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    Hypoxia

    Hypoxia: is the deprivation of oxygen to the brain, and is one of the deadliest wounds because of the deficiency in the amount of oxygen reaching the tissues.

    Webinars

    • DEC 07, 2023 | 8:00 AM
      Translating COSMIC's gold standard data into actionable insights
      Translating COSMIC's gold standard data into actionable insights
      As the vast landscape of genetic oncology continues to expand, the ability to understand and utilize the full potential of this rich data becomes increasingly challenging. As a result, resea...
      Speaker: Leonie Hodges , Alex Holmes, Ph.D. , Jennifer Wilding, Ph.D.
      Sponsored By: QIAGEN
      15
      APR 21, 2022 | 5:30 AM
      Hypoxia Biomarkers: Personalizing Cancer Treatments by Targeting Hypoxia
      Hypoxia Biomarkers: Personalizing Cancer Treatments by Targeting...
      A hypoxic tumour microenvironment is a feature of solid tumours. Many tumour types contain high fractions of hypoxic tissue. The relationship between high levels of tumour hypoxia and a poor...
      Speaker: Joely Irlam
      Presented at: Genetics Week Virtual Event Series 2022
      2
      SEP 22, 2021 | 12:00 PM
      Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC® ONIX2 Microfluidic Platform
      Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC®...
      While providing indispensable insight into immune processes, the live cell imaging of immune cells poses unique challenges due to their non-adherent nature. Suspension cells such as immune c...
      Speaker: Jun Park, PhD
      Presented at: Cell Biology Virtual Event Series 2021
      Sponsored By: MilliporeSigma
      0
      SEP 23, 2020 | 3:00 PM
      Beyond the Culture Flask: How Membrane- and Microfluidic-based Platforms can create more Physiologically Relevant Tissue Culture Systems
      Beyond the Culture Flask: How Membrane- and Microfluidic-based...
      For more than a century, breakthroughs in biological sciences have relied on the ability to study cells outside of respective organisms. While majority of cell culturing is still performed u...
      Speaker: Jun Park, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      1
      JUN 03, 2020 | 2:00 PM
      Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC® ONIX2 Microfluidic Platform
      Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC®...
      While providing indispensable insight into immune processes, the live cell imaging of immune cells poses unique challenges due to their non-adherent nature. Suspension cells such as immune c...
      Speaker: Jun Park, PhD
      Presented at: Immuno-Oncology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      1
      OCT 29, 2019 | 7:00 AM
      Optimizing high-content screening tools for physiologically-relevant 3D in vitro models
      Optimizing high-content screening tools for physiologically-relevant...
      DATE: October 29, 2019TIME: 7:00am PDT3D cell culture systems have recently emerged as tools for reproducing the cellular environment and the organization of tissues/organs, where cel...
      Speaker: Elodie Vandenhaute , Zied Souguir , Daniel O'Connor
      Sponsored By: Molecular Devices
      8
      SEP 27, 2019 | 9:00 AM
      Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
      Investigating how Tpz-1 may be used as a novel therapeutic agent...
      DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
      Speaker: Jessica Hess
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      AUG 15, 2019 | 9:00 AM
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
      Speaker: Alexandra Taraboletti, PHD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      JUL 31, 2019 | 9:00 AM
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
      Speaker: Elizabeth Delery, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      MAY 08, 2019 | 6:00 AM
      C.E. CREDITS
      Novel DNA Methylation in Mammals
      Novel DNA Methylation in Mammals
      Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
      Speaker: Tao Wu, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      FEB 27, 2019 | 8:00 AM
      Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
      Prepare for success: GMP cell banks as part of a staged, standardized,...
      DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
      Speaker: Benjamin Fryer
      Sponsored By: Thermo Fisher Scientific/Gibco
      9
      NOV 28, 2018 | 7:00 AM
      Discover how single-cell RNA sequencing provides deeper insights into lung cancer biology
      Discover how single-cell RNA sequencing provides deeper insights...
      DATE: November 28, 2018TIME:  7:00AM PSTSingle-cell genomics enables a deep dive into the mechanisms responsible for health and disease, in areas from cancer biology to neurob...
      Speaker: Bernard Thienpont , Annika Branting , Pawel Zajac, Ph.D.
      Sponsored By: Illumina, 10x Genomics
      5
      APR 27, 2018 | 10:00 AM
      Investigating DNA repair mechanisms in hypoxic brain tumours and the link to treatment resistance
      Investigating DNA repair mechanisms in hypoxic brain tumours and...
      DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
      Speaker: Sophie Cowman
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 4
      NOV 14, 2017 | 10:00 AM
      WEBINAR:  Cancer Cells Send Signals Boosting Survival and Drug Resistance in Other Cancer Cells
      WEBINAR: Cancer Cells Send Signals Boosting Survival and Drug...
      DATE: November 14, 2017TIME: 10:00am PST, 1:00pm ESTSuccessful tumor outgrowth requires the coordination of a variety of cell intrinsic and cell extrinsic signaling events. These events...
      Speaker: Jeffrey Rodvold, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco, Thermo Fisher Scientific/Gibco
      5 5
      OCT 12, 2017 | 7:30 AM
      Keynote Presentation: Tumor Re-oxygenation - Basic and Therapeutic Considerations
      Keynote Presentation: Tumor Re-oxygenation - Basic and Therapeutic...
      The role played by inflammatory hypoxia in biology and treatment of solid tumors will be reviewed.  The opportunity to enhance all forms of current anti-tumor therapies through tumor re-...
      Speaker: George Perdrizet, MD, PhD, FACS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      JUL 01, 2017 | 12:00 AM
      Physiological Oxygen: Historical and Molecular Perspective for Stem Cell Culture
      Physiological Oxygen: Historical and Molecular Perspective for...
      For many decades, cell lines have been cultured in standard CO2 incubators at “normal” atmospheric oxygen concentrations of about 21%. But oxygen concentrations in the human or an...
      Speaker: Mary Kay Bates, M.S.
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      MAR 15, 2017 | 7:30 AM
      Exercise Targeting Neuroplasticity in Parkinson's disease
      Exercise Targeting Neuroplasticity in Parkinson's disease
      Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
      Speaker: Giselle Petzinger, MD
      Presented at: Neuroscience Virtual Event Series 2017
      2
      AUG 30, 2016 | 8:00 AM
      Transitioning to the clinic from proof of concept research: Challenges associated with converting research materials and methods to a clinical grade product
      Transitioning to the clinic from proof of concept research: Challenges...
      Years of significant effort can go into generating key proof of concept data to support moving bench research to clinical development.Yet, much work remains in order to transition from POC to...
      Speaker: Ben Fryer, PhD
      Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      SEP 30, 2015 | 9:00 AM
      Lactate-driven metabolic adaptation modulates breast cancer progression
      Lactate-driven metabolic adaptation modulates breast cancer progression
      The Warburg effect or aerobic glycolysis is a well-known cancer metabolism phenomenon and serves as an established test for tumor detection with FDG-PET scanning technology. Cancer cells swit...
      Speaker: Jennifer Molina, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      SEP 02, 2015 | 7:30 AM
      Keynote: The Science of Biofilm Control with Antimicrobial Agents
      Keynote: The Science of Biofilm Control with Antimicrobial Agents
      This presentation will discuss fundamental physical, chemical, and biological concepts important to understanding control of detrimental biofilms. Four phenomena that are important in the act...
      Speaker: Phil Stewart, PhD
      Presented at: Microbiology Virtual Event Series 2015
      3
      MAR 19, 2015 | 7:30 AM
      Keynote - The Environmental Causes of Schizophrenia - Developmental Hazards, Social Defeat, and Drug Abuse
      Keynote - The Environmental Causes of Schizophrenia - Developmental...
      Traditional psychiatric textbooks describe schizophrenia as a clinical enigma of unknown aetiology. However, this is no longer true. We now know a great deal about the risk factors, or contr...
      Speaker: Sir Robin Murray, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      13
      OCT 30, 2014 | 3:00 PM
      Probing cancer metabolism using isotope tracers to identify therapeutic targets
      Probing cancer metabolism using isotope tracers to identify therapeutic...
      Oncogenic mutations in isocitrate dehydrogenase 1 (IDH1) or 2 (IDH2) compromise their normal activity and induce NADPH-dependent (D)2-hydroxyglutarate (2HG) production within the cytosol or m...
      Speaker: Christian Metallo, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 30, 2014 | 12:00 PM
      The metabolic microenvironment in tumors and its impact on T-cell mediated immunity
      The metabolic microenvironment in tumors and its impact on T-cell...
      It has become widely accepted that the presence of intraepithelial CD8+ T cell correlate with improved patient survival. In contrast, tumors largely devoid of immune infiltrations or infiltra...
      Speaker: Julian J. Lum, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      10
      FEB 06, 2014 | 7:00 AM
      C.E. CREDITS
      Pain perception: the scientific evidence, assessment and alleviation of pain in fish
      Pain perception: the scientific evidence, assessment and alleviation...
      The question of pain in fish has been subject to much debate and, since fish are a popular experimental model globally and commercially important in fisheries, recreational angling and aquac...
      Speaker: Lynne U Sneddon, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      12
    DEC 07, 2023 | 8:00 AM
    Translating COSMIC's gold standard data into actionable insights
    Translating COSMIC's gold standard data into actionable insights
    As the vast landscape of genetic oncology continues to expand, the ability to understand and utilize the full potential of this rich data becomes increasingly challenging. As a result, resea...
    Speaker: Leonie Hodges , Alex Holmes, Ph.D. , Jennifer Wilding, Ph.D.
    Sponsored By: QIAGEN
    15
    APR 21, 2022 | 5:30 AM
    Hypoxia Biomarkers: Personalizing Cancer Treatments by Targeting Hypoxia
    Hypoxia Biomarkers: Personalizing Cancer Treatments by Targeting...
    A hypoxic tumour microenvironment is a feature of solid tumours. Many tumour types contain high fractions of hypoxic tissue. The relationship between high levels of tumour hypoxia and a poor...
    Speaker: Joely Irlam
    Presented at: Genetics Week Virtual Event Series 2022
    2
    SEP 22, 2021 | 12:00 PM
    Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC® ONIX2 Microfluidic Platform
    Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC®...
    While providing indispensable insight into immune processes, the live cell imaging of immune cells poses unique challenges due to their non-adherent nature. Suspension cells such as immune c...
    Speaker: Jun Park, PhD
    Presented at: Cell Biology Virtual Event Series 2021
    Sponsored By: MilliporeSigma
    0
    SEP 23, 2020 | 3:00 PM
    Beyond the Culture Flask: How Membrane- and Microfluidic-based Platforms can create more Physiologically Relevant Tissue Culture Systems
    Beyond the Culture Flask: How Membrane- and Microfluidic-based...
    For more than a century, breakthroughs in biological sciences have relied on the ability to study cells outside of respective organisms. While majority of cell culturing is still performed u...
    Speaker: Jun Park, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    1
    JUN 03, 2020 | 2:00 PM
    Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC® ONIX2 Microfluidic Platform
    Dynamic Live Cell Imaging of Adherent and Immune Cells using CellASIC®...
    While providing indispensable insight into immune processes, the live cell imaging of immune cells poses unique challenges due to their non-adherent nature. Suspension cells such as immune c...
    Speaker: Jun Park, PhD
    Presented at: Immuno-Oncology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    1
     
     
  • OCT 29, 2019 | 7:00 AM
    Optimizing high-content screening tools for physiologically-relevant 3D in vitro models
    Optimizing high-content screening tools for physiologically-relevant...
    DATE: October 29, 2019TIME: 7:00am PDT3D cell culture systems have recently emerged as tools for reproducing the cellular environment and the organization of tissues/organs, where cel...
    Speaker: Elodie Vandenhaute , Zied Souguir , Daniel O'Connor
    Sponsored By: Molecular Devices
    8
    SEP 27, 2019 | 9:00 AM
    Investigating how Tpz-1 may be used as a novel therapeutic agent in the treatment of human hematologic cancers
    Investigating how Tpz-1 may be used as a novel therapeutic agent...
    DATE: September 27, 2019TIME: 9:00am PT, 12:00pm ET Thienopyrazole derivatives have recently emerged as effective antitumoral agents with kinase inhibitory activity. In this s...
    Speaker: Jessica Hess
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
    AUG 15, 2019 | 9:00 AM
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
    Speaker: Alexandra Taraboletti, PHD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    JUL 31, 2019 | 9:00 AM
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
    Speaker: Elizabeth Delery, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
    MAY 08, 2019 | 6:00 AM
    C.E. CREDITS
    Novel DNA Methylation in Mammals
    Novel DNA Methylation in Mammals
    Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
    Speaker: Tao Wu, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
     
     
  • FEB 27, 2019 | 8:00 AM
    Prepare for success: GMP cell banks as part of a staged, standardized, platform-style cell production process
    Prepare for success: GMP cell banks as part of a staged, standardized,...
    DATE:  February 27, 2019TIME:  8:00am PST Pluripotent stem cells (PSCs) can form any tissue or cell in the body, and are the ideal starting material to manufacture...
    Speaker: Benjamin Fryer
    Sponsored By: Thermo Fisher Scientific/Gibco
    9
    NOV 28, 2018 | 7:00 AM
    Discover how single-cell RNA sequencing provides deeper insights into lung cancer biology
    Discover how single-cell RNA sequencing provides deeper insights...
    DATE: November 28, 2018TIME:  7:00AM PSTSingle-cell genomics enables a deep dive into the mechanisms responsible for health and disease, in areas from cancer biology to neurob...
    Speaker: Bernard Thienpont , Annika Branting , Pawel Zajac, Ph.D.
    Sponsored By: Illumina, 10x Genomics
    5
    APR 27, 2018 | 10:00 AM
    Investigating DNA repair mechanisms in hypoxic brain tumours and the link to treatment resistance
    Investigating DNA repair mechanisms in hypoxic brain tumours and...
    DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
    Speaker: Sophie Cowman
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 4
    NOV 14, 2017 | 10:00 AM
    WEBINAR:  Cancer Cells Send Signals Boosting Survival and Drug Resistance in Other Cancer Cells
    WEBINAR: Cancer Cells Send Signals Boosting Survival and Drug...
    DATE: November 14, 2017TIME: 10:00am PST, 1:00pm ESTSuccessful tumor outgrowth requires the coordination of a variety of cell intrinsic and cell extrinsic signaling events. These events...
    Speaker: Jeffrey Rodvold, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco, Thermo Fisher Scientific/Gibco
    5 5
    OCT 12, 2017 | 7:30 AM
    Keynote Presentation: Tumor Re-oxygenation - Basic and Therapeutic Considerations
    Keynote Presentation: Tumor Re-oxygenation - Basic and Therapeutic...
    The role played by inflammatory hypoxia in biology and treatment of solid tumors will be reviewed.  The opportunity to enhance all forms of current anti-tumor therapies through tumor re-...
    Speaker: George Perdrizet, MD, PhD, FACS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
     
     
  • JUL 01, 2017 | 12:00 AM
    Physiological Oxygen: Historical and Molecular Perspective for Stem Cell Culture
    Physiological Oxygen: Historical and Molecular Perspective for...
    For many decades, cell lines have been cultured in standard CO2 incubators at “normal” atmospheric oxygen concentrations of about 21%. But oxygen concentrations in the human or an...
    Speaker: Mary Kay Bates, M.S.
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    MAR 15, 2017 | 7:30 AM
    Exercise Targeting Neuroplasticity in Parkinson's disease
    Exercise Targeting Neuroplasticity in Parkinson's disease
    Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
    Speaker: Giselle Petzinger, MD
    Presented at: Neuroscience Virtual Event Series 2017
    2
    AUG 30, 2016 | 8:00 AM
    Transitioning to the clinic from proof of concept research: Challenges associated with converting research materials and methods to a clinical grade product
    Transitioning to the clinic from proof of concept research: Challenges...
    Years of significant effort can go into generating key proof of concept data to support moving bench research to clinical development.Yet, much work remains in order to transition from POC to...
    Speaker: Ben Fryer, PhD
    Presented at: 4th Annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    SEP 30, 2015 | 9:00 AM
    Lactate-driven metabolic adaptation modulates breast cancer progression
    Lactate-driven metabolic adaptation modulates breast cancer progression
    The Warburg effect or aerobic glycolysis is a well-known cancer metabolism phenomenon and serves as an established test for tumor detection with FDG-PET scanning technology. Cancer cells swit...
    Speaker: Jennifer Molina, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
    SEP 02, 2015 | 7:30 AM
    Keynote: The Science of Biofilm Control with Antimicrobial Agents
    Keynote: The Science of Biofilm Control with Antimicrobial Agents
    This presentation will discuss fundamental physical, chemical, and biological concepts important to understanding control of detrimental biofilms. Four phenomena that are important in the act...
    Speaker: Phil Stewart, PhD
    Presented at: Microbiology Virtual Event Series 2015
    3
     
     
  • MAR 19, 2015 | 7:30 AM
    Keynote - The Environmental Causes of Schizophrenia - Developmental Hazards, Social Defeat, and Drug Abuse
    Keynote - The Environmental Causes of Schizophrenia - Developmental...
    Traditional psychiatric textbooks describe schizophrenia as a clinical enigma of unknown aetiology. However, this is no longer true. We now know a great deal about the risk factors, or contr...
    Speaker: Sir Robin Murray, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    13
    OCT 30, 2014 | 3:00 PM
    Probing cancer metabolism using isotope tracers to identify therapeutic targets
    Probing cancer metabolism using isotope tracers to identify therapeutic...
    Oncogenic mutations in isocitrate dehydrogenase 1 (IDH1) or 2 (IDH2) compromise their normal activity and induce NADPH-dependent (D)2-hydroxyglutarate (2HG) production within the cytosol or m...
    Speaker: Christian Metallo, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 30, 2014 | 12:00 PM
    The metabolic microenvironment in tumors and its impact on T-cell mediated immunity
    The metabolic microenvironment in tumors and its impact on T-cell...
    It has become widely accepted that the presence of intraepithelial CD8+ T cell correlate with improved patient survival. In contrast, tumors largely devoid of immune infiltrations or infiltra...
    Speaker: Julian J. Lum, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    10
    FEB 06, 2014 | 7:00 AM
    C.E. CREDITS
    Pain perception: the scientific evidence, assessment and alleviation of pain in fish
    Pain perception: the scientific evidence, assessment and alleviation...
    The question of pain in fish has been subject to much debate and, since fish are a popular experimental model globally and commercially important in fisheries, recreational angling and aquac...
    Speaker: Lynne U Sneddon, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    12
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