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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

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      OCT 01, 2017
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      Antonie van Leeuwenhoek & the Discovery of Bacteria
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      SEP 02, 2017
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      JUL 26, 2017
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      JUL 20, 2017
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      JUL 17, 2017
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      JUL 16, 2017
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      JUL 11, 2017
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      JUL 04, 2017
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      JUN 23, 2017
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      JUN 13, 2017
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      JUN 07, 2017
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      MAY 31, 2017
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      MAY 30, 2017
      Health & Medicine
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      Genetic Study of Psoriasis Reveals Clues About Disease Causation
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      MAY 28, 2017
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      MAY 22, 2017
      Neuroscience
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      MAY 17, 2017
      Cell & Molecular Biology
      New Connection Between Receptors Discovered in the Brain
      New Connection Between Receptors Discovered in the Brain
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      MAY 09, 2017
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      MAY 05, 2017
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      APR 20, 2017
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    OCT 03, 2017
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    An Open Source Microscope for Imaging Live, Unrestrained Zebrafish
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    2
    OCT 01, 2017
    Videos
    Antonie van Leeuwenhoek & the Discovery of Bacteria
    Antonie van Leeuwenhoek & the Discovery of Bacteria
    Bacteria were first reported on September 17, 1683, by Dutch scientist Antonie van Leeuwenhoek, who had observed single- ...
    Written By: Carmen Leitch
    3
    SEP 02, 2017
    Cell & Molecular Biology
    Asthma Drug Linked to Reduced Parkinson's Risk
    Asthma Drug Linked to Reduced Parkinson's Risk
    An epidemiological study was paired with laboratory results to find what might have been the cause of this effect.
    Written By: Carmen Leitch
    3
    JUL 26, 2017
    Cell & Molecular Biology
    A Better way to Develop new Drugs
    A Better way to Develop new Drugs
    Finding new drugs can be challenging, but researchers are using a methodical approach to identify good candidates.
    Written By: Carmen Leitch
    2
    JUL 20, 2017
    Microbiology
    Municipal Wastewater Could be a Source for new Antimicrobials
    Municipal Wastewater Could be a Source for new Antimicrobials
    As antibiotic-resistance among pathogens becomes an ever-bigger problem, the pressure is on to find new antibiotics.
    Written By: Carmen Leitch
    1
     
     
  • JUL 17, 2017
    Clinical & Molecular DX
    Scientists Stumble on a Way to Find New Antibiotics
    Scientists Stumble on a Way to Find New Antibiotics
    Science sometimes happens by accident. And happily, sometimes these accidents have the potential to radically transform ...
    Written By: Xuan Pham
    2
    JUL 16, 2017
    Cell & Molecular Biology
    Research on Neurological Tumor Development Reveals Drug Target
    Research on Neurological Tumor Development Reveals Drug Target
    NF2 affects thousands of people. New research could help bring treatment to those patients.
    Written By: Carmen Leitch
    2 1
    JUL 11, 2017
    Microbiology
    Yogurt Isn't Just a Probiotic - Its Unique Proteins Kill Bad Bacteria
    Yogurt Isn't Just a Probiotic - Its Unique Proteins Kill Bad Bacteria
    Yogurt is more than an excellent source of protein, calcium, and gut-healthy probiotic bacteria. A protein isolated from ...
    Written By: Invisiverse Puccio
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    JUL 10, 2017
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    JUL 04, 2017
    Health & Medicine
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  • JUN 23, 2017
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    Evolutionary Insight - From Parasitic Wasps
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    Written By: Carmen Leitch
    1
    JUN 17, 2017
    Microbiology
    New, Powerful Antibiotic Found in Soil
    New, Powerful Antibiotic Found in Soil
    Soil has previously been the source of effective antibiotics, researchers are excited about the latest drug discovery ha ...
    Written By: Carmen Leitch
    1 1
    JUN 16, 2017
    Cancer
    Vitamin C & Antibiotics: A Potent Duo Against Cancer?
    Vitamin C & Antibiotics: A Potent Duo Against Cancer?
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    Written By: Xuan Pham
    3
    JUN 13, 2017
    Drug Discovery & Development
    A Novel Drug for Slowing the Progression of Heart Valve Disease
    A Novel Drug for Slowing the Progression of Heart Valve Disease
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    Written By: Kara Marker
    3 1
    JUN 07, 2017
    Cell & Molecular Biology
    Accounting for Gender Differences in Scientific Research
    Accounting for Gender Differences in Scientific Research
    It's only been in the past decade or so that scientists have begun to realize that there is more to sex differences than ...
    Written By: Carmen Leitch
    2
     
     
  • JUN 03, 2017
    Chemistry & Physics
    Can You Hear that Laser Beam: a New Photoacoustic Imaging Technique that Explores Anatomy and Physiology with High Spatiotemporal Resolution
    Can You Hear that Laser Beam: a New Photoacoustic Imaging Technique that Explores Anatomy and Physiology with High Spatiotemporal Resolution
    Can you imagine pointing a flash light toward a cave and hearing the echo from within? No? The analogy appears absurd, b ...
    Written By: Daniel Duan
    1
    MAY 31, 2017
    Immunology
    Hybrid Molecule Delivers 1-2 Punch to Find & Attack Nasty Staph Bacteria
    Hybrid Molecule Delivers 1-2 Punch to Find & Attack Nasty Staph Bacteria
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    Written By: Invisiverse Puccio
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    MAY 30, 2017
    Health & Medicine
    Genetic Study of Psoriasis Reveals Clues About Disease Causation
    Genetic Study of Psoriasis Reveals Clues About Disease Causation
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    MAY 28, 2017
    Microbiology
    Polyomavirus Gets Into a Cell Using its Machinery
    Polyomavirus Gets Into a Cell Using its Machinery
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    MAY 22, 2017
    Neuroscience
    The Molecular Mechanism of Lithium in Bipolar Disorder
    The Molecular Mechanism of Lithium in Bipolar Disorder
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    Written By: Brenda Kelley Kim
    2
     
     
  • MAY 17, 2017
    Cell & Molecular Biology
    New Connection Between Receptors Discovered in the Brain
    New Connection Between Receptors Discovered in the Brain
    Researchers have reported the discovery of a novel signaling pathway in the brain, and the findings may have implication ...
    Written By: Carmen Leitch
    2
    MAY 09, 2017
    Immunology
    Pumping Up T Cells to Better Fight Cancer
    Pumping Up T Cells to Better Fight Cancer
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    MAY 05, 2017
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    APR 20, 2017
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