Biomarkers: a biomarker, or biological marker, generally refers to a measurable indicator of some biological state or condition. The term is also occasionally used to refer to a substance, the presence of which indicates the existence of a living organism. Further, life forms are known to shed unique chemicals, including DNA, into the environment as evidence of their presence in a particular location.
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Princess Margaret Living Biobank (PMLB) is a repository for patient-derived organoid models. PMLB has generated over200 organoid models from lung, pancreas, colon, ovary, esophageal and brea...
The continued evolution of precision medicine from the early successes seen in Oncology to other areas of medicine, in particular, Chronic Disease Management, is dependent on the efficient t...
Cancer is a leading cause of morbidity and mortality in developed countries including the United States. Early detection of various cancers, before they spread and become incurable, has been...
Integrating external and internal ‘omics data is a key element of hypothesis generation, target identification, and biomarker prioritization when it comes to drug discovery. It is neve...
High-throughput sequencing technology such as RNASeq and whole genome sequencing has enabled deep characterization of health and disease states. Biomarker discovery by these means has only h...