Cancer Therapeutics: Cancer is often treated by surgery, chemotherapy, radiation therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy), hormonal therapy, and synthetic lethality. The choice of therapy depends upon the stage of the disease, and the location and grade of the tumor, as well as the patient's general status. Many clinical trial cancer treatments are also under development.
DATE: May 10th, 2016
TIME: 8:00am Pacific time, 11:00am Eastern time
Cancer is a complex, multifactorial disease that not only is a cause of major human suffering throughout history...
9:00 AM PT, 11:00 AM CT, 12:00 PM ET
Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...
A recently discovered communication system used by cells to send messages across the human body promises to revolutionize our understanding of disease and how we treat it. Technologies based...
The Personalized Medicine Initiative (PMI) is a non-profit enterprise based in Vancouver, Canada that is focused on introducing personalized, molecularly-based medicine into the front lines o...
Pathology departments are under significant pressure to meet the demands of a precise medicine environment where general phenotypic attributes are no longer sufficient for accurately defining...
Oncologists and pathologists are increasingly utilizing information on genomic alterations in tumors to help guide patient care and treatment. Personalis, Inc., a genomic sequencing and inter...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
Cell death is involved in diseases such as cancer and neurodegeneration, and also has a natural role in the development of multicellular organisms. Although apoptosis has been well defined, a...
Every day, vast amounts of healthcare data are collected from clinical trials as well as real world medical visits on patient treatment regimens and subsequent clinical outcomes. This big dat...
DATE: February 2nd, 2016
TIME: 9am pacific time, 12pm eastern time
What is the most appropriate technology to empower your research?
Next generation sequencing (NGS) for RN...
Over the past decade, there has been a rapid growth in studies of secreted membrane vesicles, collectively called extracellular vesicles (EVs). (1) The release of EVs has been reported in the...
Next-generation sequencing has emerged as a valuable tool for generating patient-specific genetic information for clinical diagnostics and optimal selection of targeted therapies. The heterog...
DATE: November 4th, 2015
TIME: 11:00am Pacific time, 2:00pm Eastern time
AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...
The 95% failure rate of anticancer therapeutic being approved after positive Phase III trials suggests that existing pre-clinical approaches and tools are inadequate predictors of clinical ou...
While TDM is routinely used in a number of medical fields, it has not gained wide utilization in oncology. There is a growing body of evidence demonstrating that current dosing methods based...
Melanoma, a cancer of pigment-producing cells, accounts for nearly 200,000 new cases of cancer reported each year worldwide. It is the deadliest skin cancer. Alarmingly, in the U.S., the inci...
Biomarkers, with their associated “tsunami” of publications, represent what is arguably one of the largest areas of scientific inquiry in the history of biomedicine. Touted as the...
Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
The Warburg effect or aerobic glycolysis is a well-known cancer metabolism phenomenon and serves as an established test for tumor detection with FDG-PET scanning technology. Cancer cells swit...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
The landscape for treatment options in metastatic castration resistant prostate cancer has changed dramatically since 2010. There have been more therapies approved since 2010 than in the prio...
LEARNING OBJECTIVES:1. Enhanced audience understanding regarding the controversy surrounding prostate cancer screening using the PSA blood test and use of the American Uro...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
DATE: May 10th, 2016
TIME: 8:00am Pacific time, 11:00am Eastern time
Cancer is a complex, multifactorial disease that not only is a cause of major human suffering throughout history...
9:00 AM PT, 11:00 AM CT, 12:00 PM ET
Epigenetics defines the set of distinct and heritable molecular mechanisms able to influence gene expression without altering the primary genetic seque...
A recently discovered communication system used by cells to send messages across the human body promises to revolutionize our understanding of disease and how we treat it. Technologies based...
The Personalized Medicine Initiative (PMI) is a non-profit enterprise based in Vancouver, Canada that is focused on introducing personalized, molecularly-based medicine into the front lines o...
Pathology departments are under significant pressure to meet the demands of a precise medicine environment where general phenotypic attributes are no longer sufficient for accurately defining...
Oncologists and pathologists are increasingly utilizing information on genomic alterations in tumors to help guide patient care and treatment. Personalis, Inc., a genomic sequencing and inter...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
Cell death is involved in diseases such as cancer and neurodegeneration, and also has a natural role in the development of multicellular organisms. Although apoptosis has been well defined, a...
Every day, vast amounts of healthcare data are collected from clinical trials as well as real world medical visits on patient treatment regimens and subsequent clinical outcomes. This big dat...
DATE: February 2nd, 2016
TIME: 9am pacific time, 12pm eastern time
What is the most appropriate technology to empower your research?
Next generation sequencing (NGS) for RN...
Over the past decade, there has been a rapid growth in studies of secreted membrane vesicles, collectively called extracellular vesicles (EVs). (1) The release of EVs has been reported in the...
Next-generation sequencing has emerged as a valuable tool for generating patient-specific genetic information for clinical diagnostics and optimal selection of targeted therapies. The heterog...
DATE: November 4th, 2015
TIME: 11:00am Pacific time, 2:00pm Eastern time
AMPK, a highly conserved sensor of cellular energy status, is found in all eukaryotic cells and maintains met...
The 95% failure rate of anticancer therapeutic being approved after positive Phase III trials suggests that existing pre-clinical approaches and tools are inadequate predictors of clinical ou...
While TDM is routinely used in a number of medical fields, it has not gained wide utilization in oncology. There is a growing body of evidence demonstrating that current dosing methods based...
Melanoma, a cancer of pigment-producing cells, accounts for nearly 200,000 new cases of cancer reported each year worldwide. It is the deadliest skin cancer. Alarmingly, in the U.S., the inci...
Biomarkers, with their associated “tsunami” of publications, represent what is arguably one of the largest areas of scientific inquiry in the history of biomedicine. Touted as the...
Hepatocellular carcinoma (HCC) is a significant contributor to cancer-related mortality in the United States and worldwide. Current treatments are largely ineffective: single agent and combin...
The Warburg effect or aerobic glycolysis is a well-known cancer metabolism phenomenon and serves as an established test for tumor detection with FDG-PET scanning technology. Cancer cells swit...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
The landscape for treatment options in metastatic castration resistant prostate cancer has changed dramatically since 2010. There have been more therapies approved since 2010 than in the prio...
LEARNING OBJECTIVES:1. Enhanced audience understanding regarding the controversy surrounding prostate cancer screening using the PSA blood test and use of the American Uro...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
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