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    CRISPR

    CRISPR is an abbreviation of Clustered Regularly Interspaced Short Palindromic Repeats. The name was minted at a time when the origin and use of the interspacing subsequences were not known. At that time the CRISPRs were described as segments of prokaryotic DNA containing short, repetitive base sequences. In a palindromic repeat, the sequence of nucleotides is the same in both directions. Each repetition is followed by short segments of spacer DNA from previous exposures to foreign DNA (e.g., a virus or plasmid). Small clusters of cas (CRISPR-associated) genes are located next to CRISPR sequences.

    Webinars

    • FEB 22, 2023 | 5:30 AM
      Novel Bioassays in Picodroplets for Single-Cell Analysis
      Novel Bioassays in Picodroplets for Single-Cell Analysis
      Many current technologies used in drug discovery and preclinical development programmes typically involve multi-step operations, extensive hands-on time, and lengthy liquid handling processe...
      Speaker: Romina Durigon, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2023
      2
      JAN 18, 2023 | 9:00 AM
      Elucidating the composition of CRISPR-Cas12f1 complexes using mass photometry
      Elucidating the composition of CRISPR-Cas12f1 complexes using...
      Date: January 18, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) CRISPR-Cas systems are widely used in genome engineering applications. They contain RNA-guided ribonucleoprotein (RNP)...
      Speaker: Selgar Henkel-Heinecke
      Sponsored By: Refeyn
      13
      DEC 13, 2022 | 8:00 AM
      Assessing CRISPR On-Target Editing and Structural Changes with UDiTaSâ„¢ using Tagifyâ„¢ Reagents
      Assessing CRISPR On-Target Editing and Structural Changes with...
      Date: December 13, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Understanding the diversity of repair outcomes after introducing a genomic cut is essential for realizing the therapeu...
      Speaker: Jack Leonard, PhD , Georgia Giannoukos, PhD
      Sponsored By: seqWell
      13
      NOV 02, 2022 | 7:30 AM
      Keynote Presentation: Engineered LwaCas13a with Enhanced Collateral Activity for Nucleic Acid Detection
      Keynote Presentation: Engineered LwaCas13a with Enhanced Collateral...
      Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein 13 (Cas13) has been rapidly developed for nucleic-acid-based diagnostics by using its chara...
      Speaker: Xue Sherry Gao, PhD
      Presented at: CRISPR Virtual Event Series 2022
      5
      NOV 02, 2022 | 6:00 AM
      Detecting Viruses with CRISPR
      Detecting Viruses with CRISPR
      CRISPR has revolutionized the biosciences over the past decade. The RNA-targeting CRISPR effector protein Cas13, discovered in 2016, opened up a myriad of new applications for CRISPR-based t...
      Speaker: Cameron Myhrvold, PhD
      Presented at: CRISPR Virtual Event Series 2022
      2
      OCT 13, 2022 | 9:00 AM
      Smart EPU with Embedded CryoSPARCâ„¢ Live: integrated real-time data analysis for high-quality 3D protein structures
      Smart EPU with Embedded CryoSPARCâ„¢ Live: integrated real-time...
      First Broadcast: Date: October 12, 2022 Time: 8:00am PDT, 11:00am EDT Second Broadcast: Date: October 12, 2022 Time: 9:00am SGT The new Embedded CryoSPARC Live, now fully integrated with t...
      Speaker: Julio Ortiz , Edward Pryor, PhD , Ali Punjani
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific
      10
      OCT 06, 2022 | 5:00 PM
      Driving genetic biomarker discovery for detecting and monitoring tumor pathogenesis
      Driving genetic biomarker discovery for detecting and monitoring...
      Genetic biomarkers have become increasingly important for disease prediction, early disease detection and progression, and options for intervention. Tumor biopsies are commonly used as sourc...
      Speaker: Dr. Archana Gupta
      Sponsored By: Thermo Fisher Scientific
      11
      OCT 05, 2022 | 9:00 PM
      Genome editing: Disease modelling to novel therapeutics
      Genome editing: Disease modelling to novel therapeutics
      Date: October 6, 2022 Time: Time: 9:30am IST, 12:00pm SGT, 1:00pm JST, KThe discovery of the CRISPR/Cas9 system has transformed research and now allows straightforward alterations in the geno...
      Speaker: Erik Willems, PhD , Jason Potter, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      23 2
      OCT 04, 2022 | 9:00 AM
      Enabling fully automated NGS sample preparation using digital microfluidics
      Enabling fully automated NGS sample preparation using digital...
      Date: October 04, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The Miro Canvas is a new platform which enables full walkaway automation of complex next generation sequencing (NGS) s...
      Speaker: Dr. Jonathan Levine , Dr. Fay Christodoulou
      Sponsored By: Miroculus
      13
      OCT 04, 2022 | 7:00 AM
      Tools & Strategies for Implementing iPSC-based Cell Models for Neurodegenerative Disease Drug Discovery
      Tools & Strategies for Implementing iPSC-based Cell Models for...
      Date: October 04, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) The ability to derive induced pluripotent stem cells (iPSCs) from differentiated cell types such as fibroblasts, has r...
      Speaker: Benjamin Schmid , Peter Reinhardt
      Sponsored By: Bioneer A/S
      13
      SEP 28, 2022 | 7:00 AM
      From Bench to Bedside: Targeted Gene Editing
      From Bench to Bedside: Targeted Gene Editing
      Date: September 28, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) CRISPR/Cas gene editing technology has rapidly evolved over the last decade. Its versatility extends from creating t...
      Speaker: Jennifer Bennett, PhD
      Sponsored By: MilliporeSigma
      20
      SEP 27, 2022 | 8:00 AM
      Efficient and Rapid Discovery of Novel Temperature Sensitive Alleles with the Onyx® Digital Genome Engineering Platform
      Efficient and Rapid Discovery of Novel Temperature Sensitive Alleles...
      Date: September 27, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Temperature sensitive (TS) alleles are mutations in essential genes that allow for growth at permissive temperatures...
      Speaker: Randy Lacey
      Sponsored By: Inscripta
      10 2
      SEP 22, 2022 | 9:00 AM
      Human proteomics: from the operating room to the lab and back
      Human proteomics: from the operating room to the lab and back
      Date: September 22, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Optimizing platforms for surgical specimen collection and deep human phenotyping was used to enhance protein biomarke...
      Speaker: Vinit Mahajan M.D., Ph.D.
      Sponsored By: SomaLogic
      17
      SEP 15, 2022 | 9:00 AM
      Advances and Challenges in Targeting Kinases in Cancer Therapeutics
      Advances and Challenges in Targeting Kinases in Cancer Therapeutics
      Date: September 15, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Tyrosine kinases, a ubiquitous and diverse family of enzymes, are of considerable clinical interest because they dir...
      Speaker: Aishath Shanaz Naeem , Veronique Baron
      Sponsored By: BPS Bioscience
      9
      SEP 07, 2022 | 12:00 PM
      A Universal "Day Zero" Infectious Disease Testing Strategy Exploiting CRISPR-based Sample Depletion and Metagenomic Sequencing with Live Q&A
      A Universal "Day Zero" Infectious Disease Testing Strategy Exploiting...
      The lack of preparedness for detecting the highly infectious SARS-CoV-2 pathogen, the pathogen responsible for the COVID-19 disease, has caused enormous harm to public health and the economy...
      Speaker: Jon Armstrong, MSc
      Presented at: Microbiology Week Virtual Event Series 2022
      Sponsored By: Jumpcode Genomics
      5
      AUG 16, 2022 | 9:00 AM
      A novel and rapid platform to generate gram-level antibodies for diagnostic and therapeutic use
      A novel and rapid platform to generate gram-level antibodies for...
      Date: August 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Combining our rich experience in molecular biology and cell system engineering, GenScript has established the TurboCHO&...
      Speaker: Hao Tan, PhD
      Sponsored By: GenScript
      12
      AUG 10, 2022 | 10:00 AM
      Avoiding hurdles in molecular assay development
      Avoiding hurdles in molecular assay development
      Date: August 10, 2022 Time: 10:00am PDT, 1:00pm EDT The global pandemic has increased focus and scrutiny on molecular diagnostic assay development, resulting in a need for assays that provid...
      Speaker: Naeem Nathoo
      Sponsored By: Thermo Fisher Scientific
      16
      JUN 22, 2022 | 8:00 AM
      Effective application of targeted sequence analysis to propel the biopharmaceutic development continuum from pre-clinical research and biomarker discovery through manufacturing
      Effective application of targeted sequence analysis to propel...
      Biopharmaceutical discovery, development and manufacturing requires the use of genetic analysis across the development continuum. Sanger sequencing and fragment analysis by capillary electro...
      Speaker: Edgar Schreiber, PhD
      Sponsored By: Thermo Fisher Scientific
      9 2
      JUN 21, 2022 | 10:00 AM
      Using cutting-edge stem cell technology to model human cardiac diseases
      Using cutting-edge stem cell technology to model human cardiac...
      Date: June 21, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Human-induced pluripotent stem cell (iPSC) technology allows for “clinical trials in-a-dish” because patient...
      Speaker: Dr. Arianne Caudal
      Sponsored By: Miltenyi Biotec
      19
      JUN 14, 2022 | 9:00 AM
      Improving protein expression in E. coli B-strains using rapid genome engineering
      Improving protein expression in E. coli B-strains using rapid...
      Date: June 14, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) E. coli B-strains, such as BL21, and their derivatives are often used for protein expression due to their optimized amino...
      Speaker: Tyson Shepherd, PhD
      Sponsored By: Inscripta
      16
      JUN 02, 2022 | 8:00 AM
      From pathogen identification to disease prevention and cure: understanding how Sanger sequencing and fragment analysis is powering infectious disease research today
      From pathogen identification to disease prevention and cure: understanding...
      Infectious diseases present a great challenge to global health and its economy. The 2020 SARS- CoV-2 pandemic highlighted the importance of rapid identification, characterization and surveil...
      Speaker: Dr. Archana Gupta
      Sponsored By: Thermo Fisher Scientific
      16
      MAY 25, 2022 | 10:00 AM
      A digital PCR-based protocol to detect and quantify RNA editing events at hotspots
      A digital PCR-based protocol to detect and quantify RNA editing...
      Date: May 25, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Programmable RNA base editors are excellent tools to modify RNA transcripts at precise locations or designated hotspots. P...
      Speaker: Rémi Buisson
      Sponsored By: Thermo Fisher Scientific
      22
      MAY 24, 2022 | 9:00 AM
      A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
      A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
      Date: May 24, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Recent breakthroughs in autologous cellular therapies have generated tremendous excitement for the industry; however, thes...
      Speaker: Andrew Mancini, Ph.D
      Sponsored By: MaxCyte®
      8
      MAY 03, 2022 | 8:00 AM
      Unlocking the genomics of cancer using Sanger sequencing and fragment analysis
      Unlocking the genomics of cancer using Sanger sequencing and fragment...
      Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
      15
    FEB 22, 2023 | 5:30 AM
    Novel Bioassays in Picodroplets for Single-Cell Analysis
    Novel Bioassays in Picodroplets for Single-Cell Analysis
    Many current technologies used in drug discovery and preclinical development programmes typically involve multi-step operations, extensive hands-on time, and lengthy liquid handling processe...
    Speaker: Romina Durigon, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2023
    2
    JAN 18, 2023 | 9:00 AM
    Elucidating the composition of CRISPR-Cas12f1 complexes using mass photometry
    Elucidating the composition of CRISPR-Cas12f1 complexes using...
    Date: January 18, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) CRISPR-Cas systems are widely used in genome engineering applications. They contain RNA-guided ribonucleoprotein (RNP)...
    Speaker: Selgar Henkel-Heinecke
    Sponsored By: Refeyn
    13
    DEC 13, 2022 | 8:00 AM
    Assessing CRISPR On-Target Editing and Structural Changes with UDiTaSâ„¢ using Tagifyâ„¢ Reagents
    Assessing CRISPR On-Target Editing and Structural Changes with...
    Date: December 13, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Understanding the diversity of repair outcomes after introducing a genomic cut is essential for realizing the therapeu...
    Speaker: Jack Leonard, PhD , Georgia Giannoukos, PhD
    Sponsored By: seqWell
    13
    NOV 02, 2022 | 7:30 AM
    Keynote Presentation: Engineered LwaCas13a with Enhanced Collateral Activity for Nucleic Acid Detection
    Keynote Presentation: Engineered LwaCas13a with Enhanced Collateral...
    Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein 13 (Cas13) has been rapidly developed for nucleic-acid-based diagnostics by using its chara...
    Speaker: Xue Sherry Gao, PhD
    Presented at: CRISPR Virtual Event Series 2022
    5
    NOV 02, 2022 | 6:00 AM
    Detecting Viruses with CRISPR
    Detecting Viruses with CRISPR
    CRISPR has revolutionized the biosciences over the past decade. The RNA-targeting CRISPR effector protein Cas13, discovered in 2016, opened up a myriad of new applications for CRISPR-based t...
    Speaker: Cameron Myhrvold, PhD
    Presented at: CRISPR Virtual Event Series 2022
    2
     
     
  • OCT 13, 2022 | 9:00 AM
    Smart EPU with Embedded CryoSPARCâ„¢ Live: integrated real-time data analysis for high-quality 3D protein structures
    Smart EPU with Embedded CryoSPARCâ„¢ Live: integrated real-time...
    First Broadcast: Date: October 12, 2022 Time: 8:00am PDT, 11:00am EDT Second Broadcast: Date: October 12, 2022 Time: 9:00am SGT The new Embedded CryoSPARC Live, now fully integrated with t...
    Speaker: Julio Ortiz , Edward Pryor, PhD , Ali Punjani
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific
    10
    OCT 06, 2022 | 5:00 PM
    Driving genetic biomarker discovery for detecting and monitoring tumor pathogenesis
    Driving genetic biomarker discovery for detecting and monitoring...
    Genetic biomarkers have become increasingly important for disease prediction, early disease detection and progression, and options for intervention. Tumor biopsies are commonly used as sourc...
    Speaker: Dr. Archana Gupta
    Sponsored By: Thermo Fisher Scientific
    11
    OCT 05, 2022 | 9:00 PM
    Genome editing: Disease modelling to novel therapeutics
    Genome editing: Disease modelling to novel therapeutics
    Date: October 6, 2022 Time: Time: 9:30am IST, 12:00pm SGT, 1:00pm JST, KThe discovery of the CRISPR/Cas9 system has transformed research and now allows straightforward alterations in the geno...
    Speaker: Erik Willems, PhD , Jason Potter, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    23 2
    OCT 04, 2022 | 9:00 AM
    Enabling fully automated NGS sample preparation using digital microfluidics
    Enabling fully automated NGS sample preparation using digital...
    Date: October 04, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The Miro Canvas is a new platform which enables full walkaway automation of complex next generation sequencing (NGS) s...
    Speaker: Dr. Jonathan Levine , Dr. Fay Christodoulou
    Sponsored By: Miroculus
    13
    OCT 04, 2022 | 7:00 AM
    Tools & Strategies for Implementing iPSC-based Cell Models for Neurodegenerative Disease Drug Discovery
    Tools & Strategies for Implementing iPSC-based Cell Models for...
    Date: October 04, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) The ability to derive induced pluripotent stem cells (iPSCs) from differentiated cell types such as fibroblasts, has r...
    Speaker: Benjamin Schmid , Peter Reinhardt
    Sponsored By: Bioneer A/S
    13
     
     
  • SEP 28, 2022 | 7:00 AM
    From Bench to Bedside: Targeted Gene Editing
    From Bench to Bedside: Targeted Gene Editing
    Date: September 28, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) CRISPR/Cas gene editing technology has rapidly evolved over the last decade. Its versatility extends from creating t...
    Speaker: Jennifer Bennett, PhD
    Sponsored By: MilliporeSigma
    20
    SEP 27, 2022 | 8:00 AM
    Efficient and Rapid Discovery of Novel Temperature Sensitive Alleles with the Onyx® Digital Genome Engineering Platform
    Efficient and Rapid Discovery of Novel Temperature Sensitive Alleles...
    Date: September 27, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Temperature sensitive (TS) alleles are mutations in essential genes that allow for growth at permissive temperatures...
    Speaker: Randy Lacey
    Sponsored By: Inscripta
    10 2
    SEP 22, 2022 | 9:00 AM
    Human proteomics: from the operating room to the lab and back
    Human proteomics: from the operating room to the lab and back
    Date: September 22, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Optimizing platforms for surgical specimen collection and deep human phenotyping was used to enhance protein biomarke...
    Speaker: Vinit Mahajan M.D., Ph.D.
    Sponsored By: SomaLogic
    17
    SEP 15, 2022 | 9:00 AM
    Advances and Challenges in Targeting Kinases in Cancer Therapeutics
    Advances and Challenges in Targeting Kinases in Cancer Therapeutics
    Date: September 15, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Tyrosine kinases, a ubiquitous and diverse family of enzymes, are of considerable clinical interest because they dir...
    Speaker: Aishath Shanaz Naeem , Veronique Baron
    Sponsored By: BPS Bioscience
    9
    SEP 07, 2022 | 12:00 PM
    A Universal "Day Zero" Infectious Disease Testing Strategy Exploiting CRISPR-based Sample Depletion and Metagenomic Sequencing with Live Q&A
    A Universal "Day Zero" Infectious Disease Testing Strategy Exploiting...
    The lack of preparedness for detecting the highly infectious SARS-CoV-2 pathogen, the pathogen responsible for the COVID-19 disease, has caused enormous harm to public health and the economy...
    Speaker: Jon Armstrong, MSc
    Presented at: Microbiology Week Virtual Event Series 2022
    Sponsored By: Jumpcode Genomics
    5
     
     
  • AUG 16, 2022 | 9:00 AM
    A novel and rapid platform to generate gram-level antibodies for diagnostic and therapeutic use
    A novel and rapid platform to generate gram-level antibodies for...
    Date: August 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Combining our rich experience in molecular biology and cell system engineering, GenScript has established the TurboCHO&...
    Speaker: Hao Tan, PhD
    Sponsored By: GenScript
    12
    AUG 10, 2022 | 10:00 AM
    Avoiding hurdles in molecular assay development
    Avoiding hurdles in molecular assay development
    Date: August 10, 2022 Time: 10:00am PDT, 1:00pm EDT The global pandemic has increased focus and scrutiny on molecular diagnostic assay development, resulting in a need for assays that provid...
    Speaker: Naeem Nathoo
    Sponsored By: Thermo Fisher Scientific
    16
    JUN 22, 2022 | 8:00 AM
    Effective application of targeted sequence analysis to propel the biopharmaceutic development continuum from pre-clinical research and biomarker discovery through manufacturing
    Effective application of targeted sequence analysis to propel...
    Biopharmaceutical discovery, development and manufacturing requires the use of genetic analysis across the development continuum. Sanger sequencing and fragment analysis by capillary electro...
    Speaker: Edgar Schreiber, PhD
    Sponsored By: Thermo Fisher Scientific
    9 2
    JUN 21, 2022 | 10:00 AM
    Using cutting-edge stem cell technology to model human cardiac diseases
    Using cutting-edge stem cell technology to model human cardiac...
    Date: June 21, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Human-induced pluripotent stem cell (iPSC) technology allows for “clinical trials in-a-dish” because patient...
    Speaker: Dr. Arianne Caudal
    Sponsored By: Miltenyi Biotec
    19
    JUN 14, 2022 | 9:00 AM
    Improving protein expression in E. coli B-strains using rapid genome engineering
    Improving protein expression in E. coli B-strains using rapid...
    Date: June 14, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) E. coli B-strains, such as BL21, and their derivatives are often used for protein expression due to their optimized amino...
    Speaker: Tyson Shepherd, PhD
    Sponsored By: Inscripta
    16
     
     
  • JUN 02, 2022 | 8:00 AM
    From pathogen identification to disease prevention and cure: understanding how Sanger sequencing and fragment analysis is powering infectious disease research today
    From pathogen identification to disease prevention and cure: understanding...
    Infectious diseases present a great challenge to global health and its economy. The 2020 SARS- CoV-2 pandemic highlighted the importance of rapid identification, characterization and surveil...
    Speaker: Dr. Archana Gupta
    Sponsored By: Thermo Fisher Scientific
    16
    MAY 25, 2022 | 10:00 AM
    A digital PCR-based protocol to detect and quantify RNA editing events at hotspots
    A digital PCR-based protocol to detect and quantify RNA editing...
    Date: May 25, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Programmable RNA base editors are excellent tools to modify RNA transcripts at precise locations or designated hotspots. P...
    Speaker: Rémi Buisson
    Sponsored By: Thermo Fisher Scientific
    22
    MAY 24, 2022 | 9:00 AM
    A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
    A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
    Date: May 24, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Recent breakthroughs in autologous cellular therapies have generated tremendous excitement for the industry; however, thes...
    Speaker: Andrew Mancini, Ph.D
    Sponsored By: MaxCyte®
    8
    MAY 03, 2022 | 8:00 AM
    Unlocking the genomics of cancer using Sanger sequencing and fragment analysis
    Unlocking the genomics of cancer using Sanger sequencing and fragment...
    Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    15
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