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    Systems Biology

    Systems Biology: Systems biology is the computational and mathematical modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach to biological research.

    Webinars

    • MAR 11, 2020 | 12:00 PM
      PANEL: Cracking a Neural Circuit's Function Through High-Resolution Physiology, Connectomics, and Computational Modeling
      PANEL: Cracking a Neural Circuit's Function Through High-Resolution...
      Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
      Speaker: Emre Aksay, PhD , Mark Goldman, PhD , Sebastian Seung, PhD , Ashwin Vishwanathan, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1 1
      MAR 11, 2020 | 12:00 PM
      PANEL: Thought to action: developing brain machine interfaces to assist individuals with paralysis
      PANEL: Thought to action: developing brain machine interfaces...
      Brain machine interfaces (BMIs) aim to help patients with paralysis to use their recorded brain activity to control assistive devices. BMI research requires the collaboration of neuroscienti...
      Speaker: Tyson Aflalo, PhD , Richard Andersen, PhD , Spencer Kellis, PhD , Charles Liu, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 10:30 AM
      PANEL: The Berghia Brain Project: A Team Approach to Understanding Whole-Brain Control of State-Dependent, Motivated Behaviors
      PANEL: The Berghia Brain Project: A Team Approach to Understanding...
      The neural basis of simple rhythmic and reflexive behaviors such as swimming and gill withdrawal have been successfully studied in nudibranchs and other gastropod molluscs because the brains...
      Speaker: Paul Katz, PhD , Jeff Lichtman, MD, PhD , William Frost, PhD , Deidre Lyons, PhD , Vince Lyzinski, PhD, B.Sc, M.Sc, M.Sc.E.
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 9:00 AM
      PANEL: Neural circuit mechanisms of memory replay
      PANEL: Neural circuit mechanisms of memory replay
      Although neuroscience has provided a great deal of information about how neurons work, the fundamental question of how neurons function together in a network to produce cognition has been di...
      Speaker: György Buzsáki, PhD , Attila Losonczy , Mark Schnitzer , Ivan Soltesz
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 9:00 AM
      Keynote Presentation: The BRAIN Initiative and its Promise for the Treatment of Neuro/Mental/Substance Abuse Disorders
      Keynote Presentation: The BRAIN Initiative and its Promise for...
      The US Brain Research through Advancing Innovative Neurotechnologies is a research program focused on building fundamental knowledge of how brain circuits process information to enable human...
      Speaker: Walter Koroshetz, MD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 7:30 AM
      PANEL: Neuronal Circuit Resilience - How the Brain Manages to Maintain Reliable Behaviors with Unreliable Neurons
      PANEL: Neuronal Circuit Resilience - How the Brain Manages to...
      Brain function is remarkably reliable despite the imprecise performance of neurons, and the continuous perturbations caused by aging, disease or injury. How does the brain succeed in produci...
      Speaker: Adrienne Fairhall, PhD , Tim Gardner , Carlos Lois, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 7:30 AM
      Keynote Presentation: Interplay between LRRK2 protein kinase and Rab GTPases in Parkinson's disease
      Keynote Presentation: Interplay between LRRK2 protein kinase and...
      Autosomal dominant missense mutations that hyperactivate the LRRK2 protein kinase are a common cause of inherited Parkinson’s disease and therapeutic efficacy of LRRK2 inhibitors is be...
      Speaker: Dario Alessi, FRS FMedSci FRSE
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 6:00 AM
      PANEL: Sensorimotor Processing, Decision Making, and Internal States: Towards a Realistic Multiscale Circuit Model of the Larval Zebrafish Brain
      PANEL: Sensorimotor Processing, Decision Making, and Internal...
      We present here a framework to generate a realistic multiscale circuit model of the larval zebrafish brain – the multiscale virtual fish (MVF). The model will be based on algorithms in...
      Speaker: Florian Engert, PhD , Jeff Lichtman, MD, PhD , Haim Sompolinsky
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 6:00 AM
      PANEL: The Neural Control of Locomotion, an Integrative Approach
      PANEL: The Neural Control of Locomotion, an Integrative Approach
      The locomotion of humans and other animals requires a seamless flow of information from sensory modalities all the way to the motor periphery. As such, locomotion is an excellent system for...
      Speaker: Michael Dickinson, PhD , Anthony Azevedo, PhD , Clare Howard, PhD , Luke Brezovec , Sasha Rayshubskiy , Emily Palmer
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 05, 2020 | 9:00 AM
      An Update on H. pylori testing with a focus on the Houston Consensus recommendations
      An Update on H. pylori testing with a focus on the Houston Consensus...
      Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
      Speaker: David Graham, MD
      8
      MAR 03, 2020 | 9:00 AM
      The Importance of CPO Carriers Within the Healthcare System
      The Importance of CPO Carriers Within the Healthcare System
      DATE: March 3, 2020 TIME: 9:00am PT, 12:00pm ET Despite the advances of new drugs and the lowering of carbapenem breakpoints to enhance detection of CRE, there should be no complacency about...
      Speaker: Kenneth Thomson, PhD
      Presented at: BD MAX Webinar Library
      Sponsored By: BD
      5 1
      FEB 26, 2020 | 12:00 PM
      Characterizing the role of B cells in Response to Immunotherapy with the NanoString GeoMx Platform
      Characterizing the role of B cells in Response to Immunotherapy...
      Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
      Speaker: Sarah Warren, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      Sponsored By: NanoString Technologies
      1
      FEB 26, 2020 | 9:00 AM
      The use of 3D Models in Hepatic Biology
      The use of 3D Models in Hepatic Biology
      DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
      Speaker: Julia Tritapoe , David Kuninger, PhD
      Sponsored By: Thermo Fisher Scientific
      12 1
      FEB 26, 2020 | 7:30 AM
      Keynote Presentation: Emerging Drug Combinations: Evolution From Pre-Clinical Discovery to Clinical Development
      Keynote Presentation: Emerging Drug Combinations: Evolution From...
      Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
      Speaker: Khyati Shah, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      FEB 25, 2020 | 9:00 AM
      CAR-T Generation for Identity, Purity and Potency Assay Testing
      CAR-T Generation for Identity, Purity and Potency Assay Testing
      Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
      Speaker: Tia Hexom, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 1
      FEB 19, 2020 | 11:00 AM
      Emerging as the New Gold Standard in Quality & Safety: Parallel DNA Based Cannabis Testing of Multiple Microbes
      Emerging as the New Gold Standard in Quality & Safety: Parallel...
      DATE: February 19, 2020TIME: 11:00am PST, 2:00pm EST...
      Speaker: Michael Hogan, Ph.D. , Benjamin Katchman, Ph.D.
      Sponsored By: PathogenDx
      7
      JAN 23, 2020 | 9:00 AM
      A Workflow for Knock-in Genome Editing: Simplified
      A Workflow for Knock-in Genome Editing: Simplified
      DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
      Speaker: Matthew Poling, PhD
      Sponsored By: Thermo Fisher Scientific
      17
      JAN 14, 2020 | 9:00 AM
      Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
      Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
      Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
      Speaker: Roy Sherwood, BSc, MSC, DPhil
      Sponsored By: Diasorin S.p.A.
      5
      JAN 14, 2020 | 8:00 AM
      CiPA initiative and validation of high-throughput methods to characterize compound effects in human iPSC-derived cardiomyocytes
      CiPA initiative and validation of high-throughput methods to characterize...
      DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
      Speaker: Muthukrishnan Renganathan, PhD , Panida Lertkiatmongkol, PhD , Oksana Sirenko, PhD , Carole Crittenden
      Sponsored By: Molecular Devices, Eurofins Discovery
      3
      JAN 01, 2020 | 6:00 AM
      Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
      Uncovering the mechanism of stress-resistant DNA replication in...
      Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
      Speaker: Chames Kermi, PhD, PharmD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Bridging the translational gap in rodent behavioral testing using touchscreens and the MouseBytes Open science data repository
      Bridging the translational gap in rodent behavioral testing using...
      Open Science has changed research by making data accessible and shareable, contributing to replicability to accelerate and disseminate knowledge. However, for rodent cognitive studies the av...
      Speaker: Marco A.M. Prado, Pharm, MSc, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Organoids: A Revolutionary New Tool for Drug Screening
      Organoids: A Revolutionary New Tool for Drug Screening
      “The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
      Speaker: Rekha Pal, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Selective D4R Ligands Reveal Structure-Activity Relationships that Engender Agonist Efficacy
      Selective D4R Ligands Reveal Structure-Activity Relationships...
      The dopamine D4 receptor (D4R) is enriched in the prefrontal cortex where it plays important roles in cognition, attention, decision making and executive function. Novel D4R-selective ligand...
      Speaker: Comfort Boateng, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Acoustically Targeted Molecular Neuromodulation
      Acoustically Targeted Molecular Neuromodulation
      The study of biological function in intact organisms and the development of targeted cellular therapeutics necessitate methods to image and control cellular function in vivo. Technologies su...
      Speaker: Mikhail Shapiro, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      2
    MAR 11, 2020 | 12:00 PM
    PANEL: Cracking a Neural Circuit's Function Through High-Resolution Physiology, Connectomics, and Computational Modeling
    PANEL: Cracking a Neural Circuit's Function Through High-Resolution...
    Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
    Speaker: Emre Aksay, PhD , Mark Goldman, PhD , Sebastian Seung, PhD , Ashwin Vishwanathan, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1 1
    MAR 11, 2020 | 12:00 PM
    PANEL: Thought to action: developing brain machine interfaces to assist individuals with paralysis
    PANEL: Thought to action: developing brain machine interfaces...
    Brain machine interfaces (BMIs) aim to help patients with paralysis to use their recorded brain activity to control assistive devices. BMI research requires the collaboration of neuroscienti...
    Speaker: Tyson Aflalo, PhD , Richard Andersen, PhD , Spencer Kellis, PhD , Charles Liu, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 10:30 AM
    PANEL: The Berghia Brain Project: A Team Approach to Understanding Whole-Brain Control of State-Dependent, Motivated Behaviors
    PANEL: The Berghia Brain Project: A Team Approach to Understanding...
    The neural basis of simple rhythmic and reflexive behaviors such as swimming and gill withdrawal have been successfully studied in nudibranchs and other gastropod molluscs because the brains...
    Speaker: Paul Katz, PhD , Jeff Lichtman, MD, PhD , William Frost, PhD , Deidre Lyons, PhD , Vince Lyzinski, PhD, B.Sc, M.Sc, M.Sc.E.
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 9:00 AM
    PANEL: Neural circuit mechanisms of memory replay
    PANEL: Neural circuit mechanisms of memory replay
    Although neuroscience has provided a great deal of information about how neurons work, the fundamental question of how neurons function together in a network to produce cognition has been di...
    Speaker: György Buzsáki, PhD , Attila Losonczy , Mark Schnitzer , Ivan Soltesz
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 9:00 AM
    Keynote Presentation: The BRAIN Initiative and its Promise for the Treatment of Neuro/Mental/Substance Abuse Disorders
    Keynote Presentation: The BRAIN Initiative and its Promise for...
    The US Brain Research through Advancing Innovative Neurotechnologies is a research program focused on building fundamental knowledge of how brain circuits process information to enable human...
    Speaker: Walter Koroshetz, MD
    Presented at: Neuroscience Virtual Event Series 2020
    1
     
     
  • MAR 11, 2020 | 7:30 AM
    PANEL: Neuronal Circuit Resilience - How the Brain Manages to Maintain Reliable Behaviors with Unreliable Neurons
    PANEL: Neuronal Circuit Resilience - How the Brain Manages to...
    Brain function is remarkably reliable despite the imprecise performance of neurons, and the continuous perturbations caused by aging, disease or injury. How does the brain succeed in produci...
    Speaker: Adrienne Fairhall, PhD , Tim Gardner , Carlos Lois, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 7:30 AM
    Keynote Presentation: Interplay between LRRK2 protein kinase and Rab GTPases in Parkinson's disease
    Keynote Presentation: Interplay between LRRK2 protein kinase and...
    Autosomal dominant missense mutations that hyperactivate the LRRK2 protein kinase are a common cause of inherited Parkinson’s disease and therapeutic efficacy of LRRK2 inhibitors is be...
    Speaker: Dario Alessi, FRS FMedSci FRSE
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 6:00 AM
    PANEL: Sensorimotor Processing, Decision Making, and Internal States: Towards a Realistic Multiscale Circuit Model of the Larval Zebrafish Brain
    PANEL: Sensorimotor Processing, Decision Making, and Internal...
    We present here a framework to generate a realistic multiscale circuit model of the larval zebrafish brain – the multiscale virtual fish (MVF). The model will be based on algorithms in...
    Speaker: Florian Engert, PhD , Jeff Lichtman, MD, PhD , Haim Sompolinsky
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 6:00 AM
    PANEL: The Neural Control of Locomotion, an Integrative Approach
    PANEL: The Neural Control of Locomotion, an Integrative Approach
    The locomotion of humans and other animals requires a seamless flow of information from sensory modalities all the way to the motor periphery. As such, locomotion is an excellent system for...
    Speaker: Michael Dickinson, PhD , Anthony Azevedo, PhD , Clare Howard, PhD , Luke Brezovec , Sasha Rayshubskiy , Emily Palmer
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 05, 2020 | 9:00 AM
    An Update on H. pylori testing with a focus on the Houston Consensus recommendations
    An Update on H. pylori testing with a focus on the Houston Consensus...
    Recommendations for key factors in testing and diagnosis of H. pylori infections to include information on appropriate patients for H.pylori testing, current testing options, post treatment...
    Speaker: David Graham, MD
    8
     
     
  • MAR 03, 2020 | 9:00 AM
    The Importance of CPO Carriers Within the Healthcare System
    The Importance of CPO Carriers Within the Healthcare System
    DATE: March 3, 2020 TIME: 9:00am PT, 12:00pm ET Despite the advances of new drugs and the lowering of carbapenem breakpoints to enhance detection of CRE, there should be no complacency about...
    Speaker: Kenneth Thomson, PhD
    Presented at: BD MAX Webinar Library
    Sponsored By: BD
    5 1
    FEB 26, 2020 | 12:00 PM
    Characterizing the role of B cells in Response to Immunotherapy with the NanoString GeoMx Platform
    Characterizing the role of B cells in Response to Immunotherapy...
    Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
    Speaker: Sarah Warren, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    Sponsored By: NanoString Technologies
    1
    FEB 26, 2020 | 9:00 AM
    The use of 3D Models in Hepatic Biology
    The use of 3D Models in Hepatic Biology
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    Speaker: Julia Tritapoe , David Kuninger, PhD
    Sponsored By: Thermo Fisher Scientific
    12 1
    FEB 26, 2020 | 7:30 AM
    Keynote Presentation: Emerging Drug Combinations: Evolution From Pre-Clinical Discovery to Clinical Development
    Keynote Presentation: Emerging Drug Combinations: Evolution From...
    Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
    Speaker: Khyati Shah, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    FEB 25, 2020 | 9:00 AM
    CAR-T Generation for Identity, Purity and Potency Assay Testing
    CAR-T Generation for Identity, Purity and Potency Assay Testing
    Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
    Speaker: Tia Hexom, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 1
     
     
  • FEB 19, 2020 | 11:00 AM
    Emerging as the New Gold Standard in Quality & Safety: Parallel DNA Based Cannabis Testing of Multiple Microbes
    Emerging as the New Gold Standard in Quality & Safety: Parallel...
    DATE: February 19, 2020TIME: 11:00am PST, 2:00pm EST...
    Speaker: Michael Hogan, Ph.D. , Benjamin Katchman, Ph.D.
    Sponsored By: PathogenDx
    7
    JAN 23, 2020 | 9:00 AM
    A Workflow for Knock-in Genome Editing: Simplified
    A Workflow for Knock-in Genome Editing: Simplified
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    Speaker: Matthew Poling, PhD
    Sponsored By: Thermo Fisher Scientific
    17
    JAN 14, 2020 | 9:00 AM
    Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
    Fecal Elastase-1 - a Biomarker for Pancreatic Exocrine Insufficiency
    Fecal elastase-1 – a biomarker for pancreatic exocrine insufficiency(EPI) continues to gain traction as an ideal biomarker for assessing EPI. This presentation will include a review of...
    Speaker: Roy Sherwood, BSc, MSC, DPhil
    Sponsored By: Diasorin S.p.A.
    5
    JAN 14, 2020 | 8:00 AM
    CiPA initiative and validation of high-throughput methods to characterize compound effects in human iPSC-derived cardiomyocytes
    CiPA initiative and validation of high-throughput methods to characterize...
    DATE: January 14, 2019 TIME: 8:00am PST Drug-induced QT interval prolongation and Torsades de Pointes (TdP) arrhythmias are the leading causes for drug withdrawals from market and compound a...
    Speaker: Muthukrishnan Renganathan, PhD , Panida Lertkiatmongkol, PhD , Oksana Sirenko, PhD , Carole Crittenden
    Sponsored By: Molecular Devices, Eurofins Discovery
    3
    JAN 01, 2020 | 6:00 AM
    Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
    Uncovering the mechanism of stress-resistant DNA replication in...
    Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
    Speaker: Chames Kermi, PhD, PharmD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
     
     
  • JAN 01, 2020 | 6:00 AM
    Bridging the translational gap in rodent behavioral testing using touchscreens and the MouseBytes Open science data repository
    Bridging the translational gap in rodent behavioral testing using...
    Open Science has changed research by making data accessible and shareable, contributing to replicability to accelerate and disseminate knowledge. However, for rodent cognitive studies the av...
    Speaker: Marco A.M. Prado, Pharm, MSc, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Organoids: A Revolutionary New Tool for Drug Screening
    Organoids: A Revolutionary New Tool for Drug Screening
    “The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
    Speaker: Rekha Pal, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Selective D4R Ligands Reveal Structure-Activity Relationships that Engender Agonist Efficacy
    Selective D4R Ligands Reveal Structure-Activity Relationships...
    The dopamine D4 receptor (D4R) is enriched in the prefrontal cortex where it plays important roles in cognition, attention, decision making and executive function. Novel D4R-selective ligand...
    Speaker: Comfort Boateng, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    JAN 01, 2020 | 6:00 AM
    Acoustically Targeted Molecular Neuromodulation
    Acoustically Targeted Molecular Neuromodulation
    The study of biological function in intact organisms and the development of targeted cellular therapeutics necessitate methods to image and control cellular function in vivo. Technologies su...
    Speaker: Mikhail Shapiro, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    2
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