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    Mechanism of Action

    Mechanism of action refers to the specific biological process through which the drug treats the underlying cause. It describes the more general response or effect of the drug. It is the interaction that allows a drug substance to produce it pharmacological effect.

    Webinars

    • JUN 17, 2025 | 8:00 AM
      From Insight to Impact: A Conversation on the Strategic Role of Biomarkers in Drug Discovery and Clinical Trials
      From Insight to Impact: A Conversation on the Strategic Role of...
      Biomarkers are no longer just exploratory tools-they're becoming strategic assets in drug development and clinical trials. Join a panel of industry thought leaders as they explore how biomar...
      Speaker: Dawn Waterworth , Magnus Althage , Jen-Chieh Chuang , Ray Chen
      Sponsored By: Olink Proteomics
      12
      MAY 15, 2025 | 8:00 AM
      Recent advances in covalent and non-covalent drug discovery with TMT quantitative chemoproteomics
      Recent advances in covalent and non-covalent drug discovery with...
      Join us for an in-depth webinar on quantitative chemoproteomics with TMT reagents, featuring two distinguished speakers from both academia and industry. This webinar aims to bridge the gap b...
      Speaker: Qing Yu, Ph.D. , Alexey Chernobrovkin, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      12
      APR 08, 2025 | 8:00 AM
      Probing cell surface target internalization in cancer and immunology
      Probing cell surface target internalization in cancer and immunology
      Fluorescence imaging offers robust, multi-parametric and scalable analysis of celllevel activity in heterogenous populations with excellent spatial and temporal resolution. This seminar will...
      Speaker: Dan Beacham, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      14
      MAR 12, 2025 | 8:00 AM
      Revolutionize Protein Quantitation With Leo - A High-Throughput, Fully Automated Simple Western System That Provides Results in as Little as 3 Hours.
      Revolutionize Protein Quantitation With Leo - A High-Throughput,...
      Bio-Techne is proud to provide a first glimpse into the power and performance of the Leo™ System using several assay models as it hits the market. Data highlights include throughput, s...
      Speaker: Jessica Dermody, PhD , Chris Heger, PhD
      Presented at: The Simple Way to Protein Research
      5 1
      NOV 14, 2024 | 12:00 PM
      Mitigating ADC Toxicities With Linker-Payload Design
      Mitigating ADC Toxicities With Linker-Payload Design
      Antibody-drug conjugates (ADCs) represent the most successful class of active targeting drug-delivery systems, however, despite the increasing number of FDA approvals treatment-related adver...
      Speaker: Matthew Giese, M.S.
      Sponsored By: Vector Laboratories
      10
      OCT 16, 2024 | 10:30 AM
      C.E. CREDITS
      Design and Evaluation of a Multiplexed Assay to Assess Human Immunogenicity Against Humira®
      Design and Evaluation of a Multiplexed Assay to Assess Human Immunogenicity...
      The use of biologic-based therapeutics has revolutionized our ability to treat complex diseases such as cancer- and autoimmune-related disorders. Biologic-based therapeutics are known to gen...
      Speaker: Paul Rhyne, PhD
      Presented at: Cell & Gene Therapy Virtual Event Series 2024
      Sponsored By: Luminex - A DiaSorin Company
      5
      MAY 29, 2024 | 9:00 AM
      C.E. CREDITS
      HISTOLOGY HACKS FOR CRYOSECTIONING
      HISTOLOGY HACKS FOR CRYOSECTIONING
      Histology laboratorians in the research world move fast, but those who perform cryosectioning know that these particular tissues require lighting speed and precision. Cryosectioning is the a...
      Speaker: Marla Rivera-Oliver, PhD
      Sponsored By: Leica Biosystems
      20 1
      APR 17, 2024 | 12:00 PM
      C.E. CREDITS
      Keynote Presentation: Utilizing Psychedelics and Neuroplasticity as an Integrative Approach to Pain Management
      Keynote Presentation: Utilizing Psychedelics and Neuroplasticity...
      Currently we have a chronic pain and mental health epidemic with excessive prescriptions for ssri benzos and opioids. People are unable to feel and process pain. Chronic stress can lead to c...
      Speaker: Michelle Weiner, DO, MPH
      Presented at: Cannabis Sciences Virtual Event Series 2024
      2
      FEB 14, 2024 | 9:00 AM
      C.E. CREDITS
      HISTOLOGY HACKS FOR CRYOSECTIONING
      HISTOLOGY HACKS FOR CRYOSECTIONING
      Learning Objectives Identify three ways automation improves cryosectioning techniques Demonstrate three essential elements to obtaining reproducible, high-quality sections with cryosectionin...
      Speaker: Marla Rivera-Oliver, PhD
      Sponsored By: Leica Biosystems
      30 1
      JAN 23, 2024 | 10:00 AM
      Exploring the Potential of 3D Organoids through Live-Cell Analysis
      Exploring the Potential of 3D Organoids through Live-Cell Analysis
      Organoid technologies are increasingly being used as in vitro models of human development and disease because they exhibit morphogenetic, structural and functional properties that recapitula...
      Speaker: Kalpana Barnes
      Presented at: The Future of Biomedicine: Reproducible Advanced Cell Systems and Translational Insights
      2
      DEC 07, 2023 | 8:00 AM
      Translating COSMIC's gold standard data into actionable insights
      Translating COSMIC's gold standard data into actionable insights
      As the vast landscape of genetic oncology continues to expand, the ability to understand and utilize the full potential of this rich data becomes increasingly challenging. As a result, resea...
      Speaker: Leonie Hodges , Alex Holmes, Ph.D. , Jennifer Wilding, Ph.D.
      Sponsored By: QIAGEN
      15
      JUL 26, 2023 | 12:15 PM
      Advancing Protein Stabilization Therapeutic Development and DUBTAC Drug Discovery through Gene and Cell Engineering
      Advancing Protein Stabilization Therapeutic Development and DUBTAC...
      Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
      Speaker: Dr. Yongli Shan
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      JUN 06, 2023 | 9:00 AM
      Time-resolved electron microscopy: synaptic ultrastructure millisecond by millisecond with high-pressure freezing
      Time-resolved electron microscopy: synaptic ultrastructure millisecond...
      Transmission electron microscopy reveals the architecture of cells at nanometer resolution, but chemical fixation severely warps their native structure. The true ultrastructure of cells can...
      Speaker: Shigeki Watanabe, Ph.D , Grant Kusick
      Sponsored By: Leica Microsystems
      8
      APR 05, 2023 | 1:00 PM
      Practical considerations for fluorescent cell staining and microscopy in cancer cell biology research
      Practical considerations for fluorescent cell staining and microscopy...
      Date: April 04, 2023 Time: 10:00pm (PDT), Date: April 05, 2023 Time: 2:00am (EDT), 7:00am (CEST), 1:00pm (SGT) This seminar provides an overview of fluorescence microscopy in cancer research...
      Speaker: Dan Beacham, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      27
      MAR 08, 2023 | 6:00 AM
      Recurrent Neural Networks in Brains and Machines
      Recurrent Neural Networks in Brains and Machines
      Neural networks are a powerful tool for modeling neural activity in the brain. In this talk, I will discuss how these models have helped in my own research and highlight recent work building...
      Speaker: Christopher Cueva, PhD
      Presented at: Neuroscience Virtual Event Series 2023
      2
      FEB 22, 2023 | 5:30 AM
      Bridging the Gap - How Human Microphysiological Systems Improve the Translatability of NASH Drug Discovery
      Bridging the Gap - How Human Microphysiological Systems Improve...
      Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...
      Speaker: Raul Silva
      Presented at: Drug Discovery & Development Virtual Event Series 2023
      2
      FEB 15, 2023 | 7:00 AM
      Scattering Microscopy: Label-Free Imaging Approaches
      Scattering Microscopy: Label-Free Imaging Approaches
      Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
      Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
      Sponsored By: Teledyne Photometrics
      28
      APR 19, 2022 | 5:30 AM
      C.E. CREDITS
      Advances in High Throughput Proteomics using Next Generation Sequencing as a Readout
      Advances in High Throughput Proteomics using Next Generation Sequencing...
      The combination of the wealth of genomic and phenotypic datasets to the measurement of the circulating proteome enables a snapshot of real-time biology and important results for determining...
      Speaker: Dale Yuzuki, M.A., M.Ed.
      Presented at: Genetics Week Virtual Event Series 2022
      3
      APR 05, 2022 | 8:00 AM
      Investigating antimicrobial mechanisms-of-action using automated genome-wide and gene-specific editing
      Investigating antimicrobial mechanisms-of-action using automated...
      Date: April 05, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEDT) Members of the cinnamic acid and stilbenoid chemical families are common intermediates in the production of important bi...
      Speaker: Ali Clark-ElSayed
      Sponsored By: Inscripta
      8
      MAR 23, 2022 | 11:55 PM
      Overcoming Challenges Associated with Analysis of Pesticides Regulated by Colorado State in Hemp Using a Novel LC/MS/MS Method with Dual ESI and APCI Source
      Overcoming Challenges Associated with Analysis of Pesticides Regulated...
      Like any other agricultural crop, pesticides are applied to hemp plants to protect it from pests and improve growth yield. Chronic exposure to pesticides can lead to serious health risks and...
      Speaker: Avinash Dalmia, PhD
      Presented at: Cannabis Sciences Virtual Event Series 2022
      2
      MAR 10, 2022 | 11:55 PM
      The Spatial Reach of Brain Wave Synchronization
      The Spatial Reach of Brain Wave Synchronization
      Brain wave synchronization, also called neuronal coherence, is a fundamental mechanism of communication in the brain, where synchronized field potentials coordinate synaptic and spiking even...
      Speaker: John Myers, PhD
      Presented at: Neuroscience Virtual Event Series 2022
      2
      MAR 09, 2022 | 10:00 AM
      Time-resolved electron microscopy: synaptic ultrastructure millisecond by millisecond with high-pressure freezing
      Time-resolved electron microscopy: synaptic ultrastructure millisecond...
      Date: March 09, 2022 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CEST) Transmission electron microscopy reveals the architecture of cells at nanometer resolution, but chemical fixation severe...
      Speaker: Shigeki Watanabe, Ph.D , Grant Kusick
      Sponsored By: Leica Microsystems
      5
      MAR 01, 2022 | 8:00 AM
      Histology Hacks For Cryosectioning
      Histology Hacks For Cryosectioning
      Date: March 01, 2022 Time: 08:00am (PST), 11:00am (EST) Histology laboratorians in the research world move fast, but those who perform cryosectioning know that these particular tissues requi...
      Speaker: Marla Rivera-Oliver, PhD
      Sponsored By: Leica Biosystems
      22
      AUG 25, 2021 | 12:00 AM
      The Long Hangover: Adolescent Intermittent Ethanol's Effects on Hippocampal Neuroimmune and Cell Death Markers, Reversal by Donepezil
      The Long Hangover: Adolescent Intermittent Ethanol's Effects on...
      Adolescence is a critical period for the developing brain, and binge drinking during this neuromaturation can result in enduring abnormal brain function and behavior. Repeated adolescent bin...
      Speaker: Kati Healey, MA, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      1
    JUN 17, 2025 | 8:00 AM
    From Insight to Impact: A Conversation on the Strategic Role of Biomarkers in Drug Discovery and Clinical Trials
    From Insight to Impact: A Conversation on the Strategic Role of...
    Biomarkers are no longer just exploratory tools-they're becoming strategic assets in drug development and clinical trials. Join a panel of industry thought leaders as they explore how biomar...
    Speaker: Dawn Waterworth , Magnus Althage , Jen-Chieh Chuang , Ray Chen
    Sponsored By: Olink Proteomics
    12
    MAY 15, 2025 | 8:00 AM
    Recent advances in covalent and non-covalent drug discovery with TMT quantitative chemoproteomics
    Recent advances in covalent and non-covalent drug discovery with...
    Join us for an in-depth webinar on quantitative chemoproteomics with TMT reagents, featuring two distinguished speakers from both academia and industry. This webinar aims to bridge the gap b...
    Speaker: Qing Yu, Ph.D. , Alexey Chernobrovkin, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    12
    APR 08, 2025 | 8:00 AM
    Probing cell surface target internalization in cancer and immunology
    Probing cell surface target internalization in cancer and immunology
    Fluorescence imaging offers robust, multi-parametric and scalable analysis of celllevel activity in heterogenous populations with excellent spatial and temporal resolution. This seminar will...
    Speaker: Dan Beacham, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    14
    MAR 12, 2025 | 8:00 AM
    Revolutionize Protein Quantitation With Leo - A High-Throughput, Fully Automated Simple Western System That Provides Results in as Little as 3 Hours.
    Revolutionize Protein Quantitation With Leo - A High-Throughput,...
    Bio-Techne is proud to provide a first glimpse into the power and performance of the Leo™ System using several assay models as it hits the market. Data highlights include throughput, s...
    Speaker: Jessica Dermody, PhD , Chris Heger, PhD
    Presented at: The Simple Way to Protein Research
    5 1
    NOV 14, 2024 | 12:00 PM
    Mitigating ADC Toxicities With Linker-Payload Design
    Mitigating ADC Toxicities With Linker-Payload Design
    Antibody-drug conjugates (ADCs) represent the most successful class of active targeting drug-delivery systems, however, despite the increasing number of FDA approvals treatment-related adver...
    Speaker: Matthew Giese, M.S.
    Sponsored By: Vector Laboratories
    10
     
     
  • OCT 16, 2024 | 10:30 AM
    C.E. CREDITS
    Design and Evaluation of a Multiplexed Assay to Assess Human Immunogenicity Against Humira®
    Design and Evaluation of a Multiplexed Assay to Assess Human Immunogenicity...
    The use of biologic-based therapeutics has revolutionized our ability to treat complex diseases such as cancer- and autoimmune-related disorders. Biologic-based therapeutics are known to gen...
    Speaker: Paul Rhyne, PhD
    Presented at: Cell & Gene Therapy Virtual Event Series 2024
    Sponsored By: Luminex - A DiaSorin Company
    5
    MAY 29, 2024 | 9:00 AM
    C.E. CREDITS
    HISTOLOGY HACKS FOR CRYOSECTIONING
    HISTOLOGY HACKS FOR CRYOSECTIONING
    Histology laboratorians in the research world move fast, but those who perform cryosectioning know that these particular tissues require lighting speed and precision. Cryosectioning is the a...
    Speaker: Marla Rivera-Oliver, PhD
    Sponsored By: Leica Biosystems
    20 1
    APR 17, 2024 | 12:00 PM
    C.E. CREDITS
    Keynote Presentation: Utilizing Psychedelics and Neuroplasticity as an Integrative Approach to Pain Management
    Keynote Presentation: Utilizing Psychedelics and Neuroplasticity...
    Currently we have a chronic pain and mental health epidemic with excessive prescriptions for ssri benzos and opioids. People are unable to feel and process pain. Chronic stress can lead to c...
    Speaker: Michelle Weiner, DO, MPH
    Presented at: Cannabis Sciences Virtual Event Series 2024
    2
    FEB 14, 2024 | 9:00 AM
    C.E. CREDITS
    HISTOLOGY HACKS FOR CRYOSECTIONING
    HISTOLOGY HACKS FOR CRYOSECTIONING
    Learning Objectives Identify three ways automation improves cryosectioning techniques Demonstrate three essential elements to obtaining reproducible, high-quality sections with cryosectionin...
    Speaker: Marla Rivera-Oliver, PhD
    Sponsored By: Leica Biosystems
    30 1
    JAN 23, 2024 | 10:00 AM
    Exploring the Potential of 3D Organoids through Live-Cell Analysis
    Exploring the Potential of 3D Organoids through Live-Cell Analysis
    Organoid technologies are increasingly being used as in vitro models of human development and disease because they exhibit morphogenetic, structural and functional properties that recapitula...
    Speaker: Kalpana Barnes
    Presented at: The Future of Biomedicine: Reproducible Advanced Cell Systems and Translational Insights
    2
     
     
  • DEC 07, 2023 | 8:00 AM
    Translating COSMIC's gold standard data into actionable insights
    Translating COSMIC's gold standard data into actionable insights
    As the vast landscape of genetic oncology continues to expand, the ability to understand and utilize the full potential of this rich data becomes increasingly challenging. As a result, resea...
    Speaker: Leonie Hodges , Alex Holmes, Ph.D. , Jennifer Wilding, Ph.D.
    Sponsored By: QIAGEN
    15
    JUL 26, 2023 | 12:15 PM
    Advancing Protein Stabilization Therapeutic Development and DUBTAC Drug Discovery through Gene and Cell Engineering
    Advancing Protein Stabilization Therapeutic Development and DUBTAC...
    Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
    Speaker: Dr. Yongli Shan
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
    JUN 06, 2023 | 9:00 AM
    Time-resolved electron microscopy: synaptic ultrastructure millisecond by millisecond with high-pressure freezing
    Time-resolved electron microscopy: synaptic ultrastructure millisecond...
    Transmission electron microscopy reveals the architecture of cells at nanometer resolution, but chemical fixation severely warps their native structure. The true ultrastructure of cells can...
    Speaker: Shigeki Watanabe, Ph.D , Grant Kusick
    Sponsored By: Leica Microsystems
    8
    APR 05, 2023 | 1:00 PM
    Practical considerations for fluorescent cell staining and microscopy in cancer cell biology research
    Practical considerations for fluorescent cell staining and microscopy...
    Date: April 04, 2023 Time: 10:00pm (PDT), Date: April 05, 2023 Time: 2:00am (EDT), 7:00am (CEST), 1:00pm (SGT) This seminar provides an overview of fluorescence microscopy in cancer research...
    Speaker: Dan Beacham, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    27
    MAR 08, 2023 | 6:00 AM
    Recurrent Neural Networks in Brains and Machines
    Recurrent Neural Networks in Brains and Machines
    Neural networks are a powerful tool for modeling neural activity in the brain. In this talk, I will discuss how these models have helped in my own research and highlight recent work building...
    Speaker: Christopher Cueva, PhD
    Presented at: Neuroscience Virtual Event Series 2023
    2
     
     
  • FEB 22, 2023 | 5:30 AM
    Bridging the Gap - How Human Microphysiological Systems Improve the Translatability of NASH Drug Discovery
    Bridging the Gap - How Human Microphysiological Systems Improve...
    Non-alcoholic fatty liver disease (NAFLD) is a spectrum of metabolic disorders affecting 25% of our global population. 20% of NAFLD patients go on to develop Non-alcoholic steatohepatitis (N...
    Speaker: Raul Silva
    Presented at: Drug Discovery & Development Virtual Event Series 2023
    2
    FEB 15, 2023 | 7:00 AM
    Scattering Microscopy: Label-Free Imaging Approaches
    Scattering Microscopy: Label-Free Imaging Approaches
    Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
    Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
    Sponsored By: Teledyne Photometrics
    28
    APR 19, 2022 | 5:30 AM
    C.E. CREDITS
    Advances in High Throughput Proteomics using Next Generation Sequencing as a Readout
    Advances in High Throughput Proteomics using Next Generation Sequencing...
    The combination of the wealth of genomic and phenotypic datasets to the measurement of the circulating proteome enables a snapshot of real-time biology and important results for determining...
    Speaker: Dale Yuzuki, M.A., M.Ed.
    Presented at: Genetics Week Virtual Event Series 2022
    3
    APR 05, 2022 | 8:00 AM
    Investigating antimicrobial mechanisms-of-action using automated genome-wide and gene-specific editing
    Investigating antimicrobial mechanisms-of-action using automated...
    Date: April 05, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEDT) Members of the cinnamic acid and stilbenoid chemical families are common intermediates in the production of important bi...
    Speaker: Ali Clark-ElSayed
    Sponsored By: Inscripta
    8
    MAR 23, 2022 | 11:55 PM
    Overcoming Challenges Associated with Analysis of Pesticides Regulated by Colorado State in Hemp Using a Novel LC/MS/MS Method with Dual ESI and APCI Source
    Overcoming Challenges Associated with Analysis of Pesticides Regulated...
    Like any other agricultural crop, pesticides are applied to hemp plants to protect it from pests and improve growth yield. Chronic exposure to pesticides can lead to serious health risks and...
    Speaker: Avinash Dalmia, PhD
    Presented at: Cannabis Sciences Virtual Event Series 2022
    2
     
     
  • MAR 10, 2022 | 11:55 PM
    The Spatial Reach of Brain Wave Synchronization
    The Spatial Reach of Brain Wave Synchronization
    Brain wave synchronization, also called neuronal coherence, is a fundamental mechanism of communication in the brain, where synchronized field potentials coordinate synaptic and spiking even...
    Speaker: John Myers, PhD
    Presented at: Neuroscience Virtual Event Series 2022
    2
    MAR 09, 2022 | 10:00 AM
    Time-resolved electron microscopy: synaptic ultrastructure millisecond by millisecond with high-pressure freezing
    Time-resolved electron microscopy: synaptic ultrastructure millisecond...
    Date: March 09, 2022 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CEST) Transmission electron microscopy reveals the architecture of cells at nanometer resolution, but chemical fixation severe...
    Speaker: Shigeki Watanabe, Ph.D , Grant Kusick
    Sponsored By: Leica Microsystems
    5
    MAR 01, 2022 | 8:00 AM
    Histology Hacks For Cryosectioning
    Histology Hacks For Cryosectioning
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    Speaker: Marla Rivera-Oliver, PhD
    Sponsored By: Leica Biosystems
    22
    AUG 25, 2021 | 12:00 AM
    The Long Hangover: Adolescent Intermittent Ethanol's Effects on Hippocampal Neuroimmune and Cell Death Markers, Reversal by Donepezil
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    Speaker: Kati Healey, MA, PhD
    Presented at: Neuroscience Virtual Event Series 2021
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