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    Computational Mechanics

    Computational Mechanics: is the use of computational methods to study phenomena governed by the principles of mechanics.

    Webinars

    • SEP 23, 2020 | 7:00 AM
      Meet the Expert
      Meet the Expert
      Come join us for a live chat with Bernd Bodenmiller. When you enter the meeting room you can raise your hand to be unmuted by our moderator to ask your questions or just introduce yourself a...
      Speaker: Bernd Bodenmiller, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      1
      SEP 23, 2020 | 6:30 AM
      Mass Cytometry in Translational Research: Session I
      Mass Cytometry in Translational Research: Session I
      Single-cell mass cytometry identifies mechanisms of resistance to immunotherapy in AML 6:30–7:00 am PDT Presented By: Shelley Herbrich, PhD Understanding CD19 negative relapse followin...
      Speaker: Shelley Herbrich, PhD , Kara L. Davis, DO , Bernd Bodenmiller, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      2
      SEP 17, 2020 | 3:30 PM
      Discovery of a druggable pocket in SARS-CoV-2 Spike: New avenue to defeat COVID-19?
      Discovery of a druggable pocket in SARS-CoV-2 Spike: New avenue...
      COVID-19 has developed into a crisis of global proportions. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Key to SARS-CoV-2 therapeutic development is u...
      Speaker: Imre Berger
      Presented at: Coronavirus Series
      Sponsored By: GenScript
      2
      SEP 08, 2020 | 11:00 PM
      Applications of Machine Learning to Predict Clinical Provenance of Haemophilus influenzae
      Applications of Machine Learning to Predict Clinical Provenance...
      Background: Haemophilus influenzae is the causative agent of multiple human disease conditions among multiple sites in the human body. Underlying genetic mechanisms are elusive, particularly...
      Speaker: Joshua Earl, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 01, 2020 | 8:00 AM
      Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
      Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
      DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
      Speaker: Justin Balko
      Sponsored By: Thermo Fisher Scientific
      20 1
      AUG 06, 2020 | 10:00 AM
      Part V: Mechanisms for perceptual organization in the rodent visual cortex
      Part V: Mechanisms for perceptual organization in the rodent visual...
      The rodent visual system has attracted great interest in recent years, owing to its experimental tractability, but the fundamental mechanisms used by the mouse to represent the visual world...
      Speaker: Francisco Luongo, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      Causes and consequences of rapid cancer cell adaptation to therapeutic drugs
      Causes and consequences of rapid cancer cell adaptation to therapeutic...
      Despite the increasing number of effective anti-cancer therapies, successful treatment is limited by the development of drug resistance. While the contribution of genetic factors to drug res...
      Speaker: Sabrina Spencer, PhD
      Presented at: 2020 Beckman Symposium
      1
      AUG 06, 2020 | 12:00 AM
      Neuromechanics of Locomotor Transitions on Energy Landscapes of Complex Terrain
      Neuromechanics of Locomotor Transitions on Energy Landscapes of...
      Effective locomotion in nature happens by transitioning between multiple modes (e.g., walk, run, climb, slither). Despite this, far more mechanistic understanding of terrestrial locomotion h...
      Speaker: Chen Li, PhD
      Presented at: 2020 Beckman Symposium
      1
      JUL 09, 2020 | 11:00 AM
      Learning to aggress: from complex social behavior to whole brain light sheet microscopy
      Learning to aggress: from complex social behavior to whole brain...
      DATE: July 9, 2020 TIME: 11:00am PT Maladaptive aggression is an immutable force that contributes to the suffering and death of millions of people around the world annually, as well as prese...
      Speaker: Sam Golden, Ph.D
      Sponsored By: Miltenyi Biotec
      10
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
      MAY 14, 2020 | 10:00 AM
      Massively Parallel Genome Engineering followed by pooled growth selections for rapid target discovery in microbes
      Massively Parallel Genome Engineering followed by pooled growth...
      DATE: May 14, 2020 TIME: 10:00am PT, 1:00pm ET Massively parallel genome engineering enables rapid and simultaneous evaluation of genotype-phenotype relationships at a genomic scale....
      Speaker: Stephen Federowicz, Ph.D.
      Sponsored By: Inscripta
      7
      MAY 14, 2020 | 12:00 AM
      Tissue Chips: Building Confidence Through Independent Experimental Testing
      Tissue Chips: Building Confidence Through Independent Experimental...
      Experimental models that promise to replace animal tests that are currently required for drugs and chemicals are rapidly proliferating. This includes a number of novel solutions offered by b...
      Speaker: Ivan Rusyn, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2020
      0
      MAY 13, 2020 | 9:00 AM
      Get Closer to the Truth: STELLARIS - Confocal Re-Imagined
      Get Closer to the Truth: STELLARIS - Confocal Re-Imagined
      DATE: May 13, 2020 TIME: 9:00am PT, 12:00pm ET STELLARIS. Confocal re-imagined. In microscopy, our mission is to empower you to drive progress in science. To get you closer to the truth, we...
      Speaker: Petra Haas, Ph.D. , Julia Roberti, Ph.D.
      Sponsored By: Leica Microsystems
      14
      MAY 12, 2020 | 9:00 AM
      Analytical Quality Control for the Pharmaceutical Industry
      Analytical Quality Control for the Pharmaceutical Industry
      NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
      Speaker: Joy McElroy
      Sponsored By: Sartorius
      29 9
      MAY 12, 2020 | 8:00 AM
      Deep phenotyping of Tregs in health and disease - lessons from Bone Marrow Failure Syndromes
      Deep phenotyping of Tregs in health and disease - lessons from...
      DATE: May 12, 2020 TIME: 8:00am PT Idiopathic aplastic anemia (AA) has two key characteristics: an autoimmune response against hematopoietic stem/progenitor cells and regulatory T cells (Tre...
      Speaker: Dr. Shahram Kordasti
      Sponsored By: Beckman Coulter Life Sciences
      13 3
      APR 29, 2020 | 9:00 AM
      The THUNDER Imager EM Cryo CLEM - How to identify and retrieve your cellular targets for Cryo Electron Microscopy
      The THUNDER Imager EM Cryo CLEM - How to identify and retrieve...
      DATE: April 29, 2020 TIME: 9:00am PT, 12:00pm ET Recent revolutionary developments in the field of cryo electron microscopy (EM) revealed cellular mechanisms in subnanometer resolution. Unfo...
      Speaker: Jan De Bock, PhD
      Sponsored By: Leica Microsystems
      10
      APR 24, 2020 | 8:00 AM
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
      Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
      DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
      Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
      Sponsored By: Bionano
      11
      APR 16, 2020 | 9:00 AM
      Visualize more biomarkers and extract more insights: Moving from single marker IHC to multiplex IF
      Visualize more biomarkers and extract more insights: Moving from...
      DATE: April 16, 2020 TIME: 9:00am PT, 12:00pm ET There is an increasing need to evaluate and understand unique phenotypes and mechanisms of action within the tumor microenvironment. Existing...
      Speaker: Scott Lawrence (M.S., HT(ASCP)) [C] , Katir Patel, PhD
      Sponsored By: Ultivue
      5
      APR 02, 2020 | 8:00 AM
      Bionano Genome Imaging unravels complex structural rearrangements induced by replication stress in liver cancer
      Bionano Genome Imaging unravels complex structural rearrangements...
      DATE: April 2, 2020 TIME: 8:00am PT, 11:00am ET Cyclins A2 and E1 regulate the cell cycle by promoting S phase entry and progression. We recently identified a hepatocellular carcinoma (HCC)...
      Speaker: Eric Letouzé, PhD
      Sponsored By: Bionano
      14
      MAR 11, 2020 | 3:00 PM
      PANEL: A Team Multi-Disciplinary Approach to Understanding the Neural Circuit Dynamics Underlying Working Memory and Decision-Making
      PANEL: A Team Multi-Disciplinary Approach to Understanding the...
      Working memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...
      Speaker: Carlos Brody, PhD , Ben Engelhard, PhD , Stephen Keeley, PhD , Marlies Oostland, PhD , Lucas Pinto, MD, PhD , Adrian Wanner, PhD , Ilana Witten, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 3:00 PM
      PANEL: Anatomical Characterization of Neuron Cell Types in the Mouse Brain
      PANEL: Anatomical Characterization of Neuron Cell Types in the...
      Identifying the diversity of neuronal cell types of the nervous system is one of the main objectives of the BRAIN Initiative, with the vision that distinct neuronal identities will allow for...
      Speaker: Giorgio Ascoli, PhD , Hong-Wei Dong, MD, PhD , Byungkook Lim, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 1:30 PM
      PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary Consortium Utilizing Human Single-Neuron Recordings
      PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary...
      Episodic memories are essential for human cognition, but the underlying neural mechanisms remain poorly understood. We utilize the opportunity to record in-vivo from human single neurons sim...
      Speaker: Adam Mamelak, MD , Ueli Rutishauser, PhD , Gabriel Kreiman, PhD , Jie Zheng, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 1:30 PM
      PANEL: Dissecting the circuit logics in the amygdala underlying emotional learning
      PANEL: Dissecting the circuit logics in the amygdala underlying...
      Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
      Speaker: Bo Li , Tianyi Mao , Haining Zhong
      Presented at: Neuroscience Virtual Event Series 2020
      1
      MAR 11, 2020 | 12:00 PM
      PANEL: Cracking a Neural Circuit's Function Through High-Resolution Physiology, Connectomics, and Computational Modeling
      PANEL: Cracking a Neural Circuit's Function Through High-Resolution...
      Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
      Speaker: Emre Aksay, PhD , Mark Goldman, PhD , Sebastian Seung, PhD , Ashwin Vishwanathan, PhD
      Presented at: Neuroscience Virtual Event Series 2020
      1 1
    SEP 23, 2020 | 7:00 AM
    Meet the Expert
    Meet the Expert
    Come join us for a live chat with Bernd Bodenmiller. When you enter the meeting room you can raise your hand to be unmuted by our moderator to ask your questions or just introduce yourself a...
    Speaker: Bernd Bodenmiller, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    1
    SEP 23, 2020 | 6:30 AM
    Mass Cytometry in Translational Research: Session I
    Mass Cytometry in Translational Research: Session I
    Single-cell mass cytometry identifies mechanisms of resistance to immunotherapy in AML 6:30–7:00 am PDT Presented By: Shelley Herbrich, PhD Understanding CD19 negative relapse followin...
    Speaker: Shelley Herbrich, PhD , Kara L. Davis, DO , Bernd Bodenmiller, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    2
    SEP 17, 2020 | 3:30 PM
    Discovery of a druggable pocket in SARS-CoV-2 Spike: New avenue to defeat COVID-19?
    Discovery of a druggable pocket in SARS-CoV-2 Spike: New avenue...
    COVID-19 has developed into a crisis of global proportions. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Key to SARS-CoV-2 therapeutic development is u...
    Speaker: Imre Berger
    Presented at: Coronavirus Series
    Sponsored By: GenScript
    2
    SEP 08, 2020 | 11:00 PM
    Applications of Machine Learning to Predict Clinical Provenance of Haemophilus influenzae
    Applications of Machine Learning to Predict Clinical Provenance...
    Background: Haemophilus influenzae is the causative agent of multiple human disease conditions among multiple sites in the human body. Underlying genetic mechanisms are elusive, particularly...
    Speaker: Joshua Earl, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 01, 2020 | 8:00 AM
    Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
    Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
    DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
    Speaker: Justin Balko
    Sponsored By: Thermo Fisher Scientific
    20 1
     
     
  • AUG 06, 2020 | 10:00 AM
    Part V: Mechanisms for perceptual organization in the rodent visual cortex
    Part V: Mechanisms for perceptual organization in the rodent visual...
    The rodent visual system has attracted great interest in recent years, owing to its experimental tractability, but the fundamental mechanisms used by the mouse to represent the visual world...
    Speaker: Francisco Luongo, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 12:00 AM
    Causes and consequences of rapid cancer cell adaptation to therapeutic drugs
    Causes and consequences of rapid cancer cell adaptation to therapeutic...
    Despite the increasing number of effective anti-cancer therapies, successful treatment is limited by the development of drug resistance. While the contribution of genetic factors to drug res...
    Speaker: Sabrina Spencer, PhD
    Presented at: 2020 Beckman Symposium
    1
    AUG 06, 2020 | 12:00 AM
    Neuromechanics of Locomotor Transitions on Energy Landscapes of Complex Terrain
    Neuromechanics of Locomotor Transitions on Energy Landscapes of...
    Effective locomotion in nature happens by transitioning between multiple modes (e.g., walk, run, climb, slither). Despite this, far more mechanistic understanding of terrestrial locomotion h...
    Speaker: Chen Li, PhD
    Presented at: 2020 Beckman Symposium
    1
    JUL 09, 2020 | 11:00 AM
    Learning to aggress: from complex social behavior to whole brain light sheet microscopy
    Learning to aggress: from complex social behavior to whole brain...
    DATE: July 9, 2020 TIME: 11:00am PT Maladaptive aggression is an immutable force that contributes to the suffering and death of millions of people around the world annually, as well as prese...
    Speaker: Sam Golden, Ph.D
    Sponsored By: Miltenyi Biotec
    10
    JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
     
     
  • MAY 14, 2020 | 10:00 AM
    Massively Parallel Genome Engineering followed by pooled growth selections for rapid target discovery in microbes
    Massively Parallel Genome Engineering followed by pooled growth...
    DATE: May 14, 2020 TIME: 10:00am PT, 1:00pm ET Massively parallel genome engineering enables rapid and simultaneous evaluation of genotype-phenotype relationships at a genomic scale....
    Speaker: Stephen Federowicz, Ph.D.
    Sponsored By: Inscripta
    7
    MAY 14, 2020 | 12:00 AM
    Tissue Chips: Building Confidence Through Independent Experimental Testing
    Tissue Chips: Building Confidence Through Independent Experimental...
    Experimental models that promise to replace animal tests that are currently required for drugs and chemicals are rapidly proliferating. This includes a number of novel solutions offered by b...
    Speaker: Ivan Rusyn, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2020
    0
    MAY 13, 2020 | 9:00 AM
    Get Closer to the Truth: STELLARIS - Confocal Re-Imagined
    Get Closer to the Truth: STELLARIS - Confocal Re-Imagined
    DATE: May 13, 2020 TIME: 9:00am PT, 12:00pm ET STELLARIS. Confocal re-imagined. In microscopy, our mission is to empower you to drive progress in science. To get you closer to the truth, we...
    Speaker: Petra Haas, Ph.D. , Julia Roberti, Ph.D.
    Sponsored By: Leica Microsystems
    14
    MAY 12, 2020 | 9:00 AM
    Analytical Quality Control for the Pharmaceutical Industry
    Analytical Quality Control for the Pharmaceutical Industry
    NEW DATE: Date: May 12, 2020 Time: 9:00am PDT, 12:00pm EDT...
    Speaker: Joy McElroy
    Sponsored By: Sartorius
    29 9
    MAY 12, 2020 | 8:00 AM
    Deep phenotyping of Tregs in health and disease - lessons from Bone Marrow Failure Syndromes
    Deep phenotyping of Tregs in health and disease - lessons from...
    DATE: May 12, 2020 TIME: 8:00am PT Idiopathic aplastic anemia (AA) has two key characteristics: an autoimmune response against hematopoietic stem/progenitor cells and regulatory T cells (Tre...
    Speaker: Dr. Shahram Kordasti
    Sponsored By: Beckman Coulter Life Sciences
    13 3
     
     
  • APR 29, 2020 | 9:00 AM
    The THUNDER Imager EM Cryo CLEM - How to identify and retrieve your cellular targets for Cryo Electron Microscopy
    The THUNDER Imager EM Cryo CLEM - How to identify and retrieve...
    DATE: April 29, 2020 TIME: 9:00am PT, 12:00pm ET Recent revolutionary developments in the field of cryo electron microscopy (EM) revealed cellular mechanisms in subnanometer resolution. Unfo...
    Speaker: Jan De Bock, PhD
    Sponsored By: Leica Microsystems
    10
    APR 24, 2020 | 8:00 AM
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide Structural Variant Analysis
    Isolating Ultra-high Molecular Weight (UHMW) DNA for Genome-wide...
    DATE: April 24, 2020 TIME: 8:00am PT, 11:00am ET, 5:00pm CET...
    Speaker: Ben Clifford, PhD , Sven Bocklandt, PhD
    Sponsored By: Bionano
    11
    APR 16, 2020 | 9:00 AM
    Visualize more biomarkers and extract more insights: Moving from single marker IHC to multiplex IF
    Visualize more biomarkers and extract more insights: Moving from...
    DATE: April 16, 2020 TIME: 9:00am PT, 12:00pm ET There is an increasing need to evaluate and understand unique phenotypes and mechanisms of action within the tumor microenvironment. Existing...
    Speaker: Scott Lawrence (M.S., HT(ASCP)) [C] , Katir Patel, PhD
    Sponsored By: Ultivue
    5
    APR 02, 2020 | 8:00 AM
    Bionano Genome Imaging unravels complex structural rearrangements induced by replication stress in liver cancer
    Bionano Genome Imaging unravels complex structural rearrangements...
    DATE: April 2, 2020 TIME: 8:00am PT, 11:00am ET Cyclins A2 and E1 regulate the cell cycle by promoting S phase entry and progression. We recently identified a hepatocellular carcinoma (HCC)...
    Speaker: Eric Letouzé, PhD
    Sponsored By: Bionano
    14
    MAR 11, 2020 | 3:00 PM
    PANEL: A Team Multi-Disciplinary Approach to Understanding the Neural Circuit Dynamics Underlying Working Memory and Decision-Making
    PANEL: A Team Multi-Disciplinary Approach to Understanding the...
    Working memory (the ability to hold some information in mind for a few seconds, and to manipulate that information) and decision-making (committing to one out of multiple possible choices) a...
    Speaker: Carlos Brody, PhD , Ben Engelhard, PhD , Stephen Keeley, PhD , Marlies Oostland, PhD , Lucas Pinto, MD, PhD , Adrian Wanner, PhD , Ilana Witten, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
     
     
  • MAR 11, 2020 | 3:00 PM
    PANEL: Anatomical Characterization of Neuron Cell Types in the Mouse Brain
    PANEL: Anatomical Characterization of Neuron Cell Types in the...
    Identifying the diversity of neuronal cell types of the nervous system is one of the main objectives of the BRAIN Initiative, with the vision that distinct neuronal identities will allow for...
    Speaker: Giorgio Ascoli, PhD , Hong-Wei Dong, MD, PhD , Byungkook Lim, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 1:30 PM
    PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary Consortium Utilizing Human Single-Neuron Recordings
    PANEL: The Neuronal Mechanisms of Human Episodic Memory: a Multidisciplinary...
    Episodic memories are essential for human cognition, but the underlying neural mechanisms remain poorly understood. We utilize the opportunity to record in-vivo from human single neurons sim...
    Speaker: Adam Mamelak, MD , Ueli Rutishauser, PhD , Gabriel Kreiman, PhD , Jie Zheng, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 1:30 PM
    PANEL: Dissecting the circuit logics in the amygdala underlying emotional learning
    PANEL: Dissecting the circuit logics in the amygdala underlying...
    Learning is often an emotional process. Emotional stimuli with different valences, such as threat and reward, can transform an otherwise neutral sensory input into one that can trigger disti...
    Speaker: Bo Li , Tianyi Mao , Haining Zhong
    Presented at: Neuroscience Virtual Event Series 2020
    1
    MAR 11, 2020 | 12:00 PM
    PANEL: Cracking a Neural Circuit's Function Through High-Resolution Physiology, Connectomics, and Computational Modeling
    PANEL: Cracking a Neural Circuit's Function Through High-Resolution...
    Mechanistic understanding of neural systems is daunting to achieve in large part due to the heterogeneity of the neuronal elements in both form and function and the complexity of the circuit...
    Speaker: Emre Aksay, PhD , Mark Goldman, PhD , Sebastian Seung, PhD , Ashwin Vishwanathan, PhD
    Presented at: Neuroscience Virtual Event Series 2020
    1 1
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