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    CRISPR

    CRISPR is an abbreviation of Clustered Regularly Interspaced Short Palindromic Repeats. The name was minted at a time when the origin and use of the interspacing subsequences were not known. At that time the CRISPRs were described as segments of prokaryotic DNA containing short, repetitive base sequences. In a palindromic repeat, the sequence of nucleotides is the same in both directions. Each repetition is followed by short segments of spacer DNA from previous exposures to foreign DNA (e.g., a virus or plasmid). Small clusters of cas (CRISPR-associated) genes are located next to CRISPR sequences.

    Webinars

    • SEP 07, 2022 | 12:00 PM
      A Universal "Day Zero" Infectious Disease Testing Strategy Exploiting CRISPR-based Sample Depletion and Metagenomic Sequencing with Live Q&A
      A Universal "Day Zero" Infectious Disease Testing Strategy Exploiting...
      The lack of preparedness for detecting the highly infectious SARS-CoV-2 pathogen, the pathogen responsible for the COVID-19 disease, has caused enormous harm to public health and the economy...
      Speaker: Jon Armstrong, MSc
      Presented at: Microbiology Week Virtual Event Series 2022
      Sponsored By: Jumpcode Genomics
      5
      AUG 16, 2022 | 9:00 AM
      A novel and rapid platform to generate gram-level antibodies for diagnostic and therapeutic use
      A novel and rapid platform to generate gram-level antibodies for...
      Date: August 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Combining our rich experience in molecular biology and cell system engineering, GenScript has established the TurboCHO&...
      Speaker: Hao Tan, PhD
      Sponsored By: GenScript
      12
      AUG 10, 2022 | 10:00 AM
      Avoiding hurdles in molecular assay development
      Avoiding hurdles in molecular assay development
      Date: August 10, 2022 Time: 10:00am PDT, 1:00pm EDT The global pandemic has increased focus and scrutiny on molecular diagnostic assay development, resulting in a need for assays that provid...
      Speaker: Naeem Nathoo
      Sponsored By: Thermo Fisher Scientific
      16
      JUN 22, 2022 | 8:00 AM
      Effective application of targeted sequence analysis to propel the biopharmaceutic development continuum from pre-clinical research and biomarker discovery through manufacturing
      Effective application of targeted sequence analysis to propel...
      Biopharmaceutical discovery, development and manufacturing requires the use of genetic analysis across the development continuum. Sanger sequencing and fragment analysis by capillary electro...
      Speaker: Edgar Schreiber, PhD
      Sponsored By: Thermo Fisher Scientific
      9 2
      JUN 21, 2022 | 10:00 AM
      Using cutting-edge stem cell technology to model human cardiac diseases
      Using cutting-edge stem cell technology to model human cardiac...
      Date: June 21, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Human-induced pluripotent stem cell (iPSC) technology allows for “clinical trials in-a-dish” because patient...
      Speaker: Dr. Arianne Caudal
      Sponsored By: Miltenyi Biotec
      19
      JUN 14, 2022 | 9:00 AM
      Improving protein expression in E. coli B-strains using rapid genome engineering
      Improving protein expression in E. coli B-strains using rapid...
      Date: June 14, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) E. coli B-strains, such as BL21, and their derivatives are often used for protein expression due to their optimized amino...
      Speaker: Tyson Shepherd, PhD
      Sponsored By: Inscripta
      16
      JUN 02, 2022 | 8:00 AM
      From pathogen identification to disease prevention and cure: understanding how Sanger sequencing and fragment analysis is powering infectious disease research today
      From pathogen identification to disease prevention and cure: understanding...
      Infectious diseases present a great challenge to global health and its economy. The 2020 SARS- CoV-2 pandemic highlighted the importance of rapid identification, characterization and surveil...
      Speaker: Dr. Archana Gupta
      Sponsored By: Thermo Fisher Scientific
      16
      MAY 25, 2022 | 10:00 AM
      A digital PCR-based protocol to detect and quantify RNA editing events at hotspots
      A digital PCR-based protocol to detect and quantify RNA editing...
      Date: May 25, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Programmable RNA base editors are excellent tools to modify RNA transcripts at precise locations or designated hotspots. P...
      Speaker: Rémi Buisson
      Sponsored By: Thermo Fisher Scientific
      22
      MAY 24, 2022 | 9:00 AM
      A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
      A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
      Date: May 24, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Recent breakthroughs in autologous cellular therapies have generated tremendous excitement for the industry; however, thes...
      Speaker: Andrew Mancini, Ph.D
      Sponsored By: MaxCyte®
      8
      MAY 03, 2022 | 8:00 AM
      Unlocking the genomics of cancer using Sanger sequencing and fragment analysis
      Unlocking the genomics of cancer using Sanger sequencing and fragment...
      Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      15
      APR 19, 2022 | 1:30 PM
      C.E. CREDITS
      Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular Depletion
      Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular...
      Regardless of method, single cell RNA-seq only captures a small fraction of the transcriptome of each cell. Often, this is due to inherent limitations of the methodology as reads ‘drop...
      Speaker: Dante DeAscanis
      Presented at: Genetics Week Virtual Event Series 2022
      Sponsored By: Jumpcode Genomics
      3
      APR 06, 2022 | 5:30 AM
      Leveraging Microscale Automated Bioreactors for the Design and Optimization of Microbial Cell Factories for the Production of Anticancer Drugs Taxol
      Leveraging Microscale Automated Bioreactors for the Design and...
      Currently over 95 % of pharmaceutical products and transport fuels are derived from petroleum. Sustainable alternatives are critical to achieving net-zero emissions without detriment to qual...
      Speaker: Leonardo Rios Solis, PhD
      Presented at: Bioprocessing Virtual Event Series 2022
      2
      APR 05, 2022 | 8:00 AM
      Investigating antimicrobial mechanisms-of-action using automated genome-wide and gene-specific editing
      Investigating antimicrobial mechanisms-of-action using automated...
      Date: April 05, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEDT) Members of the cinnamic acid and stilbenoid chemical families are common intermediates in the production of important bi...
      Speaker: Ali Clark-ElSayed
      Sponsored By: Inscripta
      8
      FEB 23, 2022 | 3:00 PM
      Genetically Engineered Custom Cell Lines for Pre-Clinical Research and Biomanufacturing
      Genetically Engineered Custom Cell Lines for Pre-Clinical Research...
      Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
      Speaker: Stacey Ward, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2022
      Sponsored By: MilliporeSigma
      1
      DEC 09, 2021 | 8:00 AM
      Reprogramming human regulatory T cell specificity with a novel anti-HLA-A2 chimeric antigen receptor
      Reprogramming human regulatory T cell specificity with a novel...
      Date: December 9, 2021 Time: 8:00am (PDT), 11:00am (EDT) Engineering human regulatory T cells (Tregs) with a chimeric antigen receptor (CAR) targeting donorderived human leukocyte antigen (H...
      Speaker: Leonardo Ferreira
      Sponsored By: Thermo Fisher Scientific/Gibco
      5
      DEC 08, 2021 | 9:00 AM
      The MAD7â„¢ nuclease in plant editing: overcoming CRISPR bottlenecks with MAD TiGER
      The MAD7â„¢ nuclease in plant editing: overcoming CRISPR bottlenecks...
      Date: December 9, 2021 Time: 9:00am (PDT), 12:00am (EDT) CRISPR editing has revolutionized plant breeding, and the MAD7 CRISPR nuclease developed by InscriptaTM is democratizing access to CR...
      Speaker: Gabino Sanchez , Ben Mijts
      Sponsored By: Inscripta
      5
      NOV 30, 2021 | 8:00 AM
      ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR T Cell Manufacturing with nS/MARt Vectors
      ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR...
      Date: November 30, 2021 Time: 8:00am (PDT), 11:00am (EDT) The DNA Vector Lab at the German Cancer Research Center (DKFZ) has developed Nano-S/MARt (nS/MARt), a novel DNA Vector platform that...
      Speaker: Matthias Bozza
      Sponsored By: MaxCyte®
      5
      NOV 17, 2021 | 8:00 AM
      Exosomes: From pure isolation to standardized analysis by flow cytometry
      Exosomes: From pure isolation to standardized analysis by flow...
      Date: November 17, 2021 Time: 8:00am (PDT), 11:00am (EDT) From waste disposal to promising biomarkers and therapeutic agents, exosomes and other extracellular vesicles are valuable in resear...
      Speaker: Ariadna Pascual Velazquez , Laura Müller , Stefan Wild, PhD
      Sponsored By: Miltenyi Biotec
      9
      NOV 02, 2021 | 9:00 AM
      Fluorophore fundamentals for flow cytometry
      Fluorophore fundamentals for flow cytometry
      Date: November 2, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Flow cytometry is a powerful technique for the analysis of multiple parameters of individual cells within heterogeneous populations....
      Speaker: Jolene Bradford, MLS, SCYM(ASCP)CM
      Sponsored By: Thermo Fisher Scientific
      15
      OCT 27, 2021 | 8:00 AM
      Easily upgrade your flow cytometry data with brightfield images using the Attune CytPix Flow Cytometer
      Easily upgrade your flow cytometry data with brightfield images...
      Date: October 27, 2021 Time: 8:00am (PDT), 11:00am (EDT) Learn about how brightfield images can take your flow cytometry data to the next level. Join Dr. Cora Chadick, Technical Director, as...
      Speaker: Cora Chadick
      Sponsored By: Thermo Fisher Scientific
      6
      OCT 14, 2021 | 7:00 AM
      Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
      Heterologous Protein Engineering and characterization of native...
      Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
      Speaker: Tyson Shepherd, PhD
      Sponsored By: Inscripta
      22
      OCT 12, 2021 | 8:00 AM
      The growing concern of off-target effects: How to measure and minimize off-target effects in your genome editing experiments.
      The growing concern of off-target effects: How to measure and...
      Date: October 12, 2021 Time: 8:00am (PDT), 11:00am (EDT) CRISPR-Cas9 is a nuclease-based genome editing system which has seen exponential growth in adoption with broad applications from basi...
      Speaker: Pandhita Pochanard
      Sponsored By: Thermo Fisher Scientific/Gibco
      30
      SEP 29, 2021 | 11:59 PM
      Nanoparticle Based Delivery of Gene Editing Enzymes
      Nanoparticle Based Delivery of Gene Editing Enzymes
      Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
      Speaker: Niren Murthy, PhD
      Presented at: CRISPR Virtual Event Series 2021
      2 2
      SEP 29, 2021 | 12:00 PM
      How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
      How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
      Over the past ten years, CRISPR technology has revolutionized genome engineering, as reflected by the recently awarded Nobel Prize. Nevertheless, the process of performing and characterizing...
      Speaker: Domenica Martorana, PhD
      Presented at: CRISPR Virtual Event Series 2021
      Sponsored By: QIAGEN
      1
    SEP 07, 2022 | 12:00 PM
    A Universal "Day Zero" Infectious Disease Testing Strategy Exploiting CRISPR-based Sample Depletion and Metagenomic Sequencing with Live Q&A
    A Universal "Day Zero" Infectious Disease Testing Strategy Exploiting...
    The lack of preparedness for detecting the highly infectious SARS-CoV-2 pathogen, the pathogen responsible for the COVID-19 disease, has caused enormous harm to public health and the economy...
    Speaker: Jon Armstrong, MSc
    Presented at: Microbiology Week Virtual Event Series 2022
    Sponsored By: Jumpcode Genomics
    5
    AUG 16, 2022 | 9:00 AM
    A novel and rapid platform to generate gram-level antibodies for diagnostic and therapeutic use
    A novel and rapid platform to generate gram-level antibodies for...
    Date: August 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Combining our rich experience in molecular biology and cell system engineering, GenScript has established the TurboCHO&...
    Speaker: Hao Tan, PhD
    Sponsored By: GenScript
    12
    AUG 10, 2022 | 10:00 AM
    Avoiding hurdles in molecular assay development
    Avoiding hurdles in molecular assay development
    Date: August 10, 2022 Time: 10:00am PDT, 1:00pm EDT The global pandemic has increased focus and scrutiny on molecular diagnostic assay development, resulting in a need for assays that provid...
    Speaker: Naeem Nathoo
    Sponsored By: Thermo Fisher Scientific
    16
    JUN 22, 2022 | 8:00 AM
    Effective application of targeted sequence analysis to propel the biopharmaceutic development continuum from pre-clinical research and biomarker discovery through manufacturing
    Effective application of targeted sequence analysis to propel...
    Biopharmaceutical discovery, development and manufacturing requires the use of genetic analysis across the development continuum. Sanger sequencing and fragment analysis by capillary electro...
    Speaker: Edgar Schreiber, PhD
    Sponsored By: Thermo Fisher Scientific
    9 2
    JUN 21, 2022 | 10:00 AM
    Using cutting-edge stem cell technology to model human cardiac diseases
    Using cutting-edge stem cell technology to model human cardiac...
    Date: June 21, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Human-induced pluripotent stem cell (iPSC) technology allows for “clinical trials in-a-dish” because patient...
    Speaker: Dr. Arianne Caudal
    Sponsored By: Miltenyi Biotec
    19
     
     
  • JUN 14, 2022 | 9:00 AM
    Improving protein expression in E. coli B-strains using rapid genome engineering
    Improving protein expression in E. coli B-strains using rapid...
    Date: June 14, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) E. coli B-strains, such as BL21, and their derivatives are often used for protein expression due to their optimized amino...
    Speaker: Tyson Shepherd, PhD
    Sponsored By: Inscripta
    16
    JUN 02, 2022 | 8:00 AM
    From pathogen identification to disease prevention and cure: understanding how Sanger sequencing and fragment analysis is powering infectious disease research today
    From pathogen identification to disease prevention and cure: understanding...
    Infectious diseases present a great challenge to global health and its economy. The 2020 SARS- CoV-2 pandemic highlighted the importance of rapid identification, characterization and surveil...
    Speaker: Dr. Archana Gupta
    Sponsored By: Thermo Fisher Scientific
    16
    MAY 25, 2022 | 10:00 AM
    A digital PCR-based protocol to detect and quantify RNA editing events at hotspots
    A digital PCR-based protocol to detect and quantify RNA editing...
    Date: May 25, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Programmable RNA base editors are excellent tools to modify RNA transcripts at precise locations or designated hotspots. P...
    Speaker: Rémi Buisson
    Sponsored By: Thermo Fisher Scientific
    22
    MAY 24, 2022 | 9:00 AM
    A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
    A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
    Date: May 24, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Recent breakthroughs in autologous cellular therapies have generated tremendous excitement for the industry; however, thes...
    Speaker: Andrew Mancini, Ph.D
    Sponsored By: MaxCyte®
    8
    MAY 03, 2022 | 8:00 AM
    Unlocking the genomics of cancer using Sanger sequencing and fragment analysis
    Unlocking the genomics of cancer using Sanger sequencing and fragment...
    Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    15
     
     
  • APR 19, 2022 | 1:30 PM
    C.E. CREDITS
    Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular Depletion
    Boosting Signal-to-Noise in Single Cell RNA-Seq Through Molecular...
    Regardless of method, single cell RNA-seq only captures a small fraction of the transcriptome of each cell. Often, this is due to inherent limitations of the methodology as reads ‘drop...
    Speaker: Dante DeAscanis
    Presented at: Genetics Week Virtual Event Series 2022
    Sponsored By: Jumpcode Genomics
    3
    APR 06, 2022 | 5:30 AM
    Leveraging Microscale Automated Bioreactors for the Design and Optimization of Microbial Cell Factories for the Production of Anticancer Drugs Taxol
    Leveraging Microscale Automated Bioreactors for the Design and...
    Currently over 95 % of pharmaceutical products and transport fuels are derived from petroleum. Sustainable alternatives are critical to achieving net-zero emissions without detriment to qual...
    Speaker: Leonardo Rios Solis, PhD
    Presented at: Bioprocessing Virtual Event Series 2022
    2
    APR 05, 2022 | 8:00 AM
    Investigating antimicrobial mechanisms-of-action using automated genome-wide and gene-specific editing
    Investigating antimicrobial mechanisms-of-action using automated...
    Date: April 05, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEDT) Members of the cinnamic acid and stilbenoid chemical families are common intermediates in the production of important bi...
    Speaker: Ali Clark-ElSayed
    Sponsored By: Inscripta
    8
    FEB 23, 2022 | 3:00 PM
    Genetically Engineered Custom Cell Lines for Pre-Clinical Research and Biomanufacturing
    Genetically Engineered Custom Cell Lines for Pre-Clinical Research...
    Genetically engineered cellular models are an integral part of the drug discovery process from early discovery through clinical biomanufacturing. The various applications of these cellular m...
    Speaker: Stacey Ward, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2022
    Sponsored By: MilliporeSigma
    1
    DEC 09, 2021 | 8:00 AM
    Reprogramming human regulatory T cell specificity with a novel anti-HLA-A2 chimeric antigen receptor
    Reprogramming human regulatory T cell specificity with a novel...
    Date: December 9, 2021 Time: 8:00am (PDT), 11:00am (EDT) Engineering human regulatory T cells (Tregs) with a chimeric antigen receptor (CAR) targeting donorderived human leukocyte antigen (H...
    Speaker: Leonardo Ferreira
    Sponsored By: Thermo Fisher Scientific/Gibco
    5
     
     
  • DEC 08, 2021 | 9:00 AM
    The MAD7â„¢ nuclease in plant editing: overcoming CRISPR bottlenecks with MAD TiGER
    The MAD7â„¢ nuclease in plant editing: overcoming CRISPR bottlenecks...
    Date: December 9, 2021 Time: 9:00am (PDT), 12:00am (EDT) CRISPR editing has revolutionized plant breeding, and the MAD7 CRISPR nuclease developed by InscriptaTM is democratizing access to CR...
    Speaker: Gabino Sanchez , Ben Mijts
    Sponsored By: Inscripta
    5
    NOV 30, 2021 | 8:00 AM
    ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR T Cell Manufacturing with nS/MARt Vectors
    ExPERT Interview: Developing a GMP-Compatible, Large-Scale CAR...
    Date: November 30, 2021 Time: 8:00am (PDT), 11:00am (EDT) The DNA Vector Lab at the German Cancer Research Center (DKFZ) has developed Nano-S/MARt (nS/MARt), a novel DNA Vector platform that...
    Speaker: Matthias Bozza
    Sponsored By: MaxCyte®
    5
    NOV 17, 2021 | 8:00 AM
    Exosomes: From pure isolation to standardized analysis by flow cytometry
    Exosomes: From pure isolation to standardized analysis by flow...
    Date: November 17, 2021 Time: 8:00am (PDT), 11:00am (EDT) From waste disposal to promising biomarkers and therapeutic agents, exosomes and other extracellular vesicles are valuable in resear...
    Speaker: Ariadna Pascual Velazquez , Laura Müller , Stefan Wild, PhD
    Sponsored By: Miltenyi Biotec
    9
    NOV 02, 2021 | 9:00 AM
    Fluorophore fundamentals for flow cytometry
    Fluorophore fundamentals for flow cytometry
    Date: November 2, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Flow cytometry is a powerful technique for the analysis of multiple parameters of individual cells within heterogeneous populations....
    Speaker: Jolene Bradford, MLS, SCYM(ASCP)CM
    Sponsored By: Thermo Fisher Scientific
    15
    OCT 27, 2021 | 8:00 AM
    Easily upgrade your flow cytometry data with brightfield images using the Attune CytPix Flow Cytometer
    Easily upgrade your flow cytometry data with brightfield images...
    Date: October 27, 2021 Time: 8:00am (PDT), 11:00am (EDT) Learn about how brightfield images can take your flow cytometry data to the next level. Join Dr. Cora Chadick, Technical Director, as...
    Speaker: Cora Chadick
    Sponsored By: Thermo Fisher Scientific
    6
     
     
  • OCT 14, 2021 | 7:00 AM
    Heterologous Protein Engineering and characterization of native regulatory elements  in E. coli using Massively Parallel CRISPR Editing
    Heterologous Protein Engineering and characterization of native...
    Date: October 14, 2021 Time: 7:00am (PDT), 10:00am (EDT) Heterologous protein expression in model organisms has many applications, including protein engineering, production of industrial enz...
    Speaker: Tyson Shepherd, PhD
    Sponsored By: Inscripta
    22
    OCT 12, 2021 | 8:00 AM
    The growing concern of off-target effects: How to measure and minimize off-target effects in your genome editing experiments.
    The growing concern of off-target effects: How to measure and...
    Date: October 12, 2021 Time: 8:00am (PDT), 11:00am (EDT) CRISPR-Cas9 is a nuclease-based genome editing system which has seen exponential growth in adoption with broad applications from basi...
    Speaker: Pandhita Pochanard
    Sponsored By: Thermo Fisher Scientific/Gibco
    30
    SEP 29, 2021 | 11:59 PM
    Nanoparticle Based Delivery of Gene Editing Enzymes
    Nanoparticle Based Delivery of Gene Editing Enzymes
    Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
    Speaker: Niren Murthy, PhD
    Presented at: CRISPR Virtual Event Series 2021
    2 2
    SEP 29, 2021 | 12:00 PM
    How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
    How Can You Characterize Your CRISPR Gene Edits Faster and Easier?
    Over the past ten years, CRISPR technology has revolutionized genome engineering, as reflected by the recently awarded Nobel Prize. Nevertheless, the process of performing and characterizing...
    Speaker: Domenica Martorana, PhD
    Presented at: CRISPR Virtual Event Series 2021
    Sponsored By: QIAGEN
    1
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