ADME-Tox
ADME is an abbreviation in pharmacokinetics and pharmacology for "absorption, distribution, metabolism, and excretion". ADME-Tox studies are essential for the drug discovery process, as they can save development costs and time, and reduce the likelihood of failure.
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FEB 26, 2020 1:30 PM PSTC.E. CREDITS
FEB 26, 2020 1:30 PM PSTWhether you are performing killing assays, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery of new therapeutics. Conc...Speaker: Josh Mahlios, PhDPresented at: Drug Discovery & Development 2020Sponsored By: Miltenyi BiotecFEB 26, 2020 12:00 PM PSTC.E. CREDITS
FEB 26, 2020 12:00 PM PSTDigital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...Speaker: Sarah Warren, PhDPresented at: Drug Discovery & Development 2020Sponsored By: NanoString TechnologiesFEB 26, 2020 10:30 AM PSTC.E. CREDITS
FEB 26, 2020 10:30 AM PSTQIAGEN CLC Genomics Workbench is a powerful solution to analyze and visualize next generation sequencing (NGS) data. Powered by cutting-edge technology and accelerated algorithms, it support...Speaker: Leif Schauser, PhDPresented at: Drug Discovery & Development 2020Sponsored By: QIAGENFEB 26, 2020 9:00 AM PSTC.E. CREDITS
FEB 26, 2020 9:00 AM PSTDATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...Speaker: Julia Tritapoe , David Kuninger, PhDSponsored By: Thermo Fisher ScientificFEB 26, 2020 9:00 AM PSTC.E. CREDITS
FEB 26, 2020 9:00 AM PSTCRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...Speaker: Andrew Ravanelli, PhDPresented at: Drug Discovery & Development 2020Sponsored By: MilliporeSigmaFEB 26, 2020 7:30 AM PSTC.E. CREDITS
FEB 26, 2020 7:30 AM PSTRecent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...Speaker: Khyati Shah, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...Speaker: Erin Edwards, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...Speaker: Salman Khetani, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
“The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...Speaker: Rekha Pal, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
Biomarkers are critical tools for all stages of cancer research, from drug development through clinical applications. Cancer is fundamentally a disease of unregulated cell growth and circumv...Speaker: Olivia Stricker, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in developed countries, and it affects over 25% of the population worldwide. Within the next five y...Speaker: Jessica Tuohy, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...Speaker: Chames Kermi, PhD, PharmDPresented at: Drug Discovery & Development 2020C.E. CREDITS
The use of primary cells in vitro is compromised by the limited quantity of cells that can be isolated from one donor, a lack of or very restricted proliferation capacity (e.g. hepatocytes)...Speaker: Astrid Nörenberg, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...Speaker: Sebastiaan Trietsch, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
The aim of the lecture is to give an insight into the use of 3D liver micro tissues (3D liMTs) in drug discovery and translational safety. In translational toxicology, 3D LiMTs have a high i...Speaker: Armin Wolf, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...Speaker: Tomasz Kostrzewski, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
Learning Objectives: 1. Describe the exposure response relationships with vancomycin and acute kidney injury 2. Define biomarkers that may be useful to improve Precision Dosing...Speaker: Marc Scheetz, PharmD, MSc, FCCP, BCPS AQ-IDPresented at: Drug Discovery & Development 2020OCT 29, 2019 7:00 AM PDTC.E. CREDITS
OCT 29, 2019 7:00 AM PDTDATE: October 29, 2019TIME: 7:00am PDT3D cell culture systems have recently emerged as tools for reproducing the cellular environment and the organization of tissues/organs, where cel...Speaker: Elodie Vandenhaute , Zied Souguir , Daniel O'ConnorSponsored By: Molecular DevicesAUG 27, 2019 9:00 AM PDTC.E. CREDITS
AUG 27, 2019 9:00 AM PDTDATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...Speaker: Cliff Hoyt, PhD , Steve LuSponsored By: Akoya BiosciencesJUN 19, 2019 10:00 AM PDT
JUN 19, 2019 10:00 AM PDTDATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...Speaker: Mark Kennedy, Ph.D. , Richard Josephson, PhDSponsored By: Thermo Fisher ScientificAPR 17, 2019 9:00 AM PDTC.E. CREDITS
APR 17, 2019 9:00 AM PDTDATE: April 17, 2019TIME: 9:00am PDT...Speaker: Takanori TakebeSponsored By: Thermo Fisher ScientificAPR 03, 2019 9:00 AM PDTC.E. CREDITS
APR 03, 2019 9:00 AM PDTDATE: April 3, 2019TIME: 9:00am PDT...Speaker: Chris LangsdorfSponsored By: Thermo Fisher ScientificMAR 20, 2019 9:00 AM PDTC.E. CREDITS
MAR 20, 2019 9:00 AM PDTDATE: March 20, 2019TIME: 9:00am PDT...Speaker: Mark Kennedy, Ph.D.Sponsored By: Thermo Fisher ScientificFEB 27, 2019 3:00 PM PSTC.E. CREDITS
FEB 27, 2019 3:00 PM PSTDramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...Speaker: Shivaani Kummar, MD, FACPPresented at: Drug Discovery 2019
FEB 26, 2020
1:30 PM PST
C.E. CREDITS
FEB 26, 2020
1:30 PM PST
Whether you are performing killing assays, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery of new therapeutics. Conc...
Speaker:
Josh Mahlios, PhD
Presented at: Drug Discovery & Development 2020Sponsored By: Miltenyi Biotec
FEB 26, 2020
12:00 PM PST
C.E. CREDITS
FEB 26, 2020
12:00 PM PST
Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
Speaker:
Sarah Warren, PhD
Presented at: Drug Discovery & Development 2020Sponsored By: NanoString Technologies
FEB 26, 2020
10:30 AM PST
C.E. CREDITS
FEB 26, 2020
10:30 AM PST
QIAGEN CLC Genomics Workbench is a powerful solution to analyze and visualize next generation sequencing (NGS) data. Powered by cutting-edge technology and accelerated algorithms, it support...
Speaker:
Leif Schauser, PhD
Presented at: Drug Discovery & Development 2020Sponsored By: QIAGEN
FEB 26, 2020
9:00 AM PST
C.E. CREDITS
FEB 26, 2020
9:00 AM PST
DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
Speaker:
Julia Tritapoe
,
David Kuninger, PhD
Sponsored By: Thermo Fisher Scientific
FEB 26, 2020
9:00 AM PST
C.E. CREDITS
FEB 26, 2020
9:00 AM PST
CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
Speaker:
Andrew Ravanelli, PhD
Presented at: Drug Discovery & Development 2020Sponsored By: MilliporeSigma
FEB 26, 2020
7:30 AM PST
C.E. CREDITS
FEB 26, 2020
7:30 AM PST
Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
Speaker:
Khyati Shah, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...
Speaker:
Erin Edwards, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
Speaker:
Salman Khetani, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
“The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
Speaker:
Rekha Pal, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
Biomarkers are critical tools for all stages of cancer research, from drug development through clinical applications. Cancer is fundamentally a disease of unregulated cell growth and circumv...
Speaker:
Olivia Stricker, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in developed countries, and it affects over 25% of the population worldwide. Within the next five y...
Speaker:
Jessica Tuohy, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
Speaker:
Chames Kermi, PhD, PharmD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
The use of primary cells in vitro is compromised by the limited quantity of cells that can be isolated from one donor, a lack of or very restricted proliferation capacity (e.g. hepatocytes)...
Speaker:
Astrid Nörenberg, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
Speaker:
Sebastiaan Trietsch, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
The aim of the lecture is to give an insight into the use of 3D liver micro tissues (3D liMTs) in drug discovery and translational safety. In translational toxicology, 3D LiMTs have a high i...
Speaker:
Armin Wolf, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
Speaker:
Tomasz Kostrzewski, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
Learning Objectives: 1. Describe the exposure response relationships with vancomycin and acute kidney injury 2. Define biomarkers that may be useful to improve Precision Dosing...
Speaker:
Marc Scheetz, PharmD, MSc, FCCP, BCPS AQ-ID
Presented at: Drug Discovery & Development 2020
OCT 29, 2019
7:00 AM PDT
C.E. CREDITS
OCT 29, 2019
7:00 AM PDT
DATE: October 29, 2019TIME: 7:00am PDT3D cell culture systems have recently emerged as tools for reproducing the cellular environment and the organization of tissues/organs, where cel...
Speaker:
Elodie Vandenhaute
,
Zied Souguir
,
Daniel O'Connor
Sponsored By: Molecular Devices
AUG 27, 2019
9:00 AM PDT
C.E. CREDITS
AUG 27, 2019
9:00 AM PDT
DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
Speaker:
Cliff Hoyt, PhD
,
Steve Lu
Sponsored By: Akoya Biosciences
JUN 19, 2019
10:00 AM PDT
JUN 19, 2019
10:00 AM PDT
DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
Speaker:
Mark Kennedy, Ph.D.
,
Richard Josephson, PhD
Sponsored By: Thermo Fisher Scientific
APR 17, 2019
9:00 AM PDT
C.E. CREDITS
APR 17, 2019
9:00 AM PDT
DATE: April 17, 2019TIME: 9:00am PDT...
Speaker:
Takanori Takebe
Sponsored By: Thermo Fisher Scientific
APR 03, 2019
9:00 AM PDT
C.E. CREDITS
APR 03, 2019
9:00 AM PDT
DATE: April 3, 2019TIME: 9:00am PDT...
Speaker:
Chris Langsdorf
Sponsored By: Thermo Fisher Scientific
MAR 20, 2019
9:00 AM PDT
C.E. CREDITS
MAR 20, 2019
9:00 AM PDT
DATE: March 20, 2019TIME: 9:00am PDT...
Speaker:
Mark Kennedy, Ph.D.
Sponsored By: Thermo Fisher Scientific
FEB 27, 2019
3:00 PM PST
C.E. CREDITS
FEB 27, 2019
3:00 PM PST
Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a giv...
Speaker:
Shivaani Kummar, MD, FACP
Presented at: Drug Discovery 2019
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