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    Tumor development

    Tumor development, or tumorigenesis, broadly describes the process by which normal cells gain malignant properties. Tumor development includes growth functions like cellular differentiation, proliferation, and metastasis.

    Webinars

    • FEB 27, 2019 | 7:30 AM
      Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
      Keynote Presentation: Second Harmonic Generation Detection of...
      Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
      Speaker: Frank McCormick, PhD
      Presented at: Drug Discovery Virtual Event Series 2019
      1
      JAN 31, 2019 | 7:30 AM
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
      Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
      Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
      Speaker: A.C. Matin, PhD
      Presented at: BioProcessing Virtual Event Series 2019
      1
      DEC 13, 2018 | 9:00 AM
      Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using Models of Endocrine Resistance
      Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using...
      DATE: December 13 15,2018TIME: 09:00am PST, 12:00pm EST Breast cancers are classified into three main subtypes according to their receptor status: estrogen receptor-positive...
      Speaker: Hillary Stires, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      NOV 28, 2018 | 7:00 AM
      Discover how single-cell RNA sequencing provides deeper insights into lung cancer biology
      Discover how single-cell RNA sequencing provides deeper insights...
      DATE: November 28, 2018TIME:  7:00AM PSTSingle-cell genomics enables a deep dive into the mechanisms responsible for health and disease, in areas from cancer biology to neurob...
      Speaker: Bernard Thienpont , Annika Branting , Pawel Zajac, Ph.D.
      Sponsored By: Illumina, 10x Genomics
      5
      NOV 15, 2018 | 12:00 PM
      Better Knowledge, Better Care: Precision Medicine for Any Cancer, Any Assay, on Your Platform
      Better Knowledge, Better Care: Precision Medicine for Any Cancer,...
      QIAGEN helps your team focus on the opportunities, not the obstacles, with an end-to-end clinical testing solution. During this talk, we will present a lung cancer case study to show how QIAG...
      Speaker: Raed Samara, PhD , Dan Richards, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
      Sponsored By: QIAGEN
      2
      NOV 15, 2018 | 7:00 AM
      Use of stem-cell derived endothelial cells for disease relevant cell modeling and drug discovery
      Use of stem-cell derived endothelial cells for disease relevant...
      The use of human pluripotent stem cells (hPSCs) for in vitro disease-modeling is limited by the lack of robust and efficient protocols for the differentiation of relevant adult cell types. Pr...
      Speaker: Filip Roudnicky
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      8
      NOV 14, 2018 | 9:00 AM
      Accelerating Cancer Research and Clinical Innovations Using OncoLand
      Accelerating Cancer Research and Clinical Innovations Using OncoLand
      With significant decrease in the cost of sequencing in numerous commercial as well as cancer center–driven initiatives, genomic profiling is increasingly becoming routine across multipl...
      Speaker: Bing Zhou, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      NOV 07, 2018 | 8:00 PM
      Analysis of Surface Antigens on Exosomes
      Analysis of Surface Antigens on Exosomes
      DATE: November 7, 2018TIME: 8:00PM PSTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metasta...
      Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
      Sponsored By: Thermo Fisher Scientific
      3 1
      NOV 07, 2018 | 7:00 AM
      Analysis of Surface Antigens on Exosomes
      Analysis of Surface Antigens on Exosomes
      DATE: November 7, 2018TIME: 7:00AM PDTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metastasis a...
      Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
      Sponsored By: Thermo Fisher Scientific
      11 1
      NOV 01, 2018 | 12:00 AM
      Advanced 3D cell models for cancer biology using real time live-cell analysis
      Advanced 3D cell models for cancer biology using real time live-cell...
      Integrated protocols and live-cell analysis solutions for different 3D tumor modelsIn the search for greater clinical translation, cancer researchers are increasingly turning to more comp...
      Speaker: Kalpana Patel
      Presented at: Dimension of Time: From Culture to Assay
      2
      NOV 01, 2018 | 12:00 AM
      Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
      Glycosylation and stabilization of programmed death ligand-1 suppresses...
      The success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on cancer cell and immune cell interaction, how cancer cells i...
      Speaker: Chia-Wei Li, PhD
      Presented at: Dimension of Time: From Culture to Assay
      1
      OCT 25, 2018 | 8:00 AM
      Disease modeling and cancer therapy in stem cell-derived 3D organoid systems
      Disease modeling and cancer therapy in stem cell-derived 3D organoid...
      DATE: October 25, 2018TIME:  08:00am PDT, 11:00am EDT While the significance of the microbiome is unprecedented, a thorough study to dissect the role of individual popul...
      Speaker: Devanjali Dutta, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      OCT 23, 2018 | 10:00 AM
      Pediatric Cancer Genomics: Accessing Data, Tools and Visualizations in St. Jude Cloud
      Pediatric Cancer Genomics: Accessing Data, Tools and Visualizations...
      DATE: October 23, 2018TIME: 10:00am PDT, 1:00pm EDT Next-generation genomic sequencing is transforming what is known about pediatric cancer and how we treat patients. But eve...
      Speaker: Scott Newman, PhD , Clay McLeod
      Sponsored By: DNAnexus
      5
      OCT 11, 2018 | 12:00 PM
      Lung Cancer Evolution and Immune Escape
      Lung Cancer Evolution and Immune Escape
      Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
      Speaker: Nicholas McGranahan, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 10:30 AM
      Drug Targeting for Inflammatory Breast Cancer
      Drug Targeting for Inflammatory Breast Cancer
      Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
      Speaker: Kevin Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 11, 2018 | 7:30 AM
      Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
      Keynote Presentation: In Advanced Cancers Curative Therapies Must...
      In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
      Speaker: Krastan Blagoev, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 8:00 AM
      Tissue Biomarker Analysis: A Practical Approach for Translational Research
      Tissue Biomarker Analysis: A Practical Approach for Translational...
      DATE: October 11, 2018TIME: 8:00AM PDTSimultaneous quantitation of 6 or more biomarkers in intact tissue specimens holds the key to many questions concerning the biological basis o...
      Speaker: Grady Carlson, PhD , Linden Wyatt, PhD
      Sponsored By: Revvity
      6
      OCT 10, 2018 | 1:30 PM
      Discovery of Biomarkers Predictive of Anticancer Drug Response in Preclinical Settings
      Discovery of Biomarkers Predictive of Anticancer Drug Response...
      Some Abstract...
      Speaker: Benjamin Haibe-Kains, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
      Speaker: Jerome Galon, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 10:30 AM
      Metabolic Networks in the Tumor Microenvironment
      Metabolic Networks in the Tumor Microenvironment
      Pancreatic tumors are dynamic pseudo-organs that contain numerous cell types interacting to create unique physiology. A typical pancreatic tumor is made up largely of stromal fibroblasts and...
      Speaker: Costas A. Lyssiotis, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: Agilent
      2
      OCT 10, 2018 | 9:00 AM
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
      In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
      Speaker: Paul Sondel, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 7:30 AM
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
      Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
      Speaker: Karin Rodland, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 10, 2018 | 6:00 AM
      The Role of Vaccination for the Treatment and Prevention of Breast and Ovarian Cancers
      The Role of Vaccination for the Treatment and Prevention of Breast...
      With over 265,000 new cases per year and over 50,000 deaths, breast and ovarian cancers represent a significant health burden in the USA.  Prior work has demonstrated that CD4 helper T c...
      Speaker: Keith Knutson, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      6
      OCT 03, 2018 | 9:00 AM
      Mechanisms of Myeloid Immunosuppression:  Functional Characterization of the Tumor Microenvironment Using Single and Multiplex IHC
      Mechanisms of Myeloid Immunosuppression: Functional Characterization...
      DATE:  October 3, 2018TIME:  9:00am PDT, 12:00pm EDT Infiltrating myeloid cells constitute a significant component of the suppressive tumor microenvironment (TME) a...
      Speaker: Christopher Grange
      Sponsored By: Cell Signaling Technology
      3
    FEB 27, 2019 | 7:30 AM
    Keynote Presentation: Second Harmonic Generation Detection of Ras Conformational Changes and Discovery of a Novel Small-Molecule Binder
    Keynote Presentation: Second Harmonic Generation Detection of...
    Second harmonic generation (SHG) is a biophysical method that sensitively measures real-time conformational change of biomolecules attached to membranes. SHG has recently been applied to dete...
    Speaker: Frank McCormick, PhD
    Presented at: Drug Discovery Virtual Event Series 2019
    1
    JAN 31, 2019 | 7:30 AM
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based Gene Delivery for Targeted Treatment of HER2-Positive Breast Cancer in Mice by Prodrugs - A New Gene-Delivered Enzyme Prodrug
    Keynote Presentation: Extracellular Vesicle-Mediated mRNA-Based...
    Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
    Speaker: A.C. Matin, PhD
    Presented at: BioProcessing Virtual Event Series 2019
    1
    DEC 13, 2018 | 9:00 AM
    Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using Models of Endocrine Resistance
    Optimizing Treatment Options for HER2+/ ER+ Breast Cancer using...
    DATE: December 13 15,2018TIME: 09:00am PST, 12:00pm EST Breast cancers are classified into three main subtypes according to their receptor status: estrogen receptor-positive...
    Speaker: Hillary Stires, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
    NOV 28, 2018 | 7:00 AM
    Discover how single-cell RNA sequencing provides deeper insights into lung cancer biology
    Discover how single-cell RNA sequencing provides deeper insights...
    DATE: November 28, 2018TIME:  7:00AM PSTSingle-cell genomics enables a deep dive into the mechanisms responsible for health and disease, in areas from cancer biology to neurob...
    Speaker: Bernard Thienpont , Annika Branting , Pawel Zajac, Ph.D.
    Sponsored By: Illumina, 10x Genomics
    5
    NOV 15, 2018 | 12:00 PM
    Better Knowledge, Better Care: Precision Medicine for Any Cancer, Any Assay, on Your Platform
    Better Knowledge, Better Care: Precision Medicine for Any Cancer,...
    QIAGEN helps your team focus on the opportunities, not the obstacles, with an end-to-end clinical testing solution. During this talk, we will present a lung cancer case study to show how QIAG...
    Speaker: Raed Samara, PhD , Dan Richards, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
    Sponsored By: QIAGEN
    2
     
     
  • NOV 15, 2018 | 7:00 AM
    Use of stem-cell derived endothelial cells for disease relevant cell modeling and drug discovery
    Use of stem-cell derived endothelial cells for disease relevant...
    The use of human pluripotent stem cells (hPSCs) for in vitro disease-modeling is limited by the lack of robust and efficient protocols for the differentiation of relevant adult cell types. Pr...
    Speaker: Filip Roudnicky
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    8
    NOV 14, 2018 | 9:00 AM
    Accelerating Cancer Research and Clinical Innovations Using OncoLand
    Accelerating Cancer Research and Clinical Innovations Using OncoLand
    With significant decrease in the cost of sequencing in numerous commercial as well as cancer center–driven initiatives, genomic profiling is increasingly becoming routine across multipl...
    Speaker: Bing Zhou, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    NOV 07, 2018 | 8:00 PM
    Analysis of Surface Antigens on Exosomes
    Analysis of Surface Antigens on Exosomes
    DATE: November 7, 2018TIME: 8:00PM PSTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metasta...
    Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
    Sponsored By: Thermo Fisher Scientific
    3 1
    NOV 07, 2018 | 7:00 AM
    Analysis of Surface Antigens on Exosomes
    Analysis of Surface Antigens on Exosomes
    DATE: November 7, 2018TIME: 7:00AM PDTExosomes have been shown to have significant roles in cancer including disease progression acting in the tumor micro-environment, metastasis a...
    Speaker: Steve McClellan BS, MT, SCYM (ASCP)CM
    Sponsored By: Thermo Fisher Scientific
    11 1
    NOV 01, 2018 | 12:00 AM
    Advanced 3D cell models for cancer biology using real time live-cell analysis
    Advanced 3D cell models for cancer biology using real time live-cell...
    Integrated protocols and live-cell analysis solutions for different 3D tumor modelsIn the search for greater clinical translation, cancer researchers are increasingly turning to more comp...
    Speaker: Kalpana Patel
    Presented at: Dimension of Time: From Culture to Assay
    2
     
     
  • NOV 01, 2018 | 12:00 AM
    Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
    Glycosylation and stabilization of programmed death ligand-1 suppresses...
    The success of immune checkpoint blockade adds a new therapeutic category to the cancer therapy repertoire. Despite efforts made on cancer cell and immune cell interaction, how cancer cells i...
    Speaker: Chia-Wei Li, PhD
    Presented at: Dimension of Time: From Culture to Assay
    1
    OCT 25, 2018 | 8:00 AM
    Disease modeling and cancer therapy in stem cell-derived 3D organoid systems
    Disease modeling and cancer therapy in stem cell-derived 3D organoid...
    DATE: October 25, 2018TIME:  08:00am PDT, 11:00am EDT While the significance of the microbiome is unprecedented, a thorough study to dissect the role of individual popul...
    Speaker: Devanjali Dutta, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
    OCT 23, 2018 | 10:00 AM
    Pediatric Cancer Genomics: Accessing Data, Tools and Visualizations in St. Jude Cloud
    Pediatric Cancer Genomics: Accessing Data, Tools and Visualizations...
    DATE: October 23, 2018TIME: 10:00am PDT, 1:00pm EDT Next-generation genomic sequencing is transforming what is known about pediatric cancer and how we treat patients. But eve...
    Speaker: Scott Newman, PhD , Clay McLeod
    Sponsored By: DNAnexus
    5
    OCT 11, 2018 | 12:00 PM
    Lung Cancer Evolution and Immune Escape
    Lung Cancer Evolution and Immune Escape
    Lung cancer is the leading cause of cancer-related mortality worldwide. Large-scale sequencing studies have revealed the complex genomic landscape of NSCLC and genomic differences between lun...
    Speaker: Nicholas McGranahan, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 10:30 AM
    Drug Targeting for Inflammatory Breast Cancer
    Drug Targeting for Inflammatory Breast Cancer
    Two projects looking at novel approaches to targeting inflammatory breast cancer will be presented. Inflammatory breast cancer (IBC) is a unique, understudied, and most lethal subtype account...
    Speaker: Kevin Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
     
     
  • OCT 11, 2018 | 7:30 AM
    Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
    Keynote Presentation: In Advanced Cancers Curative Therapies Must...
    In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    Speaker: Krastan Blagoev, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 8:00 AM
    Tissue Biomarker Analysis: A Practical Approach for Translational Research
    Tissue Biomarker Analysis: A Practical Approach for Translational...
    DATE: October 11, 2018TIME: 8:00AM PDTSimultaneous quantitation of 6 or more biomarkers in intact tissue specimens holds the key to many questions concerning the biological basis o...
    Speaker: Grady Carlson, PhD , Linden Wyatt, PhD
    Sponsored By: Revvity
    6
    OCT 10, 2018 | 1:30 PM
    Discovery of Biomarkers Predictive of Anticancer Drug Response in Preclinical Settings
    Discovery of Biomarkers Predictive of Anticancer Drug Response...
    Some Abstract...
    Speaker: Benjamin Haibe-Kains, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
    Speaker: Jerome Galon, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 10:30 AM
    Metabolic Networks in the Tumor Microenvironment
    Metabolic Networks in the Tumor Microenvironment
    Pancreatic tumors are dynamic pseudo-organs that contain numerous cell types interacting to create unique physiology. A typical pancreatic tumor is made up largely of stromal fibroblasts and...
    Speaker: Costas A. Lyssiotis, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: Agilent
    2
     
     
  • OCT 10, 2018 | 9:00 AM
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
    In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
    Speaker: Paul Sondel, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 7:30 AM
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
    Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
    Speaker: Karin Rodland, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 10, 2018 | 6:00 AM
    The Role of Vaccination for the Treatment and Prevention of Breast and Ovarian Cancers
    The Role of Vaccination for the Treatment and Prevention of Breast...
    With over 265,000 new cases per year and over 50,000 deaths, breast and ovarian cancers represent a significant health burden in the USA.  Prior work has demonstrated that CD4 helper T c...
    Speaker: Keith Knutson, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    6
    OCT 03, 2018 | 9:00 AM
    Mechanisms of Myeloid Immunosuppression:  Functional Characterization of the Tumor Microenvironment Using Single and Multiplex IHC
    Mechanisms of Myeloid Immunosuppression: Functional Characterization...
    DATE:  October 3, 2018TIME:  9:00am PDT, 12:00pm EDT Infiltrating myeloid cells constitute a significant component of the suppressive tumor microenvironment (TME) a...
    Speaker: Christopher Grange
    Sponsored By: Cell Signaling Technology
    3
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