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    Drug screening with cancer cells

    Developing safe and effective drugs to treat cancer involves intensive studies using various model systems including in vitro analysis with cancer cells. Cancer cell lines are generated from the tissue of cancer patients. Developmental drugs are then used to treat the cells in a laboratory setting where the effects on cell growth and death can be monitored.

    Webinars

    • OCT 11, 2018 | 9:00 AM
      Destabilization and Degradation of MYC: More Ways Than One
      Destabilization and Degradation of MYC: More Ways Than One
      The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
      Speaker: Jason De Melo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 7:30 AM
      Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
      Keynote Presentation: In Advanced Cancers Curative Therapies Must...
      In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
      Speaker: Krastan Blagoev, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 11, 2018 | 6:00 AM
      Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
      Revealing the Hidden Landscape of Structural Variants in Cancer...
      PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
      Speaker: Jonas Korlach, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 1:30 PM
      Discovery of Biomarkers Predictive of Anticancer Drug Response in Preclinical Settings
      Discovery of Biomarkers Predictive of Anticancer Drug Response...
      Some Abstract...
      Speaker: Benjamin Haibe-Kains, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
      To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
      Speaker: Jerome Galon, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 12:00 PM
      Sample to Insight:  Everything You Need to Know About RNA Sequencing
      Sample to Insight: Everything You Need to Know About RNA Sequencing
      RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
      Speaker: Jonathan Shaffer, PhD, MBA
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 10, 2018 | 9:00 AM
      Understanding Cancer Through Whole-Genome Screening
      Understanding Cancer Through Whole-Genome Screening
      High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
      Speaker: Andrew Ravanelli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: MilliporeSigma
      5
      OCT 10, 2018 | 9:00 AM
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
      Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
      In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
      Speaker: Paul Sondel, MD, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      1
      OCT 10, 2018 | 7:30 AM
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
      Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
      Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
      Speaker: Karin Rodland, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      2
      OCT 10, 2018 | 6:00 AM
      Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
      Precise Detection of T-Cell Receptors Using RNAseq With Unique...
      Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
      Speaker: Samuel Rulli, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: QIAGEN
      1
      OCT 09, 2018 | 8:00 AM
      GMP Ancillary Materials for Cell and Gene Therapy Manufacturing: What to consider and when to make the switch
      GMP Ancillary Materials for Cell and Gene Therapy Manufacturing:...
      DATE: October 9, 2018TIME: 08:00am PDT, 11:00pm EDT Have you ever wondered what to consider when you are selecting ancillary materials for your cell therapy clinical research...
      Speaker: Kasey Kime , Eric Roos
      Sponsored By: Thermo Fisher Scientific/Gibco
      12
      OCT 03, 2018 | 9:00 AM
      Mechanisms of Myeloid Immunosuppression:  Functional Characterization of the Tumor Microenvironment Using Single and Multiplex IHC
      Mechanisms of Myeloid Immunosuppression: Functional Characterization...
      DATE:  October 3, 2018TIME:  9:00am PDT, 12:00pm EDT Infiltrating myeloid cells constitute a significant component of the suppressive tumor microenvironment (TME) a...
      Speaker: Christopher Grange
      Sponsored By: Cell Signaling Technology
      3
      SEP 26, 2018 | 1:30 PM
      Two-Dimensional and Three-Dimensional Cell Culture, Does Dimension Really Matter?
      Two-Dimensional and Three-Dimensional Cell Culture, Does Dimension...
      When looking to answer complex biological questions, using in vitro techniques, you want the model that best reflects the in vivo condition.  For decades two-dimensional cell culture has...
      Speaker: Carlemi Calitz, PhD
      Presented at: Cell Biology Virtual Event Series 2018
      2
      SEP 26, 2018 | 9:00 AM
      How to Utilize the Power of CRISPR in Your Research
      How to Utilize the Power of CRISPR in Your Research
      CRISPR has revolutionized how we do science in a similar way PCR changed the face of molecular biology. Learn how to take advantage of this phenomenal technology in the easiest way with Synth...
      Speaker: Ania Wronski, PhD
      Presented at: Cell Biology Virtual Event Series 2018
      Sponsored By: Synthego
      1
      SEP 18, 2018 | 8:00 AM
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
      DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
      Speaker: Judd Hultquist, PhD
      Sponsored By: Horizon Discovery
      7
      SEP 12, 2018 | 12:00 PM
      ONETest PathoGenome: A Target Hybridization-Based Next-Generation Sequencing Assay to Tackle Undiagnosed Infections
      ONETest PathoGenome: A Target Hybridization-Based Next-Generation...
      Every year, approximately 800,000 critically ill patients are hospitals in the USA with undiagnosed infections. The only option is to treat these patients with broad-spectrum antimicrobial th...
      Speaker: Mohammad Qadir, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      1 1
      SEP 11, 2018 | 7:00 AM
      Answering the Challenges of Cell Viability and Reporter Gene Assays Screening Cost and Quality
      Answering the Challenges of Cell Viability and Reporter Gene Assays...
      DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
      Speaker: Vincent Dupriez, PhD , Jeanine Hinterneder, PhD , Maria Kuzikov, MSc
      Sponsored By: Revvity
      5
      AUG 09, 2018 | 7:00 AM
      3D Cell Cultures and Tissue Clearing: A High Content Confocal Platform for the Complete 3D Characterization of Advanced Cell Models
      3D Cell Cultures and Tissue Clearing: A High Content Confocal...
      With the advent of cost effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
      Speaker: Michael Johnson, PhD
      Sponsored By: Thermo Fisher Scientific
      7
      AUG 07, 2018 | 8:00 AM
      Using Reference Standards to Validate your NGS Oncology Workflow
      Using Reference Standards to Validate your NGS Oncology Workflow
      DATE: August 7, 2018TIME: 08:00AM PDT, 11:00AM EDTWe are currently at an exciting precipice in clinical oncology management, where an increased rate of biomarker identification is drivi...
      Speaker: Hannah Child, PhD
      Sponsored By: Horizon Discovery
      10 1
      JUN 20, 2018 | 12:00 PM
      Precision Medicine: The Way Forward!
      Precision Medicine: The Way Forward!
      Recent advancements in the precision medicine field have presented a great promise to provide innovative solutions to pharmaceutical and healthcare industry to help transform medicine. By fin...
      Speaker: Prasun Mishra, MsC, PhD
      Presented at: Precision Medicine Virtual Event Series 2018
      1
      MAY 24, 2018 | 9:30 AM
      Turning to a new dimension in cell culture for cancer research
      Turning to a new dimension in cell culture for cancer research
      DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
      Speaker: Carlemi Calitz, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      14 2
      APR 17, 2018 | 8:00 AM
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
      DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
      Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      7 1
      MAR 27, 2018 | 9:00 AM
      How to use CRISPR-Cas9 for knockout, knock-in and gene activation
      How to use CRISPR-Cas9 for knockout, knock-in and gene activation
      DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
      Speaker: Amanda Haas
      Sponsored By: Horizon Discovery
      23 15
      FEB 22, 2018 | 9:00 AM
      Investigating colorectal cancer using epithelial organoid cultures
      Investigating colorectal cancer using epithelial organoid cultures
      DATE: February 22, 2018TIME: 09:00am PST, 12:00pm EST, 06:00pm CEST(Europe)Colorectal cancer (CRC) develops during a multi-step process from small lesions of the intestinal epithelium....
      Speaker: Kai Kretzschmar, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      9 3
    OCT 11, 2018 | 9:00 AM
    Destabilization and Degradation of MYC: More Ways Than One
    Destabilization and Degradation of MYC: More Ways Than One
    The oncogenic transcription factor c-MYC (MYC) is deregulated, and often overexpressed, in more than 50% of cancers. MYC deregulation is associated with poor prognosis and aggressive disease,...
    Speaker: Jason De Melo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 7:30 AM
    Keynote Presentation: In Advanced Cancers Curative Therapies Must Target All Cancer Cells
    Keynote Presentation: In Advanced Cancers Curative Therapies Must...
    In the past two decades a small number of infrequently dividing cells have been proposed as the source of multi-drug resistance during cancer treatment. These cells identified by their expres...
    Speaker: Krastan Blagoev, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 11, 2018 | 6:00 AM
    Revealing the Hidden Landscape of Structural Variants in Cancer Genomes
    Revealing the Hidden Landscape of Structural Variants in Cancer...
    PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying...
    Speaker: Jonas Korlach, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 1:30 PM
    Discovery of Biomarkers Predictive of Anticancer Drug Response in Preclinical Settings
    Discovery of Biomarkers Predictive of Anticancer Drug Response...
    Some Abstract...
    Speaker: Benjamin Haibe-Kains, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 12:00 PM
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    Integrative Cancer Immunology and Novel Concepts of Cancer Evolution
    To date the anatomic extent of tumor (TNM-classification) has been by far the most important factors to predict the prognosis of cancer patients. However, this classification provides limited...
    Speaker: Jerome Galon, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
     
     
  • OCT 10, 2018 | 12:00 PM
    Sample to Insight:  Everything You Need to Know About RNA Sequencing
    Sample to Insight: Everything You Need to Know About RNA Sequencing
    RNA sequencing unlocks the mysteries hidden in the transcriptome. Whether your goal is gene expression analysis, gene fusion analysis, SNP analysis or miRNA expression analysis, achieving hig...
    Speaker: Jonathan Shaffer, PhD, MBA
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
    OCT 10, 2018 | 9:00 AM
    Understanding Cancer Through Whole-Genome Screening
    Understanding Cancer Through Whole-Genome Screening
    High-throughput screening is widely useful in identifying genes and pathways that drive changes in cell behavior such as cell cycle regulation, metastasis, and drug resistance.  Millipor...
    Speaker: Andrew Ravanelli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: MilliporeSigma
    5
    OCT 10, 2018 | 9:00 AM
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate and Adaptive Antitumor Immunity
    Using Radiotherapy, Tumor-Reactive mAb and IL2 to Engage Innate...
    In prior work, we have pursued how tumor reactive monoclonal antibody (mAb), together with activators of innate immune cells, like NK cells, can augment antibody dependent cell-mediated cytot...
    Speaker: Paul Sondel, MD, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    1
    OCT 10, 2018 | 7:30 AM
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights for Prognosis and Therapy
    Keynote Presentation: Proteogenomics and Cancer Biology: Insights...
    Molecular analyses of cancer biology have tended to segregate between a focus on nucleic acids – DNA, RNA and their modifications – and a focus on proteins and protein function. P...
    Speaker: Karin Rodland, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    2
    OCT 10, 2018 | 6:00 AM
    Precise Detection of T-Cell Receptors Using RNAseq With Unique Molecular Indexing
    Precise Detection of T-Cell Receptors Using RNAseq With Unique...
    Understanding the immune repertoire is an important aspect of immuno-oncology research, which can be used to gather insights into the function and overall status of the immune system. We have...
    Speaker: Samuel Rulli, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: QIAGEN
    1
     
     
  • OCT 09, 2018 | 8:00 AM
    GMP Ancillary Materials for Cell and Gene Therapy Manufacturing: What to consider and when to make the switch
    GMP Ancillary Materials for Cell and Gene Therapy Manufacturing:...
    DATE: October 9, 2018TIME: 08:00am PDT, 11:00pm EDT Have you ever wondered what to consider when you are selecting ancillary materials for your cell therapy clinical research...
    Speaker: Kasey Kime , Eric Roos
    Sponsored By: Thermo Fisher Scientific/Gibco
    12
    OCT 03, 2018 | 9:00 AM
    Mechanisms of Myeloid Immunosuppression:  Functional Characterization of the Tumor Microenvironment Using Single and Multiplex IHC
    Mechanisms of Myeloid Immunosuppression: Functional Characterization...
    DATE:  October 3, 2018TIME:  9:00am PDT, 12:00pm EDT Infiltrating myeloid cells constitute a significant component of the suppressive tumor microenvironment (TME) a...
    Speaker: Christopher Grange
    Sponsored By: Cell Signaling Technology
    3
    SEP 26, 2018 | 1:30 PM
    Two-Dimensional and Three-Dimensional Cell Culture, Does Dimension Really Matter?
    Two-Dimensional and Three-Dimensional Cell Culture, Does Dimension...
    When looking to answer complex biological questions, using in vitro techniques, you want the model that best reflects the in vivo condition.  For decades two-dimensional cell culture has...
    Speaker: Carlemi Calitz, PhD
    Presented at: Cell Biology Virtual Event Series 2018
    2
    SEP 26, 2018 | 9:00 AM
    How to Utilize the Power of CRISPR in Your Research
    How to Utilize the Power of CRISPR in Your Research
    CRISPR has revolutionized how we do science in a similar way PCR changed the face of molecular biology. Learn how to take advantage of this phenomenal technology in the easiest way with Synth...
    Speaker: Ania Wronski, PhD
    Presented at: Cell Biology Virtual Event Series 2018
    Sponsored By: Synthego
    1
    SEP 18, 2018 | 8:00 AM
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    High-throughput CRISPR-Cas9 Genome Engineering in Primary T Cells
    DATE: September 18,2018TIME: 08:00am PDT, 11:00am EDT CRISPR-Cas9 gene editing strategies have revolutionized our ability to engineer the genomes of diverse cell types and sp...
    Speaker: Judd Hultquist, PhD
    Sponsored By: Horizon Discovery
    7
     
     
  • SEP 12, 2018 | 12:00 PM
    ONETest PathoGenome: A Target Hybridization-Based Next-Generation Sequencing Assay to Tackle Undiagnosed Infections
    ONETest PathoGenome: A Target Hybridization-Based Next-Generation...
    Every year, approximately 800,000 critically ill patients are hospitals in the USA with undiagnosed infections. The only option is to treat these patients with broad-spectrum antimicrobial th...
    Speaker: Mohammad Qadir, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    1 1
    SEP 11, 2018 | 7:00 AM
    Answering the Challenges of Cell Viability and Reporter Gene Assays Screening Cost and Quality
    Answering the Challenges of Cell Viability and Reporter Gene Assays...
    DATE: September 11, 2018TIME: 07:00AM PDTWith increasing safety requirements, and time and financial pressure, the development of new drugs, and the execution of basic research p...
    Speaker: Vincent Dupriez, PhD , Jeanine Hinterneder, PhD , Maria Kuzikov, MSc
    Sponsored By: Revvity
    5
    AUG 09, 2018 | 7:00 AM
    3D Cell Cultures and Tissue Clearing: A High Content Confocal Platform for the Complete 3D Characterization of Advanced Cell Models
    3D Cell Cultures and Tissue Clearing: A High Content Confocal...
    With the advent of cost effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-...
    Speaker: Michael Johnson, PhD
    Sponsored By: Thermo Fisher Scientific
    7
    AUG 07, 2018 | 8:00 AM
    Using Reference Standards to Validate your NGS Oncology Workflow
    Using Reference Standards to Validate your NGS Oncology Workflow
    DATE: August 7, 2018TIME: 08:00AM PDT, 11:00AM EDTWe are currently at an exciting precipice in clinical oncology management, where an increased rate of biomarker identification is drivi...
    Speaker: Hannah Child, PhD
    Sponsored By: Horizon Discovery
    10 1
    JUN 20, 2018 | 12:00 PM
    Precision Medicine: The Way Forward!
    Precision Medicine: The Way Forward!
    Recent advancements in the precision medicine field have presented a great promise to provide innovative solutions to pharmaceutical and healthcare industry to help transform medicine. By fin...
    Speaker: Prasun Mishra, MsC, PhD
    Presented at: Precision Medicine Virtual Event Series 2018
    1
     
     
  • MAY 24, 2018 | 9:30 AM
    Turning to a new dimension in cell culture for cancer research
    Turning to a new dimension in cell culture for cancer research
    DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
    Speaker: Carlemi Calitz, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    14 2
    APR 17, 2018 | 8:00 AM
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
    DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
    Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    7 1
    MAR 27, 2018 | 9:00 AM
    How to use CRISPR-Cas9 for knockout, knock-in and gene activation
    How to use CRISPR-Cas9 for knockout, knock-in and gene activation
    DATE: March 27, 2018TIME: 09:00am PDT, 12:00pm EDTThe rapid adoption and ease of use of CRISPR-Cas9 has driven the development of applications for gene knockout, precise gene editing, a...
    Speaker: Amanda Haas
    Sponsored By: Horizon Discovery
    23 15
    FEB 22, 2018 | 9:00 AM
    Investigating colorectal cancer using epithelial organoid cultures
    Investigating colorectal cancer using epithelial organoid cultures
    DATE: February 22, 2018TIME: 09:00am PST, 12:00pm EST, 06:00pm CEST(Europe)Colorectal cancer (CRC) develops during a multi-step process from small lesions of the intestinal epithelium....
    Speaker: Kai Kretzschmar, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    9 3
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