ADME
ADME: an abbreviation in pharmacokinetics and pharmacology for "absorption, distribution, metabolism, and excretion," which describes the disposition of a pharmaceutical compound within an organism. The four criteria all influence the drug levels and kinetics of drug exposure to the tissues and hence influence the performance and pharmacological activity of the compound as a drug.
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APR 15, 2020 4:00 PM CESTC.E. CREDITS
APR 15, 2020 4:00 PM CESTDATE: April 15, 2020 TIME: 4:00pm CEST, 07:00am PT, 010:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...FEB 26, 2020 1:30 PM PSTC.E. CREDITS
FEB 26, 2020 1:30 PM PSTWhether you are performing killing assays, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery of new therapeutics. Conc...Speaker: Josh Mahlios, PhDPresented at: Drug Discovery & Development 2020Sponsored By: Miltenyi BiotecFEB 26, 2020 12:00 PM PSTC.E. CREDITS
FEB 26, 2020 12:00 PM PSTDigital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...Speaker: Sarah Warren, PhDPresented at: Drug Discovery & Development 2020Sponsored By: NanoString TechnologiesFEB 26, 2020 10:30 AM PSTC.E. CREDITS
FEB 26, 2020 10:30 AM PSTQIAGEN CLC Genomics Workbench is a powerful solution to analyze and visualize next generation sequencing (NGS) data. Powered by cutting-edge technology and accelerated algorithms, it support...Speaker: Leif Schauser, PhDPresented at: Drug Discovery & Development 2020Sponsored By: QIAGENFEB 26, 2020 9:00 AM PSTC.E. CREDITS
FEB 26, 2020 9:00 AM PSTDATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...Speaker: Julia Tritapoe , David Kuninger, PhDSponsored By: Thermo Fisher ScientificFEB 26, 2020 9:00 AM PSTC.E. CREDITS
FEB 26, 2020 9:00 AM PSTCRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...Speaker: Andrew Ravanelli, PhDPresented at: Drug Discovery & Development 2020Sponsored By: MilliporeSigmaFEB 26, 2020 7:30 AM PSTC.E. CREDITS
FEB 26, 2020 7:30 AM PSTRecent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...Speaker: Khyati Shah, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...Speaker: Erin Edwards, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...Speaker: Salman Khetani, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
“The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...Speaker: Rekha Pal, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
Biomarkers are critical tools for all stages of cancer research, from drug development through clinical applications. Cancer is fundamentally a disease of unregulated cell growth and circumv...Speaker: Olivia Stricker, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in developed countries, and it affects over 25% of the population worldwide. Within the next five y...Speaker: Jessica Tuohy, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...Speaker: Chames Kermi, PhD, PharmDPresented at: Drug Discovery & Development 2020C.E. CREDITS
The use of primary cells in vitro is compromised by the limited quantity of cells that can be isolated from one donor, a lack of or very restricted proliferation capacity (e.g. hepatocytes)...Speaker: Astrid Nörenberg, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...Speaker: Sebastiaan Trietsch, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
The aim of the lecture is to give an insight into the use of 3D liver micro tissues (3D liMTs) in drug discovery and translational safety. In translational toxicology, 3D LiMTs have a high i...Speaker: Armin Wolf, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...Speaker: Tomasz Kostrzewski, PhDPresented at: Drug Discovery & Development 2020C.E. CREDITS
Learning Objectives: 1. Describe the exposure response relationships with vancomycin and acute kidney injury 2. Define biomarkers that may be useful to improve Precision Dosing...Speaker: Marc Scheetz, PharmD, MSc, FCCP, BCPS AQ-IDPresented at: Drug Discovery & Development 2020DEC 04, 2019 7:00 AM PSTC.E. CREDITS
DEC 04, 2019 7:00 AM PSTDATE: December 4, 2019TIME: 7:00am PST, 10:00am EST, 4:00pm CET Do you know how it feels when you just quickly want to redo an experiment that your colleague did, or an experim...Speaker: Katja Baesler, PhD , Ulrike Gast, PhD , Alisa GruschkaSponsored By: EppendorfNOV 18, 2019 7:00 AM PSTC.E. CREDITS
NOV 18, 2019 7:00 AM PSTDATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...Speaker: Nadine Mellies, PhD , Katja Baesler, PhDSponsored By: EppendorfSEP 10, 2019 3:00 PM CESTC.E. CREDITS
SEP 10, 2019 3:00 PM CESTDATE: September 10, 2019 TIME: 3:00pm CEST, 06:00am PT, 09:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be...AUG 27, 2019 9:00 AM PDTC.E. CREDITS
AUG 27, 2019 9:00 AM PDTDATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...Speaker: Cliff Hoyt, PhD , Steve LuSponsored By: Akoya BiosciencesAUG 22, 2019 10:30 AM PDTC.E. CREDITS
AUG 22, 2019 10:30 AM PDTDNA profiling tools to teach undergraduate students about forensics generally utilize the PV92 Alu and D1S80 VNTR markers, but are both limited in scope. In contrast, advanced profiling syste...Speaker: David Kass, PhDPresented at: Forensics & Toxicology 2019AUG 22, 2019 9:00 AM PDTC.E. CREDITS
AUG 22, 2019 9:00 AM PDTContemporary law enforcement has greatly expanded its ability to solve crimes by the adoption of advanced forensic techniques, electronic monitoring and new approaches in crime scene procedur...Speaker: Henry C. Lee, PhDPresented at: Forensics & Toxicology 2019
APR 15, 2020
4:00 PM CEST
C.E. CREDITS
APR 15, 2020
4:00 PM CEST
DATE: April 15, 2020 TIME: 4:00pm CEST, 07:00am PT, 010:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be a very important aspect of...
FEB 26, 2020
1:30 PM PST
C.E. CREDITS
FEB 26, 2020
1:30 PM PST
Whether you are performing killing assays, characterizing the tumor microenvironment, or investigating immunogenicity, primary cells are essential for the discovery of new therapeutics. Conc...
Speaker:
Josh Mahlios, PhD
Presented at: Drug Discovery & Development 2020Sponsored By: Miltenyi Biotec
FEB 26, 2020
12:00 PM PST
C.E. CREDITS
FEB 26, 2020
12:00 PM PST
Digital spatial profiling (DSP) on the NanoString GeoMx platform enables high plex molecular profiling of clinical tissue samples. This new profiling strategy enables deep insights into the...
Speaker:
Sarah Warren, PhD
Presented at: Drug Discovery & Development 2020Sponsored By: NanoString Technologies
FEB 26, 2020
10:30 AM PST
C.E. CREDITS
FEB 26, 2020
10:30 AM PST
QIAGEN CLC Genomics Workbench is a powerful solution to analyze and visualize next generation sequencing (NGS) data. Powered by cutting-edge technology and accelerated algorithms, it support...
Speaker:
Leif Schauser, PhD
Presented at: Drug Discovery & Development 2020Sponsored By: QIAGEN
FEB 26, 2020
9:00 AM PST
C.E. CREDITS
FEB 26, 2020
9:00 AM PST
DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
Speaker:
Julia Tritapoe
,
David Kuninger, PhD
Sponsored By: Thermo Fisher Scientific
FEB 26, 2020
9:00 AM PST
C.E. CREDITS
FEB 26, 2020
9:00 AM PST
CRISPR revolutionized gene editing, but multi-target screening remains a complex goal. In addition, the fast pace of CRISPR technology development has brought sophisticated options for libra...
Speaker:
Andrew Ravanelli, PhD
Presented at: Drug Discovery & Development 2020Sponsored By: MilliporeSigma
FEB 26, 2020
7:30 AM PST
C.E. CREDITS
FEB 26, 2020
7:30 AM PST
Recent advances in DNA sequencing and omics-based capabilities are revealing incredible therapeutic opportunities and quickly transforming drug discovery. Molecularly targeted drugs aim to e...
Speaker:
Khyati Shah, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
With an increasing push to improve safety, efficacy, and efficiency throughout the drug development pipeline, researchers are evermore looking to improve the predictive capacity of their in...
Speaker:
Erin Edwards, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
The liver plays a critical role in the metabolism and clearance of more than 70% of marketed drugs. Furthermore, toxicity to the liver is a major reason for preclinical and clinical drug fai...
Speaker:
Salman Khetani, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
“The poor translatability of early-stage preclinical models is a major setback in oncology drug development. Immortalized cell lines, that are extensively used in drug screens, undergo...
Speaker:
Rekha Pal, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
Biomarkers are critical tools for all stages of cancer research, from drug development through clinical applications. Cancer is fundamentally a disease of unregulated cell growth and circumv...
Speaker:
Olivia Stricker, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease in developed countries, and it affects over 25% of the population worldwide. Within the next five y...
Speaker:
Jessica Tuohy, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
Speaker:
Chames Kermi, PhD, PharmD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
The use of primary cells in vitro is compromised by the limited quantity of cells that can be isolated from one donor, a lack of or very restricted proliferation capacity (e.g. hepatocytes)...
Speaker:
Astrid Nörenberg, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
The OrganoPlate is a microtiterplate based Organ-on-a-Chip platform for high throughput drug safety and efficacy screening. It contains up to 96 cell culture chambers that allow co-culture o...
Speaker:
Sebastiaan Trietsch, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
The aim of the lecture is to give an insight into the use of 3D liver micro tissues (3D liMTs) in drug discovery and translational safety. In translational toxicology, 3D LiMTs have a high i...
Speaker:
Armin Wolf, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
Microphysiological systems (MPS), also known as organ-on-chips, are small scale in vitro cell cultures which mimic facets of tissue or organ level function. MPS frequently utilise primary hu...
Speaker:
Tomasz Kostrzewski, PhD
Presented at: Drug Discovery & Development 2020
C.E. CREDITS
Learning Objectives: 1. Describe the exposure response relationships with vancomycin and acute kidney injury 2. Define biomarkers that may be useful to improve Precision Dosing...
Speaker:
Marc Scheetz, PharmD, MSc, FCCP, BCPS AQ-ID
Presented at: Drug Discovery & Development 2020
DEC 04, 2019
7:00 AM PST
C.E. CREDITS
DEC 04, 2019
7:00 AM PST
DATE: December 4, 2019TIME: 7:00am PST, 10:00am EST, 4:00pm CET Do you know how it feels when you just quickly want to redo an experiment that your colleague did, or an experim...
Speaker:
Katja Baesler, PhD
,
Ulrike Gast, PhD
,
Alisa Gruschka
Sponsored By: Eppendorf
NOV 18, 2019
7:00 AM PST
C.E. CREDITS
NOV 18, 2019
7:00 AM PST
DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
Speaker:
Nadine Mellies, PhD
,
Katja Baesler, PhD
Sponsored By: Eppendorf
SEP 10, 2019
3:00 PM CEST
C.E. CREDITS
SEP 10, 2019
3:00 PM CEST
DATE: September 10, 2019 TIME: 3:00pm CEST, 06:00am PT, 09:00am ET The assessment of cell health and cellular responses after experimental manipulation continue to be...
AUG 27, 2019
9:00 AM PDT
C.E. CREDITS
AUG 27, 2019
9:00 AM PDT
DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
Speaker:
Cliff Hoyt, PhD
,
Steve Lu
Sponsored By: Akoya Biosciences
AUG 22, 2019
10:30 AM PDT
C.E. CREDITS
AUG 22, 2019
10:30 AM PDT
DNA profiling tools to teach undergraduate students about forensics generally utilize the PV92 Alu and D1S80 VNTR markers, but are both limited in scope. In contrast, advanced profiling syste...
Speaker:
David Kass, PhD
Presented at: Forensics & Toxicology 2019
AUG 22, 2019
9:00 AM PDT
C.E. CREDITS
AUG 22, 2019
9:00 AM PDT
Contemporary law enforcement has greatly expanded its ability to solve crimes by the adoption of advanced forensic techniques, electronic monitoring and new approaches in crime scene procedur...
Speaker:
Henry C. Lee, PhD
Presented at: Forensics & Toxicology 2019
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