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Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
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DEC 04, 2017Drug Discovery & Development
What is drug discovery and what does it entailWritten By: Courtney SchaalDEC 01, 2017Drug Discovery & Development
Considerations and Limitations of High Throughput Screening for Drug DiscoveryWritten By: Courtney SchaalNOV 30, 2017Cell & Molecular Biology
Scientists succeeded in creating bacteria that carry two additional nucleotide bases in their genetic code.Written By: Carmen LeitchNOV 29, 2017Drug Discovery & Development
New evidence that chromatin rearranges in a reversible manner in drug resistant cancer cellsWritten By: Courtney SchaalNOV 28, 2017Immunology
Macular degeneration is considered to be an incurable eye disease, but a new discovery from University of Virginia scien ...Written By: Kara MarkerNOV 24, 2017Immunology
The majority of drugs available for people with autoimmune diseases are only designed to alleviate symptoms, as opposed ...Written By: Kara MarkerNOV 22, 2017Drug Discovery & Development
The use of bispecific antibodies in cancer immunotherapiesWritten By: Courtney SchaalNOV 21, 2017Drug Discovery & Development
The blood brain barrier poses a challenge to drug discovery efforts when targeting the brainWritten By: Courtney SchaalNOV 21, 2017Drug Discovery & Development
We are using 3D organoids to unravel new therapies for a broad spectrum of human diseaseWritten By: Courtney SchaalNOV 18, 2017Drug Discovery & Development
PSMA, currently used for successful in prostate cancer, is found to have potential utility for diagnostics and therapuet ...Written By: Courtney SchaalNOV 18, 2017Drug Discovery & Development
Scientists in Europe Use Genetically Modified Patient Stem Cells to Graft Whole Body SkinWritten By: Courtney SchaalNOV 16, 2017Health & Medicine
Classic science fiction movies and even cartoons from decades ago predicted flying cars and food replicators and apartme ...Written By: Brenda Kelley KimNOV 12, 2017Drug Discovery & Development
Bacteria has continued to evolve, becoming resistant to antibiotics, but scientists have found a screen to help combat t ...Written By: Courtney SchaalNOV 12, 2017Drug Discovery & Development
Repurposing already approved drugs for new therapeutic indications to expedite new drugs being used in the clinicWritten By: Courtney SchaalNOV 06, 2017Genetics & Genomics
Chromatin remodeling is related to Fragile X Syndrome and autism; it now presents a great therapeutic target for treatme ...Written By: Carmen LeitchNOV 05, 2017Cell & Molecular Biology
Nusinersen may be a life-changer for patients with spinal muscular atrophy (SMA) type 1.Written By: Carmen LeitchOCT 31, 2017Genetics & Genomics
Researchers are learning more about the normal function of the gene that is the most common genetic cause of late-onset ...Written By: Carmen LeitchOCT 31, 2017Immunology
People with type 2 diabetes are particularly prone to ulcers on the bottom of the foot, which can increase the risk of d ...Written By: Kara MarkerOCT 21, 2017Genetics & Genomics
Scientists have learned more about a genetic disorder that affects the liver, revealing potential new therapeutic avenue ...Written By: Carmen LeitchOCT 20, 2017Clinical & Molecular DX
Using cutting-edge gene-editing technologies, Japanese scientists have modified hens to produce eggs that now contain a ...OCT 19, 2017Health & Medicine
For the first time, researchers dare to suggest they may have found a functional cure for HIV, the viral infection that ...Written By: Kara MarkerOCT 16, 2017Videos
Scientists have solved the mystery of the connection between high cholesterol levels and increased rates of breast cance ...Written By: Kara MarkerOCT 13, 2017Clinical & Molecular DX
Stanford scientists just discovered a new way to make large quantities of a precious drug that holds potential as treatm ...OCT 10, 2017Drug Discovery & Development
After nearly a decade of searching, scientists from the Albert Einstein College of Medicine have found a molecule that k ...
DEC 04, 2017
Drug Discovery & Development
What is drug discovery and what does it entail
Written By:
Courtney Schaal
DEC 01, 2017
Drug Discovery & Development
Considerations and Limitations of High Throughput Screening for Drug Discovery
Written By:
Courtney Schaal
NOV 30, 2017
Cell & Molecular Biology
Scientists succeeded in creating bacteria that carry two additional nucleotide bases in their genetic code.
Written By:
Carmen Leitch
NOV 29, 2017
Drug Discovery & Development
New evidence that chromatin rearranges in a reversible manner in drug resistant cancer cells
Written By:
Courtney Schaal
NOV 28, 2017
Immunology
Macular degeneration is considered to be an incurable eye disease, but a new discovery from University of Virginia scien
...
Written By:
Kara Marker
NOV 24, 2017
Immunology
The majority of drugs available for people with autoimmune diseases are only designed to alleviate symptoms, as opposed
...
Written By:
Kara Marker
NOV 22, 2017
Drug Discovery & Development
The use of bispecific antibodies in cancer immunotherapies
Written By:
Courtney Schaal
NOV 21, 2017
Drug Discovery & Development
The blood brain barrier poses a challenge to drug discovery efforts when targeting the brain
Written By:
Courtney Schaal
NOV 21, 2017
Drug Discovery & Development
We are using 3D organoids to unravel new therapies for a broad spectrum of human disease
Written By:
Courtney Schaal
NOV 18, 2017
Drug Discovery & Development
PSMA, currently used for successful in prostate cancer, is found to have potential utility for diagnostics and therapuet
...
Written By:
Courtney Schaal
NOV 18, 2017
Drug Discovery & Development
Scientists in Europe Use Genetically Modified Patient Stem Cells to Graft Whole Body Skin
Written By:
Courtney Schaal
NOV 16, 2017
Health & Medicine
Classic science fiction movies and even cartoons from decades ago predicted flying cars and food replicators and apartme
...
Written By:
Brenda Kelley Kim
NOV 12, 2017
Drug Discovery & Development
Bacteria has continued to evolve, becoming resistant to antibiotics, but scientists have found a screen to help combat t
...
Written By:
Courtney Schaal
NOV 12, 2017
Drug Discovery & Development
Repurposing already approved drugs for new therapeutic indications to expedite new drugs being used in the clinic
Written By:
Courtney Schaal
NOV 06, 2017
Genetics & Genomics
Chromatin remodeling is related to Fragile X Syndrome and autism; it now presents a great therapeutic target for treatme
...
Written By:
Carmen Leitch
NOV 05, 2017
Cell & Molecular Biology
Nusinersen may be a life-changer for patients with spinal muscular atrophy (SMA) type 1.
Written By:
Carmen Leitch
OCT 31, 2017
Genetics & Genomics
Researchers are learning more about the normal function of the gene that is the most common genetic cause of late-onset
...
Written By:
Carmen Leitch
OCT 31, 2017
Immunology
People with type 2 diabetes are particularly prone to ulcers on the bottom of the foot, which can increase the risk of d
...
Written By:
Kara Marker
OCT 21, 2017
Genetics & Genomics
Scientists have learned more about a genetic disorder that affects the liver, revealing potential new therapeutic avenue
...
Written By:
Carmen Leitch
OCT 20, 2017
Clinical & Molecular DX
Using cutting-edge gene-editing technologies, Japanese scientists have modified hens to produce eggs that now contain a
...
OCT 19, 2017
Health & Medicine
For the first time, researchers dare to suggest they may have found a functional cure for HIV, the viral infection that
...
Written By:
Kara Marker
OCT 16, 2017
Videos
Scientists have solved the mystery of the connection between high cholesterol levels and increased rates of breast cance
...
Written By:
Kara Marker
OCT 13, 2017
Clinical & Molecular DX
Stanford scientists just discovered a new way to make large quantities of a precious drug that holds potential as treatm
...
OCT 10, 2017
Drug Discovery & Development
After nearly a decade of searching, scientists from the Albert Einstein College of Medicine have found a molecule that k
...