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Focusing on the urgent clinical problem of increasing carbapenem resistance in Enterobacteriaceae we have been evaluating detection methods in clinical microbiology and molecular transmissio...
Respiratory viruses continue to pose significant public health challenges globally, including influenza viruses, coronaviruses etc. While existing vaccines have made substantial progress in...
This talk will describe the role of the clinical lab in advancing health equity. It will define the gaps in equitable access to lab testing and how that impacts patient care. We will also co...
Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
Achieving a diagnosis in rare disease patients can be challenging for even the most experienced clinician or scientist, creating a barrier to delivering truly personalised care. An exome seq...
Image-based high-content screening (HCS) involving cancer cell lines grown in conventional two-dimensional (2D) cell culture, has provided a cornerstone assay for searching new agents to tre...
For infectious disease pathogen detection and research, real-time PCR enables reliable, sensitive, specific, and scalable results over slower culture-based methods...
Imaging offers a means to draw upon the growing body of high-throughput molecular data to better understand the underlying cellular and molecular mechanisms of embryonic development; however...
Over the last few years, the space of advanced in vitro models has grown dramatically as researchers look to better mimic the in vivo environment within inexpensive and high throughput in vi...
The use of medically unsupervised cannabis use is exponentially growing in the USA. Healthcare providers need to not only recognize this fact but embrace it with the goal of avoiding drug-dr...
CRISPR experiments are a powerful tool which are easy to carry out, however it is more difficult to determine the outcome of these experiments, and to ensure that only the desired targets we...
Hepatocellular Carcinoma (HCC) and Endometrioid Endometrial Carcinoma (EEC) are two lethal diseases of public health importance worldwide. Understanding the mechanisms of tumor progression in...
Learning Objectives: 1. What states will begin requiring mandatory testing for cannabis this year? 2. What states have recently changed their testing regulations? What states are looking to...
Lowe Syndrome (LS) is a devastating genetic disease characterized by abnormalities in the eyes, brain and kidneys that unfortunately leads to the premature death of affected children due to r...
Since 1993, Gibco™ B-27™ Supplement and Neurobasal™ Medium has been the trusted standard for a variety of neuronal culture applications, with citations in more than 11,000 p...
Tumor phenotypes are dictated not only by the neoplastic cell component, but also by the tumor microenvironment (TME), which is inherently immuno-suppressive, is equipped to hamper effector...
Over the past five years there has been an explosion of research the deep learning field. Companies like Google, Facebook, and OpenAI have created neural networks that are significantly more...
MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post transcriptional level. They are known to play a critical role in multiple biologi...
In the past years, next-generation sequencing has revolutionized the way testing is done in the field of clinical oncology research. Parallel testing of genomic markers in tissue biopsies as...
Urine drug testing has become an essential part of the management of patients with chronic pain. Testing provides objective information regarding drug compliance, diversion, and abuse to med...
Background: Preimplantation genetic testing for aneuploidy (PGT-A) and structural rearrangement (PGT-SR) have been widely used within indications of previous miscarriages, repeated implantat...
Cortical circuits often receive multiple inputs from upstream populations with non-overlapping stimulus tuning. Both the feedforward and recurrent architectures of the receiving cortical lay...
Moving the needle on legalization, the cannabis industry has seen significant growth in the past year. However, this growth has had its dampeners, such as THC potency inflation and rampant l...
Many commercially promising proteins are difficult-to-express (DTE) in living cells and are lost before an industrial production process can be established. Cell-free protein expression (CFP...
MicroRNAs (miRs) are small non-coding RNAs whose expression is altered in several types of human cancers. Recent evidence supports their inter-cellular transfer through extracellular vesicle...