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    CRISPR

    CRISPR is an abbreviation of Clustered Regularly Interspaced Short Palindromic Repeats. The name was minted at a time when the origin and use of the interspacing subsequences were not known. At that time the CRISPRs were described as segments of prokaryotic DNA containing short, repetitive base sequences. In a palindromic repeat, the sequence of nucleotides is the same in both directions. Each repetition is followed by short segments of spacer DNA from previous exposures to foreign DNA (e.g., a virus or plasmid). Small clusters of cas (CRISPR-associated) genes are located next to CRISPR sequences.

    Trending News

    • AUG 23, 2019
      Genetics & Genomics
      Altering Dozens or Hundreds of Genes at Once
      Altering Dozens or Hundreds of Genes at Once
      Since it was developed, the CRISPR gene editing system has been refined and advanced.
      Written By: Carmen Leitch
      3
      AUG 18, 2019
      Genetics & Genomics
      Modified CRISPR Can Manipulate Gene Activity in Neurons
      Modified CRISPR Can Manipulate Gene Activity in Neurons
      There are challenges to working with nerve cells in the lab, which can create research bottlenecks in the study of neuro ...
      Written By: Carmen Leitch
      1
      AUG 06, 2019
      Cell & Molecular Biology
      Relieving a Mechanism That Could Underlie as Many as 20 Rare Disorders
      Relieving a Mechanism That Could Underlie as Many as 20 Rare Disorders
      Toxic proteinopathies are a group of inherited diseases that are caused when improperly folded proteins accumulate in th ...
      Written By: Carmen Leitch
      2
      JUL 31, 2019
      Cell & Molecular Biology
      Insight Into a Common Mechanism Underlying Some Neurodevelopmental Disorders
      Insight Into a Common Mechanism Underlying Some Neurodevelopmental Disorders
      Mutations impacting a protein complex called SWI/SNF can cause a variety of problems. Now researchers know more about wh ...
      Written By: Carmen Leitch
      2
      JUL 30, 2019
      Genetics & Genomics
      In a First, Sickle Cell Patient Receives CRISPR Gene Therapy
      In a First, Sickle Cell Patient Receives CRISPR Gene Therapy
      Many human diseases can be traced back to genetic mutations, and researchers are beginning to find ways to correct those ...
      Written By: Carmen Leitch
      1
      JUL 28, 2019
      Genetics & Genomics
      New Drug Targets for Lung Cancer Identified
      New Drug Targets for Lung Cancer Identified
      Researchers at the Salk Institute have now learned why certain genetic mutations lead to cancer growth.
      Written By: Carmen Leitch
      1
      JUL 26, 2019
      Cell & Molecular Biology
      LOCKR: A New Way to Control Cellular Function Synthetically
      LOCKR: A New Way to Control Cellular Function Synthetically
      A totally synthetic protein has been created to act like a switch that can change gene expression in a cell.
      Written By: Carmen Leitch
      2
      JUL 24, 2019
      Cell & Molecular Biology
      Could we be allergic to CRISPR?
      Could we be allergic to CRISPR?
      A new study published in Nature reveals an immunity to the CRISPR-Cas9 proteins in humans
      Written By: Carly Boyd
      2
      JUL 23, 2019
      Cell & Molecular Biology
      Exosomes are Involved in Brain Development
      Exosomes are Involved in Brain Development
      Researchers have learned more about the role of exosomes in neurodevelopment.
      Written By: Carmen Leitch
      1
      JUL 22, 2019
      Genetics & Genomics
      New Diabetes Gene Revealed by Large Study of African Populations
      New Diabetes Gene Revealed by Large Study of African Populations
      While we all carry more or less the same genes, tiny differences in the sequences of those genes can have major ramifica ...
      Written By: Carmen Leitch
      2
      JUL 16, 2019
      Genetics & Genomics
      Lipid Nanoparticles Improve the Delivery of CRISPR/Cas9 Into Cells
      Lipid Nanoparticles Improve the Delivery of CRISPR/Cas9 Into Cells
      The CRISPR/Cas9 gene editing tool has revolutionized biomedical research and has tremendous potential for use in the cli ...
      Written By: Carmen Leitch
      1
      JUL 08, 2019
      Genetics & Genomics
      A CRISPR System can Edit Only a Defective Copy of a Gene
      A CRISPR System can Edit Only a Defective Copy of a Gene
      With a more precise version of CRISPR/Cas9, researchers altered a single, mutated copy of a gene, leaving the correct on ...
      Written By: Carmen Leitch
      1
      JUL 04, 2019
      Genetics & Genomics
      Combination Therapy Eliminates HIV From Rodent Model
      Combination Therapy Eliminates HIV From Rodent Model
      In 2017, 1.8 million new cases of HIV infection were diagnosed around the world, and around 37 million people live with ...
      Written By: Carmen Leitch
      1
      JUN 24, 2019
      Cell & Molecular Biology
      Using CRISPR to Improve Agriculture
      Using CRISPR to Improve Agriculture
      The CRISPR tool has been modified and refined since it was invented, and now scientists have created another way to use ...
      Written By: Carmen Leitch
      1
      JUN 10, 2019
      Genetics & Genomics
      CRISPR 2.0: Using Transposons to Improve and Expand CRISPR Application
      CRISPR 2.0: Using Transposons to Improve and Expand CRISPR Application
      Source: Science CRISPR-cas9, commonly referred to simply as CRISPR, is a bacterial immune system that was first used as ...
      Written By: Amanda Mikyska
      4
      JUN 07, 2019
      Health & Medicine
      In Vivo Tissue Stem Cell and Progenitor Cell Genome Modification
      In Vivo Tissue Stem Cell and Progenitor Cell Genome Modification
      A stem cell, by definition, must be able to self-replicate to make more stem cells and to differentiate into a matu ...
      Written By: Dena Aruta
      1
      JUN 03, 2019
      Genetics & Genomics
      CRISPR Babies May Face Shortened Lifespan
      CRISPR Babies May Face Shortened Lifespan
      Genetic mutations can lead to disease, and scientists have been searching for ways to effectively and safely repair such ...
      Written By: Carmen Leitch
      1
      JUN 01, 2019
      Genetics & Genomics
      How Cas13 Works in Bacteria
      How Cas13 Works in Bacteria
      Cas13 makes a great diagnostic tool, and now researchers know why it naturally makes so many cuts in RNA.
      Written By: Carmen Leitch
      1
      MAY 22, 2019
      Genetics & Genomics
      Insights Into the Cause of Mitral Valve Prolapse
      Insights Into the Cause of Mitral Valve Prolapse
      Most cells in the body have a small appendage called a primary cilium, which is increasingly being recognized for its im ...
      Written By: Carmen Leitch
      1
      MAY 12, 2019
      Genetics & Genomics
      How Long Can We Live For?
      How Long Can We Live For?
      The average human lifespan before the 1900’s was between 30 and 40 years old. It is now between 70 and 85 years ol ...
      Written By: Annie Lennon
      2
      MAY 01, 2019
      Cell & Molecular Biology
      Antidote to Deadly Box Jellyfish Venom Developed Using CRISPR
      Antidote to Deadly Box Jellyfish Venom Developed Using CRISPR
      The Australian box jellyfish can be deadly. They are the most venomous marine creature, and one can kill up to 60 people ...
      Written By: Carmen Leitch
      1
      APR 25, 2019
      Genetics & Genomics
      Using Wild Plant Traits to Reduce Pesticide Use
      Using Wild Plant Traits to Reduce Pesticide Use
      Pesticides are a part of agriculture, and while they are important to crop production, some can be detrimental to human ...
      Written By: Carmen Leitch
      1
      APR 24, 2019
      Genetics & Genomics
      Using CRISPR to Create New Model Organisms
      Using CRISPR to Create New Model Organisms
      There are some animal that could offer incredible insight into health and disease, but we've lacked the tools and the kn ...
      Written By: Carmen Leitch
      1
      APR 20, 2019
      Genetics & Genomics
      New Technique Identifies Off-target Effects of CRISPR
      New Technique Identifies Off-target Effects of CRISPR
      CRISPR, holds a lot of promise as a potential therapeutic. But there are hurdles, like the potential for unintended edit ...
      Written By: Carmen Leitch
      2
    AUG 23, 2019
    Genetics & Genomics
    Altering Dozens or Hundreds of Genes at Once
    Altering Dozens or Hundreds of Genes at Once
    Since it was developed, the CRISPR gene editing system has been refined and advanced.
    Written By: Carmen Leitch
    3
    AUG 18, 2019
    Genetics & Genomics
    Modified CRISPR Can Manipulate Gene Activity in Neurons
    Modified CRISPR Can Manipulate Gene Activity in Neurons
    There are challenges to working with nerve cells in the lab, which can create research bottlenecks in the study of neuro ...
    Written By: Carmen Leitch
    1
    AUG 06, 2019
    Cell & Molecular Biology
    Relieving a Mechanism That Could Underlie as Many as 20 Rare Disorders
    Relieving a Mechanism That Could Underlie as Many as 20 Rare Disorders
    Toxic proteinopathies are a group of inherited diseases that are caused when improperly folded proteins accumulate in th ...
    Written By: Carmen Leitch
    2
    JUL 31, 2019
    Cell & Molecular Biology
    Insight Into a Common Mechanism Underlying Some Neurodevelopmental Disorders
    Insight Into a Common Mechanism Underlying Some Neurodevelopmental Disorders
    Mutations impacting a protein complex called SWI/SNF can cause a variety of problems. Now researchers know more about wh ...
    Written By: Carmen Leitch
    2
    JUL 30, 2019
    Genetics & Genomics
    In a First, Sickle Cell Patient Receives CRISPR Gene Therapy
    In a First, Sickle Cell Patient Receives CRISPR Gene Therapy
    Many human diseases can be traced back to genetic mutations, and researchers are beginning to find ways to correct those ...
    Written By: Carmen Leitch
    1
     
     
  • JUL 28, 2019
    Genetics & Genomics
    New Drug Targets for Lung Cancer Identified
    New Drug Targets for Lung Cancer Identified
    Researchers at the Salk Institute have now learned why certain genetic mutations lead to cancer growth.
    Written By: Carmen Leitch
    1
    JUL 26, 2019
    Cell & Molecular Biology
    LOCKR: A New Way to Control Cellular Function Synthetically
    LOCKR: A New Way to Control Cellular Function Synthetically
    A totally synthetic protein has been created to act like a switch that can change gene expression in a cell.
    Written By: Carmen Leitch
    2
    JUL 24, 2019
    Cell & Molecular Biology
    Could we be allergic to CRISPR?
    Could we be allergic to CRISPR?
    A new study published in Nature reveals an immunity to the CRISPR-Cas9 proteins in humans
    Written By: Carly Boyd
    2
    JUL 23, 2019
    Cell & Molecular Biology
    Exosomes are Involved in Brain Development
    Exosomes are Involved in Brain Development
    Researchers have learned more about the role of exosomes in neurodevelopment.
    Written By: Carmen Leitch
    1
    JUL 22, 2019
    Genetics & Genomics
    New Diabetes Gene Revealed by Large Study of African Populations
    New Diabetes Gene Revealed by Large Study of African Populations
    While we all carry more or less the same genes, tiny differences in the sequences of those genes can have major ramifica ...
    Written By: Carmen Leitch
    2
     
     
  • JUL 16, 2019
    Genetics & Genomics
    Lipid Nanoparticles Improve the Delivery of CRISPR/Cas9 Into Cells
    Lipid Nanoparticles Improve the Delivery of CRISPR/Cas9 Into Cells
    The CRISPR/Cas9 gene editing tool has revolutionized biomedical research and has tremendous potential for use in the cli ...
    Written By: Carmen Leitch
    1
    JUL 08, 2019
    Genetics & Genomics
    A CRISPR System can Edit Only a Defective Copy of a Gene
    A CRISPR System can Edit Only a Defective Copy of a Gene
    With a more precise version of CRISPR/Cas9, researchers altered a single, mutated copy of a gene, leaving the correct on ...
    Written By: Carmen Leitch
    1
    JUL 04, 2019
    Genetics & Genomics
    Combination Therapy Eliminates HIV From Rodent Model
    Combination Therapy Eliminates HIV From Rodent Model
    In 2017, 1.8 million new cases of HIV infection were diagnosed around the world, and around 37 million people live with ...
    Written By: Carmen Leitch
    1
    JUN 24, 2019
    Cell & Molecular Biology
    Using CRISPR to Improve Agriculture
    Using CRISPR to Improve Agriculture
    The CRISPR tool has been modified and refined since it was invented, and now scientists have created another way to use ...
    Written By: Carmen Leitch
    1
    JUN 10, 2019
    Genetics & Genomics
    CRISPR 2.0: Using Transposons to Improve and Expand CRISPR Application
    CRISPR 2.0: Using Transposons to Improve and Expand CRISPR Application
    Source: Science CRISPR-cas9, commonly referred to simply as CRISPR, is a bacterial immune system that was first used as ...
    Written By: Amanda Mikyska
    4
     
     
  • JUN 07, 2019
    Health & Medicine
    In Vivo Tissue Stem Cell and Progenitor Cell Genome Modification
    In Vivo Tissue Stem Cell and Progenitor Cell Genome Modification
    A stem cell, by definition, must be able to self-replicate to make more stem cells and to differentiate into a matu ...
    Written By: Dena Aruta
    1
    JUN 03, 2019
    Genetics & Genomics
    CRISPR Babies May Face Shortened Lifespan
    CRISPR Babies May Face Shortened Lifespan
    Genetic mutations can lead to disease, and scientists have been searching for ways to effectively and safely repair such ...
    Written By: Carmen Leitch
    1
    JUN 01, 2019
    Genetics & Genomics
    How Cas13 Works in Bacteria
    How Cas13 Works in Bacteria
    Cas13 makes a great diagnostic tool, and now researchers know why it naturally makes so many cuts in RNA.
    Written By: Carmen Leitch
    1
    MAY 22, 2019
    Genetics & Genomics
    Insights Into the Cause of Mitral Valve Prolapse
    Insights Into the Cause of Mitral Valve Prolapse
    Most cells in the body have a small appendage called a primary cilium, which is increasingly being recognized for its im ...
    Written By: Carmen Leitch
    1
    MAY 12, 2019
    Genetics & Genomics
    How Long Can We Live For?
    How Long Can We Live For?
    The average human lifespan before the 1900’s was between 30 and 40 years old. It is now between 70 and 85 years ol ...
    Written By: Annie Lennon
    2
     
     
  • MAY 01, 2019
    Cell & Molecular Biology
    Antidote to Deadly Box Jellyfish Venom Developed Using CRISPR
    Antidote to Deadly Box Jellyfish Venom Developed Using CRISPR
    The Australian box jellyfish can be deadly. They are the most venomous marine creature, and one can kill up to 60 people ...
    Written By: Carmen Leitch
    1
    APR 25, 2019
    Genetics & Genomics
    Using Wild Plant Traits to Reduce Pesticide Use
    Using Wild Plant Traits to Reduce Pesticide Use
    Pesticides are a part of agriculture, and while they are important to crop production, some can be detrimental to human ...
    Written By: Carmen Leitch
    1
    APR 24, 2019
    Genetics & Genomics
    Using CRISPR to Create New Model Organisms
    Using CRISPR to Create New Model Organisms
    There are some animal that could offer incredible insight into health and disease, but we've lacked the tools and the kn ...
    Written By: Carmen Leitch
    1
    APR 20, 2019
    Genetics & Genomics
    New Technique Identifies Off-target Effects of CRISPR
    New Technique Identifies Off-target Effects of CRISPR
    CRISPR, holds a lot of promise as a potential therapeutic. But there are hurdles, like the potential for unintended edit ...
    Written By: Carmen Leitch
    2
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