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    Method optimization

    In medical research, method optimization evaluates ways to minimize or maximize specific parameters of a study. Optimization can involve parameters such as reducing the costs associated with a procedure, limiting the materials required to develop an assay, or obtaining maximal productivity from a technique.

    Webinars

    • OCT 21, 2020 | 12:00 AM
      Overcoming Challenges Analyzing Heavy Metals in Cannabis by ICP-MS
      Overcoming Challenges Analyzing Heavy Metals in Cannabis by ICP-MS
      There are many obstacles to overcome when analyzing Heavy Metals in Cannabis by ICPMS. Cannabis matrices can be difficult to prepare and analyze due to the complex components of products tha...
      Speaker: Shianna Hines
      Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
      1
      OCT 14, 2020 | 10:00 AM
      Strategies to Optimize Drug Testing:  What's In Your Panel and What Are You Missing?
      Strategies to Optimize Drug Testing: What's In Your Panel and...
      DATE: October 14, 2020 TIME: 10:00am PT Do you need help in planning your drug testing protocols? Did you know that a “one size fits all” approach to drug testing does not apply...
      Speaker: Jaime Noguez, Ph.D
      Sponsored By: Thermo Fisher Scientific
      15
      SEP 30, 2020 | 6:00 AM
      Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
      Enhancing efficiency and specificity with improved CRISPR components...
      Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
      Speaker: Ashley Jacobi
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: IDT
      2
      SEP 30, 2020 | 12:00 AM
      CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
      CRISPR/Cas9 as a tool to model and study cancer - insights and...
      Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
      Speaker: Grace R. Anderson, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 30, 2020 | 12:00 AM
      Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for Targeted Sequencing
      Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for...
      CRISPR experiments are a powerful tool which are easy to carry out, however it is more difficult to determine the outcome of these experiments, and to ensure that only the desired targets we...
      Speaker: Jonas Korlach, PhD
      Presented at: CRISPR Virtual Event Series 2020
      1
      SEP 29, 2020 | 8:00 AM
      Microbial Quality Control in Manufacturing of Medicinal Products
      Microbial Quality Control in Manufacturing of Medicinal Products
      DATE: September 29, 2020 TIME: 8:00 am PDT There is a steady increase in FDA 483s related to microbiology. Though most are for sterile products, non-sterile and terminally sterilized product...
      Speaker: Ziva Abraham
      Sponsored By: Sartorius
      19 5
      SEP 23, 2020 | 4:30 PM
      Anatomy of a nucleic acid sample preparation
      Anatomy of a nucleic acid sample preparation
      There are many methods of nucleic acid isolation. Each technology offers different approaches of purification of the template. However, it is important to control carry over of “proces...
      Speaker: Katherine Mechling
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2 1
      SEP 23, 2020 | 1:30 PM
      Analytic Options for Mass Cytometry Data
      Analytic Options for Mass Cytometry Data
      From data to insight: Explore the full potential of high dimensional data by leveraging machine learning algorithms 1:30–2:00 pm PDT Presented By: Qianjun Zhang, MS Utilizing FCS Expre...
      Speaker: Qianjun Zhang, MS , Sean Burke, MS , Thiru Selvanantham, PhD , Beth Lindroth Hill, PhD , Jared K. Burks, PhD , Trevor McKee, PhD , Donald Allen, BS
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 23, 2020 | 2:30 PM
      Sponsor-led Round Table Discussion: Vapor Tech: Making the Switch to Ceramics
      Sponsor-led Round Table Discussion: Vapor Tech: Making the Switch...
      One of the most prevalent consumption methods in the industry has been oils utilizing 510 thread cartridges. Over the last decade, consumers and manufacturers in this realm have refocused fr...
      Speaker: Moderator: Daniel Hwang
      Presented at: MJ Unpacked - Midwest
      1
      SEP 23, 2020 | 7:30 AM
      Cell Culture Troubleshooting Tips and Tricks
      Cell Culture Troubleshooting Tips and Tricks
      Cell culture continues to be a critical tool for most life science research and applications. From HeLa to iPSCs and 3D to organoids, culture methods have become more advanced and techniques...
      Speaker: Marina Wiklander, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      6
      SEP 22, 2020 | 9:15 AM
      Optimizing Glycan Separations and Analysis by HPLC
      Optimizing Glycan Separations and Analysis by HPLC
      This talk will explore HILIC chromatography methods for the analysis of released N-glycans labeled with InstantPC or 2-AB dyes. Best practices for robust methods will be introduced. Method d...
      Speaker: Lance Kasper
      Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
      1 1
      SEP 22, 2020 | 7:00 AM
      Cells in Motion - How to optimize your shake flask and bioreactor cultures
      Cells in Motion - How to optimize your shake flask and bioreactor...
      DATE: September 22, 2020 TIME: 7am PDT, 10am EDT, 4pm CEST Shakers and bioreactors are established versatile systems for cultivating microorganism, plant, and animal cells......
      Speaker: Ines Hartmann , Ankita Desai
      Sponsored By: Eppendorf
      17 2
      SEP 17, 2020 | 8:00 AM
      Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9 Ribonucleoproteins Using a cGMP- Compliant Cell Engineering Platform
      Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9...
      DATE: September 17, 2020 TIME: 8:00am PT CRISPR-Cas9 has tremendous potential as a therapeutic tool for treating human diseases. However, prolonged expression of the nuclease and gRNA from v...
      Speaker: Peter Gee, Ph.D.
      Sponsored By: MaxCyte®
      6
      SEP 17, 2020 | 12:00 AM
      Testing for SARS-CoV-2: The Cleveland Clinic Experience
      Testing for SARS-CoV-2: The Cleveland Clinic Experience
      This presentation will discuss the use of the FDA EUA process to implement SARS-CoV-2 assays to address the COVID-19 pandemic. The use of a team-based approach, through an Incident Command s...
      Speaker: Gary Procop, MD, MS
      Presented at: Coronavirus Series
      3
      SEP 10, 2020 | 11:00 AM
      Optimizing the extraction of human microbiome samples
      Optimizing the extraction of human microbiome samples
      Learning Objectives: 1. Understand the challenges of extracting DNA from human samples for microbiome analysis, and learn about the best technologies for accomplishing this 2. Learn about pr...
      Speaker: Dominic O'Neil, MS, MBA
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      AUG 27, 2020 | 7:00 AM
      SARS-CoV-2 Quality Control for Molecular and Serology assays
      SARS-CoV-2 Quality Control for Molecular and Serology assays
      SARS-CoV-2 has created significant challenges for laboratories, requiring the development, validation, and scale up of testing in a very short time period--often this was done for multiple m...
      Speaker: Duane Newton, PhD, D(ABMM), FIDSA , Elitza S. Theel, PhD, D(ABMM)
      Presented at: A Bio-Rad Quality Control Virtual Conference
      Sponsored By: Bio-Rad Laboratories
      20 2
      AUG 27, 2020 | 7:00 AM
      Atlas of the SARS-CoV-2 Proteome
      Atlas of the SARS-CoV-2 Proteome
      DATE: August 27, 2020 TIME: 7:00am PT Novel anti-viral medications, including biologics and small molecule inhibitors, as well as serologic diagnostic tool sets are in urgent demand to fight...
      Speaker: Yuning Chen, Ph.D.
      Sponsored By: Sino Biological
      32 3
      AUG 20, 2020 | 10:00 AM
      A Novel Method for the Isolation of Highly Pure Carcinoma Cell Populations from FFPE Tissue Improves Sensitivity for Detecting Somatic Mutations
      A Novel Method for the Isolation of Highly Pure Carcinoma Cell...
      DATE: August 20, 2020 TIME: 10:00am PT, 1:00pm ET Millions of formalin-fixed paraffin-embedded (FFPE) tissue specimens are archived annually. The enormous number of FFPE specimens available...
      Speaker: Carina Emery
      Sponsored By: Miltenyi Biotec
      21 1
      AUG 11, 2020 | 10:00 AM
      Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
      Better resolution for CE-SDS analysis of new biopharmaceutical...
      DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
      Speaker: Andras Guttman, PhD
      Sponsored By: SCIEX
      9 4
      AUG 06, 2020 | 10:00 AM
      Part IV: SPARC - A method to genetically manipulate precise proportions of cells
      Part IV: SPARC - A method to genetically manipulate precise proportions...
      Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
      Speaker: Jesse Isaacman-Beck, PhD
      Presented at: 2020 Beckman Symposium
      2
      AUG 06, 2020 | 12:00 AM
      SPARC - A method to genetically manipulate precise proportions of cells
      SPARC - A method to genetically manipulate precise proportions...
      Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
      Speaker: Jesse Isaacman-Beck, PhD
      Presented at: 2020 Beckman Symposium
      1
      JUL 29, 2020 | 5:00 PM
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
      Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
      Speaker: Brad Larson
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 29, 2020 | 12:00 AM
      3D Culture Methods and Imaging Considerations
      3D Culture Methods and Imaging Considerations
      The use of three‐dimensional (3D) culture models is rapidly expanding due to their recognition as representing more structurally and physiologically relevant models of in vivo biology. 3D ce...
      Speaker: Brad Larson , Valerie Sodi, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 12:00 AM
      Tools and Techniques for Optimizing Cell Proliferation Studies
      Tools and Techniques for Optimizing Cell Proliferation Studies
      In this webinar we provide a detailed review of available methods for measuring cell proliferation, with a particular focus on recent assay innovations, including both 2D and 3D formats. Thi...
      Speaker: Joe Clayton, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
    OCT 21, 2020 | 12:00 AM
    Overcoming Challenges Analyzing Heavy Metals in Cannabis by ICP-MS
    Overcoming Challenges Analyzing Heavy Metals in Cannabis by ICP-MS
    There are many obstacles to overcome when analyzing Heavy Metals in Cannabis by ICPMS. Cannabis matrices can be difficult to prepare and analyze due to the complex components of products tha...
    Speaker: Shianna Hines
    Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
    1
    OCT 14, 2020 | 10:00 AM
    Strategies to Optimize Drug Testing:  What's In Your Panel and What Are You Missing?
    Strategies to Optimize Drug Testing: What's In Your Panel and...
    DATE: October 14, 2020 TIME: 10:00am PT Do you need help in planning your drug testing protocols? Did you know that a “one size fits all” approach to drug testing does not apply...
    Speaker: Jaime Noguez, Ph.D
    Sponsored By: Thermo Fisher Scientific
    15
    SEP 30, 2020 | 6:00 AM
    Enhancing efficiency and specificity with improved CRISPR components and a new CRISPR analysis pipeline
    Enhancing efficiency and specificity with improved CRISPR components...
    Genome editing with an expanded CRISPR-Cas tool set increases the opportunity to make intentional, targeted changes in the genome. Furthermore, improved specificity of genome editing and abi...
    Speaker: Ashley Jacobi
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: IDT
    2
    SEP 30, 2020 | 12:00 AM
    CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
    CRISPR/Cas9 as a tool to model and study cancer - insights and...
    Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
    Speaker: Grace R. Anderson, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 30, 2020 | 12:00 AM
    Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for Targeted Sequencing
    Measuring Outcomes of CRISPR Experiments & Leveraging Cas9 for...
    CRISPR experiments are a powerful tool which are easy to carry out, however it is more difficult to determine the outcome of these experiments, and to ensure that only the desired targets we...
    Speaker: Jonas Korlach, PhD
    Presented at: CRISPR Virtual Event Series 2020
    1
     
     
  • SEP 29, 2020 | 8:00 AM
    Microbial Quality Control in Manufacturing of Medicinal Products
    Microbial Quality Control in Manufacturing of Medicinal Products
    DATE: September 29, 2020 TIME: 8:00 am PDT There is a steady increase in FDA 483s related to microbiology. Though most are for sterile products, non-sterile and terminally sterilized product...
    Speaker: Ziva Abraham
    Sponsored By: Sartorius
    19 5
    SEP 23, 2020 | 4:30 PM
    Anatomy of a nucleic acid sample preparation
    Anatomy of a nucleic acid sample preparation
    There are many methods of nucleic acid isolation. Each technology offers different approaches of purification of the template. However, it is important to control carry over of “proces...
    Speaker: Katherine Mechling
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2 1
    SEP 23, 2020 | 1:30 PM
    Analytic Options for Mass Cytometry Data
    Analytic Options for Mass Cytometry Data
    From data to insight: Explore the full potential of high dimensional data by leveraging machine learning algorithms 1:30–2:00 pm PDT Presented By: Qianjun Zhang, MS Utilizing FCS Expre...
    Speaker: Qianjun Zhang, MS , Sean Burke, MS , Thiru Selvanantham, PhD , Beth Lindroth Hill, PhD , Jared K. Burks, PhD , Trevor McKee, PhD , Donald Allen, BS
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
    SEP 23, 2020 | 2:30 PM
    Sponsor-led Round Table Discussion: Vapor Tech: Making the Switch to Ceramics
    Sponsor-led Round Table Discussion: Vapor Tech: Making the Switch...
    One of the most prevalent consumption methods in the industry has been oils utilizing 510 thread cartridges. Over the last decade, consumers and manufacturers in this realm have refocused fr...
    Speaker: Moderator: Daniel Hwang
    Presented at: MJ Unpacked - Midwest
    1
    SEP 23, 2020 | 7:30 AM
    Cell Culture Troubleshooting Tips and Tricks
    Cell Culture Troubleshooting Tips and Tricks
    Cell culture continues to be a critical tool for most life science research and applications. From HeLa to iPSCs and 3D to organoids, culture methods have become more advanced and techniques...
    Speaker: Marina Wiklander, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    6
     
     
  • SEP 22, 2020 | 9:15 AM
    Optimizing Glycan Separations and Analysis by HPLC
    Optimizing Glycan Separations and Analysis by HPLC
    This talk will explore HILIC chromatography methods for the analysis of released N-glycans labeled with InstantPC or 2-AB dyes. Best practices for robust methods will be introduced. Method d...
    Speaker: Lance Kasper
    Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
    1 1
    SEP 22, 2020 | 7:00 AM
    Cells in Motion - How to optimize your shake flask and bioreactor cultures
    Cells in Motion - How to optimize your shake flask and bioreactor...
    DATE: September 22, 2020 TIME: 7am PDT, 10am EDT, 4pm CEST Shakers and bioreactors are established versatile systems for cultivating microorganism, plant, and animal cells......
    Speaker: Ines Hartmann , Ankita Desai
    Sponsored By: Eppendorf
    17 2
    SEP 17, 2020 | 8:00 AM
    Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9 Ribonucleoproteins Using a cGMP- Compliant Cell Engineering Platform
    Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9...
    DATE: September 17, 2020 TIME: 8:00am PT CRISPR-Cas9 has tremendous potential as a therapeutic tool for treating human diseases. However, prolonged expression of the nuclease and gRNA from v...
    Speaker: Peter Gee, Ph.D.
    Sponsored By: MaxCyte®
    6
    SEP 17, 2020 | 12:00 AM
    Testing for SARS-CoV-2: The Cleveland Clinic Experience
    Testing for SARS-CoV-2: The Cleveland Clinic Experience
    This presentation will discuss the use of the FDA EUA process to implement SARS-CoV-2 assays to address the COVID-19 pandemic. The use of a team-based approach, through an Incident Command s...
    Speaker: Gary Procop, MD, MS
    Presented at: Coronavirus Series
    3
    SEP 10, 2020 | 11:00 AM
    Optimizing the extraction of human microbiome samples
    Optimizing the extraction of human microbiome samples
    Learning Objectives: 1. Understand the challenges of extracting DNA from human samples for microbiome analysis, and learn about the best technologies for accomplishing this 2. Learn about pr...
    Speaker: Dominic O'Neil, MS, MBA
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
     
     
  • AUG 27, 2020 | 7:00 AM
    SARS-CoV-2 Quality Control for Molecular and Serology assays
    SARS-CoV-2 Quality Control for Molecular and Serology assays
    SARS-CoV-2 has created significant challenges for laboratories, requiring the development, validation, and scale up of testing in a very short time period--often this was done for multiple m...
    Speaker: Duane Newton, PhD, D(ABMM), FIDSA , Elitza S. Theel, PhD, D(ABMM)
    Presented at: A Bio-Rad Quality Control Virtual Conference
    Sponsored By: Bio-Rad Laboratories
    20 2
    AUG 27, 2020 | 7:00 AM
    Atlas of the SARS-CoV-2 Proteome
    Atlas of the SARS-CoV-2 Proteome
    DATE: August 27, 2020 TIME: 7:00am PT Novel anti-viral medications, including biologics and small molecule inhibitors, as well as serologic diagnostic tool sets are in urgent demand to fight...
    Speaker: Yuning Chen, Ph.D.
    Sponsored By: Sino Biological
    32 3
    AUG 20, 2020 | 10:00 AM
    A Novel Method for the Isolation of Highly Pure Carcinoma Cell Populations from FFPE Tissue Improves Sensitivity for Detecting Somatic Mutations
    A Novel Method for the Isolation of Highly Pure Carcinoma Cell...
    DATE: August 20, 2020 TIME: 10:00am PT, 1:00pm ET Millions of formalin-fixed paraffin-embedded (FFPE) tissue specimens are archived annually. The enormous number of FFPE specimens available...
    Speaker: Carina Emery
    Sponsored By: Miltenyi Biotec
    21 1
    AUG 11, 2020 | 10:00 AM
    Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
    Better resolution for CE-SDS analysis of new biopharmaceutical...
    DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
    Speaker: Andras Guttman, PhD
    Sponsored By: SCIEX
    9 4
    AUG 06, 2020 | 10:00 AM
    Part IV: SPARC - A method to genetically manipulate precise proportions of cells
    Part IV: SPARC - A method to genetically manipulate precise proportions...
    Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
    Speaker: Jesse Isaacman-Beck, PhD
    Presented at: 2020 Beckman Symposium
    2
     
     
  • AUG 06, 2020 | 12:00 AM
    SPARC - A method to genetically manipulate precise proportions of cells
    SPARC - A method to genetically manipulate precise proportions...
    Many experimental approaches rely on controlling gene expression in select subsets of cells within an individual animal. However, reproducibly targeting transgene expression to specific frac...
    Speaker: Jesse Isaacman-Beck, PhD
    Presented at: 2020 Beckman Symposium
    1
    JUL 29, 2020 | 5:00 PM
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
    Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
    Speaker: Brad Larson
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
    JUL 29, 2020 | 12:00 AM
    3D Culture Methods and Imaging Considerations
    3D Culture Methods and Imaging Considerations
    The use of three‐dimensional (3D) culture models is rapidly expanding due to their recognition as representing more structurally and physiologically relevant models of in vivo biology. 3D ce...
    Speaker: Brad Larson , Valerie Sodi, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 29, 2020 | 12:00 AM
    Tools and Techniques for Optimizing Cell Proliferation Studies
    Tools and Techniques for Optimizing Cell Proliferation Studies
    In this webinar we provide a detailed review of available methods for measuring cell proliferation, with a particular focus on recent assay innovations, including both 2D and 3D formats. Thi...
    Speaker: Joe Clayton, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
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