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Microglia
Microglia: glial cells, derived from the germ layer, mesoderm, that function as scavengers (macrophages) in the central nervous system. This, in turn, forms part of the reticuloendothelial system.
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C.E. CREDITS
Brain organoids are self-assembled three-dimensional cellular aggregates with cell types and tissue architectures that resemble the embryonic human brain. As they recapitulate many key featu...
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The encapsulated fungus Cryptococcus neoformans is the most common cause of fungal meningitis, with the highest rate of cryptococcosis found in AIDS patients. Despite antifungal treatment, c...
AUG 23, 2023 | 10:00 AM
C9orf72 repeat expansions cause inherited amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) and result in both loss of C9orf72 protein expression and production of potentially...
MAR 08, 2023 | 6:00 AM
Mild traumatic brain injuries (mTBIs) are a prevalent health issue in North America. There is increasing pressure to utilize ecologically valid models of closed-head mTBI in the preclinical...
FEB 23, 2023 | 8:00 AM
Date: February 23, 2023 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) The RNAscope in situ hybridization (ISH) technology is a powerful method for detecting gene expression with spatial an...
MAY 04, 2022 | 5:30 AM
Neurological manifestations, including headache, altered mental status, and stroke, are a major complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and cor...
AUG 25, 2021 | 1:30 PM
In this preliminary experiment, we used spatial transcriptomics to assess the gene expression profiles of microglia or astrocytes in relation to their distance from plaques. We compared 18-m...
JUN 10, 2021 | 10:00 AM
Date: June 10, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Microglia, the primary brain macrophages, regulate a plethora of processes that impact the organization of neural circuits, including sy...
APR 21, 2021 | 5:00 PM
Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
JUL 07, 2020 | 6:00 AM
Brain malignancies can either originate from within the CNS (gliomas) or invade from other locations in the body (metastases). A highly immunosuppressive tumor microenvironment (TME) influen...
MAR 11, 2020 | 10:30 AM
The accumulation of neurotoxic amyloid beta peptides and/or neurofibrillary tangle formation are key pathological hallmarks of neurodegenerative diseases including but not limited to Alzheim...
