CRISPR is an abbreviation of Clustered Regularly Interspaced Short Palindromic Repeats. The name was minted at a time when the origin and use of the interspacing subsequences were not known. At that time the CRISPRs were described as segments of prokaryotic DNA containing short, repetitive base sequences. In a palindromic repeat, the sequence of nucleotides is the same in both directions. Each repetition is followed by short segments of spacer DNA from previous exposures to foreign DNA (e.g., a virus or plasmid). Small clusters of cas (CRISPR-associated) genes are located next to CRISPR sequences.
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Date: December 13, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) Understanding the diversity of repair outcomes after introducing a genomic cut is essential for realizing the therapeu...
Clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein 13 (Cas13) has been rapidly developed for nucleic-acid-based diagnostics by using its chara...
CRISPR has revolutionized the biosciences over the past decade. The RNA-targeting CRISPR effector protein Cas13, discovered in 2016, opened up a myriad of new applications for CRISPR-based t...
First Broadcast: Date: October 12, 2022 Time: 8:00am PDT, 11:00am EDT Second Broadcast: Date: October 12, 2022 Time: 9:00am SGT The new Embedded CryoSPARC Live, now fully integrated with t...
Genetic biomarkers have become increasingly important for disease prediction, early disease detection and progression, and options for intervention. Tumor biopsies are commonly used as sourc...
Date: October 6, 2022 Time: Time: 9:30am IST, 12:00pm SGT, 1:00pm JST, KThe discovery of the CRISPR/Cas9 system has transformed research and now allows straightforward alterations in the geno...
Date: October 04, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The Miro Canvas is a new platform which enables full walkaway automation of complex next generation sequencing (NGS) s...
Date: October 04, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) The ability to derive induced pluripotent stem cells (iPSCs) from differentiated cell types such as fibroblasts, has r...
Date: September 28, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) CRISPR/Cas gene editing technology has rapidly evolved over the last decade. Its versatility extends from creating t...
Date: September 27, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Temperature sensitive (TS) alleles are mutations in essential genes that allow for growth at permissive temperatures...
Date: September 22, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Optimizing platforms for surgical specimen collection and deep human phenotyping was used to enhance protein biomarke...
Date: September 15, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Tyrosine kinases, a ubiquitous and diverse family of enzymes, are of considerable clinical interest because they dir...
The lack of preparedness for detecting the highly infectious SARS-CoV-2 pathogen, the pathogen responsible for the COVID-19 disease, has caused enormous harm to public health and the economy...
Date: August 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Combining our rich experience in molecular biology and cell system engineering, GenScript has established the TurboCHO&...
Date: August 10, 2022 Time: 10:00am PDT, 1:00pm EDT The global pandemic has increased focus and scrutiny on molecular diagnostic assay development, resulting in a need for assays that provid...
Biopharmaceutical discovery, development and manufacturing requires the use of genetic analysis across the development continuum. Sanger sequencing and fragment analysis by capillary electro...
Date: June 21, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Human-induced pluripotent stem cell (iPSC) technology allows for “clinical trials in-a-dish” because patient...
Date: June 14, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) E. coli B-strains, such as BL21, and their derivatives are often used for protein expression due to their optimized amino...
Infectious diseases present a great challenge to global health and its economy. The 2020 SARS- CoV-2 pandemic highlighted the importance of rapid identification, characterization and surveil...
Date: May 25, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Programmable RNA base editors are excellent tools to modify RNA transcripts at precise locations or designated hotspots. P...
Date: May 24, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Recent breakthroughs in autologous cellular therapies have generated tremendous excitement for the industry; however, thes...
Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
APR 19, 2022 | 1:30 PM
C.E. CREDITS
Regardless of method, single cell RNA-seq only captures a small fraction of the transcriptome of each cell. Often, this is due to inherent limitations of the methodology as reads ‘drop...
Currently over 95 % of pharmaceutical products and transport fuels are derived from petroleum. Sustainable alternatives are critical to achieving net-zero emissions without detriment to qual...