Mechanism of action refers to the specific biological process through which the drug treats the underlying cause. It describes the more general response or effect of the drug. It is the interaction that allows a drug substance to produce it pharmacological effect.
Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
The locomotion of humans and other animals requires a seamless flow of information from sensory modalities all the way to the motor periphery. As such, locomotion is an excellent system for...
Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
Normal behavior in any moving animal, including humans, relies on communication between motor systems that control movements, and the sensory systems we use to guide these actions. A critica...
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in developed countries, and it affects over 25% of the population worldwide. Within the next five y...
Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
DATE: October 2, 2019TIME: 9:00am PTThe Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Recently, Mol...
DNA profiling tools to teach undergraduate students about forensics generally utilize the PV92 Alu and D1S80 VNTR markers, but are both limited in scope. In contrast, advanced profiling syste...
Contemporary law enforcement has greatly expanded its ability to solve crimes by the adoption of advanced forensic techniques, electronic monitoring and new approaches in crime scene procedur...
The incidence of conditions such as diabetes, obesity, asthma, and cancer have increased substantially in the past 30 years. The human genome has not changed in that period of time, so the en...
Prediction of human response to chemical exposures is the primary challenge of pharmaceutical and environmental toxicology research. The complexity of human responses to xenobiotic exposures...
The practice of precision medicine utilizes advanced diagnostic tools to identify specific groups of patients on the basis of particular molecular characteristics, and guide their treatment w...
Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
The NIH put Precision Medicine on the map as a revolutionary way to manage disease, delivering the right treatment, to the right patient, at the right time. But what does Precision Medicine r...
Most cancer therapies have highly variable activity from one patient to another, with only a fraction of patients’ cancers responding to a given treatment. In many types of cancer, comb...
DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
Next-generation transcriptome and miRNome sequencing are routinely performed on traditional cell or tissue samples, as well as more difficult samples such as FFPE samples and biofluids. Regar...
The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
The locomotion of humans and other animals requires a seamless flow of information from sensory modalities all the way to the motor periphery. As such, locomotion is an excellent system for...
Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
Striatal neuromodulation through G-protein-coupled receptors (GPCRs) regulates complex voluntary motor actions, involving decision-making, learning, and action selection. The dorsal striatum...
Normal behavior in any moving animal, including humans, relies on communication between motor systems that control movements, and the sensory systems we use to guide these actions. A critica...
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in developed countries, and it affects over 25% of the population worldwide. Within the next five y...
Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
DATE: October 2, 2019TIME: 9:00am PTThe Clampfit software module is a useful tool to manipulate and analyze electrophysiological data acquired by pCLAMP™ software. Recently, Mol...
DNA profiling tools to teach undergraduate students about forensics generally utilize the PV92 Alu and D1S80 VNTR markers, but are both limited in scope. In contrast, advanced profiling syste...
Contemporary law enforcement has greatly expanded its ability to solve crimes by the adoption of advanced forensic techniques, electronic monitoring and new approaches in crime scene procedur...
The incidence of conditions such as diabetes, obesity, asthma, and cancer have increased substantially in the past 30 years. The human genome has not changed in that period of time, so the en...
Prediction of human response to chemical exposures is the primary challenge of pharmaceutical and environmental toxicology research. The complexity of human responses to xenobiotic exposures...
The practice of precision medicine utilizes advanced diagnostic tools to identify specific groups of patients on the basis of particular molecular characteristics, and guide their treatment w...
Tumor mutational burden (TMB) is an emerging biomarker that correlates with response to immunotherapeutic agents, such as checkpoint inhibitors. Recent studies indicate that a high mutation l...
The NIH put Precision Medicine on the map as a revolutionary way to manage disease, delivering the right treatment, to the right patient, at the right time. But what does Precision Medicine r...
Most cancer therapies have highly variable activity from one patient to another, with only a fraction of patients’ cancers responding to a given treatment. In many types of cancer, comb...
DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
Next-generation transcriptome and miRNome sequencing are routinely performed on traditional cell or tissue samples, as well as more difficult samples such as FFPE samples and biofluids. Regar...
The last two decades have seen an explosion in the volume of oncology data generated using next-generation sequencing (NGS) and multi-omics techniques. As a result, there is a growing need fo...
Whole food plant-based diets and medical cannabis have shared and continues to share similar levels of scrutiny, doubt, and stigma by the traditional medical community. One reason for the med...
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