Follow
Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
-
AUG 07, 2015Neuroscience
We have all experienced what it feels like to be "hangry" - hungry and angry at the same time. A new study on this pheno ...Written By: Kara MarkerAUG 06, 2015Cancer
How do tumors grow, and how can they be stopped? A collaborative study between Sanford Burnham Prebys Medical Discovery ...Written By: Ilene SchneiderAUG 05, 2015Genetics & Genomics
While skeletal muscle is abundant in the human body, it been difficult for researchers to derive muscle cells from precu ...Written By: Ilene SchneiderAUG 04, 2015Genetics & Genomics
A gene on a chromosome linked with Down syndrome also has implications for developing childhood leukemia, according to r ...Written By: Ilene SchneiderAUG 03, 2015Cancer
Why does melanoma, which accounts for 2 percent of skin cancer cases, cause almost all skin cancer deaths? Why have mela ...Written By: Ilene SchneiderAUG 01, 2015Earth & The Environment
A San Francisco-based sightseeing cruise line called The Red and White Fleet has taken on a new project. Certainly, if i ...Written By: Andrew J. DunlopJUL 30, 2015Cancer
The most common type of lung cancer, which is also the most common cause of cancer deaths, is resistant to a cytokine ca ...Written By: Ilene Schneider
