DEC 01, 2017
Drug Discovery & Development
Considerations and Limitations of High Throughput Screening for Drug Discovery
Written By:
Courtney Schaal
NOV 24, 2017
Immunology
The majority of drugs available for people with autoimmune diseases are only designed to alleviate symptoms, as opposed
...
Written By:
Kara Marker
NOV 14, 2017
Clinical & Molecular DX
Breathalyzers have come a long way. No longer are these devices only popular for the detection of drunk drivers. Instead
...
NOV 13, 2017
Clinical & Molecular DX
Repeat sequences are common in our DNA, and are known to cause human disorders. In particular, a triplet repeat on the X
...
NOV 12, 2017
Drug Discovery & Development
Bacteria has continued to evolve, becoming resistant to antibiotics, but scientists have found a screen to help combat t
...
Written By:
Courtney Schaal
OCT 19, 2017
Clinical & Molecular DX
In a new study, researchers found something alarming: The ethnic and racial group at one of the highest risk for diabete
...
OCT 13, 2017
Cancer
The link between vasectomies and prostate cancer is officially debunked. In a huge study of over 3 million men, scientis
...
OCT 10, 2017
Drug Discovery & Development
After nearly a decade of searching, scientists from the Albert Einstein College of Medicine have found a molecule that k
...
SEP 27, 2017
Neuroscience
It seems as if not a week goes by that football and head injuries aren't in the news. Most recently, it was announce
...
Written By:
Brenda Kelley Kim
SEP 16, 2017
Cancer
Unlike some liquid biopsies that look for remnants of free-floating cancer DNA in the blood, scientists have designed a
...
SEP 06, 2017
Clinical & Molecular DX
Men, perhaps it's time to schedule a prostate screening exam with your doctor! New results from two eminent prostate
...
AUG 19, 2017
Cancer
For disease as complex as cancer, knowing a single mutation is sometimes not enough. In the case of lethal brain tumors,
...
JUL 31, 2017
Cancer
A study, published in the New England Journal of Medicine, examined DNA repair genes and whether mutations in these gene
...
JUL 26, 2017
Chemistry & Physics
Peptide and protein drugs like insulin are critical medications. Most of them cannot be taken orally because they will b
...
Written By:
Daniel Duan
JUL 23, 2017
Health & Medicine
In celebration of 4 decades of Assisted Reproductive Technology (ART) here's a roundup of 6 cutting edge technologies in
...
Written By:
Liat Ben-Senior
JUL 20, 2017
Clinical & Molecular DX
Scientists may have found a way to screen for Alzheimer’s disease years before patients develop severe signs of ne
...
JUL 17, 2017
Cell & Molecular Biology
Bisphenol A (BPA) is used frequently in food packaging, and it has gotten into our bodies. New research could help repla
...
Written By:
Carmen Leitch
JUL 05, 2017
Cancer
It looks like a small pill attached to a long string. But scientists say the so-called “pill” may replace tr
...
JUN 20, 2017
Cardiology
For the first time, researchers report that a baby’s DNA influences a mother’s risk of pre-eclampsia, a cond
...
Written By:
Kara Marker