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    Animal disease model development

    Animal disease models are non-human animals used to research strategies to detect, prevent, or treat human disease. A variety of animals, including mice, rats, rabbits, and non-human primates are used for animal disease modeling. New animal disease models are developed regularly as knowledge of disease expand and technological improvements enhance current models.

    Webinars

    • OCT 11, 2017 | 6:00 AM
      Cancer Chemotherapy and the tools needed to Advance Treatment in a Diverse Racial Population
      Cancer Chemotherapy and the tools needed to Advance Treatment...
      Colorectal  cancer  (CRC)  is  the  third  most  commonly  diagnosed  cancer  and  is  the  third leading  cause of  ...
      Speaker: Jennie Williams, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
      1
      SEP 28, 2017 | 9:00 AM
      Fine tuning of myosin activity shapes actomyosin network organization and tissue contractility of the C. elegans spermatheca
      Fine tuning of myosin activity shapes actomyosin network organization...
      Contractile non-muscle cells, including smooth muscle and myoepithelial cells, provide the mechanical forces required for tissue homeostasis in numerous organ systems. For example, smooth mus...
      Speaker: Alison Wirshing, PhD
      Presented at: Cell Biology Virtual Event Series 2017
      1
      SEP 13, 2017 | 9:00 AM
      Insights into virus replication: the role of co-opted host proteins and lipids
      Insights into virus replication: the role of co-opted host proteins...
      Virus – host interactions are currently among the most intensively studied research areas due to the promising new antiviral approaches emerging from these studies. Indeed, RNA viruses,...
      Speaker: Peter L. Nagy, MD., PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      3
      SEP 13, 2017 | 6:00 AM
      Next-generation probiotics targeting C. difficile infection
      Next-generation probiotics targeting C. difficile infection
      Adjunct probiotic therapy has the potential to decrease Clostridium difficile disease incidence and severity. After screening several potential probiotic bacteria for intrinsic resistance to...
      Speaker: Jennifer Spinler, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      1
      SEP 06, 2017 | 9:00 AM
      WEBINAR: Manufacturing and characterization of therapeutic exosomes for clinical studies
      WEBINAR: Manufacturing and characterization of therapeutic exosomes...
      DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
      Speaker: Travis Antes, PhD
      Sponsored By: Miltenyi Biotec
      9
      JUL 01, 2017 | 12:00 AM
      Physiological Oxygen: Historical and Molecular Perspective for Stem Cell Culture
      Physiological Oxygen: Historical and Molecular Perspective for...
      For many decades, cell lines have been cultured in standard CO2 incubators at “normal” atmospheric oxygen concentrations of about 21%. But oxygen concentrations in the human or an...
      Speaker: Mary Kay Bates, M.S.
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      JUL 01, 2017 | 12:00 AM
      New Tools for improved CRISPR gene-editing in stem cells
      New Tools for improved CRISPR gene-editing in stem cells
      The development of the CRISPR/Cas9 gene-editing platform enables the rapid generation of new genetically modified stem cell models of human diseases, as well as providing new potential therap...
      Speaker: James Kehler VMD, PhD
      Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
      2
      JUN 07, 2017 | 9:00 AM
      WEBINAR: Generation of purified human iPSC derived cardiomyocytes using clinically relevant workflow
      WEBINAR: Generation of purified human iPSC derived cardiomyocytes...
      DATE: June 7, 2017TIME: 9:00AM PDT, 12:00PM EDTPluripotent stem cells (PSCs) offer an unlimited source of human cardiovascular cells for research and the development of cardiac regenera...
      Speaker: Todd Herron, BS, PhD
      Sponsored By: Miltenyi Biotec
      5 1
      APR 19, 2017 | 4:00 AM
      WEBINAR: Patient Derived Micro Tumor systems: Future Trends towards improved testing systems
      WEBINAR: Patient Derived Micro Tumor systems: Future Trends towards...
      DATE: April 20th, 2017TIME: 10:00AM SGT, 11:00AM KST, 12:00PM AEST, 2:00PM NZSTWith increasing breadth and depth of genomics studies across a range of cancers, it is now apparent that t...
      Speaker: Giridharan Periyasamy, PhD
      Sponsored By: Revvity
      8
      MAR 15, 2017 | 7:30 AM
      Exercise Targeting Neuroplasticity in Parkinson's disease
      Exercise Targeting Neuroplasticity in Parkinson's disease
      Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
      Speaker: Giselle Petzinger, MD
      Presented at: Neuroscience Virtual Event Series 2017
      2
      FEB 23, 2017 | 12:00 PM
      Recent progress in cellular medicine with an eye to precision medicine
      Recent progress in cellular medicine with an eye to precision...
      Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
      Speaker: Giacinto Scoles, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      2
      FEB 09, 2017 | 3:00 PM
      Education/Training/CPD from the Chinese perspective
      Education/Training/CPD from the Chinese perspective
      DATE: February 9, 2017TIME: 3:00pm PT, 6:00pm ETThe presentation will very briefly cover the regulatory system for lab animals in China, as well as the regulations and guidelines a...
      Speaker: Wanyong (William) Pang, BVM, MS, PhD, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      2
      FEB 09, 2017 | 10:30 AM
      Combining practical training with virtual training in the continuous development of lab animal vets
      Combining practical training with virtual training in the continuous...
      DATE: February 9, 2017TIME: 10:30am PT, 1:30pm ETDuring the last 50 years the claims for continuous development and training of laboratory animal staff has been progressively devel...
      Speaker: Axel Kornerup Hansen, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      4
      FEB 09, 2017 | 9:00 AM
      Improved decision making in the drug discovery process using an innovative approach to modelling chronic liver disease
      Improved decision making in the drug discovery process using an...
      DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETTraditional models of liver fibrosis in rodents involve many weeks of induction, with frequent injections of a pro-fibrotic agent. The m...
      Speaker: Steve England, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      2
      FEB 09, 2017 | 6:00 AM
      Continuous Professional Development (CPD) in Laboratory Animal Science, a continuous improvement in animal welfare and science
      Continuous Professional Development (CPD) in Laboratory Animal...
      DATE: February 9, 2017TIME: 6:00am PT, 9:00am ETThere is no professional area in which CPD is more necessary than in the field of laboratory animals. The continuous advancement of scien...
      Speaker: Patri Vergara, DVM, PhD, DipECLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      3
      FEB 08, 2017 | 3:00 PM
      Management of a research colony of woodchucks (Marmota monax)
      Management of a research colony of woodchucks (Marmota monax)
      DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETThe Eastern woodchuck (Marmota monax) is a large, burrowing rodent with native territories throughout parts of the US and Canada. Woodchu...
      Speaker: Margaret (Peg) Batchelder, DVM, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      2
      FEB 08, 2017 | 3:00 PM
      Alternative Delivery Methods for Post-Operative Analgesia Using Meloxicam in Mice
      Alternative Delivery Methods for Post-Operative Analgesia Using...
      DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETMeloxicam is an analgesic NSAID commonly used in mice. Anecdotal evidence supports the use of alternative delivery methods for analgesics...
      Speaker: Angela Mexas, DVM, PhD, DACVIM, DACLAM , CJ Doane, DVM, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      3 1
      FEB 08, 2017 | 1:30 PM
      Characterization of Niemann Pick Type C mutant mice using automated cage monitoring systems
      Characterization of Niemann Pick Type C mutant mice using automated...
      DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
      Speaker: Sangeetha Iyer, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      1
      FEB 08, 2017 | 12:00 PM
      Availability and Management of Genetically Engineered Swine Models for Biomedical Research
      Availability and Management of Genetically Engineered Swine Models...
      DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETLarge animal models have recently become a staple in biomedical research.  The pig’s similarities to humans in terms of genet...
      Speaker: Eric Walters, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      2
      FEB 08, 2017 | 10:30 AM
      Biosecurity, Reproductive and Social Management of Cat Research Colonies
      Biosecurity, Reproductive and Social Management of Cat Research...
      DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
      Speaker: James Kehler VMD, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      2
      FEB 08, 2017 | 10:30 AM
      Obtaining non-invasive readouts and early safety signals from rodent models
      Obtaining non-invasive readouts and early safety signals from...
      DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe utility of animal models in drug development is limited, in part, by the measures available to researchers for monitoring animals. I...
      Speaker: Laura Schaevitz, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      3
      DEC 01, 2016 | 8:00 AM
      In Vivo Imaging Toolkit: Advancing Preclinical and Translational Science in Molecular and Orthopedic Research at UCLA
      In Vivo Imaging Toolkit: Advancing Preclinical and Translational...
      DATE: December 1, 2016TIME:  8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
      Speaker: Nick Bernthal, MD , Jason Lee, Ph.D
      Sponsored By: Revvity
      3
      NOV 15, 2016 | 9:00 AM
      Antigen-specific, poly-functional CD4+ T cells are required for vaccine-mediated protection in tularemia
      Antigen-specific, poly-functional CD4+ T cells are required for...
      DATE: November 15, 2016 TIME: 9:00 AM PT, 12:00 PM ET The virulent intracellular pathogen Francisella tularensis subsp. tularensis (Ftt) causes an acute, lethal diseas...
      Speaker: Lydia Roberts, PhD
      Sponsored By: Miltenyi Biotec, Miltenyi Biotec
      3
      NOV 02, 2016 | 10:30 AM
      Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
      Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
      Vitamin D3 supplementation can effectively remedy the current epidemic of vitamin D deficiency, especially within the African-American population and the elderly of any ethnicity. Racial disp...
      Speaker: Sebastiano Gattoni-Celli, MD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
      2
    OCT 11, 2017 | 6:00 AM
    Cancer Chemotherapy and the tools needed to Advance Treatment in a Diverse Racial Population
    Cancer Chemotherapy and the tools needed to Advance Treatment...
    Colorectal  cancer  (CRC)  is  the  third  most  commonly  diagnosed  cancer  and  is  the  third leading  cause of  ...
    Speaker: Jennie Williams, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2017
    1
    SEP 28, 2017 | 9:00 AM
    Fine tuning of myosin activity shapes actomyosin network organization and tissue contractility of the C. elegans spermatheca
    Fine tuning of myosin activity shapes actomyosin network organization...
    Contractile non-muscle cells, including smooth muscle and myoepithelial cells, provide the mechanical forces required for tissue homeostasis in numerous organ systems. For example, smooth mus...
    Speaker: Alison Wirshing, PhD
    Presented at: Cell Biology Virtual Event Series 2017
    1
    SEP 13, 2017 | 9:00 AM
    Insights into virus replication: the role of co-opted host proteins and lipids
    Insights into virus replication: the role of co-opted host proteins...
    Virus – host interactions are currently among the most intensively studied research areas due to the promising new antiviral approaches emerging from these studies. Indeed, RNA viruses,...
    Speaker: Peter L. Nagy, MD., PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    3
    SEP 13, 2017 | 6:00 AM
    Next-generation probiotics targeting C. difficile infection
    Next-generation probiotics targeting C. difficile infection
    Adjunct probiotic therapy has the potential to decrease Clostridium difficile disease incidence and severity. After screening several potential probiotic bacteria for intrinsic resistance to...
    Speaker: Jennifer Spinler, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    1
    SEP 06, 2017 | 9:00 AM
    WEBINAR: Manufacturing and characterization of therapeutic exosomes for clinical studies
    WEBINAR: Manufacturing and characterization of therapeutic exosomes...
    DATE: September 6, 2017TIME: 9:00AM PST, 12:00PM ET The era of using extracellular vesicles (EVs) and exosomes for regenerative medicine applications in the clinic is here. We...
    Speaker: Travis Antes, PhD
    Sponsored By: Miltenyi Biotec
    9
     
     
  • JUL 01, 2017 | 12:00 AM
    Physiological Oxygen: Historical and Molecular Perspective for Stem Cell Culture
    Physiological Oxygen: Historical and Molecular Perspective for...
    For many decades, cell lines have been cultured in standard CO2 incubators at “normal” atmospheric oxygen concentrations of about 21%. But oxygen concentrations in the human or an...
    Speaker: Mary Kay Bates, M.S.
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    JUL 01, 2017 | 12:00 AM
    New Tools for improved CRISPR gene-editing in stem cells
    New Tools for improved CRISPR gene-editing in stem cells
    The development of the CRISPR/Cas9 gene-editing platform enables the rapid generation of new genetically modified stem cell models of human diseases, as well as providing new potential therap...
    Speaker: James Kehler VMD, PhD
    Presented at: 5th annual 24 Hours of Stem Cellsâ„¢ virtual event
    2
    JUN 07, 2017 | 9:00 AM
    WEBINAR: Generation of purified human iPSC derived cardiomyocytes using clinically relevant workflow
    WEBINAR: Generation of purified human iPSC derived cardiomyocytes...
    DATE: June 7, 2017TIME: 9:00AM PDT, 12:00PM EDTPluripotent stem cells (PSCs) offer an unlimited source of human cardiovascular cells for research and the development of cardiac regenera...
    Speaker: Todd Herron, BS, PhD
    Sponsored By: Miltenyi Biotec
    5 1
    APR 19, 2017 | 4:00 AM
    WEBINAR: Patient Derived Micro Tumor systems: Future Trends towards improved testing systems
    WEBINAR: Patient Derived Micro Tumor systems: Future Trends towards...
    DATE: April 20th, 2017TIME: 10:00AM SGT, 11:00AM KST, 12:00PM AEST, 2:00PM NZSTWith increasing breadth and depth of genomics studies across a range of cancers, it is now apparent that t...
    Speaker: Giridharan Periyasamy, PhD
    Sponsored By: Revvity
    8
    MAR 15, 2017 | 7:30 AM
    Exercise Targeting Neuroplasticity in Parkinson's disease
    Exercise Targeting Neuroplasticity in Parkinson's disease
    Parkinson’s disease (PD) is characterized by the loss of dopamine and the disruption of brain circuits (basal ganglia and cortex) that are responsible for normal cognitive and motor per...
    Speaker: Giselle Petzinger, MD
    Presented at: Neuroscience Virtual Event Series 2017
    2
     
     
  • FEB 23, 2017 | 12:00 PM
    Recent progress in cellular medicine with an eye to precision medicine
    Recent progress in cellular medicine with an eye to precision...
    Despite vast investment for decades in cancer research and development, cancer is still among the leading causes of death worldwide and its toll is expected to rise by about 70% over the next...
    Speaker: Giacinto Scoles, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    2
    FEB 09, 2017 | 3:00 PM
    Education/Training/CPD from the Chinese perspective
    Education/Training/CPD from the Chinese perspective
    DATE: February 9, 2017TIME: 3:00pm PT, 6:00pm ETThe presentation will very briefly cover the regulatory system for lab animals in China, as well as the regulations and guidelines a...
    Speaker: Wanyong (William) Pang, BVM, MS, PhD, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    2
    FEB 09, 2017 | 10:30 AM
    Combining practical training with virtual training in the continuous development of lab animal vets
    Combining practical training with virtual training in the continuous...
    DATE: February 9, 2017TIME: 10:30am PT, 1:30pm ETDuring the last 50 years the claims for continuous development and training of laboratory animal staff has been progressively devel...
    Speaker: Axel Kornerup Hansen, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    4
    FEB 09, 2017 | 9:00 AM
    Improved decision making in the drug discovery process using an innovative approach to modelling chronic liver disease
    Improved decision making in the drug discovery process using an...
    DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETTraditional models of liver fibrosis in rodents involve many weeks of induction, with frequent injections of a pro-fibrotic agent. The m...
    Speaker: Steve England, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    2
    FEB 09, 2017 | 6:00 AM
    Continuous Professional Development (CPD) in Laboratory Animal Science, a continuous improvement in animal welfare and science
    Continuous Professional Development (CPD) in Laboratory Animal...
    DATE: February 9, 2017TIME: 6:00am PT, 9:00am ETThere is no professional area in which CPD is more necessary than in the field of laboratory animals. The continuous advancement of scien...
    Speaker: Patri Vergara, DVM, PhD, DipECLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    3
     
     
  • FEB 08, 2017 | 3:00 PM
    Management of a research colony of woodchucks (Marmota monax)
    Management of a research colony of woodchucks (Marmota monax)
    DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETThe Eastern woodchuck (Marmota monax) is a large, burrowing rodent with native territories throughout parts of the US and Canada. Woodchu...
    Speaker: Margaret (Peg) Batchelder, DVM, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    2
    FEB 08, 2017 | 3:00 PM
    Alternative Delivery Methods for Post-Operative Analgesia Using Meloxicam in Mice
    Alternative Delivery Methods for Post-Operative Analgesia Using...
    DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETMeloxicam is an analgesic NSAID commonly used in mice. Anecdotal evidence supports the use of alternative delivery methods for analgesics...
    Speaker: Angela Mexas, DVM, PhD, DACVIM, DACLAM , CJ Doane, DVM, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    3 1
    FEB 08, 2017 | 1:30 PM
    Characterization of Niemann Pick Type C mutant mice using automated cage monitoring systems
    Characterization of Niemann Pick Type C mutant mice using automated...
    DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
    Speaker: Sangeetha Iyer, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    1
    FEB 08, 2017 | 12:00 PM
    Availability and Management of Genetically Engineered Swine Models for Biomedical Research
    Availability and Management of Genetically Engineered Swine Models...
    DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETLarge animal models have recently become a staple in biomedical research.  The pig’s similarities to humans in terms of genet...
    Speaker: Eric Walters, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    2
    FEB 08, 2017 | 10:30 AM
    Biosecurity, Reproductive and Social Management of Cat Research Colonies
    Biosecurity, Reproductive and Social Management of Cat Research...
    DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
    Speaker: James Kehler VMD, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    2
     
     
  • FEB 08, 2017 | 10:30 AM
    Obtaining non-invasive readouts and early safety signals from rodent models
    Obtaining non-invasive readouts and early safety signals from...
    DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe utility of animal models in drug development is limited, in part, by the measures available to researchers for monitoring animals. I...
    Speaker: Laura Schaevitz, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    3
    DEC 01, 2016 | 8:00 AM
    In Vivo Imaging Toolkit: Advancing Preclinical and Translational Science in Molecular and Orthopedic Research at UCLA
    In Vivo Imaging Toolkit: Advancing Preclinical and Translational...
    DATE: December 1, 2016TIME:  8:00 AM PT, 11:00 AM ETPreclinical imaging enables the measurement and assessment of biological processes in vivo utilizing technologies such as biolum...
    Speaker: Nick Bernthal, MD , Jason Lee, Ph.D
    Sponsored By: Revvity
    3
    NOV 15, 2016 | 9:00 AM
    Antigen-specific, poly-functional CD4+ T cells are required for vaccine-mediated protection in tularemia
    Antigen-specific, poly-functional CD4+ T cells are required for...
    DATE: November 15, 2016 TIME: 9:00 AM PT, 12:00 PM ET The virulent intracellular pathogen Francisella tularensis subsp. tularensis (Ftt) causes an acute, lethal diseas...
    Speaker: Lydia Roberts, PhD
    Sponsored By: Miltenyi Biotec, Miltenyi Biotec
    3
    NOV 02, 2016 | 10:30 AM
    Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
    Vitamin D, Health Disparities in Prostrate Cancer, and...Alzheimer's
    Vitamin D3 supplementation can effectively remedy the current epidemic of vitamin D deficiency, especially within the African-American population and the elderly of any ethnicity. Racial disp...
    Speaker: Sebastiano Gattoni-Celli, MD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2016
    2
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