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        High-throughput CRISPR editing using the Onyx™ platform identifies essential residues in proteins
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        The inhibitory role of specific macrophages in RCC
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        A new approach of COVID-19 surveillance testing to maximize the identification of asymptomatic patients
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        High-throughput CRISPR editing using the Onyx™ platform identifies essential residues in proteins
      • A novel automated and simultaneous protein/antibody high-throughput purification platform: AmMag and its reusable Magbeads
        A novel automated and simultaneous protein/antibody high-throughput purification platform: AmMag and its reusable Magbeads
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        Uterine B cell dynamics during pregnancy - Immune regulation of the placenta
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        Utilization of Optical Genome Mapping in Detection and Characterization of Rare Genetic Markers in Pediatric Leukemias
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        Endpoint assays for the characterization of rare and therapy-resistant cells in cancer
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    ADME-Tox

    ADME is an abbreviation in pharmacokinetics and pharmacology for "absorption, distribution, metabolism, and excretion". ADME-Tox studies are essential for the drug discovery process, as they can save development costs and time, and reduce the likelihood of failure.

    Webinars

    • NOV 12, 2020 10:00 AM PST
      FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
      NOV 12, 2020 10:00 AM PST
      FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
      Date: November 12, 2020 Time: 10:00am (PST), 1:00pm (EST) Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate anti...
      Speaker: Tilman Schlothauer, Ph.D
      Sponsored By: Roche CustomBiotech
      OCT 01, 2020 10:00 AM PDT
      C.E. CREDITS
      Improvements to Bile Collection Studies in Rats
      OCT 01, 2020 10:00 AM PDT
      Improvements to Bile Collection Studies in Rats
      Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
      Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
      Sponsored By: SAI Infusion Technologies
      C.E. CREDITS
      Estimating the age of biological evidence recovered from a crime scene by assessing RNA degradation in the sample
      Estimating the age of biological evidence recovered from a crime...
      The forensic investigation of crime involves answering four basic questions: who, what, where, and when. Tools exist to answer questions of who, what and where, but the question when is ofte...
      Speaker: Robert W. Allen, PhD
      Presented at: Forensic Sciences 2020
      MAY 06, 2020 9:00 AM PDT
      C.E. CREDITS
      Keynote Presentation: Pattern Evidence Reconstruction
      MAY 06, 2020 9:00 AM PDT
      Keynote Presentation: Pattern Evidence Reconstruction
      Crime scene investigation is more than just processing or documentation of crime scenes, nor is it just the collection or packaging of physical evidence. It is the first step and the most cr...
      Speaker: Henry C. Lee, PhD
      Presented at: Forensic Sciences 2020
      MAY 06, 2020 7:30 AM PDT
      C.E. CREDITS
      Keynote Presentation: Complexities of characterizing mineral particle toxicity at the pulmonary interface
      MAY 06, 2020 7:30 AM PDT
      Keynote Presentation: Complexities of characterizing mineral particle...
      The toxicology of particulate matter is complicated by characteristics not normally encountered when addressing poisonings associated with chemical substances. Particle shape, surface reacti...
      Speaker: Christopher Weis, PhD, DABT
      Presented at: Forensic Sciences 2020
      C.E. CREDITS
      Deciphering the Necrobiome and Postmortem Microbiomes for Use in Forensics
      Deciphering the Necrobiome and Postmortem Microbiomes for Use...
      The necrobiome is the community of organisms that use or are affected by decomposing organic matter. Decomposing organic matter comes in the form of dead plant matter (biomass) or that of de...
      Speaker: M. Eric Benbow, PhD, AAFS-F
      Presented at: Forensic Sciences 2020
      C.E. CREDITS
      Forensic Anthropology At La Línea: Advances In Computational Methods For The Identification Of The U.S.-México Border Dead.
      Forensic Anthropology At La Línea: Advances In Computational Methods...
      The ever-increasing number of deaths along the U.S.-México border and the diversification in the demographic characteristics of the Latin American migrants, who perish in this region,...
      Speaker: Bridget Algee-Hewitt, PhD
      Presented at: Forensic Sciences 2020
      C.E. CREDITS
      New Relevance of Hydroxychloroquine and Chloroquine in Forensic Toxicology
      New Relevance of Hydroxychloroquine and Chloroquine in Forensic...
      Hydroxychloroquine and chloroquine are long-standing antimalarial drugs recently brought into the spotlight as potential treatments for the pandemic-causing coronavirus (SARS-CoV-2). Notable...
      Speaker: Wendy Adams, PhD, F-ABFT
      Presented at: Forensic Sciences 2020
      C.E. CREDITS
      I'm biased, and I know it! What can we learn from cognitive bias research in forensic science?
      I'm biased, and I know it! What can we learn from cognitive bias...
      The potential for cognitive bias in forensic evidence interpretation and crime scene investigation continues to receive attention and debate within forensic and academic communities. Startin...
      Speaker: Niki Osborne, PhD
      Presented at: Forensic Sciences 2020
      C.E. CREDITS
      The use of massively parallel sequencing in Forensic DNA typing - what will the future hold?
      The use of massively parallel sequencing in Forensic DNA typing...
      The current standard methodology in forensic DNA typing relies on amplification of short tandem repeat (STR) markers by the polymerase chain reaction (PCR) and allele sizes (i.e., length-bas...
      Speaker: Nicole M.M. Novroski, PhD
      Presented at: Forensic Sciences 2020
      C.E. CREDITS
      Probabilistic genotyping and the power of modern DNA technology: A case study in overturning a wrongful conviction for murder in Texas
      Probabilistic genotyping and the power of modern DNA technology:...
      In late 2019, nearly a decade into a life sentence, Lydell Grant was released from a Texas prison after being convicted of a murder that he did not commit. The victim, Aaron Scheerhorn, was...
      Speaker: Angie Ambers, PhD
      Presented at: Forensic Sciences 2020
      C.E. CREDITS
      Microhaplotypes: the next generation DNA marker
      Microhaplotypes: the next generation DNA marker
      Learning Objectives: 1. Molecular basis of microhaplotypes 2. Informativeness and power of discrimination of microhaplotypes 3. Mixture deconvolution via microhaplotypes...
      Speaker: Daniele Podini
      Presented at: Forensic Sciences 2020
      FEB 26, 2020 1:30 PM PST
      C.E. CREDITS
      Automated cell separation for drug discovery assays
      FEB 26, 2020 1:30 PM PST
      Automated cell separation for drug discovery assays
      Whether you are performing killing assays, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery of new therapeutics. Conc...
      Speaker: Josh Mahlios, PhD
      Presented at: Drug Discovery & Development 2020Sponsored By: Miltenyi Biotec
      FEB 26, 2020 12:00 PM PST
      C.E. CREDITS
      Characterizing the role of B cells in Response to Immunotherapy with the NanoString GeoMx Platform
      FEB 26, 2020 12:00 PM PST
      Characterizing the role of B cells in Response to Immunotherapy...
      Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
      Speaker: Sarah Warren, PhD
      Presented at: Drug Discovery & Development 2020Sponsored By: NanoString Technologies
      FEB 26, 2020 10:30 AM PST
      C.E. CREDITS
      QIAGEN CLC Genomics Workbench 20 - scalable software for NGS data analysis
      FEB 26, 2020 10:30 AM PST
      QIAGEN CLC Genomics Workbench 20 - scalable software for NGS data...
      QIAGEN CLC Genomics Workbench is a powerful solution to analyze and visualize next generation sequencing (NGS) data. Powered by cutting-edge technology and accelerated algorithms, it support...
      Speaker: Leif Schauser, PhD
      Presented at: Drug Discovery & Development 2020Sponsored By: QIAGEN
      FEB 26, 2020 9:00 AM PST
      C.E. CREDITS
      The use of 3D Models in Hepatic Biology
      FEB 26, 2020 9:00 AM PST
      The use of 3D Models in Hepatic Biology
      DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
      Speaker: Julia Tritapoe , David Kuninger, PhD
      Sponsored By: Thermo Fisher Scientific
      FEB 26, 2020 9:00 AM PST
      C.E. CREDITS
      CRISPR Based Screening: Advantages of Transcriptional Activators and Inhibitors
      FEB 26, 2020 9:00 AM PST
      CRISPR Based Screening: Advantages of Transcriptional Activators...
      CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Drug Discovery & Development 2020Sponsored By: MilliporeSigma
      FEB 26, 2020 7:30 AM PST
      C.E. CREDITS
      Keynote Presentation: Emerging Drug Combinations: Evolution From Pre-Clinical Discovery to Clinical Development
      FEB 26, 2020 7:30 AM PST
      Keynote Presentation: Emerging Drug Combinations: Evolution From...
      Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
      Speaker: Khyati Shah, PhD
      Presented at: Drug Discovery & Development 2020
      C.E. CREDITS
      Using 3D cell culture models and high content confocal imaging to evaluate efficacy and expose toxic liabilities in the drug development pipeline
      Using 3D cell culture models and high content confocal imaging...
      With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...
      Speaker: Erin Edwards, PhD
      Presented at: Drug Discovery & Development 2020
      C.E. CREDITS
      Microfabricated Human Liver Tissues for Drug Development
      Microfabricated Human Liver Tissues for Drug Development
      The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
      Speaker: Salman Khetani, PhD
      Presented at: Drug Discovery & Development 2020
      C.E. CREDITS
      Organoids: A Revolutionary New Tool for Drug Screening
      Organoids: A Revolutionary New Tool for Drug Screening
      “The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
      Speaker: Rekha Pal, PhD
      Presented at: Drug Discovery & Development 2020
      C.E. CREDITS
      Measuring What Matters:  Proliferation and Cell Death Biomarkers for Oncology Research
      Measuring What Matters: Proliferation and Cell Death Biomarkers...
      Biomarkers are critical tools for all stages of cancer research, from drug development through clinical applications. Cancer is fundamentally a disease of unregulated cell growth and circumv...
      Speaker: Olivia Stricker, PhD
      Presented at: Drug Discovery & Development 2020
      C.E. CREDITS
      CK18 as a Biomarker in NASH Clinical Trials
      CK18 as a Biomarker in NASH Clinical Trials
      Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in developed countries, and it affects over 25% of the population worldwide. Within the next five y...
      Speaker: Jessica Tuohy, PhD
      Presented at: Drug Discovery & Development 2020
      C.E. CREDITS
      Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
      Uncovering the mechanism of stress-resistant DNA replication in...
      Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
      Speaker: Chames Kermi, PhD, PharmD
      Presented at: Drug Discovery & Development 2020
    NOV 12, 2020 10:00 AM PST
    FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
    NOV 12, 2020 10:00 AM PST
    FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
    Date: November 12, 2020 Time: 10:00am (PST), 1:00pm (EST) Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate anti...
    Speaker: Tilman Schlothauer, Ph.D
    Sponsored By: Roche CustomBiotech
    OCT 01, 2020 10:00 AM PDT
    C.E. CREDITS
    Improvements to Bile Collection Studies in Rats
    OCT 01, 2020 10:00 AM PDT
    Improvements to Bile Collection Studies in Rats
    Date: October 10, 2020 Time: 10:00am (PDT), 1:00pm (EDT) Rodent bile collection studies can be challenging. Not only do they require a technically difficult surgery, but there is also a lear...
    Speaker: Merryl Cramer , Brad Gien, BSc. CM , Gina Ma
    Sponsored By: SAI Infusion Technologies
    C.E. CREDITS
    Estimating the age of biological evidence recovered from a crime scene by assessing RNA degradation in the sample
    Estimating the age of biological evidence recovered from a crime...
    The forensic investigation of crime involves answering four basic questions: who, what, where, and when. Tools exist to answer questions of who, what and where, but the question when is ofte...
    Speaker: Robert W. Allen, PhD
    Presented at: Forensic Sciences 2020
    MAY 06, 2020 9:00 AM PDT
    C.E. CREDITS
    Keynote Presentation: Pattern Evidence Reconstruction
    MAY 06, 2020 9:00 AM PDT
    Keynote Presentation: Pattern Evidence Reconstruction
    Crime scene investigation is more than just processing or documentation of crime scenes, nor is it just the collection or packaging of physical evidence. It is the first step and the most cr...
    Speaker: Henry C. Lee, PhD
    Presented at: Forensic Sciences 2020
    MAY 06, 2020 7:30 AM PDT
    C.E. CREDITS
    Keynote Presentation: Complexities of characterizing mineral particle toxicity at the pulmonary interface
    MAY 06, 2020 7:30 AM PDT
    Keynote Presentation: Complexities of characterizing mineral particle...
    The toxicology of particulate matter is complicated by characteristics not normally encountered when addressing poisonings associated with chemical substances. Particle shape, surface reacti...
    Speaker: Christopher Weis, PhD, DABT
    Presented at: Forensic Sciences 2020
     
     
  • C.E. CREDITS
    Deciphering the Necrobiome and Postmortem Microbiomes for Use in Forensics
    Deciphering the Necrobiome and Postmortem Microbiomes for Use...
    The necrobiome is the community of organisms that use or are affected by decomposing organic matter. Decomposing organic matter comes in the form of dead plant matter (biomass) or that of de...
    Speaker: M. Eric Benbow, PhD, AAFS-F
    Presented at: Forensic Sciences 2020
    C.E. CREDITS
    Forensic Anthropology At La Línea: Advances In Computational Methods For The Identification Of The U.S.-México Border Dead.
    Forensic Anthropology At La Línea: Advances In Computational Methods...
    The ever-increasing number of deaths along the U.S.-México border and the diversification in the demographic characteristics of the Latin American migrants, who perish in this region,...
    Speaker: Bridget Algee-Hewitt, PhD
    Presented at: Forensic Sciences 2020
    C.E. CREDITS
    New Relevance of Hydroxychloroquine and Chloroquine in Forensic Toxicology
    New Relevance of Hydroxychloroquine and Chloroquine in Forensic...
    Hydroxychloroquine and chloroquine are long-standing antimalarial drugs recently brought into the spotlight as potential treatments for the pandemic-causing coronavirus (SARS-CoV-2). Notable...
    Speaker: Wendy Adams, PhD, F-ABFT
    Presented at: Forensic Sciences 2020
    C.E. CREDITS
    I'm biased, and I know it! What can we learn from cognitive bias research in forensic science?
    I'm biased, and I know it! What can we learn from cognitive bias...
    The potential for cognitive bias in forensic evidence interpretation and crime scene investigation continues to receive attention and debate within forensic and academic communities. Startin...
    Speaker: Niki Osborne, PhD
    Presented at: Forensic Sciences 2020
    C.E. CREDITS
    The use of massively parallel sequencing in Forensic DNA typing - what will the future hold?
    The use of massively parallel sequencing in Forensic DNA typing...
    The current standard methodology in forensic DNA typing relies on amplification of short tandem repeat (STR) markers by the polymerase chain reaction (PCR) and allele sizes (i.e., length-bas...
    Speaker: Nicole M.M. Novroski, PhD
    Presented at: Forensic Sciences 2020
     
     
  • C.E. CREDITS
    Probabilistic genotyping and the power of modern DNA technology: A case study in overturning a wrongful conviction for murder in Texas
    Probabilistic genotyping and the power of modern DNA technology:...
    In late 2019, nearly a decade into a life sentence, Lydell Grant was released from a Texas prison after being convicted of a murder that he did not commit. The victim, Aaron Scheerhorn, was...
    Speaker: Angie Ambers, PhD
    Presented at: Forensic Sciences 2020
    C.E. CREDITS
    Microhaplotypes: the next generation DNA marker
    Microhaplotypes: the next generation DNA marker
    Learning Objectives: 1. Molecular basis of microhaplotypes 2. Informativeness and power of discrimination of microhaplotypes 3. Mixture deconvolution via microhaplotypes...
    Speaker: Daniele Podini
    Presented at: Forensic Sciences 2020
    FEB 26, 2020 1:30 PM PST
    C.E. CREDITS
    Automated cell separation for drug discovery assays
    FEB 26, 2020 1:30 PM PST
    Automated cell separation for drug discovery assays
    Whether you are performing killing assays, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery of new therapeutics. Conc...
    Speaker: Josh Mahlios, PhD
    Presented at: Drug Discovery & Development 2020Sponsored By: Miltenyi Biotec
    FEB 26, 2020 12:00 PM PST
    C.E. CREDITS
    Characterizing the role of B cells in Response to Immunotherapy with the NanoString GeoMx Platform
    FEB 26, 2020 12:00 PM PST
    Characterizing the role of B cells in Response to Immunotherapy...
    Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
    Speaker: Sarah Warren, PhD
    Presented at: Drug Discovery & Development 2020Sponsored By: NanoString Technologies
    FEB 26, 2020 10:30 AM PST
    C.E. CREDITS
    QIAGEN CLC Genomics Workbench 20 - scalable software for NGS data analysis
    FEB 26, 2020 10:30 AM PST
    QIAGEN CLC Genomics Workbench 20 - scalable software for NGS data...
    QIAGEN CLC Genomics Workbench is a powerful solution to analyze and visualize next generation sequencing (NGS) data. Powered by cutting-edge technology and accelerated algorithms, it support...
    Speaker: Leif Schauser, PhD
    Presented at: Drug Discovery & Development 2020Sponsored By: QIAGEN
     
     
  • FEB 26, 2020 9:00 AM PST
    C.E. CREDITS
    The use of 3D Models in Hepatic Biology
    FEB 26, 2020 9:00 AM PST
    The use of 3D Models in Hepatic Biology
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    Speaker: Julia Tritapoe , David Kuninger, PhD
    Sponsored By: Thermo Fisher Scientific
    FEB 26, 2020 9:00 AM PST
    C.E. CREDITS
    CRISPR Based Screening: Advantages of Transcriptional Activators and Inhibitors
    FEB 26, 2020 9:00 AM PST
    CRISPR Based Screening: Advantages of Transcriptional Activators...
    CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Drug Discovery & Development 2020Sponsored By: MilliporeSigma
    FEB 26, 2020 7:30 AM PST
    C.E. CREDITS
    Keynote Presentation: Emerging Drug Combinations: Evolution From Pre-Clinical Discovery to Clinical Development
    FEB 26, 2020 7:30 AM PST
    Keynote Presentation: Emerging Drug Combinations: Evolution From...
    Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
    Speaker: Khyati Shah, PhD
    Presented at: Drug Discovery & Development 2020
    C.E. CREDITS
    Using 3D cell culture models and high content confocal imaging to evaluate efficacy and expose toxic liabilities in the drug development pipeline
    Using 3D cell culture models and high content confocal imaging...
    With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...
    Speaker: Erin Edwards, PhD
    Presented at: Drug Discovery & Development 2020
    C.E. CREDITS
    Microfabricated Human Liver Tissues for Drug Development
    Microfabricated Human Liver Tissues for Drug Development
    The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
    Speaker: Salman Khetani, PhD
    Presented at: Drug Discovery & Development 2020
     
     
  • C.E. CREDITS
    Organoids: A Revolutionary New Tool for Drug Screening
    Organoids: A Revolutionary New Tool for Drug Screening
    “The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
    Speaker: Rekha Pal, PhD
    Presented at: Drug Discovery & Development 2020
    C.E. CREDITS
    Measuring What Matters:  Proliferation and Cell Death Biomarkers for Oncology Research
    Measuring What Matters: Proliferation and Cell Death Biomarkers...
    Biomarkers are critical tools for all stages of cancer research, from drug development through clinical applications. Cancer is fundamentally a disease of unregulated cell growth and circumv...
    Speaker: Olivia Stricker, PhD
    Presented at: Drug Discovery & Development 2020
    C.E. CREDITS
    CK18 as a Biomarker in NASH Clinical Trials
    CK18 as a Biomarker in NASH Clinical Trials
    Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in developed countries, and it affects over 25% of the population worldwide. Within the next five y...
    Speaker: Jessica Tuohy, PhD
    Presented at: Drug Discovery & Development 2020
    C.E. CREDITS
    Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
    Uncovering the mechanism of stress-resistant DNA replication in...
    Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
    Speaker: Chames Kermi, PhD, PharmD
    Presented at: Drug Discovery & Development 2020
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